AVID 18F-AV-1451 / A Clinico-Pathological
Study of the Correspondence Between 18F-AV-1451 PET Imaging and Post-Mortem
Assessment of Tau Pathology
The purpose of this study is to see how well the
investigational drug 18F-AV-1451 used as a brain imaging drug in positron
emission tomography (PET). PET is a way to look at a picture of the inside of
the body. 18F-AV-1451 works in the detection of protein deposits in the brain.
18F-AV-1451 sticks to a special type of protein in the brain called tau protein
and can be seen in pictures taken using a PET/CT scanner. This protein has been
linked to people who have dementia or Alzheimer’s disease or may develop Alzheimer’s
disease. Pictures of the brain made using the study drug during the life of
study participants will be compared to results of brain autopsy after death.
Autopsy is the examination of the body or body parts after death.
- Men and Women
Age 50 years old and older
Have a projected life expectancy of 6 months or less
- Tests of memory and thinking
- Have a study partner – a friend
or relative who can accompany the volunteer to clinic visits
Consent to brain donation upon death
- Compensation for time and travel
Tim Collare: 336-716-6463