DigniCap Scalp Cooling System May Reduce Chemotherapy-Induced Hair Loss
Comprehensive Cancer Center at Wake Forest Baptist Medical Center is the first medical center in the United States to
offer the FDA-cleared DigniCap® scalp cooling system to women undergoing chemotherapy for breast cancer.
The scalp cooling system
features a patented tight-fitting silicone cooling cap that is placed directly
on the head, and an outer neoprene cap that insulates and secures the silicone
cap. The cooling cap is connected to a cooling and control unit with touch screen
prompts. A liquid coolant circulates throughout the silicone cap, delivering
consistent and controlled cooling to all areas of the scalp.
The cap is fitted to the head, and the
temperature of the scalp is lowered, resulting in a constriction of the blood
vessels with reduced delivery of chemotherapy to the scalp, as well as reduced
uptake of the chemotherapy drugs in the scalp. These factors together reduce
the risk of hair loss.
clinical trials of the system, seven out of 10 patients with early stage breast
cancer kept at least 50 percent of their hair.
No severe adverse effects were reported.
Wake Forest Baptist conducted the initial feasibility study in 2010 with the University of California San Francisco, and then went on to participate as one of the five sites conducting the FDA trial. Hematologist-oncologist Susan Melin, MD, led the clinical trials at Wake
Forest Baptist. “We are very pleased to be the first to offer
the DigniCap® system in the U.S. We have
been heavily involved in the clinical trials and I know that the system will be
appreciated by our patients,” said Melin.
Because it is considered an elective treatment, the DigniCap® may not be covered by medical insurance.
The DigniCap® scalp cooling system is manufactured by Dignitana, a Swedish public company based in Lund.