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Profile

Profile
Research

Ralph B. D'Agostino Jr, Ph.D.

Core Director, Comprehensive Cancer Center
Professor, Department of Biostatistics
Translational Science Institute
Comprehensive Cancer Center
Childress Institute
Institute for Regenerative Medicine
Translational Science Institute

Clinical Specialties

Lung Cancer, Cancer Prevention, Epidemiology, Head and Neck Cancers, Pediatric Trauma, Cancer Symptom Management, Prostate Cancer, Diabetes, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus in Adolescents, Breast Cancer

Contact Information

Academic: 336-716-9410 | Department: 336-716-2011

Email: rdagosti@wakehealth.edu

Education & Training

A.B., Bowdoin College , 1988
Ph.D., Harvard University , 1994
A.M., Harvard University , 1989

Ralph B. D'Agostino Jr, Ph.D.

Core Director, Comprehensive Cancer Center
Professor, Department of Biostatistics Translational Science Institute
Comprehensive Cancer Center
Childress Institute
Institute for Regenerative Medicine
Translational Science Institute

Research Interests

cardiac function, diabetes, epidemiology, fitness/physical, genetics/genome, infectious diseases

Contact Information

Academic: 336-716-9410 | Department: 336-716-2011

Email: rdagosti@wakehealth.edu

Recent Publications

Blackham AU, Northrup SA, Willingham M, D'Agostino RB Jr, Lyles DS, Stewart JH IV. Variation in susceptibility of human malignant melanomas to oncolytic vesicular stomatitis virus. Surgery. 2013;153(3):333-343.

Maahs DM, Dabelea D, D'Agostino RB Jr, Andrews JS, Shah AS, Crimmins N, Mayer-Davis EJ, Marcovina S, Imperatore G, Wadwa RP, Daniels SR, Reynolds K, Hamman RF, Dolan LM. Glucose control predicts 2-year change in lipid profile in youth with type 1 diabetes. J Pediatr. 2013;162(1):101-107.

Eckman DM, Stacey RB, Rowe R, D'Agostino R Jr, Kock ND, Sane DC, Torti FM, Yeboah J, Workman S, Lane KS, Hundley WG. Weekly doxorubicin increases coronary arteriolar wall and adventitial thickness. PLoS One. 2013;8(2):e57554.

Jaiswal M, Urbina EM, Wadwa RP, Talton JW, D'Agostino RB Jr, Hamman RF, Fingerlin TE, Daniels S, Marcovina SM, Dolan LM, Dabelea D. Reduced heart rate variability among youth with type 1 diabetes: the SEARCH CVD study. Diabetes Care. 2013;36(1):157-162.

Naik S, D'Agostino R Jr, Knovich MA, Grier D, Harrelson R, McPhail L. Impact of iron overload on immune function for patients undergoing allogeneic transplants for hematologic disorders: results of pilot study [abstract]. Biol Blood Marrow Transplant. 2013;19(2 Suppl 2):S300-S301.

Quandt SA, Grzywacz JG, Talton JW, Trejo G, Tapia J, D'Agostino RB Jr, Mirabelli MC, Arcury TA. Evaluating the effectiveness of a lay health promoter-led, community-based participatory pesticide safety intervention with farmworker families. Health Promot Pract. 2013;14(3):425-432.

Burke AR, Singh RN, Carroll DL, Wood JCS, D'Agostino RB Jr, Ajayan PM, Torti FM, Torti SV. The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy. Biomaterials. 2012;33(10):2961-2970.

Il'yasova D, Spasojevic I, Base K, Zhang H, Wang F, Young SP, Millington DS, D'Agostino RB Jr, Wagenknecht LE. Urinary F2-isoprostanes as a biomarker of reduced risk of type 2 diabetes. Diabetes Care. 2012;35(1):173-174.

Naik S, D'Agostino R Jr, Lamar Z, Graham RM, Vatca M, Agnew E, Higgins A, Levitan D, Hurd D. Outcomes of second transplants for disease recurrence or for myelodysplasia (MDS) developing after an initial transplant (Tx) [abstract]. Biol Blood Marrow Transplant. 2012;18(2 Suppl 2):S340-S341.

Liese AD, Puett RC, Lamichhane AP, Nichols MD, Dabelea D, Lawson AB, Porter DE, Hibbert JD, D'Agostino RB Jr, Mayer-Davis EJ. Neighborhood level risk factors for type 1 diabetes in youth: the SEARCH case-control study. Int J Health Geogr. 2012;11(1):article 1.

Chotenimitkhun R, D'Agostino RB Jr, Lawrence JA, Hamilton CA, Jordan J, Vasu S, Lash TL, Hundley W. Preservation of left ventricular ejection fraction with statins during receipt of anthracycline based chemotherapy [abstract]. J Am Coll Cardiol. 2012;59(13 Suppl):E986.

Soubry A, Il'yasova D, Sedjo R, Wang F, Byers T, Rosen C, Yashin A, Ukraintseva S, Haffner S, D'Agostino R Jr. Increase in circulating levels of IGF-1 and IGF-1/IGFBP-3 molar ratio over a decade is associated with colorectal adenomatous polyps. Int J Cancer. 2012;131(2):512-517.

