Biomarkers for Acute Stroke Etiology (BASE)

What we are studying

Despite advances in medical care, the cause of 30% of strokes remains unknown. The purpose of this research study is to collect blood samples that can be stored and later analyzed to find information that might lead to new tests or treatments for acute strokes. The use of the biomarkers (blood components) within the blood samples may allow doctors to discover the cause of strokes, and help to determine the best course of treatment.

Who is Eligible

• Genders:
  • Men
  • Women
• Races:
  • White
  • African American
  • Asian
  • American Indian or Alaska Native
  • Native Hawaiian or Pacific Islander
  • Other
• All Ethnicities
• Ages 18+

Eligibility Criteria

• Stroke or TIA arm:
  • Symptoms suggestive of acute ischemic stroke or transient ischemic attack (TIA)
• Arrive at the ED within 8 hours of symptoms
• No other pathology that would cause symptoms (vascular malformation
• Hemorrhage
• Tumor or abscess)
• Stroke/TIA arm and Control arm:
  • No central nervous system infections
• No head trauma or stroke in the past 30 days
• No primary or metastatic brain cancer
• Cannot have active cancer
• No autoimmune diseases or chronic infectious diseases
• Cannot have had major surgery within past three months.

What is involved

• Stroke or TIA arm: three blood draws
• Control arm: one blood draw

Compensation

None

Contact Information

Study Coordinator

Stephanie Elliott

Email

sbradsha@wakehealth.edu

Phone

336-716-5943

Principal Investigator

Brian Hiestand, MD