Effect of Weight Loss or Weight Control on Mobility, Muscle and Bone Health

What we are studying

The purpose of this study is to see if following a high protein weight loss program improves physical function by improving body composition compared to obese, older adults who maintain their weight.

Who we are studying

  • Men and Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • Hispanic or Latino
  • Ages 65 - 79

Eligibility Criteria

  • BMI = 30-40 kg/m2
  • Have some health problems including trouble walking or doing every day activities
  • Willing and able to follow the dietary protocol
  • Not be involved in another research study
  • Not dependent on cane or walker
  • No evidence of clinical depression or eating disorder

What is involved

  • 2-Part screening visit and 2-part end of study intervention visit (at 24 weeks) to the CRU and Reynolda Campus of Wake Forest University
  • Tests for physical function
  • Tests for muscle strength
  • Tests for bone density and body composition
  • Blood draws
  • Additional mid-point visit to the Reynolda Campus Biomechanics Lab
  • Bi-Monthly visits to group intervention sessions for 6 months. If randomized to weight loss arm
  • Participants will be asked to follow a dietitian-supervised calorie-controlled high protein diet with supplements



Contact Information

Study Coordinator
Jessica Sheedy
Principal Investigator
Kristen Beavers

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.