Bowlby SC, Thomas MJ, D'Agostino RB Jr, Kridel SJ. Nicotinamide phosphoribosyl transferase (Nampt) is required for de novo lipogenesis in tumor cells. PLoS ONE. 2012;7(6):e40195.

Burmeister D, AbouShwareb T, D'Agostino R Jr, Andersson K-E, Christ GJ. Impact of partial urethral obstruction on bladder function: time-dependent changes and functional correlates of altered expression of Ca2+ signaling regulators. Am J Physiol Renal Physiol. 2012;302(12):F1517-28.

Attia A, Rapp SR, Case LD, D'Agostino R, Lesser G, Naughton M, McMullen K, Rosdhal R, Shaw EG. Phase II study of Ginkgo biloba in irradiated brain tumor patients: effect on cognitive function, quality of life, and mood. J Neurooncol. 2012;109(2):357-363.

Mayer-Davis EJ, Davis C, Saadine J, D'Agostino RB Jr, Dabelea D, Dolan L, Garg S, Lawrence JM, Pihoker C, Rodriguez BL, Klein BE, Klein R. Diabetic retinopathy in the SEARCH for Diabetes in Youth Cohort: a pilot study. Diabet Med. 2012;29(9):1148-1152.

Siamakpour-Reihani S, Scarbrough PM, Wang F, Spasojevic I, Base K, Sedjo R, D'Agostino RB Jr, Il'yasova D. Systemic markers of oxidative status and colorectal adenomatous polyps. Ann Epidemiol. 2012;22(8):587-591.

Il'yasova D, Wang F, Spasojevic I, Base K, D'Agostino RB Jr, Wagenknecht LE. Racial differences in urinary F2-isoprostane levels and the cross-sectional association with BMI. Obesity (Silver Spring). 2012;20(10):2147-2150.

Il'yasova D, Wang F, Spasojevic I, Base K, D'Agostino RB Jr, Wagenknecht LE. Urinary F2-isoprostanes, obesity, and weight gain in the IRAS cohort. Obesity (Silver Spring). 2012;20(9):1915-1921.

Kader AK, Sun J, Reck BH, Newcombe PJ, Kim ST, Hsu FC, D'Agostino RB Jr, Tao S, Zhang Z, Turner AR, Platek GT, Spraggs CF, Whittaker JC, Lane BR, Isaacs WB, Meyers DA, Bleecker ER, Torti FM, Trent JM, McConnell JD,. Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial. Eur Urol. 2012;62(6):953-961.

Kwatra SG, Mills KC, Zeitany A, Pearce DJ, Williford PM, D'Agostino RB Jr, Yosipovitch G. Pain and nonmelanoma skin cancer in transplant patients [letter]. J Am Acad Dermatol. 2012;67(6):1387-1388.

Dabelea D, Mayer-Davis EJ, Andrews JS, Dolan LM, Pihoker C, Hamman RF, Greenbaum C, Marcovina S, Fujimoto W, Linder B, Imperatore G, D'Agostino R Jr. Clinical evolution of beta cell function in youth with diabetes: the SEARCH for Diabetes in Youth study. Diabetologia. 2012;55(12):3359-3368.

Jaacks LM, Oza-Frank R, D'Agostino R Jr, Dolan LM, Dabelea D, Lawrence JM, Pihoker C, O'Connor MR, Linder B, Imperatore G, Seid M, Narayan KM, Mayer-Davis EJ. Migration status in relation to clinical characteristics and barriers to care among youth with diabetes in the US. J Immigr Minor Health. 2012;14(6):949-958.

Pettitt DJ, Talton JW, Liese AD, Liu LL, Crimmins N, West NA, D' Agostino RB Jr, Kahn HS. Comparison of two waist circumference measurement protocols: the SEARCH for Diabetes in Youth Study. Pediatr Obes. 2012;7(6):e81-e85.

Mills KC, Kwatra SG, Feneran AN, Pearce DJ, Williford PM, D'Agostino RB, Yosipovitch G. Itch and pain in nonmelanoma skin cancer: pain as an important feature of cutaneous squamous cell carcinoma [letter]. Arch Dermatol. 2012;148(12):1422-1423.

Dabelea D, D'Agostino RB Jr, Mason CC, West N, Hamman RF, Mayer-Davis EJ, Maahs D, Klingensmith G, Knowler WC, Nadeau K. Development, validation and use of an insulin sensitivity score in youths with diabetes: the SEARCH for Diabetes in Youth study. Diabetologia. 2011;54(1):78-86.

Bortsov A, Liese AD, Bell RA, Dabelea D, D'Agostino RB Jr, Hamman RF, Klingensmith GJ, Lawrence JM, Maahs DM, McKeown R, et al. Correlates of dietary intake in youth with diabetes: results from the SEARCH for Diabetes in Youth Study. J Nutr Educ Behav. 2011;43(2):123-129.

