Colin Edward Bishop, Ph.D.Wake Forest School of Medicine

Colin Edward Bishop, Ph.D.


Contact Information

Academic: 336-713-7273 | Department: 336-716-2011


Additional Languages

Dutch, French

Education & Training

  • B.Sc., University of Wales-United Kingdom, 1972
  • M.Sc., Brunel University, 1978
  • Ph.D., London Hospital Medical Coll-United Kingdom, 1979
  • Fellowship, Allergy & Immunology, London Hospital Medical Coll-U, 1977
  • Fellowship, London Hospital Medical Coll-U, 1981


  • Am Assn Of Advancement Of Scie
  • Am Soc of Human Genetics
Colin Edward Bishop, Ph.D.

Colin Edward Bishop, Ph.D.

Professor, Institute for Regenerative Medicine
Center for Diabetes Research
Pediatrics - Medical Genetics

Research Interests

biotechnology, cell growth, differentiation,d, engineering/bioengineering, genetics/genome, growth & development, infectious diseases, molecular biology/molecular me

Contact Information

Academic: 336-713-7273 | Department: 336-716-2011


Recent Publications

Pan C, Jia W, Lu B, Bishop CE. Expression of TAT recombinant Oct4, Sox2, Lin28, and Nanog proteins from baculovirus-infected Sf9 insect cells. Gene. 2015;556(2):245-248.

Guimaraes-Souza NK, Yamaleyeva LM, Lu B, Ramos AC, Bishop CE, Andersson KE. Superoxide overproduction and kidney fibrosis: a new animal model. Einstein (Sao Paulo). 2015;13(1):79-88.

Skardal A, Devarasetty M, Kang HW, Mead I, Bishop C, Shupe T, Lee SJ, Jackson J, Yoo J, Soker S, Atala A. A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs. Acta Biomater. 2015;25():24-34.

Zani A, Cananzi M, Fascetti-Leon F, Lauriti G, Smith VV, Bollini S, Ghionzoli M, D'Arrigo A, Pozzobon M, Piccoli M, Hicks A, Wells J, Siow B, Sebire NJ, Bishop C, Leon A, Atala A, Lythgoe MF, Pierro A, Eaton S, De Coppi P. Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism. Gut. 2014;63(2):300-309.

Moghaddassi S, Eyestone W, Bishop CE. TALEN-mediated modification of the bovine genome for large-scale production of human serum albumin. PLoS One. 2014;9(2):e89631.

Chang YRR, Mead I, Pendergraft S, Wagoner A, Bishop C. Differentiating induced pluripotent stem cells into cerebral organoids [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S134.

Lorenzetti D, Poirier C, Zhao M, Overbeek PA, Harrison W, Bishop CE. A transgenic insertion on mouse chromosome 17 inactivates a novel immunoglobulin superfamily gene potentially involved in sperm-egg fusion. Mamm Genome. 2014;25(3-4):141-148.

Skardal A, Mead I, Devarasetty M, Kang H, Shupe T, Lee S, Jackson JD, Bishop CE, Yoo JJ, Soker S, Atala A. Integration of 3-D organoid bioprinting and microfluidic device technology for functional primary cell-based liver-on-a-chip operation [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S43.

Campeau L, Hicks A, Burmeister D, Bishop C, Andersson KE. Lack of nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2)- consequences for mouse bladder development and function [abstract]. Neurourol Urodyn. 2013;32(2):130.

Beck TF, Shchelochkov OA, Yu Z, Kim BJ, Hernandez-Garcia A, Zaveri HP, Bishop C, Overbeek PA, Stockton DW, Justice MJ, Scott DA. Novel Frem1-related mouse phenotypes and evidence of genetic interactions with Gata4 and Slit3. PLoS One. 2013;8(3):e58830.

Hicks AN, Campeau L, Burmeister D, Bishop CE, Andersson KE. Lack of nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2): consequences for mouse bladder development and function. Neurourol Urodyn. 2013;32(8):1130-1136.

Jiao Y, Bishop CE, Lu B. Mex3c regulates insulin-like growth factor 1 (IGF1) expression and promotes postnatal growth. Mol Biol Cell. 2012;23(8):1404-1413.

George SK, Jiao Y, Bishop CE, Lu B. Oxidative stress is involved in age-dependent spermatogenic damage of Immp2l mutant mice. Free Radic Biol Med. 2012;52(11-12):2223-2233.

Hicks AN, Lorenzetti D, Gilley J, Lu B, Andersson KE, Miligan C, Overbeek PA, Oppenheim R, Bishop CE. Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo. PLoS One. 2012;7(10):e47869.

