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Upper limb spasticity, the tightening and stiffening of wrist, elbow and finger muscles, can occur weeks, months or years after a stroke. Learn more about the symptoms of upper limb spasticity and new treatment options to help patients live better and more active lives.

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Allison Brashear, M.D.

Allison Brashear, M.D.

Chair, Neurology
Professor, Neurology
Contact Information
Appointment:
336-716-4101
Office:
336-716-4101
Fax:
336-716-2810
Clinical Specialties
Movement Disorders, Neuromuscular Diseases, Botulinum Toxin
Education & Training
  BADepauw University1983
  MDIndiana University School of Medicine1987
ResidencyNeurologyIndiana Univ Med Ctr & Hosps1991
InternshipMedicineIndiana Univ Med Ctr & Hosps1988
Board Certifications
American Board of Psychiatry & Neurology , Neurology
Memberships
American Academy of Neurology
NPI Number
1881673713
Allison Brashear, M.D.

Allison Brashear, M.D.

Chair, Neurology
Professor, Neurology
Contact Information
Appointment:
336-716-4101
Office:
336-716-4101
Fax:
336-716-2810
Recent Publications
Brashear A, Elovic E, eds. . In: Spasticity: diagnosis and management. New York: Demos Medical Publishing; 2011: .


Brashear A, Elovic E. Why is spasticity important?. In: Brashear A, Elovic E, eds. Spasticity: diagnosis and management. New York: Demos Medical Publishing; 2011: 3-4.


Brashear A. Botulinum toxin in the treatment of upper limb spasticity. In: Brashear A, Elovic E, eds. Spasticity: diagnosis and management. New York: Demos Medical Publishing; 2011: 131-140.




Brashear A, Hill DF, Boggs N, Ozelius L, Sweadner KJ, Light L, Stacy M, Snively BM, McCall WV. Psychosis: part of the rapid-onset dystonia-Parkinsonism (RDP) phenotype? [abstract]. Neurology. 2011; 76(9 Suppl 4):A640.


Evidente VGH, Fernandez HH, LeDoux MS, Brashear A, Marx MW, Grafe SK, Comella CL. Flexible dosing with incobotulinumtoxin-A (Xeomin); botulinum neurotoxin type-A, free from accessory proteins) in cervical dystonia [abstract]. Eur J Neurol. 2011; 18(Suppl 2):511.


Truong D, Brodsky M, Lew M, Brashear A, Jankovic J, Molho E, Orlova O, Timerbaeva S. Long-term efficacy and safety of botulinum toxin type A (Dysport) in cervical dystonia. Parkinsonism Relat Disord. 2010; 16(5):316-323.


Brashear A, Hill D, Snively BM, Sweadner KJ, Ozelius L. De novo and recurrent mutations in ATP1A3 are common in rapid-onset dystonia-Parkinsonism [abstract]. Neurology. 2010; 74(9 Suppl 2):A204.


Yablon SA, Simpson D, Gracies JM, Barbano R, Brashear A. Tizanidine improves geriatric depression scale scores in stroke and brain injury survivors with spastic hemiparesis: post-hoc analysis from a randomized, double-blind, placebo-controlled trial [abstract]. Neurology. 2010; 74(9 Suppl 2):A409-A410.


Brashear A, Hill DF, Snively B, Sweadner KJ, Ozelius L. Now triggers in rapid-onset dystonia-Parkinsonism (RDP) [abstract]. Neurology. 2010; 74(9 Suppl 2):A205.


Brashear A. Botulinum toxin type A: exploring new indications. Drugs Today (Barc). 2010; 46(9):671-682.


Simpson DM, Gracies JM, Yablon SA, Barbano R, Brashear A. Botulinum neurotoxin versus tizanidine in upper limb spasticity: a placebo-controlled study. J Neurol Neurosurg Psychiatry. 2009; 80(4):380-385.


Brashear A, Lambeth K. Spasticity. Curr Treat Options Neurol. 2009; 11(3):153-161.




Sacino A, Hampton TG, Lingrel JB, Brashear A, Sweadner KJ. Rapid onset dystonia-parkinsonism: symptoms in a mouse deficient in Na,K-ATPase alpha3 [abstract]. Mov Disord. 2009; 24(Suppl 1):S112-S113.


Gracies J-M, Yablon S, Raghavan P, Barbano R, Brashear A, Simpson D. Relationship between active function and tone in a placebo-controlled study of botulinum neurotoxin vs tizanidine in upper limb spasticity [abstract]. Arch Phys Med Rehabil. 2009; 90(10):e5-e6.


Barbano RL, Ozelius L, Hill DF, Brashear A. Variable phenotypic expression of rapid onset dystonia parkinsonism in a newly discovered Italian family with a T613M mutation in the ATP1A3 gene [abstract]. In: Abstracts of the 61st Annual Meeting of the American Academy of Neurology; 2009 April 25 - May 2; Seattle (WA). 2009; ():IN2-1.003.


Simpson DM, Blitzer A, Brashear A, Comella C, Dubinsky R, Hallett M, Jankovic J, Karp B, Ludlow CL, Miyasaki JM, et al. Assessment: botulinum neurotoxin for the treatment of movement disorders (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 2008; 70(19):1699-1706.




Brashear A. Clinical comparisons of botulinum neurotoxin formulations. Neurologist. 2008; 14(5):289-298.


Brashear A, Dobyns WB, de Carvalho Aguiar P, Borg M, Frijns CJM, Gollamudi S, Green A, Guimaraes J, Haake B, Klein C, et al. The phenotypic spectrum of rapid-onset dystonia-parkinsonism (RDP) and mutations in the ATP1A3 gene. Brain. 2007; 130(Pt 3):828-835.


Yablon SA, Brashear A, Gordon MF, Elovic DP, Turkel CC, Daggett S, Liu J, Brin MF. Formation of neutralizing antibodies in patients receiving botulinum toxin type A for treatment of poststroke spasticity: a pooled-data analysis of three clinical trials. Clin Ther. 2007; 29(4):683-690.


Brashear A, Farmer D, Wood F, Bressman SB, Dobyns WB, Ozelius LO. ATP1A3 mutations in rapid-onset dystonia Parkinsonism: is there more to the story? [abstract]. Ann Neurol. 2006; 60(Suppl 10):S11.


Jankovic J, Hunter C, Dolimbek BZ, Dolimbek GS, Adler CH, Brashear A, Comella CL, Gordon M, Riley DE, Sethi K, et al. Clinico-immunologic aspects of botulinum toxin type B treatment of cervical dystonia. Neurology. 2006; 67(12):2233-2235.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Allison Brashear, M.D.

Allison Brashear, M.D.

Chair, Neurology
Professor, Neurology
Contact Information
Appointment:
336-716-4101
Office:
336-716-4101
Fax:
336-716-2810
YWCA Photo

Dr. Allison Brashear, chair, Neurology, was recognized for her leadership by the Winston-Salem YWCA, as one of 16 recipients of its 2010 Women of Vision Awards.

As the only woman to lead a clinical department at Wake Forest Baptist, Dr. Brashear is a role model for female students, residents and faculty. Within the Medical Center, Dr. Brashear serves on three senior leadership boards and plays a pivotal role in the changes and strategies that are being implemented to improve health care in our community.

Dr. Brashear also fulfills her passion for helping women and girls in our community through her efforts on the Women’s Fund Board of Directors. She also chairs the Fund’s grant committee. 

Last Updated 1/31/2012
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