Study of the Effects of Intranasal Insulin Spray on Memory after a Mild Stroke

What we are studying

The purpose of this study is to see if intranasal insulin might improve memory and functioning recovery in patients over 50 who have had a recent mild stroke. These patients will use the nasal spray study treatment for three weeks and have various stroke and memory tests at baseline and throughout the 6 month study.

Who we are studying

  • Men and Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 50 - 89

Eligibility Criteria

  • Diagnosed with mild ischemic stroke
  • Able to sign consent
  • Have a caregiver
  • Live within a reasonable driving distance from Wake Forest Baptist Medical Center
  • Severe stroke deficits that prohibit participation in cognitive testing
  • Diabetics taking drugs or insulin to lower glucose levels
  • Psychiatric disorders
  • Severe head trauma
  • Alcoholism
  • Neurologic disorders other than stroke
  • Renal or liver disease
  • Chronic obstructive pulmonary disease
  • Unstable cardiac disease
  • Those with prior deficits in activities of daily living

What is involved

  • 4 clinic visits with cognitive (memory) testing
  • Questionnaires
  • Caregiver questionnaires
  • 3 blood draws which will occur at 3 of the clinic visits.


$25.00 gift card

Contact Information

Study Coordinator
Cheryl Bushnell, M.D.
Principal Investigator
Cheryl Bushnell, M.D.

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.