Use of Vitamin D Supplement in Patients with Resectable Rectal Cancer

What we are studying

This study will look at standard of treatment for your condition which is chemotherapy and radiation therapy (CRT) and compare that to standard treatment plus a vitamin D supplement. We aim to assess whether the treatment with a vitamin D supplement is tolerable and has any effect on rectal cancer cells. The use of the Vitamin D supplement in this study is investigational.

Who we are studying

Men and Women
Races:
- White
- African American
- Asian
- American Indian or Alaska Native
- Native Hawaiian or Pacific Islander
- Other
All Ethnicities
Ages 18+

Eligibility Criteria

Diagnosed with rectal cancer that has not spread (metastases) and is resectable

What is involved

Study involvement will last from time of signing the consent for until one month after surgery to resect the cancer
Study activities will occur weekly during chemotherapy and radiation therapy; 2 weeks after chemotherapy and radiation therapy; and at surgical resection