Profile

Robert J. Applegate, M.D.Wake Forest Baptist Health

Doctor Rating

4.7 out of 5

130 Ratings
12 Comments

Robert J. Applegate, M.D.

Professor,

Clinical Interests

Angioplasty, Cardiac Catheterization, Cardiology (clinical), Cardiology (interventional)

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New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-6674
Department: 336-716-7631

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Education & Training

  • B.A., University of California-Los Angeles, 1973
  • B.S., San Jose State University, 1976
  • M.D., University of Virginia School of Medicine, 1980
  • Internship, Medicine, Oregon Health Science Univ Sch, 1981
  • Residency, Medicine, Oregon Health Science Univ Sch, 1983
  • Fellowship, University of Texas Health Sci, 1984
  • Fellowship, University of Texas Health Sci, 1986

Board Certifications

  • American Board of Internal Medicine, Internal Medicine
  • American Board of Internal Medicine, Internal Medicine, Cardiovascular Disease
  • American Board of Internal Medicine, Internal Medicine, Interventional Cardiology

Memberships

  • American College of Cardiology
  • Am Federation Of Clinical Rese
  • Aha - Council On Cardiology
  • Forsyth-Davie-Stokes Medical S

NPI Number

  • 1740265032
Robert J. Applegate, M.D.

Doctor Rating

4.7 out of 5

130 Ratings
12 Comments

Robert J. Applegate, M.D.

Professor, Cardiology

Research Interests

atherosclerosis/thrombosis, cardiac function, drugs/therapeutic agents pharm, health services, research/outc, medical technology/devices, vascular diseases

Contact Information

Request An Appointment

Academic: 336-716-2718 | Department: 336-716-7631

Media Medical Expert »

Related Links

Recent Publications

Applegate RJ. Retrograde percutaneous coronary intervention for chronic total occlusion: going backward to go forward [editorial comment]. J Am Coll Cardiol. 2015;65(22):2401-2403.

Gilbert ON, Hermann DD, Alvarez L, Deutsch C, Aldrich A, Sacrinty M, Pu M, Stacey R, Applegate R, Gandhi S, Zhao D. Transcatheter aortic valve replacement customization based on paravalvular aortic regurgitation location [abstract]. J Am Coll Cardiol. 2015;65(10 Suppl):A1791.

Applegate RJ. Radial access for primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: time for a paradigm shift? [editorial comment]. J Am Coll Cardiol. 2014;63(10):973-975.

Kern MJ, Applegate RJ, Bell M, Brilakis ES, Butman SM, Bach RG, Kaul P, Klein LW, Krucoff MW, Moore JA, Price MJ, Rao SV, Stone GW, Uretsky BF. Conversations in cardiology: bridging antiplatelet therapy before surgery. Catheter Cardiovasc Interv. 2014;83(5):748-752.

Lee MS, Applegate B, Rao SV, Kirtane A, Seto A, Stone GW. Minimizing femoral artery access complications during percutaneous coronary intervention: a comprehensive review. Catheter Cardiovasc Interv. 2014;84(1):62-69.

Waksman R, Kirtane AJ, Torguson R, Cohen DJ, Ryan T, Raber L, Applegate R, Waxman S, Gordon P, Kaneshige K, Leon MB. Correlates and outcomes of late and very late drug-eluting stent thrombosis: results from DESERT (International Drug-Eluting Stent Event Registry of Thrombosis). JACC Cardiovasc Interv. 2014;7(10):1093-1102.

Anderson J, Sacrinty M, Turner S, Gandhi S, Santos R, Kutcher M, Little W, Applegate R. Gender differences in vascular complications associated with transfemoral and transradial cardiac catheterization and PCI: a single-center experience [abstract]. J Am Coll Cardiol. 2013;61(10 Suppl):E77.

Applegate RJ, Sacrinty M, Gandhi S, Kutcher M, Santos R, Little W. Cost effectiveness of Everolimus-eluting compared to propensity score matched bare metal stenting: an analysis of a selected stent strategy [abstract]. J Am Coll Cardiol. 2013;61(10 Suppl):E1505.

Butler M, Sacrinty M, Little W, Applegate R, Kutcher M, Santos R, Gandhi S. Peak troponin I greater than 5 times the 99th percentile after PCI does not define a high-risk group [abstract]. J Am Coll Cardiol. 2013;61(10 Suppl):E1879.

Applegate RJ. The radial approach for STEMI: could this become the new standard of care? [magazine article]. Cardiac Intervent Today. 2013;May/June():51-55.

