Comparison of Treatments for Endometrial Cancer

What we are studying

The main purpose of this study is to compare radiation therapy in combination with weekly treatment with the chemotherapy drug cisplatin to the standard treatment for this type of cancer. The standard treatment for patients with your type of cancer is radiation therapy alone. Radiation therapy is a cancer treatment that uses radiation beams from outside your body, or radioactive seeds or pellets placed directly into the tissue to kill cancer cells. Radiation therapy alone has not been very effective in treating large tumors that recur (come back) in the pelvis, lymph nodes or vagina. Radiation therapy in combination with weekly treatment with the chemotherapy drug cisplatin has been found to be very effective in treating patients with advanced cervical cancers. Another purpose of the study is to evaluate the side effects of the combination of radiation therapy and cisplatin.

Who we are studying

  • Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18+

Eligibility Criteria

  • Confirmed diagnosis of recurrent endometrial cancer
  • Have previously been treated with surgery (complete hysterectomy and bilateral salpingooophorectomy)
  • Previous hormone therapy or chemotherapy was completed at least 6 months before enrolling in the study

What is involved

  • Patients will receive study treatment for about 6-7 weeks
  • Follow-Up exams every 3 months for the first 2 years and then every 6 months for the next 3 years

Compensation

None

Contact Information

Study Coordinator
Melissa Swain
Email
mswain@wakehealth.edu
Phone
336-716-9428

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.