Sarah L. Berga, M.D.Wake Forest School of Medicine

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Sarah L. Berga, M.D.


Clinical Interests

Infertility, Anovulation, Amenorrhea, Complex Hormonal Conditions, Hyperprolactinemia, Gonadal Dysgenesis, Stress-induced Anovulation

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-6476
Department: 336-716-4594


Insurance Accepted »

Education & Training

  • B.A., University of Virginia, 1976
  • M.D., University of Virginia, 1980
  • Residency, Obstetrics & Gynecology, Massachusetts Gen Hosp, 1984
  • Fellowship, Obstetrics & Gynecology, University of California Sch o, 1986

Board Certifications

  • American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
  • American Board of Obstetrics and Gynecology, Reproductive Endocrinology

NPI Number

  • 1124054218
Sarah L. Berga, M.D.

Doctor Rating

No Rating Available
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Sarah L. Berga, M.D.

Chair, Obstetrics & Gynecology
Professor, Obstetrics & Gynecology
Office of Women in Medicine and Science

Research Interests

Amenorrhea; Postmenopause; Hypothalamic Diseases; Cognition; Estradiol
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Contact Information

Academic: 336-716-4594 | Department: 336-716-4594


Recent Publications

Carotid artery distensibility and hormone therapy and menopause: the Los Angeles Atherosclerosis Study. Shufelt C, Elboudwarej O, Johnson BD, Mehta P, Bittner V, Braunstein G, Berga S, Stanczyk F, Dwyer K, Merz CN.. Menopause. 2016;23(2):150-157.

Persistent hypogonadotropic hypogonadism in men after severe traumatic brain injury: temporal hormone profiles and outcome prediction. Barton DJ, Kumar RG, McCullough EH, Galang G, Arenth PM, Berga SL, Wagner AK.. J Head Trauma Rehabil. 2016;31(4):277-287.

Longitudinal sex and stress hormone profiles among reproductive age and post-menopausal women after severe TBI: a case series analysis. Ranganathan P, Kumar RG, Davis K, McCullough EH, Berga SL, Wagner AK.. Brain Inj. 2016;():.

Social determinants of infertility: beyond the obvious [editorial]. Berga SL.. Fertil Steril. 2016;105(6):1459-1460.

Strategies and methods to study female-specific cardiovascular health and disease: a guide for clinical scientists. Ouyang P, Wenger NK, Taylor D, Rich-Edwards JW, Steiner M, Shaw LJ, Berga SL, Miller VM, Merz NB.. Biol Sex Differ. 2016;7():19.

Endometrial stromal decidualization responds reversibly to hormone stimulation and withdrawal. Yu J, Berga SL, Johnston-MacAnanny E, Sidell N, Bagchi IC, Bagchi MK, Taylor RN.. Endocrinology. 2016;157(6):2432-2446.

IL-1 beta disrupts morphological and biochemical differentiation of human endometrial stromal cells: potential role in infertility [abstract]. Yu J, Berga SL, Yook G, Pan JC, Andrade AA, Johnston-MacAnanny EB, Taylor RN.. Reprod Sci. 2016;23(Suppl 1):247A-248A.

Transfer of IVF-contaminated blastocysts with removal of the zona pellucida resulted in live births. Shu Y, Prokai D, Berga S, Taylor R, Johnston-MacAnanny E.. J Assist Reprod Genet. 2016;():.

Variable neuroendocrine-immune dysfunction in individuals with unfavorable outcome after severe traumatic brain injury. Santarsieri M, Kumar RG, Kochanek PM, Berga S, Wagner AK.. Brain Behav Immun. 2015;45():15-27.

Human endometrial stromal cell connexin (Cx)43 responds reversibly to hormone stimulation and withdrawal and regulates markers of angiogenesis and Mesenchymal-Epithelial Transition (MET) [abstract]. Yu J, Berga SL, Johnston-MacAnanny EB, Huang L, Sidell N, Bagchi IC, Bagchi MK, Taylor RN.. Reprod Sci. 2015;22(Suppl 1):81A.

Patterns of change in cognitive function with anastrozole therapy. Bender CM, Merriman JD, Gentry AL, Ahrendt GM, Berga SL, Brufsky AM, Casillo FE, Dailey MM, Erickson KI, Kratofil FM, McAuliffe PF, Rosenzweig MQ, Ryan CM, Sereika SM.. Cancer. 2015;121(15):2627-2636.

Multiple aromatization mechanisms influence mortality and CNS secondary injury profiles after severe TBI [abstract]. Wagner A, Kumar R, Conley Y, Kochanek P, Berga S.. J Neurotrauma. 2015;32(12):A92.

Serum tumor necrosis factor-alpha association with mortality six months after TBI: mechanistic relationships with estradiol [abstract]. Wagner A, Kumar R, Ritter A, Kochanek P, Berga S.. J Neurotrauma. 2015;32(12):A92-A93.

Donor sperm intrauterine inseminations (IUI) in same sex couples or single mothers by choice: how much sperm is enough to achieve pregnancy? [abstract]. Prokai D, Shu Y, Maisel L, Berga SL, Taylor RN, Johnston-MacAnanny EB.. Fertil Steril. 2015;104(3 Suppl):E112.

Cerebrospinal fluid cortisol and progesterone profiles and outcomes prognostication after severe traumatic brain injury. Santarsieri M, Niyonkuru C, McCullough EH, Dobos JA, Dixon CE, Berga SL, Wagner AK.. J Neurotrauma. 2014;31(8):699-712.

Are changes in reproductive hormone levels related to changes in cognitive function in women with breast cancer? [abstract]. Bender C, Sereika S, Ryan C, Berga S.. Nurs Res. 2014;63(2):E58.

