What we are studying

The Connect research study will look at an experimental drug that is being developed for Alzheimer’s disease (AD). “Experimental” means that the study drug has not been approved by the US Food and Drug administration for the treatment of AD. The purpose of this research study is to determine whether it is safe and effective in slowing decline in brain metabolism, memory and daily function in people with Alzheimer’s disease (AD).

Who we are studying

  • Men and Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • Hispanic or Latino
  • Ages 55 - 85

Eligibility Criteria

  • NIA-­?Alzheimer’S Association core clinical criteria for probable AD
  • MMSE score between 18 and 26
  • Stability of permitted medications for 4 weeks
  • Study partner is available who has frequent contact (average of 10 hours per week) with the participant
  • Good general health with no disease expected to interfere with the study
  • Women must be two years post-menopausal or surgically sterile
  • Completed six grades of education or has good work history.

What is involved

  • 2 MRI scans
  • 1 PET scan
  • 2 fasting FDG PET scans
  • 2 ECGs
  • Memory and thinking tests
  • 2 optional lumbar punctures
  • Functional and behavioral questionnaires
  • Medication review
  • Blood
  • Vitals and weight will be collected 13 times
  • Participants will take three tablets or placebo once daily by mouth for one year.


Screening Visit 1 $25.00 Screening Visit 1a (MRI Scan) $25.00 Screening Visit 1b (PET Scan) $50.00 Baseline Visit 2 $120.00 Baseline Lumbar Puncture (Optional) $100.00 Visits 3, 4, 5, 6, 8, 10 & 12 $40.00 per completed study visit ($280) Visit

Contact Information

Study Coordinator
Tim Collare
Principal Investigator
Suzanne Craft, PhD

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.