Maternal Outcomes in Women with Epilepsy

What we are studying

Most women with epilepsy have normal pregnancies, but appear to be at risk for problems during pregnancy (e.g., seizures, change in medications, depression, c-sections) and adverse outcomes in their children (e.g., thinking or behavioral problems). The purpose of this observational study is to establish the relationship between antiepileptic drug (AED) exposure and outcomes in the mother and child as well as describe and explain the variability in AED exposure and response. For pregnant women, the study will follow their babies for any signs of developmental problems with free Neuropsych testing until the age of 3 years. The results of these tests will be available to the treating pediatricians if needed for early intervention.

Who we are studying

  • Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18+

Eligibility Criteria

  • Pregnant women with epilepsy up to 20 weeks gestation
  • Pregnant women without epilepsy up to 20 weeks gestation
  • Non-Pregnant women with epilepsy

What is involved

  • 11 study visits and 9 telephone contacts
  • Visits will occur about every 3 months
  • Patient will also receive an iPod 4 touch to track their seizures during the study which they get to keep after the study is done
  • Babies will be followed for 3 years after they are born for any signs of developmental problems with free Neuropsych testing

Compensation

Pregnant participants will receive $1000 for completing all scheduled study visits, Non-pregnant participants will receive $250 for completing all scheduled study visits.

Contact Information

Study Coordinator
Sara Vaughan
Email
svaughan@wakehealth.edu
Phone
336-716-8694
Principal Investigator
Maria Sam, MD

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.