Analysis of Genomic DNA from your Biopsy or Tissue Samples to Identify Genetic Variations that may Guide Cancer Therapy (Precision Medicine Trial)

What we are studying

The Wake Forest University Health Sciences Comprehensive Cancer is currently having subjects with cancer submit tumor samples and biopsies to Foundation Medicine in order to perform genomic DNA sequencing in order to identify genetic variations that may guide cancer therapy. This process has been ongoing since 2015 and genetic data and accompanying clinical data are available from subjects who have already undergone genomic DNA sequencing. Additional subjects are being screened by their oncologist and will be undergoing genomic DNA sequencing. The cumulative analysis of this genomic sequencing data together with the accompanying clinical data may help use better understand how genetic variations influence the development of cancer and may reveal important information on which cancer therapies.

Who is Eligible

  • All Genders
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18+

Eligibility Criteria

  • Must have already had or be recommended for genomic sequencing of your tumor DNA
  • Must be able to provide consent to use your tumor sample for research

What is involved

  • We will obtain the genomic DNA sequencing data from Foundation Medicine or any other company or laboratory that performed the genomic DNA sequencing. You have already provided permission for your tumor DNA to undergo genomic DNA sequencing and you may have given consent for your tumor to be stored in the WFB Comprehensive Cancer Center Tumor Bank and used for research. We will also be allowed to use the medical information contained in your medical records at Wake Forest University Health Sciences. Once we get the genomic DNA sequencing data and your medical information we will combine your data with data from other cancer patients to perform our research. The process of analyzing your data with other patient’s data will take many years and will be ongoing.


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Contact Information

Study Coordinator
Stacey Lewis
Principal Investigator
Boris Pasche, MD

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.