Study the effects of radiation therapy after chemotherapy and surgery

What we are studying

• The main purpose of this clinical trial is to study women like you who have cancer cells in the lymph nodes at the time that the breast cancer is diagnosed and have chemotherapy before surgery that clears the cancer cells from the lymph nodes. This study asks 1) if, after lumpectomy, radiation to the breast and lymph nodes will be better than radiation only to the breast at keeping breast cancer from returning, and 2) if, after mastectomy, radiation to the area where the breast used to be and to the lymph nodes is better than no radiation at keeping breast cancer from returning.

Who is Eligible

  • Genders:
    • Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18 - 90

Eligibility Criteria

  • Pathologic confirmation of axillary nodal involvement

What is involved

  • Study participants will be randomized to Arm 1 - Group 1A - lumpectomy + radiation to the whole breast or Group 1B - mastectomy only or Arm 2 - Group 2A - lumpectomy + radiation to whole breast and lymph nodes or Group 2B - mastectomy + radiation therapy to the chest wall and lymph nodes

Compensation

Parking will be validated for study related visits

Contact Information

Study Coordinator
Stacey Lewis
Email
stalewis@wakehealth.edu
Phone
336-713-6927

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.