African American Diabetes Heart Study (AA DHS)
This study is dedicated to discovering contributors to genetic factors of heart disease in African Americans with Type 2 diabetes.
Population-Based Studies of Diabetes & Diabetes Complications
- ACCORD is a trial evaluating different treatment strategies in an effort to identify better ways of preventing heart disease events in 10,251 people with established diabetes.
- Look AHEAD is a trial investigating an intensive lifestyle intervention designed to produce and maintain weight loss which can prevent heart disease in overweight and obese people with diabetes.
The Healthy Living Partnership to Prevent Diabetes (HELP Prevent Diabetes)
HELP Prevent Diabetes is a community-based randomized trial of 300 adults who are overweight and at risk for developing diabetes. Participants are randomized into one of 2 treatment groups.
Researchers at the Wake Forest University Primate Center have numerrous studies underway to investigate obesity, insulin resistance and inflammation, and their role in both progression of diabetes and exacerbation of cardiovascular disease.
Researchers in the Wake Forest Institute for Regenerative Medicine are internationally recognized for their expertise in stem cell research and the new and novel field of "reprogramming" cells to carry out new tasks.
Of particular note are research studies supported by a Quantum Grant from the National Institute of Biomedical Imaging and Bioengineering, the Juvenile Diabetes Research Foundation and other sources. This research is aimed at developing insulin secreting ß-cells for research with the ultimate goal of replacing the damaged or missing ß-cells in people with diabetes. The group is currently assessing function by injecting the cells into a mouse model of diabetes.