Dabelea D, Dolan LM, D'Agostino R Jr, Hernandez AM, McAteer JB, Hamman RF, Mayer-Davis EJ, Marcovina S, Lawrence JM, Pihoker C, et al. Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youth. Diabetologia. 2011;54(3):535-539.

Naik S, Shope D, Albright C, Graham R, Levitan D, Zamkoff K, D'Agostino R Jr, Hurd D. Transplant outcomes in multiple myeloma patients younger versus older than 60 years of age in the era of newer targeted agents [abstract]. Biol Blood Marrow Transplant. 2011;17(2 Suppl 2):S252-S253.

Sedjo RL, D'Agostino RB Jr, Ahnen D, Levin TR, Haffner SM, Tooze JA, Byers T. Lack of association between insulin sensitivity and colorectal adenoma risk. Nutr Cancer. 2011;63(1):6-11.

Holmes JH IV, Carter JE, Neff LP, Cairns BA, d'Agostino RB Jr, Griffin LP, Meredith JW. The effectiveness of regionalized burn care: an analysis of 6,873 burn admissions in North Carolina from 2000 to 2007. J Am Coll Surg. 2011;212(4):487-495.

Liese AD, Bortsov A, Gunther ALB, Dabelea D, Reynolds K, Standiford DA, Liu L, Williams DE, D'Agostino RB Jr, Bell R, et al. Association of DASH diet with cardiovascular risk factors in youth with diabetes mellitus: the SEARCH for Diabetes in Youth Study. Circulation. 2011;123(13):1410-1417.

Jordan JH, D'Agostino RB Jr, Hamilton CA, Hundley WG. Early increase in myocardial cardiovascular magnetic resonance gadolinium signal intensity after anthracyclines but not other agents used to treat breast cancer or hematologic malignancy [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl 1):E782.

Stacey RB, Kock ND, D'Agostino RB Jr, Torti FM, Eckman DM, Sane DC, Workman S, Lane KS, Hundley WG. Doxorubicin associated changes in coronary artery histology [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl 1):E1591.

McCall WV, D'Agostino R Jr, Rosenquist PB, Kimball J, Boggs N, Lasater B, Blocker J. Dissection of the factors driving the placebo effect in hypnotic treatment of depressed insomniacs. Sleep Med. 2011;12(6):557-564.

Shi L, Olson J, D'Agostino R Jr, Linville C, Nicolle MM, Robbins ME, Wheeler KT, Brunso-Bechtold JK. Aging masks detection of radiation-induced brain injury. Brain Res. 2011;1385():307-316.

Wolfson M, Champion H, Rogers T, Neiberg RH, Barker DC, Talton JW, Ip EH, D'Agostino RB Jr, Parries MT, Easterling D. Evaluation of free to grow: head start partnerships to promote substance-free communities. Eval Rev. 2011;35(2):153-188.

Bortsov A, Liese AD, Bell RA, Dabelea D, D'Agostino RB Jr, Hamman RF, Klingensmith GJ, Lawrence JM, Maahs DM, McKeown R, et al. Response to insulin regimen-associated differences in diets of preadolescents with type 1 diabetes [letter]. J Nutr Educ Behav. 2011;43(3):E6.

Burke AR, Singh RN, Carroll DL, Owen JD, Kock ND, D'Agostino R Jr, Torti FM, Torti SV. Determinants of the thrombogenic potential of multiwalled carbon nanotubes. Biomaterials. 2011;32(26):5970-5978.

Mitchel JT, Kim YJ, Choi J, Park G, Cappi S, Horn D, Kist M, D'Agostino RB Jr. Evaluation of data entry errors and data changes to an electronic data capture clinical trial database. Drug Inf J. 2011;45(4):421-430.

Dabelea D, Pihoker C, Talton JW, D'Agostino RB Jr, Fujimoto W, Klingensmith GJ, Lawrence JM, Linder B, Marcovina SM, Mayer-Davis EJ, et al. Etiological approach to characterization of diabetes type: the SEARCH for Diabetes in Youth Study. Diabetes Care. 2011;34(7):1628-1633.

Clausen KA, Blish KR, Birse CE, Triplette MA, Kute TE, Russell GB, D'Agostino RB Jr, Miller LD, Torti FM, Torti SV. SOSTDC1 differentially modulates Smad and beta-catenin activation and is down-regulated in breast cancer. Breast Cancer Res Treat. 2011;129(3):737-746.

Requarth JA, D'Agostino RB Jr, Miller PR. Nonoperative management of adult blunt splenic injury with and without splenic artery embolotherapy: a meta-analysis. J Trauma. 2011;71(4):898-903.

McCall WV, Blocker J, Dagostino R Jr, [sic] [D'Agostino R Jr], Wang J, Shannon W. Both actigraphy data and the intensity of insomnia complaints differ between suicidal and non-suicidal depressed patients enrolled in a hypnotic clinical trial [abstract]. J Sleep Res. 2011;20(Suppl 1):24.