Validating the need for uniform information on reproductive history for women in clinical cardiovascular studies and databases [abstract]. Steiner M, Miller V, Garovic V, Rich-Edwards J, Mallampalli M, Merz CNB, Berga S, Reckelhoff J, Taylor D, Wenger N, Ouyang P.. J Womens Health. 2014;23(4):14.

Gap junction protein connexin 43 is necessary and sufficient for pro-implantation phenotype in human endometrial stromal cells [abstract]. Yu J, Berga SL, Yalcinkaya T, Huang, L, Bagchi IC, Bagchi MK, Taylor RN.. Reprod Sci. 2014;21(3 Suppl):413A-414A.

Ovarian hormones modify cell cycle dynamics, apoptosis and telomere length in primary human endometrial stromal cells [abstract]. Yu J, Berga SL, Salinas A, Johnston-MacAnanny E, Taylor RN.. Reprod Sci. 2014;21(3 Suppl):414A.

Gap junction blockade induces apoptosis in human endometrial stromal cells. Yu J, Berga SL, Zou W, Sun HY, Johnston-MacAnanny E, Yalcinkaya T, Sidell N, Bagchi IC, Bagchi MK, Taylor RN.. Mol Reprod Dev. 2014;81(7):666-675.

Ospemifene improved the severity of vulvar and vaginal atrophy symptoms in postmenopausal women in phase 3 randomized, placebo-controlled trials [abstract]. Constantine GD, Kagan R, Berga S, Graham S, Archer DF.. Menopause. 2014;21(12):1332.

Maternal recall of hypertensive disorders in pregnancy: a systematic review. Stuart JJ, Bairey Merz CN, Berga SL, Miller VM, Ouyang P, Shufelt CL, Steiner M, Wenger NK, Rich-Edwards JW.. J Womens Health. 2013;22(1):37-47.

Neuroendocrine recovery initiated by cognitive behavioral therapy in women with functional hypothalamic amenorrhea: a randomized, controlled trial. Michopoulos V, Mancini F, Loucks TL, Berga SL.. Fertil Steril. 2013;99(7):2084-2091.

A statement on abortion by 100 professors of obstetrics: 40 years later. Archer DF, Autry A, Barbieri RL, Berek JS, Berga SL, Bernstein IM, Brodman M, Brown H, Buekens P, Bulun SE, Burkman RT, Campbell WA, Carson LF, Caughey AB, Chaudhuri G, Chelmow D, Chervenak F, Clarke-Pearson DL, et al.. Am J Obstet Gynecol. 2013;88(4):568-576.

Profile of ospemifene in the breast. Berga SL.. Reprod Sci. 2013;20(10):1130-1136.

Impact of aromatase genetic variation on hormone levels and global outcome after severe TBI. Garringer JA, Niyonkuru C, McCullough EH, Loucks T, Dixon CE, Conley YP, Berga S, Wagner AK.. J Neurotrauma. 2013;30(16):1415-1425.

CRH receptor antagonism reverses the effect of social subordination upon central GABAA receptor binding in estradiol-treated ovariectomized female rhesus monkeys. Michopoulos V, Embree M, Reding K, Sanchez MM, Toufexis D, Votaw JR, Voll RJ, Goodman MM, Rivier J, Wilson ME, Berga SL.. Neuroscience. 2013;250():300-308.

Does lifetime exposure to hormones predict pretreatment cognitive function in women before adjuvant therapy for breast cancer?. Bender CM, Sereika SM, Ryan CM, Brufsky AM, Puhalla S, Berga SL.. Menopause. 2013;20(9):922-929.

Estradiol and inflammatory cytokines induce neuroangiogenic responses in endometriosis stromal cells [abstract]. Francisco AMC, Yu J, Yalcinkaya T, Johnston-MacAnanny EB, Sidell N, Berga SL, Taylor RN.. Reprod Sci. 2013;20(3 Suppl):149A.

Assessing the pulsatility of luteinizing hormone in female vervet monkeys (Chlorocebus aethiops sabaeus). Stephens SM, Pau FK, Yalcinkaya TM, May MC, Berga SL, Post MD, Appt SE, Polotsky AJ.. Comp Med. 2013;63(5):432-438.

Does PCOS have developmental origins?. Franks S, Berga SL.. Fertil Steril. 2012;97(1):2-6.

Neuroendocrine control of ovulation. Berga S, Naftolin F.. Gynecol Endocrinol. 2012;28(Suppl 1):9-13.

Short fetal leukocyte telomere length and preterm prelabor rupture of the membranes. Menon R, Yu J, Basanta-Henry P, Brou L, Berga SL, Fortunato SJ, Taylor RN.. PLoS ONE. 2012;7(2):e31136.

Metabolic and reproductive consequences of the serotonin transporter promoter polymorphism (5-HTTLPR) in adult female rhesus monkeys (Macaca mulatta) [abstract]. Hoffman JB, Kaplan JR, Kinkead B, Berga SL, Wilson ME.. Endocrine. 2007;31(2):202-211.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Obstetrics & Gynecology

Clinical Interests

Infertility, Anovulation, Amenorrhea, Complex Hormonal Conditions, Hyperprolactinemia, Gonadal Dysgenesis, Stress-induced Anovulation
Sarah L. Berga, M.D.
CP concern for questions/worries
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CP spoke using clear language
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Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.


She always giving me a quality care and she is a wonderful person.


Dr. Berga is an amazing doctor that is incredibly thorough in her diagnosis. I would recommend her to anyone seeking a doctor!


Wonderful *Dr. Berga.


Outstanding care by an outstanding MD.

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