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Evgeny Budygin, Ph.D.Wake Forest School of Medicine

Evgeny Budygin, Ph.D.

Associate Professor,

Contact Information

Academic: 336-716-4072 | Department: 336-716-4368

Email: ebudygin@wakehealth.edu

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Education & Training

  • Ph.D., Academy Medical Science of USSR-Russia, 1993
  • Pharm.D., I.P. Pavlov Leningrad-Russia, 1998
  • Fellowship, Academy Medical Science of USS, 1993
  • Fellowship, Academy Medical Science of USS, 1997
  • Fellowship, Univ of NC at Chapel Hill, 2000
  • Fellowship, WFU School of Medicine, 2002

Memberships

  • Research Society On Alcoholism
  • Int Soc for Biomed Res on Alco
  • Society for Neuroscience
Evgeny Budygin, Ph.D.

Evgeny Budygin, Ph.D.

Associate Professor, Neurobiology & Anatomy

Research Interests

Dopamine; Corpus Striatum; Nucleus Accumbens; Ethanol; Cocaine
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Contact Information

Academic: 336-716-4072 | Department: 336-716-4368

Email: ebudygin@wakehealth.edu

Related Links

Recent Publications

Dopamine transporter mutant animals: a translational perspective. Efimova EV, Gainetdinov RR, Budygin EA, Sotnikova TD.. J Neurogenet. 2016;30(1):5-15.

Cross-hemispheric dopamine projections have functional significance. Fox ME, Mikhailova MA, Bass CE, Takmakov P, Gainetdinov RR, Budygin EA, Wightman RM.. Proc Natl Acad Sci U S A. 2016;113(25):6985-6990.

Norepinephrine and dopamine transmission in 2 limbic regions differentially respond to acute noxious stimulation. Park J, Bucher ES, Budygin EA, Wightman RM.. Pain. 2015;156(2):318-327.

Targeted genetic manipulations of neuronal subtypes using promoter-specific combinatorial AAVs in wild-type animals. Gompf HS, Budygin EA, Fuller PM, Bass CE.. Front Behav Neurosci. 2015;9():152.

Real time adenosine fluctuations detected with fast-scan cyclic voltammetry in the rat striatum and motor cortex. Adamah-Biassi EB, Almonte AG, Blagovechtchenski E, Grinevich VP, Weiner JL, Bonin KD, Budygin EA.. J Neurosci Methods. 2015;256():56-62.

Effects of ethanol on real-time adenosine dynamics in the rat striatum [abstract]. Adamah-Biassi EB, Almonte AG, Bonin KD, Weiner JL, Budygin EA.. Alcohol Clin Exp Res. 2015;39(Suppl 1):182A.

Exploring the neurochemical basis of alcohol addiction-related behaviors: translational research. Budygin EA, Weiner JL.. Transl Biomed. 2015;6(Suppl Spec):.

Modulation of ethanol and sucrose drinking behaviors by optogenetic stimulation of the mesolimbic dopamine system [abstract]. Budygin EA, Grinevich VP, Carr A, Chappell AM, Bass CE, Bonin KD, Weiner JL.. Alcohol Clin Exp Res. 2014;38(Suppl 1):169A.

Understanding the role alpha 7 nicotinic receptors play in dopamine efflux in nucleus accumbens. Maex R, Grinevich VP, Grinevich V, Budygin E, Bencherif M, Gutkin B.. ACS Chem Neurosci. 2014;5(10):1032-1040.

Terminal effects of optogenetic stimulation on dopamine dynamics in rat striatum. Bass CE, Grinevich VP, Kulikova AD, Bonin KD, Budygin EA.. J Neurosci Methods. 2013;214(2):149-155.

Preliminary evidence that optogenetic activation of VTA dopamine cells inhibits alcohol self-administration in male Long Evans rats [abstract]. Grinevich VP, Bass CE, Gioia D, Chappell AM, Bonin KD, Weiner JL, Budygin EA.. Alcohol Clin Exp Res. 2013;37(Suppl 2):229A.

Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Bass CE, Grinevich VP, Gioia D, Day-Brown JD, Bonin KD, Stuber GD, Weiner JL, Budygin EA.. Front Behav Neurosci. 2013;7():173.

Background cholinergic tone determines the effect of agonists of alpha7-type nicotinic acetylcholine receptors on the efflux of dopamine in a circuit model [abstract]. Maex R, Grinevich V, Budygin E, Bencherif M, Gutkin B.. Soc Neurosci Abstr. 2013;2013(Neuroscience Meeting Planner):.

Aversive stimulus differentially triggers subsecond dopamine release in reward regions. Budygin EA, Park J, Bass CE, Grinevich VP, Bonin KD, Wightman RM.. Neuroscience. 2012;201():331-337.

Activation of VTA GABA neurons disrupts reward consumption. van Zessen R, Phillips JL, Budygin EA, Stuber GD.. Neuron. 2012;73(6):1184-1194.

Manipulating brain dopamine transmission through optogenetics [abstract]. Budygin EA.. In: Proceedings of the 17th Multidisciplinary International Conference on Neuroscience and Biological Psychiatry: 'Stress and Behavior' ISBS Conference; 2012 May 16-19; St. Petersburg (Russia). 2012;():7-8.

Differential regulation of accumbal dopamine transmission in rats following cocaine, heroin and speedball self-administration. Pattison LP, McIntosh S, Budygin EA, Hemby SE.. J Neurochem. 2012;122(1):138-146.

