Edward Abraham, M.D., Professor Internal Medicine-Pulmonary, Critical Care, Allergy, and Immunologic Medicine

Edward Abraham, M.D.

Professor, Pulmonary, Critical Care, Allergy, and Immunologic Medicine

Contact Information

Department: 336-716-4424

Email: eabraham@wakehealth.edu

Education & Training

B.A., Stanford University , 1974
M.D., Stanford University School of Medicine , 1978
Internship, UCLA Hosp, 1979
Residency, UCLA Hosp, 1981
Fellowship, Emergency Medicine, University of California-Los Angeles, 1982
Fellowship, Critical Care Medicine, Los Angeles County Harbor-UCLA Medical Center, 1983

Board Certifications

American Board of Internal Medicine, Internal Medicine, Critical Care Medicine

Memberships

Am Assn Of Immunologists
Shock Society
Soc Of Critical Care Medicine
Southern Society Of Clinical I
Am Coll Of Critical Care Medic
Am Coll Of Physicians
Am Soc Of Clinical Investigati
American Thoracic Society
Assn Of American Physicians
Assn Of Professors Of Medicine

NPI Number

1962456715

Edward Abraham, M.D.

Professor, Pulmonary, Critical Care, Allergy, and Immunologic Medicine

Contact Information

Department: 336-716-4424

Email: eabraham@wakehealth.edu

Recent Publications

Liu G, Abraham E. MicroRNAs in immune response and macrophage polarization. Arterioscler Thromb Vasc Biol. 2013;33(2):170-177.

Bae HB, Tadie JM, Jiang S, Park DW, Bell CP, Thompson LC, Peterson CB, Thannickal VJ, Abraham E, Zmijewski JW. Vitronectin inhibits efferocytosis through interactions with apoptotic cells as well as with macrophages. J Immunol. 2013;190(5):2273-2281.

Tadie JM, Bae HB, Jiang S, Park DW, Bell CP, Yang H, Pittet JF, Tracey K, Thannickal VJ, Abraham E, Zmijewski JW. HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4. Am J Physiol Lung Cell Mol Physiol. 2013;304(5):L342-349.

Tadie J-M, Bae H-B, Banerjee S, Zmijewski JW, Abraham E. Differential activation of RAGE by HMGB1 modulates neutrophil-associated NADPH oxidase activity and bacterial killing. Am J Physiol Cell Physiol. 2012;302(1):C249-256.

Lin W-Y, Tiwari HK, Gao G, Zhang K, Arcaroli JJ, Abraham E. Similarity-based multimarker association tests for continuous traits. Ann Hum Genet. 2012;76(3):246-260.

Alberti MO, Roth JC, Ismail M, Tsuruta Y, Abraham E, Pereboeva L, Gerson SL, Curiel DT. Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation. PLoS ONE. 2012;7(5):e37812.

de Freitas A, Banerjee S, Xie N, Cui H, Davis KI, Friggeri A, Fu M, Abraham E, Liu G. Identification of TLT2 as an engulfment receptor for apoptotic cells. J Immunol. 2012;188(12):6381-6388.

Tadie JM, Bae HB, Deshane JS, Bell CP, Lazarowski ER, Chaplin DD, Thannickal VJ, Abraham E, Zmijewski JW. Toll-like receptor 4 engagement inhibits adenosine 5'-monophosphate-activated protein kinase activation through a high mobility group box 1 protein-dependent mechanism. Mol Med. 2012;18(1):659-668.

Bae HB, Zmijewski JW, Deshane JS, Zhi D, Thompson LC, Peterson CB, Chaplin DD, Abraham E. Vitronectin inhibits neutrophil apoptosis through activation of integrin-associated signaling pathways. Am J Respir Cell Mol Biol. 2012;46(6):790-796.

Yang S, Banerjee S, de Freitas A, Cui H, Xie N, Abraham E, Liu G. miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling. Am J Physiol Lung Cell Mol Physiol. 2012;302(6):L521-L529.

Davis K, Banerjee S, Friggeri A, Bell C, Abraham E, Zerfaoui M. Poly(ADP-ribosyl)ation of high mobility group box 1 (HMGB1) protein enhances inhibition of efferocytosis. Mol Med. 2012;18(1):359-369.

Yang S, Banerjee S, de Freitas A, Sanders YY, Ding Q, Matalon S, Thannickal VJ, Abraham E, Liu G. Participation of miR-200 in pulmonary fibrosis. Am J Pathol. 2012;180(2):484-493.

Asehnoune K, Roquilly A, Abraham E. Innate immune dysfunction in trauma patients: from pathophysiology to treatment [editorial]. Anesthesiology. 2012;117(2):411-416.

Friggeri A, Banerjee S, Xie N, Cui H, de Freitas A, Zerfaoui M, Dupont H, Abraham E, Liu G. Extracellular histones inhibit efferocytosis. Mol Med. 2012;18(5):825-833.

Banerjee S, de Freitas A, Friggeri A, Zmijewski JW, Liu G, Abraham E. Intracellular HMGB1 negatively regulates efferocytosis. J Immunol. 2011;187(9):4686-4694.

Bae H-B, Zmijewski JW, Deshane JS, Tadie J-M, Chaplin DD, Takashima S, Abraham E. AMP-activated protein kinase enhances the phagocytic ability of macrophages and neutrophils. FASEB J. 2011;25(12):4358-4368.

Deshane J, Zmijewski JW, Luther R, Gaggar A, Deshane R, Lai JF, Xu X, Spell M, Estell K, Weaver CT, Abraham E, Schwiebert LM, Chaplin DD. Free radical-producing myeloid-derived regulatory cells: potent activators and suppressors of lung inflammation and airway hyperresponsiveness. Mucosal Immunol. 2011;4(5):503-518.

Zmijewski JW, Bae H-B, Deshane JS, Peterson CB, Chaplin DD, Abraham E. Inhibition of neutrophil apoptosis by PAI-1. Am J Physiol Lung Cell Mol Physiol. 2011;301(2):L247-254.

Liu G, Yang Y, Yang S, Banerjee S, De Freitas A, Friggeri A, Davis KI, Abraham E. The receptor for urokinase regulates TLR2 mediated inflammatory responses in neutrophils. PLoS ONE. 2011;6(10):e25843.

Zarjou A, Yang S, Abraham E, Agarwal A, Liu G. Identification of a microRNA signature in renal fibrosis: role of miR-21. Am J Physiol Renal Physiol. 2011;301(4):F793-F801.