Edward Abraham, M.D.Wake Forest School of Medicine

Doctor Rating

No Rating Available
Why No Ratings?

Edward Abraham, M.D.


Contact Information

Department: 336-716-4424


Insurance Accepted »

Education & Training

  • B.A., Stanford University, 1974
  • M.D., Stanford University School of Medicine, 1978
  • Internship, UCLA Hosp, 1979
  • Residency, UCLA Hosp, 1981
  • Fellowship, Emergency Medicine, University of California-Los A, 1982
  • Fellowship, Critical Care Medicine, LA County Harbor-UCLA Med Ctr, 1983

Board Certifications

  • American Board of Internal Medicine, Internal Medicine, Critical Care Medicine


  • Am Assn Of Immunologists
  • Shock Society
  • Soc Of Critical Care Medicine
  • Southern Society Of Clinical I
  • Am Coll Of Critical Care Medic
  • Am Coll Of Physicians
  • Am Soc Of Clinical Investigati
  • American Thoracic Society
  • Assn Of American Physicians
  • Assn of Professors of Medicine

NPI Number

  • 1962456715
Edward Abraham, M.D.

Doctor Rating

No Rating Available
Why No Ratings?

Edward Abraham, M.D.

Dean, Dean's Office
Professor, Pulmonary, Critical Care, Allergy, and Immunologic Medicine

Contact Information

Department: 336-716-4424


Recent Publications

Roquilly A, Marret E, Abraham E, Asehnoune K. Pneumonia prevention to decrease mortality in intensive care unit: a systematic review and meta-analysis. Clin Infect Dis. 2015;60(1):64-75.

Roquilly A, Marret E, Abraham E, Asehnoune K. Reply to Hurley [Is selective decontamination of the digestive tract safe?] [reply to letter]. Clin Infect Dis. 2015;60(11):1730-1731.

Jiang S, Park DW, Gao Y, Ravi S, Darley-Usmar V, Abraham E, Zmijewski JW. Participation of proteasome-ubiquitin protein degradation in autophagy and the activation of AMP-activated protein kinase. Cell Signal. 2015;27(6):1186-1197.

Tan Z, Xie N, Cui H, Moellering DR, Abraham E, Thannickal VJ, Liu G. Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism. J Immunol. 2015;194(12):6082-6089.

Feng JY, Liu KT, Abraham E, Chen CY, Tsai PY, Chen YC, Lee YC, Yang KY. Serum estradiol levels predict survival and acute kidney injury in patients with septic shock- a prospective study. PLoS One. 2014;9(6):e97967.

Jiang S, Park DW, Tadie JM, Gregoire M, Deshane J, Pittet JF, Abraham E, Zmijewski JW. Human resistin promotes neutrophil proinflammatory activation and neutrophil extracellular trap formation and increases severity of acute lung injury. J Immunol. 2014;192(10):4795-4803.

Xie N, Cui H, Banerjee S, Tan Z, Salomao R, Fu M, Abraham E, Thannickal VJ, Liu G. miR-27a regulates inflammatory response of macrophages by targeting IL-10. J Immunol. 2014;193(1):327-334.

Cui H, Xie N, Tan Z, Banerjee S, Thannickal VJ, Abraham E, Liu G. The human long noncoding RNA lnc-IL7R regulates the inflammatory response. Eur J Immunol. 2014;44(7):2085-2095.

Park DW, Jiang S, Liu Y, Siegal GP, Inoki K, Abraham E, Zmijewski JW. GSK3beta-dependent inhibition of AMPK potentiates activation of neutrophils and macrophages and enhances severity of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2014;307(10):L735-L745.

Powell BL, Olson D, Morrell RM, Hales TL, High KP, Abraham E. Increasing clinical trials accrual at a Comprehensive Cancer Center [abstract]. Blood. 2014;124(21):1266.

Liu G, Abraham E. MicroRNAs in immune response and macrophage polarization. Arterioscler Thromb Vasc Biol. 2013;33(2):170-177.

Bae HB, Tadie JM, Jiang S, Park DW, Bell CP, Thompson LC, Peterson CB, Thannickal VJ, Abraham E, Zmijewski JW. Vitronectin inhibits efferocytosis through interactions with apoptotic cells as well as with macrophages. J Immunol. 2013;190(5):2273-2281.

Tadie JM, Bae HB, Jiang S, Park DW, Bell CP, Yang H, Pittet JF, Tracey K, Thannickal VJ, Abraham E, Zmijewski JW. HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4. Am J Physiol Lung Cell Mol Physiol. 2013;304(5):L342-349.

Abraham E. The dichotomy of inhibiting nuclear factor kappa-B in pneumonia [commentary]. Crit Care. 2013;17(3):152.

Banerjee S, Xie N, Cui H, Tan Z, Yang S, Icyuz M, Abraham E, Liu G. MicroRNA let-7c regulates macrophage polarization. J Immunol. 2013;190(12):6542-6549.

Yang S, Cui H, Xie N, Icyuz M, Banerjee S, Antony VB, Abraham E, Thannickal VJ, Liu G. miR-145 regulates myofibroblast differentiation and lung fibrosis. FASEB J. 2013;27(6):2382-2391.

