Brain processes involved in the effects of mindfulness meditation and pain

What we are studying

We are interested in understanding if and how mindfulness-based mental training impacts the experience of pain using heat to the back of the leg that can produce the feeling of pain and brain scans using functional magnetic resonance imaging (fMRI). Study volunteers will be randomly assigned to a mindfulness-based mental training group or a book-listening control group. Project sponsored by NIH/NCCIH R00AT008238

Who is Eligible

  • All Genders
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18 - 60

Eligibility Criteria

  • Healthy and pain free (no ongoing pain)
  • No prior experience with meditation (yoga is okay)

What is involved

  • 6 total visits our facilities
  • Heat stimulation that may produce the feeling of pain
  • Mindfulness-Based mental training or book-listening control
  • Psychological testing
  • One visit to the Wake Forest Center for Biomolecular Imaging center for functional magnetic resonance imaging (fMRI)


Participants will receive $215 for successfully completing ALL study sessions.

Contact Information

Study Coordinator
Dr. Bill Vaughan
Principal Investigator
Dr. Fadel Zeidan

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.