What we are studying
This study is designed to help understand how muscles become weaker in ALS.
The purpose of this trial is to study muscle and nerve connection to the muscle (neuromuscular junction) at different stages of ALS. There, the ends of nerve fibers connect to special sites on the muscle's membrane. These membranes contain receptors that enable the muscle to respond to a chemical messenger released by the nerve. After a nerve stimulates a muscle at this junction, an electrical impulse flows through the muscle, causing it to contract.
It is known that nerve cells called “motor neurons” die in brain and spinal cords of people with ALS. However previous studies have shown that the death of these cells occurs late in the disease process. This trial focuses on thigh muscles to better understand the underlying disease process in ALS.
$100 to compensate for time and travel expenses