Optogenetic stimulation of striatal dopamine release detected in brain slices [abstract]. Budygin EA, Grinevich VP, Bonin KD, Bass CE.. Soc Neurosci Abstr. 2012;2012(Neuroscience Meeting Planner):.

A computational model dissecting out the contribution of various receptor subtypes to nicotine-evoked dopamine efflux [abstract]. Maex R, Grinevich V, Budygin E, Bencherif M, Gutkin B.. Soc Neurosci Abstr. 2012;2012(Neuroscience Meeting Planner):.

Multiple nicotinic receptor subtypes modulate nicotine-evoked dopamine efflux in rat striatum [abstract]. Grinevich V, Budygin E, Maex R, Gutkin B, Hauser TA, Bencherif M.. Soc Neurosci Abstr. 2012;2012(Neuroscience Meeting Planner):.

Speedball induced changes in electrically stimulated dopamine overflow in rat nucleus accumbens. Pattison LP, Bonin KD, Hemby SE, Budygin EA.. Neuropharmacology. 2011;60(2-3):312-317.

Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior. Adamantidis AR, Tsai H-C, Boutrel B, Zhang F, Stuber GD, Budygin EA, Tourino C, Bonci A, Deisseroth K, de Lecea L.. J Neurosci. 2011;31(30):10829-35.

[Role of the brain dopaminergic and serotoninergic systems in psychopharmacological effects of ladasten and sydnocarb] [Russian]. Zimin IA, Abaimov DA, Budygin EA, Zolotarev IuA, Kovalev GI.. Eksp Klin Farmakol. 2010;73(2):2-5.

Optogenetic control of striatal dopamine release in rats. Bass CE, Grinevich VP, Vance ZB, Sullivan RP, Bonin KD, Budygin EA.. J Neurochem. 2010;114(5):1344-1352.

Dopamine uptake changes associated with cocaine self-administration. Oleson EB, Talluri S, Childers SR, Smith JE, Roberts DCS, Bonin KD, Budygin EA.. Neuropsychopharmacology. 2009;34(5):1174-1184.

Increased phasic dopamine signaling in the mesolimbic pathway during social defeat in rats. Anstrom KK, Miczek KA, Budygin EA.. Neuroscience. 2009;161(1):3-12.

Effects of nicotine on real-time dopamine dynamics in rat nucleus accumbens: in vivo voltammetric study [abstract]. Grinevich VP, O'Connor JA, Bencherif M, Budygin EA.. Biochem Pharmacol. 2009;78(7 Special Issue):916.

Effect of partial nicotinic agonists on real-time dopamine responses in rat nucleus accumbens: in vivo voltammetric study [abstract]. O'Connor JA, Budygin EA, Grinevich VP, Bencherif M.. Biochem Pharmacol. 2009;78(7):917.

Ethanol-induced hyperactivity is associated with hypodopaminergia in the 22-TNJ ENU-mutated mouse. Mathews TA, Brookshire BR, Budygin EA, Hamre K, Goldowitz D, Jones SR.. Alcohol. 2009;43(6):421-431.

Real-time voltammetric detection of cocaine-induced dopamine changes in the striatum of freely moving mice. Oleson EB, Salek J, Bonin KD, Jones SR, Budygin EA.. Neurosci Lett. 2009;467(2):144-146.

A neurochemical comparison of striatal dopamine function in drinking monkeys [abstract]. Mathews TA, Brookshire BR, Budygin EA, Daunais JB, Friedman DP, Jones SR.. Alcohol Clin Exp Res. 2008;32(6 Suppl 1):35A.

Terminal effects of chronic alcohol exposure on dopamine dynamics in rat striatum [abstract]. Budygin EA, Oleson EB, Mathews TA, Lack AK, Diaz M, McCool BA, Jones SR.. Alcohol Clin Exp Res. 2007;31(6 Suppl):83A.

Effects of chronic alcohol exposure on dopamine uptake in rat nucleus accumbens and caudate putamen. Budygin EA, Oleson EB, Mathews TA, Lack AK, Diaz MR, McCool BA, Jones SR.. Psychopharmacology (Berl). 2007;193(4):495-501.

Extracting the basal extracellular dopamine concentrations from the evoked responses: re-analysis of the dopamine kinetics. Chen KC, Budygin EA.. J Neurosci Methods. 2007;164(1):27-42.

Dopamine uptake inhibition is positively correlated with cocaine-induced stereotyped behavior. Budygin EA.. Neurosci Lett. 2007;429(1):55-58.

No role of the dopamine transporter in acute ethanol effects on striatal dopamine dynamics. Mathews TA, John CE, Lapa GB, Budygin EA, Jones SR.. Synapse. 2006;60(4):288-294.

Accumbal dopamine release, but not uptake or synthesis, is altered by low and moderate doses of acute ethanol [abstract]. Budygin EA, Jones SR.. Alcohol Clin Exp Res. 2006;30(6 Suppl):182A.

NMDA receptor deficient mice display altered synaptic function and reward related behaviors [abstract]. John CE, Budygin EA, Weiner JL, Jones SR.. Neuropsychopharmacology. 2006;31(Suppl):S76.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Neurobiology & Anatomy

Evgeny Budygin, Ph.D.

Evgeny Budygin, Ph.D.

Associate Professor, Neurobiology & Anatomy

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