Forrest JK, Lansky AJ, Meller SM, Hou L, Sood P, Applegate RJ, Wang JC, Skelding KA, Shah A, Kereiakes DJ, Sudhir K, Cristea E, Yaqub M, Stone GW. Evaluation of XIENCE V everolimus-eluting and Taxus Express2 paclitaxel-eluting coronary stents in patients with jailed side branches from the SPIRIT IV trial at 2 years. Am J Cardiol. 2013;111(11):1580-1586.

D'Ascenzo F, Bollati M, Clementi F, Castagno D, Lagerqvist B, de la Torre Hernandez JM, ten Berg JM, Brodie BR, Urban P, Jensen LO, Sardi G, Waksman R, Lasala JM, Schulz S, Stone GW, Airoldi F, Colombo A, Lemesle G, Applegate RJ,. Incidence and predictors of coronary stent thrombosis: evidence from an international collaborative meta-analysis including 30 studies, 221,066 patients, and 4276 thromboses. Int J Cardiol. 2013;167(2):575-584.

Kern M, Applegate R, Bach RG, Bailey SR, Bashore TM, Bass TA, Bell M, de Bruyne B, Garratt KN, Jeremias A, Kereiakes DJ, Klein LW, Krucoff MW, Mintz GS, Morrison D, Ohman EM, Pichard A, Rosenfield K, Samady H, Stone GW,. Conversation in cardiology: should FFR and IVUS be counted as PCI? [editorial]. Catheter Cardiovasc Interv. 2013;82(1):110-115.

Whitbeck MG, Applegate RJ. Second generation drug-eluting stents: a review of the everolimus-eluting platform. Clin Med Insights Cardiol. 2013;7():115-126.

Applegate R, Sacrinty M, Schafer P, Smith J, Gandhi S, Kutcher M, Santos R, Cecile A, Little W. Cost effectiveness of radial access for diagnostic cardiac catheterization and coronary intervention. Catheter Cardiovasc Interv. 2013;82(4):E375-E384.

Amin AP, House JA, Safley DM, Chhatriwalla AK, Giersiefen H, Bremer A, Hamon M, Baklanov DV, Aluko A, Wohns D, Mathias DW, Applegate RA, Cohen DJ, Marso SP. Costs of transradial percutaneous coronary intervention. J Am Coll Cardiol Intv. 2013;6(8):827-834.

Waksman R, Torguson R, Kaneshige K, Kirtane A, Ryan T, Applegate R, Waxman S, Cohen D, Gordon P. Who is at risk to develop late drug-eluting stent thrombosis while on dual antiplatelet therapy? A subset analysis from the drug eluting stent event registry of thrombosis (DESERT) [abstract]. Eur Heart J. 2013;34(Suppl 1):551-552.

Douglas CJ, Applegate RJ. Minimizing complications following stent implantation: outcomes and follow-up. Interv Cardiol. 2013;5(3):301-317.

Freilich MI, Gossman DE, Applegate RJ, Werns SW, Gips SJ, Turi ZG. The 'bladder sign'--an important early marker of retroperitoneal hemorrhage. Catheter Cardiovasc Interv. 2012;79(1):158-165.

Noureddine ND, Applegate RJ. Drug-eluting stents versus bare metal stents in ST elevation myocardial infarction: from evidence to practice. Minerva Cardioangiol. 2012;60(1):1-9.

Schafer P, Sacrinty MT, Smith JW, Little W, Gandhi S, Kutcher M, Santos R, Smith T, Cecile AC, Applegate R. Cost-effectiveness analysis of propensity matched radial and femoral cardiac catheterization and coronary intervention [abstract]. J Am Coll Cardiol. 2012;59(13 Suppl):E72.

Hermiller JB, Sudhir K, Applegate RJ, Rizvi A, Wang J, Gordon PC, Yaqub M, Cao S, Ferguson JM, Smith RS Jr, Sood P, Stone GW. Impact of age on clinical outcomes after everolimus-eluting and paclitaxel-eluting stent implantation: pooled analysis from the SPIRIT III and SPIRIT IV clinical trials. EuroIntervention. 2012;8(1):87-93.

Applegate RJ. Vascular closure device failure: we are getting better but not there yet [editorial comment]. JACC Cardiovasc Interv. 2012;5(8):845-847.

Lansky AJ, Brar SS, Yaqub M, Sood P, Applegate RJ, Lazar D, Jankovic I, Hermiller JB, Koo K, Sudhir K, Stone GW. Impact of routine angiographic follow-up after percutaneous coronary intervention with drug-eluting stents in the SPIRIT III randomized trial at three years. Am J Cardiol. 2012;110(1):21-29.