Il'yasova D, Lin P-H, Svetkey L, Kraus W, Spasojevic I, Base K, Wang F, D'Agostino RB, Wagenknecht LE. Cross-sectional and prospective associations between urinary F2-isoprostanes and blood pressure in the IRAS cohort [abstract]. Free Radic Biol Med. 2011;51(Suppl 1):S44.

Il'yasova D, Spasojevic I, Base K, Wang F, D'Agostino RB Jr, Wagenknecht LE. Racial differences in urinary F2-isoprostanes may reflect weak metabolic adaptation in African Americans [abstract]. Free Radic Biol Med. 2011;51(Suppl 1):S62.

Miller LD, Coffman LG, Chou JW, Black MA, Bergh J, D'Agostino R Jr, Torti SV, Torti FM. An iron regulatory gene signature predicts outcome in breast cancer. Cancer Res. 2011;71(21):6728-6737.

Bortsov AV, Liese AD, Bell RA, Dabelea D, D'Agostino RB Jr, Hamman RF, Klingensmith GJ, Lawrence JM, Maahs DM, McKeown R, Marcovina SM, Thomas J, Williams DE, Mayer-Davis EJ. Sugar-sweetened and diet beverage consumption is associated with cardiovascular risk factor profile in youth with type 1 diabetes. Acta Diabetol. 2011;48(4):275-282.

Lorenzo C, Wagenknecht LE, D'Agostino RB Jr, Rewers MJ, Karter AJ, Haffner SM. Insulin resistance, beta-cell dysfunction, and conversion to type 2 diabetes in a multiethnic population: the Insulin Resistance Atherosclerosis Study. Diabetes Care. 2010;33(1):67-72.

Chaosuwannakit N, D'Agostino R Jr, Hamilton CA, Lane KS, Ntim WO, Lawrence J, Melin SA, Ellis LR, Torti FM, Little WC, Hundley WG. Aortic stiffness increases upon receipt of anthracycline chemotherapy. J Clin Oncol. 2010;28(1):166-172.

Corriere MA, Hoyle JR, Craven TE, D'Agostino RB Jr, Edwards MS, Moore PS, Hansen KJ. Changes in left ventricular structure and function following renal artery revascularization. Ann Vasc Surg. 2010;24(1):80-84.

Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Peters SP, Bleecker ER, et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med. 2010;181(4):315-323.

Il'yasova D, Wang F, D'Agostino RB Jr, Hanley A, Wagenknecht LE. Prospective association between fasting NEFA and type 2 diabetes: impact of post-load glucose. Diabetologia. 2010;53(5):866-874.

Snell-Bergeon JK, West NA, Mayer-Davis EJ, Liese AD, Marcovina SM, D'Agostino RB Jr, Hamman RF, Dabelea D. Inflammatory markers are increased in youth with type 1 diabetes: the SEARCH Case-Control study. J Clin Endocrinol Metab. 2010;95(6):2868-2876.

Attia A, Case LD, D'Agostino R Jr, Lesser GJ, McMullen K, Naughton MJ, Rapp SR, Rosdhal R, Shaw EG. Phase II study of ginkgo biloba in irradiated brain tumor survivors: effects on quality of life (QOL), mood, and cognitive function [abstract]. J Clin Oncol. 2010;28(Suppl):e12523.

Liese AD, Nichols M, Hodo D, Mellen PB, Schulz M, Goff DC Jr, D'Agostino RB Jr. Food intake patterns associated with carotid artery atherosclerosis in the Insulin Resistance Atherosclerosis Study. Br J Nutr. 2010;103(10):1471-1479.

Lobelo F, Liese AD, Liu J, Mayer-Davis EJ, D'Agostino RB Jr, Pate RR, Hamman RF, Dabelea D. Physical activity and electronic media use in the SEARCH for Diabetes in Youth Case-Control study. Pediatrics. 2010;125(6):e1364-1371.

McCall WV, Blocker JN, D'Agostino R Jr, Kimball J, Boggs N, Lasater B, Haskett R, Krystal A, McDonald WM, Rosenquist PB. Treatment of insomnia in depressed insomniacs: effects on health-related quality of life, objective and self-reported sleep, and depression. J Clin Sleep Med. 2010;6(4):322-329.

McCall WV, Blocker JN, D'Agostino R Jr, Kimball J, Boggs N, Lasater B, Rosenquist PB. Insomnia severity is an indicator of suicidal ideation during a depression clinical trial. Sleep Med. 2010;11(9):822-827.

Lightfoot JC, D'Agostino RB Jr, Hamilton CA, Jordan J, Torti FM, Kock ND, Jordan J, Workman S, Hundley WG. Novel approach to early detection of doxorubicin cardiotoxicity by gadolinium-enhanced cardiovascular magnetic resonance imaging in an experimental model. Circ Cardiovasc Imaging. 2010;3(5):550-558.

Pinnix ZK, Miller LD, Wang W, D'Agostino R Jr, Kute T, Willingham MC, Hatcher H, Tesfay L, Sui G, Di X, Torti SV, Torti FM. Ferroportin and iron regulation in breast cancer progression and prognosis. Sci Transl Med. 2010;2(43):43ra56.

