Low-Dose Tamoxifen For Radiation-Induced Breast Cancer Risk Reduction

What we are studying

The purpose of this study is to determine whether two years of low dose tamoxifen has an effect on laboratory tests and other evaluations associated with the risk of breast cancer in female cancer survivors treated with chest radiation at a young age for certain cancers that commonly occur in childhood, adolescence, and young adulthood, such as Hodgkin lymphoma and Ewing sarcoma. Another purpose is to measure the safety and tolerability of tamoxifen according to laboratory tests and information on side effects collected from questionnaires.

Who is Eligible

• Genders:
  • Women
• Races:
  • White
  • African American
  • Asian
  • American Indian or Alaska Native
  • Native Hawaiian or Pacific Islander
  • Other
• All Ethnicities
• Ages 25+

Eligibility Criteria

• Exposure to radiation delivered to the chest
• Axilla
• And/Or supraclavicular areas

What is involved

• Physical Examination
• Blood draws for chemistry evaluations
• Urine sample
• Screening mammogram
• Breast exams
• Optional research blood and tissue
• And questionnaires

Compensation

Parking compensation for research visits Gift card(s)

Contact Information

Study Coordinator

Stacey Lewis, RN

Email

stalewis@wakehealth.edu

Phone

336-713-6927

Principal Investigator

Susan Melin, MD