Jiao Y, George SK, Zhao Q, Hulver MW, Hutson SM, Bishop CE, Lu B. Mex3c mutation reduces adiposity and increases energy expenditure. Mol Cell Biol. 2012;32(21):4350-4362.

George SK, Jiao Y, Bishop CE, Lu B. Mitochondrial peptidase IMMP2L mutation causes early onset of age-associated disorders and impairs adult stem cell self-renewal. Aging Cell. 2011;10(4):584-594.

Moorefield EC, McKee EE, Solchaga L, Orlando G, Yoo JJ, Walker S, Furth ME, Bishop CE. Cloned, CD117 selected human amniotic fluid stem cells are capable of modulating the immune response. PLoS ONE. 2011;6(10):e26535.

Hicks A, Lorenzetti D, Lu B, Andersson K-E, Overbeek P, Oppenheim R, Bishop C. Nervous system defects in the novel bloated bladder mouse mutant (BLAD) [abstract]. Soc Neurosci Abstr. 2011;2011(Neuroscience Meeting Planner):33.15.

Soler R, Fullhase C [Fuellhase C], Lu B, Bishop CE, Andersson K-E. Bladder dysfunction in a new mutant mouse model with increased superoxide--lack of nitric oxide?. J Urol. 2010;183(2):780-785.

Valli A, Rosner M, Fuchs C, Siegel N, Bishop CE, Dolznig H, Madel U, Feichtinger W, Atala A, Hengstschlager M. Embryoid body formation of human amniotic fluid stem cells depends on mTOR. Oncogene. 2010;29(7):966-977.

Pan C, Lu B, Chen H, Bishop CE. Reprogramming human fibroblasts using HIV-1 TAT recombinant proteins OCT4, SOX2, KLF4 and c-MYC. Mol Biol Rep. 2010;37(4):2117-2124.

Pan CY, Hicks A, Guan X, Chen H, Bishop CE. SNL fibroblast feeder layers support derivation and maintenance of human induced pluripotent stem cells. J Genet Genomics. 2010;37(4):241-248.

Pan C, Lan X, Chen H, Bishop CE. An economical single-sided antibody incubation method for Western blotting. J Virol Methods. 2010;169(2):409-411.

Bishop CE. Tissue engineering in andrology [abstract]. J Androl. 2009;30(Suppl):12.

Anderson PD, Lam M-Y, Poirier C, Bishop CE, Nadeau JH. The role of the mouse Y chromosome on susceptibility to testicular germ cell tumors. Cancer Res. 2009;69(8):3614-3618.

Chung Y, Bishop CE, Treff NR, Walker SJ, Sandler VM, Becker S, Klimanskaya I, Wun W-S, Atala A, Lanza R, et al. Reprogramming of human somatic cells using human and animal oocytes. Cloning Stem Cells. 2009;11(2):213-223.

Fullhase C [Fuellhase C], Soler R, Lu B, Bishop CE, Andersson KE. Increased levels of superoxide ions affects bladder function in a new mutant mouse model [abstract]. Eur Urol Suppl. 2009;8(4):176.

Soler R, Fuellhase C, Lu B, Bishop C, Andersson K. Bladder dysfunction in a new animal model of increased levels of superoxide ions [abstract]. Neurourol Urodyn. 2009;28(7):809-810.

Lu B, Poirier C, Gaspar T, Gratzke C, Harrison W, Busija D, Matzuk MM, Andersson K-E, Overbeek PA, Bishop CE. A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice. Biol Reprod. 2008;78(4):601-610.

De Filippo RE, Bishop CE, Filho LF, Yoo JJ, Atala A. Tissue engineering a complete vaginal replacement from a small biopsy of autologous tissue. Transplantation. 2008;86(2):208-214.

Poirier C, Moran JL, Kovanci E, Petit DC, Beier DR, Bishop CE. Three loci on mouse chromosome 5 and 10 modulate sex determination in XX Ods/+ mice [letter]. Genesis. 2007;45(7):452-455.

Lu B, Geurts AM, Poirier C, Petit DC, Harrison W, Overbeck PA, Bishop CE. Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system. Mamm Genome. 2007;18(5):338-346.

Feng S, Bogatcheva NV, Truong A, Korchin B, Bishop CE, Klonisch T, Agoulnik IU, Agoulnik AI. Developmental expression and gene regulation of insulin-like 3 receptor RXFP2 in mouse male reproductive organs. Biol Reprod. 2007;77(4):671-680.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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