What we are studying
This study is being done because standard chemotherapy for AR-ALL does not get rid of the cancer in all children with AR-ALL. The overall goal of Part I of this study is to collect information about Standard Risk Acute Lymphoblastic Leukemia (SR-ALL) and about the effects of the first phase of treatment, called Induction. The overall goal of Part II of this study is to collect information on the leukemia and the effects of different treatments. Phase III of this study is testing whether modifications in Maintenance therapy will improve outcomes while minimizing side effects. Side effects are unintended and unwanted results of treatment.