Turner S, Sacrinty M, Manogue M, Little W, Gandhi S, Kutcher M, Santos R, Applegate R. Transitioning to the radial artery as the preferred access site for cardiac catheterization: an academic medical center experience. Catheter Cardiovasc Interv. 2012;80(2):247-257.

Jollis JG, Al-Khalidi HR, Monk L, Roettig ML, Garvey JL, Aluko AO, Wilson BH, Applegate RJ, Mears G, Corbett CC, Granger CB. Expansion of a regional ST-segment-elevation myocardial infarction system to an entire state. Circulation. 2012;126(2):189-195.

Butler MM, Applegate RJ. Complex PCI in an elderly diabetic patient with advanced chronic kidney disease [clinical case update]. Contrast-Induced Nephropathy Education. 2012;August():1-6.

Waksman R, Torguson R, Kaneshige K, Kirtane A, Ryan T, Raber L, Applegate R, Waxman S, Cohen D, Gordon P. Angiographic correlates of late and very late drug-eluting stent thrombosis: findings from the international multicenter Drug Eluting Stent Event Registry of Thrombosis (DESERT) [abstract]. Eur Heart J. 2012;33(Suppl 1):389.

Applegate R, Sacrinty M, Allem J, Gandhi S, Kutcher M, Santos R, Smith T, Little W. Contrast use and acute kidney injury in contemporary clinical practice [abstract]. J Am Coll Cardiol. 2012;60(17 Suppl B):B39-B40.

Applegate R, Sacrinty M, Gandhi S, Kutcher M, Santos R, Smith T, Little W. Cost effectiveness of Everolimus-eluting stents compared to first generation drug-eluting stents in contemporary clinical practice [abstract]. J Am Coll Cardiol. 2012;60(17 Suppl B):B185.

Ohara T, Anzai T, Yasuda S, Ogawa H, Applegate R, Little W. Diastolic function at rest determines the prognosis of myocardial infarction [abstract]. J Card Fail. 2012;18(10 Suppl 1):S190.

Waksman R, Torguson R, Kaneshige K, Kirtane A, Ryan T, Raber L, Applegate R, Waxman S, Cohen D, Gordon P. Drug-eluting stent event registry of thrombosis (DESERT): the International Drug-Eluting Stent Thrombosis Registry, angiographic assessment [abstract]. J Am Coll Cardiol. 2012;60(17 Suppl):B180-B181.

Pervaiz MH, Sood P, Sudhir K, Hermiller JB, Hou L, Hattori K, Su X, Cao S, Wang J, Applegate RJ, Kereiakes DJ, Yaqub M, Stone GW, Cutlip DE. Periprocedural myocardial infarction in a randomized trial of everolimus-eluting and Paclitaxel-eluting coronary stents: frequency and impact on mortality according to historic versus universal definitions. Circ Cardiovasc Interv. 2012;5(2):150-156.

Holland BH, Applegate RJ. Femoral vascular access - approaches and available devices. Interv Cardiol Rev. 2012;7(2):108-114.

Humphrey HL, Applegate RJ. Risk scoring systems for PCI: does one size fit all? [commentary]. J Invasive Cardiol. 2011;23(2):70-71.

Applegate RJ, Yaqub M, Hermiller JB, Sood P, Yu S, Doostzadeh J, Williams JE, Farhat N, Caputo R, Lansky AJ, et al. Long-term (three-year) safety and efficacy of everolimus-eluting stents compared to paclitaxel-eluting stents (from the SPIRIT III Trial). Am J Cardiol. 2011;107(6):833-840.

Applegate RJ. Toward better stratification of patients with left main disease value of clinical and angiographic-derived risk scores [editorial comment]. JACC Cardiovasc Interv. 2011;4(3):298-299.

Applegate RJ. Optimal therapy for ST-segment elevation myocardial infarction: the role of residual thrombus [editorial comment]. J Am Coll Cardiol. 2011;57(19):1874-1876.

Ng VG, Lansky AJ, Hermiller JB, Farhat N, Applegate RJ, Yaqub M, Sood P, Su X, Simonton CA, Sudhir K, et al. Three-year results of safety and efficacy of the everolimus-eluting coronary stent in women (from the SPIRIT III randomized clinical trial). Am J Cardiol. 2011;107(6):841-848.

Stone GW, Rizvi A, Sudhir K, Newman W, Applegate RJ, Cannon LA, Maddux JT, Cutlip DE, Simonton CA, Sood P, et al. Randomized comparison of everolimus- and paclitaxel-eluting stents: 2-year follow-up from the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) IV trial. J Am Coll Cardiol. 2011;58(1):19-25.

