Profile

Tina Ellis Brinkley, Ph.D.Wake Forest School of Medicine

Tina Ellis Brinkley, Ph.D.

Assistant Professor,

Contact Information

Academic: 336-713-8558 | Department: 336-713-8570

Email: tbrinkle@wakehealth.edu

Additional Languages

Spanish

Education & Training

  • B.A., University of North Carolina-Chapel Hill, 2001
  • M.A., University of Maryland-College Park, 2003
  • Ph.D., University of Maryland-College Park, 2006
  • Fellowship, Internal Medicine, WFU School of Medicine, 2008

Memberships

  • Obesity Society
  • Am Coll Of Sports Medicine
  • Am Heart Association
Tina Ellis Brinkley, Ph.D.

Tina Ellis Brinkley, Ph.D.

Assistant Professor, Gerontology and Geriatric Medicine

Research Interests

Exercise; Adipose Tissue; Pericardium; Scavenger Receptors, Class E; Aging
More »

Contact Information

Academic: 336-713-8558 | Department: 336-713-8570

Email: tbrinkle@wakehealth.edu

Recent Publications

Effects of resistance training with and without caloric restriction on arterial stiffness in overweight and obese older adults. Jefferson ME, Nicklas BJ, Chmelo EA, Crotts CI, Shaltout HA, Diz DI, Marsh AP, Brinkley TE.. Am J Hypertens. 2016;29(4):494-500.

Adiposity is associated with gender-specific reductions in left ventricular myocardial perfusion during dobutamine stress. Hall ME, Brinkley TE, Chughtai H, Morgan TM, Hamilton CA, Jordan JH, Stacey RB, Soots S, Hundley WG.. PLoS One. 2016;11(1):e0146519.

Insulin resistance correlations with executive functioning in sedentary older adults: the INFINITE study [abstract]. Dougherty A, Brinkley TE, Lyles MF, Nicklas BJ, Williams JA, Hugenschmidt CE.. J Am Geriatr Soc. 2016;64(Suppl 1):S262-S263.

Caloric restriction during aerobic training enhances cardiorespiratory fitness in obese, older adults: a randomized controlled trial: 1529 Board #182 June 2, 9: 00 AM - 10: 30 AM [abstract]. Nicklas BJ, Crotts C, Chmelo EA, Yow D, Gordon M, Lyles MF, Beavers KM, Houston DK, Hugenschmidt C, Leng I, Brinkley TE.. Med Sci Sports Exerc. 2016;48(5 Suppl 1):416-417.

Gait speed response to aerobic versus resistance exercise training in older adults. Henderson RM, Leng XI, Chmelo EA, Brinkley TE, Lyles MF, Marsh AP, Nicklas BJ.. Aging Clin Exp Res. 2016;():.

Increased cardiovascular stiffness and impaired age-related functional status. Andersen MM, Kritchevsky SB, Morgan TM, Hire DG, Vasu S, Brinkley TE, Kitzman DW, Hamilton CA, Soots S, Hundley WG.. J Gerontol A Biol Sci Med Sci. 2015;70(5):545-553.

Heterogeneity of physical function responses to exercise training in older adults. Chmelo EA, Crotts CI, Newman JC, Brinkley TE, Lyles MF, Leng X, Marsh AP, Nicklas BJ.. J Am Geriatr Soc. 2015;63(3):462-469.

Vitamin K status in black and white older adults and its relationship with cardiovascular disease risk [abstract]. Shea K, Booth S, Brinkley T, Kritchevsky S.. FASEB J. 2015;29(Suppl 1):906.4.

Soluble receptor for advanced glycation end products and the risk for incident heart failure: the Atherosclerosis Risk in Communities Study. Lazo M, Halushka MK, Shen L, Maruthur N, Rebholz CM, Rawlings AM, Hoogeveen RC, Brinkley TE, Ballantyne CM, Astor BC, Selvin E.. Am Heart J. 2015;170(5):961-967.

MiRNAs as biomarkers of the gait speed response to aerobic exercise training in obese older adults [abstract]. Zhang T, Liu KQ, Brinkley TE, Feng X, Marsh A, Nicklas B, Zhou XB, Kritchevsky SB.. Gerontologist. 2015;55(Suppl 2):338.