Mayer-Davis EJ, Wojcik KY, Dabelea D, D'Agostino RB, Norris JM, King I, Pihoker C. Plasma vitamin D and preservation of C-peptide in youth with recently diagnosed autoimmune positive type 1 diabetes: SEARCH Nutrition Ancillary Study [abstract]. Diabetologia. 2010;53(Suppl 1):A928.

Il'yasova D, Spasojevic I, Base K, Tolun A, Zhang HY, Wang F, Young S, Millington D, D'Agostino RB Jr, Wagenknecht LE. Systemic markers of oxidative status and the risk of type 2 diabetes [abstract]. Free Radic Biol Med. 2010;49(Suppl 1):S38.

Il'yasova D, Reihani S, Spasojevic I, Base K, Tolun A, Wang F, Young S, Millington D, D'Agostino RB Jr. Association between systemic markers of oxidative status and the risk of colorectal adenoma polyps [abstract]. Free Radic Biol Med. 2010;49(Suppl 1):S68.

Liese AD, Lawson A, Song H-R, Hibbert JD, Porter DE, Nichols M, Lamichhane AP, Dabelea D, Mayer-Davis EJ, D'Agostino RB Jr, et al. Evaluating geographic variation in type 1 and type 2 diabetes mellitus incidence in youth in four US regions. Health Place. 2010;16(3):547-556.

Twomley K, D'Agostino R Jr, Lawrence J, Melin S, Ellis LR, Stacey B, Hamilton CA, Torti F, Little W, Hundley W. Early and persistent evidence of subclinical cardiovascular injury after receipt of anthracycline chemotherapy [abstract]. Circulation. 2010;122(21 Suppl):A12766.

McCall W, Blocker JN, D'Agostino R, Kimball J, Boggs N, Lasater B, Rosenquist PB. Insomnia predicts suicidal ideation during a depression clinical trial [abstract]. Sleep. 2010;33(Abstract Suppl):A247.

Norris AM, Gentry M, Peehl DM, D'Agostino R Jr, Scarpinato KD. The elevated expression of a mismatch repair protein is a predictor for biochemical recurrence after radical prostatectomy. Cancer Epidemiol Biomarkers Prev. 2009;18(1):57-64.

Jiao Y, Wilkinson J IV, Di X, Wang W, Hatcher H, Kock ND, D'Agostino R Jr, Knovich MA, Torti FM, Torti SV. Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood. 2009;113(2):462-469.

Schwer AL, Ballonoff A, McCammon R, Rusthoven K, D'Agostino RB, Schefter TE. Survival effect of neoadjuvant radiotherapy before esophagectomy for patients with esophageal cancer: a surveillance, epidemiology, and end-results study. Int J Radiat Oncol Biol Phys. 2009;73(2):449-455.

West NA, Hamman RF, Mayer-Davis EJ, D'Agostino RB Jr, Marcovina SM, Liese AD, Zeitler PS, Daniels SR, Dabelea D. Cardiovascular risk factors among youth with and without type 2 diabetes: differences and possible mechanisms. Diabetes Care. 2009;32(1):175-180.

Mayer-Davis EJ, Bell RA, Dabelea D, D'Agostino R Jr, Imperatore G, Lawrence JM, Liu L, Marcovina S. The many faces of diabetes in American youth: type 1 and type 2 diabetes in five race and ethnic populations: the SEARCH for Diabetes in Youth Study. Diabetes Care. 2009;32(Suppl 2):S99-S101.

Mayer-Davis EJ, Beyer J, Bell RA, Dabelea D, D'Agostino R Jr, Imperatore G, Lawrence JM, Liese AD, Liu L, Marcovina S, et al. Diabetes in African American youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care. 2009;32(Suppl 2):S112-S122.

Bell RA, Mayer-Davis EJ, Beyer JW, D'Agostino RB Jr, Lawrence JM, Linder B, Liu LL, Marcovina SM, Rodriguez BL, Williams D, et al. Diabetes in non-Hispanic white youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care. 2009;32(Suppl 2):S102-S111.

Coffman LG, Parsonage D, D'Agostino RD Jr, Torti FM, Torti SV. Regulatory effects of ferritin on angiogenesis. Proc Natl Acad Sci U S A. 2009;106(2):570-575.

Dabelea D, DeGroat J, Sorrelman C, Glass M, Percy CA, Avery C, Hu D, D'Agostino RB Jr, Beyer J, Imperatore G, et al. Diabetes in Navajo youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care. 2009;32(Suppl 2):S141-S147.

McCall WV, D'Agostino RB, Kimball JN, Boggs N, Lasater B, Dunn A, Haskett RF, McDonald WM, Krystal A, Rosenquist PB. Eszopiclone at bedtime improves the quality of life in depressed insomniacs receiving fluoxetene [abstract]. Sleep. 2009;32(Abstr Suppl):A348-A349.

