Profile

Sarfaraz Ahmad, Ph.D.Wake Forest School of Medicine

Sarfaraz Ahmad, Ph.D.

Instructor,

Contact Information

Academic: 336-716-9049 | Department: 336-716-9049

Email: sahmad@wakehealth.edu

Additional Languages

Hindi

Education & Training

  • M.S., Aligarh Muslim University J.N. Med-India , 1991
  • Ph.D., Aligarh Muslim University J.N. Med-India , 1996
  • Fellowship, Mercer University-Southern Sch, 2005
  • Fellowship, WFU School of Medicine, 2008
  • Fellowship, WFU School of Medicine, 2011
  • Fellowship, WFU School of Medicine, 2011

Memberships

  • Aha - High Blood Pressure Res.
  • Am Physiological Society
  • American Physiology
  • Oxygen Society
  • Society of Toxicology
  • Toxicology Letters
Sarfaraz Ahmad, Ph.D.

Sarfaraz Ahmad, Ph.D.

Instructor, Surgery, General

Research Interests

cardiac function

Contact Information

Academic: 336-716-9049 | Department: 336-716-9049

Email: sahmad@wakehealth.edu

Recent Publications

Varagic J, Ahmad S, Nagata S, Ferrario CM. ACE2: angiotensin II/angiotensin-(1-7) balance in cardiac and renal injury. Curr Hypertens Rep. 2014;16(3):420.

Ahmad S, Varagic J, Groban L, Dell'italia LJ, Nagata S, Kon ND, Ferrario CM. Angiotensin-(1-12): a chymase-mediated cellular angiotensin II substrate. Curr Hypertens Rep. 2014;16(5):429.

Ferrario CM, Ahmad S, Nagata S, Simington SW, Varagic J, Kon N, Dell'italia LJ. An evolving story of angiotensin-II-forming pathways in rodents and humans. Clin Sci. 2014;126(7-8):461-469.

Moniwa N, Varagic J, Ahmad S, Voncannon JL, Simington SW, Wang H, Groban L, Brosnihan KB, Nagata S, Kato J, Kitamura K, Gomez RA, Lopez ML, Ferrario CM. Hemodynamic and hormonal changes to dual Renin-Angiotensin system inhibition in experimental hypertension. Hypertension. 2013;61(2):417-424.

Varagic J, Ahmad S, VonCannon JL, Moniwa N, Brosnihan KB, Wysocki J, Batlle D, Ferrario CM. Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats. Am J Hypertens. 2013;26(5):583-590.

Ahmad S, Wei CC, Tallaj J, Dell'Italia LJ, Moniwa N, Varagic J, Ferrario CM. Chymase mediates angiotensin-(1-12) metabolism in normal human hearts. J Am Soc Hypertens. 2013;7(2):128-136.

Wang H, Jessup JA, Zhao Z, Da Silva J, Lin M, Macnamara LM, Ahmad S, Chappell MC, Ferrario CM, Groban L. Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats. PLoS One. 2013;8(10):e76992.

Wang H, Zhao Z, Jessup J, Lin M, MacNamara L, Ahmad S, Ferrario C, Groban L. Estrogen replacement downregulates cardiac angiotensin II in an ACE-independent manner in oophorectomized mRen2.Lewis rats [abstract]. Circ Res. 2013;113(4 Suppl):A086.

Moniwa N, Varagic J, Simington SW, Ahmad S, Nagata S, Voncannon JL, Ferrario CM. Primacy of angiotensin converting enzyme in angiotensin-(1-12) metabolism. Am J Physiol Heart Circ Physiol. 2013;305(5):H644-H650.

Moniwa N, Varagic J, Nagata S, Ahmad S, Simington SW, VonCannon JL, Shimamura Y, Hasegawa K, Takizawa H, Ura N, Tanaka S, Furuhashi M, Yoshida H, Miura T, Ferrario CM. Renin independent Ang-(1-12) production in both the systemic and coronary circulation [abstract]. Hypertension. 2013;62(3 Suppl):604.

Nagata S, Varagic J, Simington SW, Ahmad S, VonCannon JL, Wang H, Groban L, Kon ND, Dell'Italia LJ, Ferrario CM. Differential expression of angiotensin-(1-12)/chymase in human atrial tissue [abstract]. Hypertension. 2013;62(3 Suppl):629.

Nagata S, Varagic J, Simington SW, Ahmad S, VonCannon JL, Wang H, Kon ND, Dell'Italia LJ, Ferrario CM, Groban L. Does cardiac ang-(1-12) have a role in sex-specific heart disease? [abstract]. Hypertension. 2013;62(3 Suppl):632.

Moniwa N, Varagic J, Ahmad S, VonCannon JL, Ferrario CM. Restoration of the blood pressure circadian rhythm by direct renin inhibition and blockade of angiotensin II receptors in mRen2.Lewis hypertensive rats. Ther Adv Cardiovasc Dis. 2012;6(1):15-29.

Moniwa N, Varagic J, Ahmad S, Ferrario CM. Effects of combination therapy with valsartan and aliskiren on arterial pressure, cardiac hypertrophy and urinary protein excretion in hypertensive rats [abstract]. FASEB J. 2012;26(Meeting Abstracts):1105.4.

Moniwa N, Wei C-C, Dell'Italia LJ, Ferrario CM, Ahmad S, Varagic J. Chymase-mediated angiotensin II generation from angiotensin-(1-12) in left ventricular tissue of normal and diseased human subjects [abstract]. J Clin Hypertens (Greenwich). 2012;14(Suppl 1):149.

