A study looking at targeted therapy according to tumor markers for people with meningiomas

What we are studying

Study participants are being asked to take part in this study because you have a meningioma which has gotten bigger or grew back after treatment. Meningiomas are tumors that grow on the covering of the brain. Because they grow on the brain covering, they can push on the brain and cause symptoms. Some meningiomas can be watched, and some require treatment. Study participants have required treatment. People who are not in a study are usually treated with either surgery, radiation, or with drugs. These treatments can reduce symptoms and may stop the tumor from growing for several months or more.

Who is Eligible

  • Genders:
    • Men
    • Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18 - 80

Eligibility Criteria

  • Presence of SMO or NF2 mutation in tumor sample

What is involved

  • If your tumor sample has the SMO gene
  • You will receive the study drug Vismodegib. If your tumor sample has the NF2 gene
  • You will receive the study drug GSK2256098. If your tumor does not show either gene
  • You will not receive any study drug.


Parking will be validated for all study related visits.

Contact Information

Study Coordinator
Ashley Fansler, RN

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.