Comparison of aerobic versus resistance training for improving gait speed in older adults [abstract]. Henderson R, Leng I, Chmelo E, Brinkley TE, Lyles MF, Marsh AP, Nicklas BJ.. J Am Geriatr Soc. 2014;62(Suppl 1):S154.

Periaortic fat and cardiovascular risk: a comparison of high-risk older adults and age-matched healthy controls. Brinkley TE, Leng X, Chughtai HL, Nicklas BJ, Kritchevsky SB, Ding J, Kitzman DW, Hundley WG.. Int J Obes (Lond). 2014;38(11):1397-1402.

Aerobic exercise training and self-reported fatigue in older, obese adults [abstract]. Gordon MM, Chmelo E, Crotts C, Lyles M, Brinkley T, Newman J, Rejeski WJ, Nicklas B.. Med Sci Sports Exerc. 2014;46(5):224.

Combined reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease in sedentary elders with functional limitations. Vaz Fragoso CA, Hsu FC, Brinkley T, Church T, Liu CK, Manini T, Newman AB, Stafford RS, McDermott MM, Gill TM.. J Am Med Dir Assoc. 2014;15(9):665-670.

The angiotensin-converting enzyme I/D polymorphism and exercise-induced changes in physical function among Caucasian older adults [abstract]. Buford TW, Hsu FC, Brinkley TE, Carter CS, Church TS, Dodson JA, Goodpaster BH, McDermott MM, Nicklas BJ, Yank V, Johnson JA, Pahor M.. Med Sci Sports Exerc. 2014;46(5 Suppl 1):598.

Aortic stiffness predicts blood pressure responses to exercise in obese older adults [abstract]. Brinkley TE, Gordon MM, Chmelo EA, Jefferson M, Lyles MF, Hundley WG, Gregory HW, Nicklas BJ.. Med Sci Sports Exerc. 2013;45(5 Suppl 1):11.

Does 400 meter walk time predict Vo(2) peak in obese, older adults? [abstract]. Chmelo E, Gordon M, Crotts C, Lyles MF, Brinkley T, Blocker J, Nicklas BJ.. Med Sci Sports Exerc. 2013;45(5 Suppl 1):573.

Heart rate recovery is associated with central adiposity in obese older adults [abstract]. Jefferson ME, Gordon MM, Chmelo EA, Lyles MF, Nicklas BJ, Brinkley TE.. Med Sci Sports Exerc. 2013;45(5 Suppl 1):11.

Ectopic fat is associated with gender-specific reductions in left ventricular myocardial perfusion index during dobutamine stress [abstract]. Hall ME, Brinkley TE, Morgan T, Hamilton CA, Jordan JH, Stacey RB, Chugtai H, Soots S, Little WC, Hundley WG.. Circulation. 2013;128(22 Suppl):A17990.

Total and abdominal adiposity are associated with inflammation in older adults using a factor analysis approach. Brinkley TE, Hsu FC, Beavers KM, Church TS, Goodpaster BH, Stafford RS, Pahor M, Kritchevsky SB, Nicklas BJ.. J Gerontol A Biol Sci Med Sci. 2012;67(10):1099-1106.

Epicardial, pericardial and periaortic fat are elevated in older adults at high cardiac risk [abstract]. Brinkley TE, Kitzman DW, Ding J, Nicklas BJ, Kritchevsky SB, Hundley WG.. Arterioscler Thromb Vasc Biol. 2012;32(5 Suppl):A132.

Pericardial fat is associated with carotid stiffness in the Multi-Ethnic Study of Atherosclerosis. Brinkley TE, Hsu F-C, Carr JJ, Hundley WG, Bluemke DA, Polak JF, Ding J.. Nutr Metab Cardiovasc Dis. 2011;21(5):332-338.

Pericardial fat loss in postmenopausal women under conditions of equal energy deficit. Brinkley TE, Ding J, Carr JJ, Nicklas BJ.. Med Sci Sports Exerc. 2011;43(5):808-814.