Varagic J, Ahmad S, Voncannon JL, Moniwa N, Simington SW Jr, Brosnihan BK, Gallagher PE, Habibi J, Sowers JR, Ferrario CM. Nebivolol reduces cardiac angiotensin II, associated oxidative stress and fibrosis but not arterial pressure in salt-loaded spontaneously hypertensive rats. J Hypertens. 2012;30(9):1766-1774.

Wei C-C, Chen Y, Powell LC, Zheng J, Shi K, Bradley WE, Powell PC, Ahmad S, Ferrario CM, Dell'Italia LJ. Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss. PLoS One. 2012;7(6):e40110.

Moniwa N, Varagic J, Ahmad S, Ferrario CM. Differential effects of ACE and chymase in the metabolism of exogenous angiotensin-(1-12) in Wistar-Kyoto rats [abstract]. FASEB J. 2012;26(Meeting Abstracts Suppl):1105.3.

Moniwa N, Ahmad S, VonCannon JL, Simington SW, Varagic J, Ferrario CM. Role of angiotensin converting enzyme on the production of angiotensins from angiotensin-(1-12) in normotensive Winstar-kyoto rats and spontaneously hypertensive rats [abstract]. Hypertension. 2012;60(3 Suppl):235.

Varagic J, Ahmad S, Moniwa N, Brosnihan KB, Wysocki J, Batlle D, Ferrario CM. Predominance of angiotensin II type 1 receptor blockade over antiotensin-(1-7) mechanisms in the regulation of blood pressure and renin angiotensin system in mRen.Lewis rats [abstract]. Hypertension. 2012;60(Suppl 3):283.

Simington SW, Moniwa N, Ahmad S, VonCannon JL, Dell'Italia LJ, Varagic J, Ferrario CM. Renin does not participate in the production of plasma ang-(1-12) from angiotensinogen [abstract]. Hypertension. 2012;60(3 Suppl):628.

Ahmad S, Varagic J, Westwood BM, Chappell MC, Ferrario CM. Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes. PLoS ONE. 2011;6(1):e15759.

Varagic J, Ahmad S, Habibi J, Sowers JR, Ferrario CM. Differential regulation of NOS in kidney and heart of SHR fed high salt diet [abstract]. FASEB J. 2011;25(Meeting Abstracts):643.7.

Varagic J, Ahmad S, Moniwa N, Brosnihan KB, Ferrario CM. Olmesartan reduces angiotensin II without affecting ACE activity in kidneys of mRen2.Lewis rats [abstract]. FASEB J. 2011;25(Meeting Abstracts):1b358.

Ahmad S, Simmons T, Varagic J, Moniwa N, Chappell MC, Lively M, Ferrario CM. Localization and metabolism of angiotensin-(1-12) in human atrial tissue [abstract]. Hypertension. 2011;58(5):e50.

Moniwa N, Varagic J, Ahmad S, Ferrario CM. RAS blockade restores circadian rhythm of arterial pressure in a renin-dependent model of experimental hypertension [abstract]. Hypertension. 2011;58(5):e151.

Varagic J, Ahmad S, Gallagher PE, Habibi J, Sowers J, Ferrario CM. Nebivolol reduces cardiac angiotensin II, associated oxidative stress and fibrosis but not arterial pressure in salt-loaded SHR [abstract]. Hypertension. 2011;58(5):e80.

Ahmad S, Simmons T, Varagic J, Moniwa N, Chappell MC, Ferrario CM. Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue. PLoS ONE. 2011;6(12):e28501.

Varagic J, Ahmad S, Brosnihan KB, Groban L, Chappell MC, Tallant EA, Gallagher PE, Ferrario CM. Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction. Ther Adv Cardiovasc Dis. 2010;4(1):17-25.

Ahmad S, Varagic J, Westwood B, Chappell MC, Strawn WB, Simmons T, Ferrario CM. Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue [abstract]. FASEB J. 2010;24(1 Meeting Abstracts):605.4.

Ferrario CM, Ahmad S, Joyner J, Varagic J. Advances in the renin angiotensin system focus on angiotensin-converting enzyme 2 and angiotensin-(1-7). Adv Pharmacol. 2010;59():197-233.

Varagic J, Ahmad S, Brosnihan KB, Habibi J, Sowers JR, Ferrario CM. The effects of nebivolol on salt-induced renal injury [abstract]. Hypertension. 2010;56(5):e155.

Varagic J, Ahmad S, Brosnihan KB, Habibi J, Tilmon RD, Sowers JR, Ferrario CM. Salt-induced renal injury in spontaneously hypertensive rats: effects of nebivolol. Am J Nephrol. 2010;32(6):557-566.

Ahmad S, Varagic J, Westwood B, Chappell MC, Ferrario CM. Uptake of novel peptide angiotensin-(1-12) by cardiac myocytes [abstract]. Hypertension. 2009;54(4):e111.

Varagic J, Ahmad S, Brosnihan KB, Ferrario CM. Spironolactone and angiotensin-(1-7) in salt-induced cardiac injury [abstract]. Hypertension. 2009;54(4):e26.



All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Instructor, Surgery, General

Sarfaraz Ahmad, Ph.D.

Sarfaraz Ahmad, Ph.D.

Instructor, Surgery, General

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