Guy J, Ogden L, Wadwa RP, Hamman RF, Mayer-Davis EJ, Liese AD, D'Agostino R Jr, Marcovina S, Dabelea D. Lipid and lipoprotein profiles in youth with and without type 1 diabetes: the SEARCH for Diabetes in Youth Case-Control Study. Diabetes Care. 2009;32(3):416-420.

Lawrence JM, Mayer-Davis EJ, Reynolds K, Beyer J, Pettitt DJ, D'Agostino RB Jr, Marcovina SM, Imperatore G, Hamman RF. Diabetes in Hispanic American youth: prevalence, incidence, demographics, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diabetes Care. 2009;32(Suppl 2):S123-S132.

Liese AD, Nichols M, Sun X, D'Agostino RB Jr, Haffner SM. Adherence to the DASH diet is inversely associated with incident type 2 diabetes: the Insulin Resistance Atherosclerosis Study [abstract]. Circulation. 2009;119(10):e273.

Liese AD, Bortsov A, Gunther AL, Dabelea D, Reynolds K, Standiford D, Oiu L, Williams D, D'Agostino RB Jr, Bell R, et al. Association of DASH dietary index with CVD risk factors in youth with diabetes: the SEARCH for Diabetes in Youth Study [abstract]. Circulation. 2009;119(10):e295.

Rerkpattanapipat P, D'Agostino RB Jr, Link KM, Shahar E, Lima JA, Bluemke DA, Sinha S, Herrington DM, Hundley WG. Location of arterial stiffening differs in those with impaired fasting glucose versus diabetes: implications for left ventricular hypertrophy from the Multi-Ethnic Study of Atherosclerosis. Diabetes. 2009;58(4):946-953.

MacKay MF, Haffner SM, Wagenknecht LE, D'Agostino RB Jr, Hanley AJG. Prediction of type 2 diabetes using alternate anthropometric measures in a multi-ethnic cohort: the Insulin Resistance Atherosclerosis Study. Diabetes Care. 2009;32(5):956-958.

Mayer-Davis EJ, Ma B, Lawson A, D'Agostino RB Jr, Liese AD, Bell RA, Dabelea D, Dolan L, Pettitt DJ, Rodriguez BL, et al. Cardiovascular disease risk factors in youth with type 1 and type 2 diabetes: implications of a factor analysis of clustering. Metab Syndr Relat Disord. 2009;7(2):89-96.

Dance-Barnes ST, Kock ND, Moore JE, Lin EY, Mosley LJ, D'Agostino RB Jr, McCoy TP, Townsend AJ, Miller MS. Lung tumor promotion by curcumin. Carcinogenesis. 2009;30(6):1016-1023.

Maahs DM, Hamman RF, D'Agostino R Jr, Dolan LM, Imperatore G, Lawrence JM, Marcovina SM, Mayer-Davis EJ, Pihoker C, Dabelea D. The association between adiponectin/leptin ratio and diabetes type: the SEARCH for Diabetes in Youth study. J Pediatr. 2009;155(1):133-135.

Smith AJ, Karpova Y, D'Agostino R Jr, Willingham M, Kulik G. Expression of the Bcl-2 protein BAD promotes prostate cancer growth. PLoS ONE. 2009;4(7):e6224.

Liese AD, Nichols M, Sun X, D'Agostino RB Jr, Haffner SM. Adherence to the DASH Diet is inversely associated with incidence of type 2 diabetes: the Insulin Resistance Atherosclerosis Study. Diabetes Care. 2009;32(8):1434-1436.

Aboushwareb T, Zhou G, Deng F-M, Turner C, Andersson K-E, Tar M, Zhao W, D'Agostino R Jr, Sun T-T, Christ GJ, et al. Alterations in bladder function associated with urothelial defects in uroplakin II and IIIa knockout mice. Neurourol Urodyn. 2009;28(8):1028-1033.

Ghosh S, Dutta S, Gomes E, Carroll D, D'Agostino R Jr, Olson J, Guthold M, Gmeiner WH. Increased heating efficiency and selective thermal ablation of malignant tissue with DNA-encased multiwalled carbon nanotubes. ACS Nano. 2009;3(9):2667-2673.

Chaosuwannakit N, D'Agostino R Jr, Hamilton CA, Lane KS, Ntim WO, Lawrence J, Melin SA, Ellis LR, Torti FM, Little WC, Hundley WG. Subclinical cardiovascular toxicity of anthracyclines identified with cardiovascular magnetic resonance imaging [abstract]. Circulation. 2009;120(18 Suppl):S299.

Christ GJ, Andersson K-E, Williams K, Zhao W, D'Agostino R Jr, Kaplan J, Aboushwareb T, Yoo J, Calenda G, Davies KP, et al. Smooth-muscle-specific gene transfer with the human Maxi-K channel improves erectile function and enhances sexual behavior in atherosclerotic cynomolgus monkeys. Eur Urol. 2009;56(6):1055-1066.

McCall WV, Kimball J, Boggs N, Lasater B, D'Agostino RB Jr, Rosenquist PB. Prevalence and prediction of primary sleep disorders in a clinical trial of depressed patients with insomnia. J Clin Sleep Med. 2009;5(5):454-458.