Dauerman HL, Rao SV, Resnic FS, Applegate RJ. Bleeding avoidance strategies: consensus and controversy. J Am Coll Cardiol. 2011;58(1):1-10.

Schafer PE, Sacrinty MT, Cohen DJ, Kutcher MA, Gandhi SK, Santos RM, Little WC, Applegate RJ. Cost-effectiveness of drug-eluting stents versus bare metal stents in clinical practice. Circ Cardiovasc Qual Outcomes. 2011;4(4):408-415.

Manogue MR, Sacrinty MT, Little WC, Gandhi SK, Kutcher MA, Santos RM, Turner SJ, Applegate RJ. Bleeding avoidance strategy: transition from femoral to radial artery as the preferred access for cardiac procedures. The Wake Forest academic medical center experience [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl 1):E1057.

Schafer P, Sacrinty MT, Kutcher MA, Santos RM, Gandhi SK, Little WC, Applegate RJ. Cost effectiveness of drug-eluting stents versus bare metal stents in clinical practice: effect of stent length and diameter [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl 1):E1184.

Turner S, Sacrinty MT, Little WC, Gandhi SK, Kutcher MA, Santos RM, Manogue MR, Applegate RJ. Cath lab utilization during transition to the radial artery as preferred access: the Wake Forest academic medical center experience [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl):E1269.

Hermiller JB, Nikolsky E, Lansky AJ, Applegate RJ, Sanz M, Yaqub M, Sood P, Cao S, Sudhir K, Stone GW. Clinical and angiographic outcomes of elderly patients treated with everolimus-eluting versus paclitaxel-eluting stents: three-year results from the SPIRIT III randomised trial. EuroIntervention. 2011;7(3):307-313.

Applegate RJ. Long-term impact of periprocedural bleeding: when does it end? [editorial comment]. J Am Coll Cardiol. 2011;58(17):1757-1759.

Schafer PE, Sacrinty MT, Little WC, Gandhi SK, Kutcher MA, Santos RM, Cecile AC, Applegate RJ. Resource utilization for propensity matched radial and femoral catheterization and intervention [abstract]. J Am Coll Cardiol. 2011;58(20 Suppl B):B146-B147.

Stone GW, Sood P, Applegate RJ, Yaqub M, Hermiller JB, Newman W, Sanz M, Cao S, Bezenek S, Williams JE, Lansky A, Cutlip DE, Sudhir K. Comparison of everolimus-eluting and paclitaxel-eluting stents: first report of the five-year clinical outcomes from the SPIRIT III Trial [abstract]. J Am Coll Cardiol. 2011;58(20 Suppl B):B9.

Applegate RJ, Hermiller JB, Gordon PC, Yaqub M, Sood P, Su X, Cao S, Sudhir K, Stone GW. Predictors of early and late outcomes after everolimus and paclitaxel-eluting coronary stents. EuroIntervention. 2011;7(9):1030-1042.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Cardiology

Clinical Interests

Angioplasty, Cardiac Catheterization, Cardiology (clinical), Cardiology (interventional)
Robert J. Applegate, M.D.

Robert J. Applegate, M.D.

Professor, Cardiology

Request An Appointment

Doctor Rating

4.7 out of 5

Robert J. Applegate, M.D.130 Ratings
12 Comments

Doctor Ratings

The overall Patient Rating score is the average of responses to the nine questions listed below. The questions are from the Press Ganey Patient Satisfaction Survey. Responses are measured on a 1 to 5 scale, where 1 represents "very poor" and 5 represents "very good."
Press Ganey Patient Satisfaction Survey

CP concern for questions/worries
4.6
CP efforts to include in decisions
4.7
CP explanations of prob/condition
4.7
CP spoke using clear language
4.7
Friendliness/courtesy of CP
4.8
Likelihood of recommending CP
4.8
Patients' confidence in CP
4.8
Time CP spent with patient
4.4
Wait time at clinic
4.5



Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.

4/30/2015

He is a great doctor and a friendly person and I would recommend him to anyone.

4/29/2015

I have great faith in *Dr. Applegate. He has been my surgeon, heart doctor and advisor for many years.

2/18/2015

Always a good experience with this doctor.

2/15/2015

my mother would keep Dr. Applegate talking with her all day if he could

2/13/2015

Good.

1/29/2015

I have recommend *Dr. Applegate to my friends.

1/28/2015

All was very good.

1/9/2015

Super help and care.

1/9/2015

Very nice.

11/26/2014

Dr. Applegate has always showed concern for me and answered any questions I asked

10/1/2014

good

9/19/2014

Good.

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