Floyd H. Chilton, Ph.D.
Professor, Physiology & Pharmacology
Comprehensive Cancer Center
Center for Comparative Medicine Research
Center for Public Health Genomics
Translational Science Institute
aging, atherosclerosis/thrombosis, cross(mult/tnslat/inter)discip, genetics/genome, growth & development, immunology/allergy/inflammatio, maternal & child health, metabolism, minority health issues, molecular biology/molecular me, nutrition, prevention
Academic: 336-716-4322 | Department: 336-713-7105
Media Medical Expert »
Howard TD, Mathias RA, Seeds MC, Herrington DM, Hixson JE, Shimmin LC, Hawkins GA, Sellers M, Ainsworth HC, Sergeant S, Miller LR, Chilton FH. DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver
. PLoS One. 2014;9(5):e97510.
Kazani S, Arm JP, Boyce J, Chhay H, Dutile S, Wechsler ME, Govindarajulu U, Ivester P, Ainsworth HC, Sergeant S, Chilton FH, Israel E. LTC4 synthase polymorphism modifies efficacy of botanical seed oil combination in asthma
. Springerplus. 2014;3():661.
Chilton F, Mathias R, Seeds M, Herrington D, Hixson J, Hawkins G, Sergeant S, Miller L, Howard T. DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver [abstract]. FASEB J. 2014;28(1 Suppl):373.8.
Chilton F, Lu F, inventors; Wake Forest University Health Sciences, assignee. Compositions, methods, and kits for polyunsaturated fatty acids from microalgae. United States patent US 8,343,753. 2013 Jan 1. 2013;():.
Arm JP, Boyce JA, Wang L, Chhay H, Zahid M, Patil V, Govindarajulu U, Ivester P, Weaver KL, Sergeant S, Israel E, Chilton FH. Impact of botanical oils on polyunsaturated fatty acid metabolism and leukotriene generation in mild asthmatics
. Lipids Health Dis. 2013;12():141.
Sergeant S, Hugenschmidt CE, Rudock ME, Ziegler JT, Ivester P, Ainsworth HC, Vaidya D, Case LD, Langefeld CD, Freedman BI, Bowden DW, Mathias RA, Chilton FH. Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome
. Br J Nutr. 2012;107(4):547-555.
Sergeant S, Lee TC, Ivester P, Ainsworth HC, Case LD, Chilton FH. Botanical oil supplementation alters insulin levels in diabetic/metabolic syndrome subjects in a genotypic-specific manner [abstract]. FASEB J. 2012;26(Meeting Abstracts Suppl):647.11.
Wilson BA, Sergeant S, Ainsworth H, Mathias R, Chilton FH III. Racial differences in plasma omega-3 long chain fatty acid levels in a cohort of African Americans and European Americans with diabetes and metabolic syndrome [abstract]. FASEB J. 2012;26(Meeting Abstracts Suppl):266.4.
Mathias RA, Sergeant S, Hugenschmidt CE, Ziegler JT, Ivester P, Case D, Freedman BI, Rudock ME, Langefeld CD, Bowden DW, Chilton FH, et al. The impact of FADS genetic variants on omega-6 polyunsaturated fatty acid metabolism in African Americans
. BMC Genet. 2011;12():article 50.
Mathias RA, Vergara C, Gao L, Rafaels N, Hand T, Campbell M, Bickel C, Ivester P, Sergeant, Chilton FH, et al. FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population
. J Lipid Res. 2010;51(9):2766-2774.
Ivester P, Sergeant S, Danhauer SC, Case LD, Lamb A, Chilton BG, Delar B, Hollingshead ML, Weaver KL, Chilton FH. Effect of a multifaceted, church-based wellness program on metabolic syndrome in 41 overweight or obese congregants. Prev Chronic Dis. 2010;7(4):A81.
Chilton FH, Tucker L. In: The gene smart diet: the revolutionary eating plan that will rewrite your genetic destiny--and melt away the pounds. Emmaus (PA): Rodale;2009: .
Barnes S, Birt DF, Cassileth BR, Cefalu WT, Chilton FH, Farnsworth NR, Raskin I, van Breemen RB, Weaver CM. Technologies and experimental approaches at the National Institutes of Health Botanical Research Centers. Am J Clin Nutr. 2008;87(2 Suppl):476S-480S.
Chilton FH, Rudel LL, Parks JS, Arm JP, Seeds MC. Mechanisms by which botanical lipids affect inflammatory disorders. Am J Clin Nutr. 2008;87(2 Suppl):498S-503S.
Weaver KL, Ivester P, Chilton F. Altering in vivo levels of n-6 and n-3 fatty acids in humans modulates the expression of inflammatory genes [abstract]. FASEB J. 2007;21(5):A61.
Chilton F, inventor; Wake Forest University Health Sciences, assignee. Dietary control of arachidonic acid metabolism. United States patent US 7,138,431. 2006 Nov 21. 2006;():.
For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.
For a list of earlier publications, visit the Carpenter Library Publication Search.