Park DW, Jiang S, Tadie JM, Stigler WS, Gao Y, Deshane J, Abraham E, Zmijewski JW. Activation of AMPK enhances neutrophil chemotaxis and bacterial killing. Mol Med. 2013;19():387-398.

Banerjee S, Cui H, Xie N, Tan Z, Yang S, Icyuz M, Thannickal VJ, Abraham E, Liu G. miR-125a-5p regulates differential activation of macrophages and inflammation. J Biol Chem. 2013;288(49):35428-36.

Tadie J-M, Bae H-B, Banerjee S, Zmijewski JW, Abraham E. Differential activation of RAGE by HMGB1 modulates neutrophil-associated NADPH oxidase activity and bacterial killing. Am J Physiol Cell Physiol. 2012;302(1):C249-256.

Lin W-Y, Tiwari HK, Gao G, Zhang K, Arcaroli JJ, Abraham E. Similarity-based multimarker association tests for continuous traits. Ann Hum Genet. 2012;76(3):246-260.

Alberti MO, Roth JC, Ismail M, Tsuruta Y, Abraham E, Pereboeva L, Gerson SL, Curiel DT. Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation. PLoS ONE. 2012;7(5):e37812.

de Freitas A, Banerjee S, Xie N, Cui H, Davis KI, Friggeri A, Fu M, Abraham E, Liu G. Identification of TLT2 as an engulfment receptor for apoptotic cells. J Immunol. 2012;188(12):6381-6388.

Tadie JM, Bae HB, Deshane JS, Bell CP, Lazarowski ER, Chaplin DD, Thannickal VJ, Abraham E, Zmijewski JW. Toll-like receptor 4 engagement inhibits adenosine 5'-monophosphate-activated protein kinase activation through a high mobility group box 1 protein-dependent mechanism. Mol Med. 2012;18(1):659-668.

Bae HB, Zmijewski JW, Deshane JS, Zhi D, Thompson LC, Peterson CB, Chaplin DD, Abraham E. Vitronectin inhibits neutrophil apoptosis through activation of integrin-associated signaling pathways. Am J Respir Cell Mol Biol. 2012;46(6):790-796.

Yang S, Banerjee S, de Freitas A, Cui H, Xie N, Abraham E, Liu G. miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling. Am J Physiol Lung Cell Mol Physiol. 2012;302(6):L521-L529.

Davis K, Banerjee S, Friggeri A, Bell C, Abraham E, Zerfaoui M. Poly(ADP-ribosyl)ation of high mobility group box 1 (HMGB1) protein enhances inhibition of efferocytosis. Mol Med. 2012;18(1):359-369.

Yang S, Banerjee S, de Freitas A, Sanders YY, Ding Q, Matalon S, Thannickal VJ, Abraham E, Liu G. Participation of miR-200 in pulmonary fibrosis. Am J Pathol. 2012;180(2):484-493.

Asehnoune K, Roquilly A, Abraham E. Innate immune dysfunction in trauma patients: from pathophysiology to treatment [editorial]. Anesthesiology. 2012;117(2):411-416.

Friggeri A, Banerjee S, Xie N, Cui H, de Freitas A, Zerfaoui M, Dupont H, Abraham E, Liu G. Extracellular histones inhibit efferocytosis. Mol Med. 2012;18(5):825-833.

Kangelaris KN, Sapru A, Calfee CS, Liu KD, Pawlikowska L, Witte JS, Vittinghoff E, Zhuo H, Auerbach AD, Ziv E, Matthay MA, Abraham E, et al. The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. Chest. 2012;141(5):1160-1169.

Banerjee S, de Freitas A, Friggeri A, Zmijewski JW, Liu G, Abraham E. Intracellular HMGB1 negatively regulates efferocytosis. J Immunol. 2011;187(9):4686-4694.

Bae H-B, Zmijewski JW, Deshane JS, Tadie J-M, Chaplin DD, Takashima S, Abraham E. AMP-activated protein kinase enhances the phagocytic ability of macrophages and neutrophils. FASEB J. 2011;25(12):4358-4368.

Deshane J, Zmijewski JW, Luther R, Gaggar A, Deshane R, Lai JF, Xu X, Spell M, Estell K, Weaver CT, Abraham E, Schwiebert LM, Chaplin DD. Free radical-producing myeloid-derived regulatory cells: potent activators and suppressors of lung inflammation and airway hyperresponsiveness. Mucosal Immunol. 2011;4(5):503-518.

Zmijewski JW, Bae H-B, Deshane JS, Peterson CB, Chaplin DD, Abraham E. Inhibition of neutrophil apoptosis by PAI-1. Am J Physiol Lung Cell Mol Physiol. 2011;301(2):L247-254.

Liu G, Yang Y, Yang S, Banerjee S, De Freitas A, Friggeri A, Davis KI, Abraham E. The receptor for urokinase regulates TLR2 mediated inflammatory responses in neutrophils. PLoS ONE. 2011;6(10):e25843.

Zarjou A, Yang S, Abraham E, Agarwal A, Liu G. Identification of a microRNA signature in renal fibrosis: role of miR-21. Am J Physiol Renal Physiol. 2011;301(4):F793-F801.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Quick Reference

Request an Appointment
New Patients


Existing patients may contact the clinic directly.
Find a Doctor Ways to Give
USNWR 2013-2014Magnet Hospital RecognitionConsumer Choice2014 Best DoctorsJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.