Burke A, Singh R, Kraft RA, Levi-Polyachenko N, Hatcher HC, D'Agostino R Jr, Kock ND, Carroll DL, Akman S, Torti FM, Torti SV, et al. Long-term survival following a single treatment of kidney tumors with multiwalled carbon nanotubes and near-infrared radiation. Proc Natl Acad Sci U S A. 2009;106(31):12897-902.

Moore WC, Meyers DA, Li H, D'Agostino R, Peters SP, Bleecker ER. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program [abstract]. Am J Respir Crit Care Med. 2009;179(1 Meeting Abstracts):A2522.

Kirk JK, Passmore LV, Bell RA, Venkat Narayan KM, D'Agostino RB Jr, Arcury TA, Quandt SA. Disparities in A1C levels between Hispanic and non-Hispanic white adults with diabetes. Diabetes Care. 2008;31(2):240-246.

Blish KR, Wang W, Willingham MC, Du W, Brown JC, Hawkins GA, Garvin AJ, D'Agostino RB Jr, Torti FM, Torti SV, et al. A human bone morphogenetic protein antagonist is down-regulated in renal cancer. Mol Biol Cell. 2008;19(2):457-464.

Pencina MJ, D'Agostino RB Sr, D'Agostino RB Jr, Vasan RS. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med. 2008;27(2):157-172.

Pencina MJ, D'Agostino RB Sr, D'Agostino RB Jr, Vasan RS. Comments on 'Integrated discrimination and net reclassification improvements--practical advice' [editorial]. Stat Med. 2008;27(2):207-212.

Barnes MM, Curran-Everett D, Hamman RF, Maahs D, Mayer-Davis EJ, D'Agostino RB Jr, West N, Dabelea D. Determinants of adiponectin levels in young people with type 1 diabetes. Diabet Med. 2008;25(3):365-369.

Christ GJ, Andersson K-E, Williams K, Zhao W, D'Agostino R, Kaplan J, Aboushwareb T, Yoo J, Davies K, Melman A. MAXI-K gene transfer with a smooth muscle specific promoter enhances erectile function and sexual behaviour in atherosclerotic cynomolgous monkeys [abstract]. Eur Urol. 2008;7(3 Suppl):143.

Coffman LG, Brown JC, Johnson DA, Parthasarathy N, D'Agostino RB Jr, Lively MO, Hua X, Willingham MC, Torti FM, Torti SV, et al. Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin. Am J Physiol Lung Cell Mol Physiol. 2008;294(3):L505-L515.

Mayer-Davis EJ, Dabelea D, Lamichhane AP, D'Agostino RB Jr, Liese AD, Thomas J, McKeown RE, Hamman RF. Breast-feeding and type 2 diabetes in the youth of three ethnic groups: the SEARCH for Diabetes in Youth Case-Control Study. Diabetes Care. 2008;31(3):470-475.

Greven KM, Williams DW III, Browne JD, McGuirt WF Sr, White DR, D'Agostino RB Jr. Radiographic complete response on post treatment CT imaging eliminates the need for adjuvant neck dissection after treatment for node positive head and neck cancer. Am J Clin Oncol. 2008;31(2):169-172.

Dance ST, Kock ND, Moore JE, Agostino [sic] RB Jr [D'Agostino RB Jr], Mosley LJ, Miller MS. Chemoprevention of murine lung tumor progression by sulindac [abstract]. Toxicol Sci. 2008;102(S-1 [Toxicologist]):179.

Miller MS, Dance ST, Kock ND, Moore JE, D'Agostino RB Jr, Mosley LJ, Townsend AJ. Lung tumor promotion by curcumin [abstract]. Toxicol Sci. 2008;102(S-1 [Toxicologist]):23.

Greven KM, White DR, Browne JD, Williams DW III, McGuirt WF Sr, D'Agostino RB Jr. Swallowing dysfunction is a common sequelae after chemoradiation for oropharynx carcinoma. Am J Clin Oncol. 2008;31(3):209-212.

Dance-Barnes ST, Kock ND, Floyd HS, Moore JE, Mosley LJ, D'Agostino RB Jr, Pettenati MJ, Miller MS. Effects of mutant human Ki-rasG12C gene dosage on murine lung tumorigenesis and signaling to its downstream effectors. Toxicol Appl Pharmacol. 2008;231(1):77-84.

Dabelea D, Mayer-Davis EJ, Lamichhane AP, D'Agostino RB Jr, Liese AD, Vehik KS, Narayan KMV, Zietler P, Hamman RF. Association of intrauterine exposure to maternal diabetes and obesity with type 2 diabetes in youth: the SEARCH Case-Control Study. Diabetes Care. 2008;31(7):1422-1426.

Dabelea D, West NA, Mayer-Davis EJ, D'Agostino RB Jr, Marcovina S, Liese AD, Zeitler PS, Daniels SR, Hamman RF. High prevalence of cardiovascular risk factors in youths with type 2 diabetes: the SEARCH for Diabetes in a Youth Case-Control Study [abstract]. Diabetologia. 2008;51(Suppl 1):S55.