Intraperitoneal fat is associated with thickening of the thoracic aorta in individuals at high risk for cardiovascular events [abstract]. Chughtai H, Morgan TM, Hamilton CA, Charoenpanichkit C, Ding J, Brinkley TE, Hundley WG.. J Am Coll Cardiol. 2011;57(14 Suppl 1):E1597.

Caloric restriction, aerobic exercise training and soluble lectin-like oxidized LDL receptor-1 levels in overweight and obese post-menopausal women. Brinkley TE, Wang X, Kume N, Mitsuoka H, Nicklas BJ.. Int J Obes (Lond). 2011;35(6):793-799.

Intraperitoneal fat is associated with thickening of the thoracic aorta in individuals at high risk for cardiovascular events. Chughtai HL, Morgan TM, Hamilton CA, Charoenpanichkit C, Ding J, Brinkley TE, Hundley WG.. Obesity (Silver Spring). 2011;19(9):1784-1790.

Pericardial fat and myocardial perfusion in asymptomatic adults from the Multi-Ethnic Study of Atherosclerosis. Brinkley TE, Jerosch-Herold M, Folsom AR, Carr JJ, Hundley WG, Allison MA, Bluemke DA, Burke GL, Szklo M, Ding J.. PLoS ONE. 2011;6(12):e28410.

Hepatic lipase gene -514C greater than T variant is associated with exercise training-induced changes in VLDL and HDL by lipoprotein lipase. Brinkley TE, Halverstadt A, Phares DA, Ferrell RE, Prigeon RL, Hagberg JM, Goldberg AP.. J Appl Physiol. 2011;111(6):1871-1876.

Adiposity and isolated systolic hypertension in older adults: differential associations by sex and treatment status [abstract]. Brinkley TE, Sutton-Tyrrell K, Kanaya A, Harrris TB [sic] [Harris TB], Kim LJ, Lakatta EG, Simonsick EM, Kritchevsky SB.. Gerontologist. 2011;51(Suppl 2):584.

Effect of Ginkgo biloba on blood pressure and incidence of hypertension in elderly men and women. Brinkley TE, Lovato JF, Arnold AM, Furberg CD, Kuller LH, Burke GL, Nahin RL, Lopez OL, Yasar S, Williamson JD.. Am J Hypertens. 2010;23(5):528-533.

Visceral fat is associated with an adverse increase in the thickness of the wall of the ascending thoracic aorta [abstract]. Chughtai H, Morgan TM, Hamilton CA, Charoenpanichkit C, Ding J, Brinkley TE, Hundley WG.. J Cardiovasc Magn Reson. 2010;12(Suppl 1):P126.

Effect of exercise training on chronic inflammation. Beavers KM, Brinkley TE, Nicklas BJ.. Clin Chim Acta. 2010;411(11-12):785-793.

Renal sinus fat and poor blood pressure control in middle-aged and elderly individuals at risk for cardiovascular events. Chughtai HL, Morgan TM, Rocco M, Stacey B, Brinkley TE, Ding J, Nicklas B, Hamilton C, Hundley WG.. Hypertension. 2010;56(5):901-906.

Greater pericardial fat is associated with higher resting myocardial blood flow in the Multi-Ethnic Study of Atherosclerosis [abstract]. Brinkley TE, Jerosch-Herold M, Folsom AR, Carr JJ, Hundley WG, Allison MA, Bluemke DA, Burke GL, Szklo M, Ding J.. Diabetes. 2010;59(Suppl 1):A125.

Chronic inflammation is associated with low physical function in older adults across multiple comorbidities. Brinkley TE, Leng X, Miller ME, Kitzman DW, Pahor M, Berry MJ, Marsh AP, Kritchevsky SB, Nicklas BJ.. J Gerontol A Biol Sci Med Sci. 2009;64(4):455-461.

Plasma oxidized low-density lipoprotein levels and arterial stiffness in older adults: the Health, Aging, and Body Composition Study. Brinkley TE, Nicklas BJ, Kanaya AM, Satterfield S, Lakatta EG, Simonsick EM, Sutton-Tyrrell K, Kritchevsky SB.. Hypertension. 2009;53(5):846-852.

