Key Adverse Events Following Childhood Cancer

What we are studying

Incredible progress has been made in curing childhood cancer. With all this success has come the awareness that childhood cancer treatment may lead to complications in some patients and sometimes this is after their treatment is completed. These late-occurring complications include cardiac dysfunction (a damaged heart that is unable to circulate blood efficiently), avascular necrosis (poor blood supply to an area of the bone that causes permanent bone damage), stroke (blood flow to the brain is interrupted), or a second cancer. The goal of this study is to identify patients who are more likely to develop a late-occurring complication(s). If we know who is at a greater risk of developing a late-occurring complication(s), then we can observe those patients more closely, in order to prevent the complication from occurring or to find the complication early.

Who we are studying

  • Men and Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • All Ages

Eligibility Criteria

  • Diagnosis of primary cancer at age 21 or younger
  • Development of one of the following key adverse events at any time following initiation of cancer therapy:
    • Cardiac dysfunction
    • Ischemic stroke
    • Subsequent malignant neoplasm
    • Avascular necrosis

What is involved

  • Collection of a biological sample (blood or check cells)
  • Questionnaire detailing family history and health history

Compensation

None

Contact Information

Study Coordinator
Joy Mitchell
Email
jmitchel@wakehealth.edu
Phone
336-716-2748

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.