BEAM (Brain Energy And Memory Study)

What we are studying

The BEAM study will examine the effects of a low-carbohydrate and higher-carbohydrate diet on people with mild memory loss and those with pre-diabetes. Information collected will help determine changes in cognitive function, brain structure and function, and levels of certain proteins and hormones in body fluids. This information will be collected from 75 people and compared between three study groups. Group 1 will include 15 people with no memory problems or concerns. Group 2 will include 30 people with no memory problems or concerns, but do have pre-diabetes. Group 3 will include 30 people with mild memory problems.

Who we are studying

  • Men and Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 55 - 85

Eligibility Criteria

  • Study partner available to attend minimum of 3 visits
  • Stable medical condition for 3 months prior to screening
  • Stable medications for 4 weeks prior to screening
  • Ability to complete baseline visits
  • Hba1c and fasting glucose within normal range(healthy/MCI
  • Early AD) group or pre-diabetic range (at risk/MCI/early AD) groups.

What is involved

  • Questionnaires at each visit (inclues adverse event review)
  • Physical
  • Neurological exam
  • Vitals/Weight
  • Review medications
  • Memory testing
  • Blood collection
  • Lumbar puncture
  • DEXA scan
  • MRI
  • Pulse wave velocity
  • Individule & group diet education and telephone check.


Group 1 - total of $80; Groups 2 & 3 - total of $295

Contact Information

Study Coordinator
Tim Collare
Principal Investigator
Suzanne Craft, PhD

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.