The ACE I/D genotype and improvement in 400-meter walk performance with exercise training in the Lifestyle Intervention and Independence for Elders Pilot (LIFE-P) [abstract]. Brinkley TE, Hsu F, Hawkins GA, Kritchevsky SB, Pahor M, Nicklas BJ.. J Am Geriatr Soc. 2009;57(Suppl 1):S123.

Weight loss reduces plasma soluble lectin-like oxidized LDL receptor-1 levels in overweight and obese postmenopausal women [abstract]. Brinkley TE, Wang X, Kume N, Mitsuoka H, Nicklas BJ.. Circulation. 2009;119(10):e290-e291.

Exercise training, NADPH oxidase p22phox gene polymorphisms, and hypertension. Feairheller DL, Brown MD, Park Y-Y, Brinkley TE, Basu S, Hagberg JM, Ferrell RE, Fenty-Stewart NM.. Med Sci Sports Exerc. 2009;41(7):1421-1428.

The relationship of oxidative stress and cholesterol with dipping status before and after aerobic exercise training. Sturgeon KM, Fenty-Stewart NM, Diaz KM, Brinkley TE, Dowling TC, Brown MD.. Blood Press. 2009;18(4):171-179.

Exercise training as a treatment for chronic inflammation in the elderly. Nicklas BJ, Brinkley TE.. Exerc Sport Sci Rev. 2009;37(4):165-170.

Plasma nitrate/nitrite levels are unchanged after long-term aerobic exercise training in older adults. Brinkley TE, Fenty-Stewart NM, Park J-Y, Brown MD, Hagberg JM.. Nitric Oxide. 2009;21(3-4):234-238.

Renal sinus fat influences the number of medications needed to regulate blood pressure in patients with hypertension [abstract]. Chughtai HL, Morgan TM, Ding JZ, Brinkley TE, Rocco M, Hamilton CA, Hundley WG.. Circulation. 2009;120(18 Suppl 2):S1017.

Caloric restriction with and without aerobic exercise decreases pericardial fat in overweight and obese postmenopausal women [abstract]. Brinkley TE, Ding J, Carr JJ, Nicklas BJ.. Obesity (Silver Spring). 2009;17(Suppl 2):S263.

Variation in the human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gene is associated with plasma soluble LOX-1 levels. Brinkley TE, Kume N, Mitsuoka H, Brown MD, Phares DA, Ferrell RE, Kita T, Hagberg JM.. Exp Physiol. 2008;93(9):1085-1090.

Exercise training and plasma C-reactive protein and interleukin-6 in elderly people. Nicklas BJ, Hsu F-C, Brinkley TJ, Church T, Goodpaster BH, Kritchevsky SB, Pahor M.. J Am Geriatr Soc. 2008;56(11):2045-2052.

Increased pericardial fat is associated with carotid artery stiffness: the Multi-Ethnic Study of Atherosclerosis (MESA) [abstract]. Brinkley TE, Carr JJ, Hundley WG, Hsu FC, Bluemke DA, Polak JF, Ding JZ.. Circulation. 2008;118(18 Suppl 2):S1153.

Chronic inflammation is associated with low physical function in older adults across multiple comorbidities [abstract]. Nicklas BJ, Brinkley T, Leng X, Miller M, Kitzrnan D [sic] [Kitzman D], Berry M, Marsh A, Pahor M, Kritchevsky S.. Gerontologist. 2008;48(Special Issue 3):491-492.

High plasma oxidized low-density lipoprotein levels are associated with increased arterial stiffness: is physical activity a mediator? [abstract]. Ellis TJ [Brinkley TE], Nicklas BJ, Kanaya AM, Satterfield S, Simonsick EM, Sutton-Tyrrell K, Kritchevsky SB.. Circulation. 2008;117(11):e280.

Elevated soluble lectin-like oxidized LDL receptor-1 (sLOX-1) levels in obese postmenopausal women. Brinkley TE, Kume N, Mitsuoka H, Phares DA, Hagberg JM.. Obesity (Silver Spring). 2008;16(6):1454-1456.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Gerontology and Geriatric Medicine

Tina Ellis Brinkley, Ph.D.

Tina Ellis Brinkley, Ph.D.

Assistant Professor, Gerontology and Geriatric Medicine

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