Therapy Based on PET Scans for Bulkly Stage I and II Hodgkin Lymphoma

What we are studying

This research is being done in order to improve treatment outcomes in patients diagnosed with bulky, early stage Hodgkin lymphoma and to reduce the side effects that are associated with radiation, which is used in current treatments. As part of the evaluation of the effectiveness of the chemotherapy treatment, PET scans will be obtained during the course of your therapy. We will evaluate the usefulness of this PET scan to determine whether radiation may be left out in the treatment of your disease if the PET scan shows you have responded to chemotherapy alone. In addition, a small percentage of patients may have disease that is not adequately treated with ABVD and radiotherapy. We hope to identify this group of patients using early PET scans and will change to a different chemotherapy treatment.

Who we are studying

  • Men and Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18 - 60

Eligibility Criteria

  • Diagnosed with Hodgkin Lymphoma
  • Patients may have had only one cycle of ABVD prior to enrolling in study
  • No currently active second malignancies other than non-melanoma skin cancers

What is involved

  • Study treatment will last at least 6 months
  • Follow-Up visits will occur: every 3 months for one year; every 6 months for years 2-3; and then yearly for a maximum of 10 years



Contact Information

Study Coordinator
Elizabeth Sapp

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.