Permanent vs. Delayed-absorbable monofilament suture for vaginal graft during hysterectomy

What we are studying

The purpose of this research study is to compare two different suture types that are used to attach vaginal mesh that is typically used in women undergoing robotic or laparoscopic total hysterectomy and sacrocolpopexy (attachment of the vagina to the sacral promontory).

Who we are studying

  • Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18+

Eligibility Criteria

  • Inclusion:
    • Apical with anterior or posterior vaginal prolapse
  • Eligible for robotic or laparoscopic sacral colpopexy
  • Desires surgical treatment for primary
  • Symptomatic uterovaginal prolapse
  • Willing to undergo hysterectomy Exclusion:
    • Patients with prior hysterectomy
  • Patients who are not surgical candidates due to medical comorbidities
  • Current foreign body complications
  • Desires uterine conservation
  • Anticipated inability to follow up
  • Pregnant or intends to become pregnant
  • Active systemic infection
  • History of pelvic organ cancer
  • Current or prior radiation therapy in the pelvic area
  • Systemic steroid use in past month
  • Immunosuppressive or immunomodulatory treatment within last 3 months
  • Systemic connective tissue disease
  • Poorly controlled diabetes mellitus
  • Those requiring concomitant rectopexy
  • Subject is unable to conform to steep trendelenburg position
  • Known sensitivity to polypropylene

What is involved

  • Questionnaires are the only research only activities during the study

Compensation

$39.06 for 6 week follow up $78.12 for the 12 month follow up

Contact Information

Study Coordinator
Janet Shuping
Email
jshuping@wakehealth.edu
Phone
336-716-2612
Principal Investigator
Catherine Matthews, M.D.

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.