Delo DM, Olson J, Baptista PM, D'Agostino RB Jr, Atala A, Zhu J-M, Soker S. Non-invasive longitudinal tracking of human amniotic fluid stem cells in the mouse heart. Stem Cells. 2008;17(6):1185-1194.

Powell B, D'Agostino R Jr, Levitan D, Ellis LR, Lyerly S, Skiles M, Manuel M, Harrelson R, Kimbrough C, Hurd DD. High dose cytarabine and clofarabine (HiDAC-->CLOF) in relapsed or refractory acute myeloid leukemia, a phase 2 trial [abstract]. Blood. 2008;112(11):676.

Murray CE, D'Agostino R Jr, Lesser GJ. Retreatment with a prolonged temozolomide (TMZ) dosing schedule in patients (pts) with recurrent malignant gliomas (MG) [abstract]. J Clin Oncol. 2008;26(15 Suppl Pt I):108s.

Norris AM, Woodruff RD, D'Agostino RB Jr, Clodfelter JE, Scarpinato KD. Elevated levels of the mismatch repair protein PMS2 are associated with prostate cancer. Prostate. 2007;67(2):214-225.

D'Agostino RB Jr. Discussion of: statistical and regulatory issues with the application of propensity score analysis to nonrandomized medical device clinical studies [editorial]. J Biopharm Stat. 2007;17(1):29-33.

D'Agostino RB Jr, D'Agostino RB Sr. Estimating treatment effects using observational data [editorial]. JAMA. 2007;297(3):314-316.

Liese AD, Gilliard T, Schulz M, D'Agostino RB Jr, Wolever TMS. Carbohydrate nutrition, glycaemic load, and plasma lipids: the Insulin Resistance Atherosclerosis Study. Eur Heart J. 2007;28(1):80-87.

Farmer D, Reddick B, D'Agostino R Jr, Jackson SA. Psychosocial correlates of mammography screening in older African American women. Oncol Nurs Forum. 2007;34(1):117-123.

DuRant R, Champion H, Wolfson M, Omli M, McCoy T, D'Agostino RB Jr, Wagoner K, Mitra A. Date fighting experiences among college students: are they associated with other health-risk behaviors?. J Am Coll Health. 2007;55(5):291-296.

Sedjo RL, Byers T, Levin TR, Haffner SM, Saad MF, Tooze JA, D'Agostino RB Jr. Change in body size and the risk of colorectal adenomas. Cancer Epidemiol Biomarkers Prev. 2007;16(3):526-531.

D'Agostino RB Jr. Propensity scores in cardiovascular research. Circulation. 2007;115(17):2340-2343.

D'Agostino RB Jr, D'Agostino RB Sr. Using observational data to estimate treatment effects [reply to letter]. JAMA. 2007;297(19):2079.

Torti FM, Coffman LG, Brown JC, Torti SV, Parthasarathy N, D'Agostino RB. Ferritin inhibits cleavage of high molecular weight kininogen by elastase and mast cell tryptase [abstract]. Am J Hematol. 2007;82(6):508-509.

Lakoski SG, Cushman M, Blumenthal RS, Kronmal R, Arnett D, D'Agostino RB Jr, Detrano RC, Herrington DM. Implications of C-reactive protein or coronary artery calcium score as an adjunct to global risk assessment for primary prevention of CHD. Atherosclerosis. 2007;193(2):401-407.

Berquin IM, Min Y, Wu R, Wu J, Perry D, Cline JM, Thomas MJ, Thornburg T, Kulik G, Edwards IJ, D'Agostino R Jr, Chen YQ, et al. Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids. J Clin Invest. 2007;117(7):1866-1875.

Dabelea D, Bell RA, D'Agostino RB Jr, Imperatore G, Johansen JM, Linder B, Liu LL, Loots B, Marcovina S, Mayer-Davis EJ, et al. Incidence of diabetes in youth in the United States. JAMA. 2007;297(24):2716-2724.

Wang W, Di X, D'Agostino RB Jr, Torti SV, Torti FM. Excess capacity of the iron regulatory protein system. J Biol Chem. 2007;282(34):24650-9.

Hanley AJG, Wagenknecht LE, Festa A, D'Agostino RB Jr, Haffner SM. Alanine aminotransferase and directly measured insulin sensitivity in a multiethnic cohort: the Insulin Resistance Atherosclerosis Study. Diabetes Care. 2007;30(7):1819-1827.

D'Agostino RB Jr. Overview of missing data techniques. Methods Mol Biol. 2007;404():339-352.

Mallakin A, Sugiyama T, Taneja P, Matise LA, Frazier DP, Choudhary M, Hawkins GA, D'Agostino RB Jr, Willingham MC, Inoue K. Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer. Cancer Cell. 2007;12(4):381-394.

Dabelea D, Mayer-Davis EJ, Pande A, D'Agostino RB, Liese AD, Narayan K, Hamman RF. Association of intrauterine exposure to maternal diabetes and obesity and type 2 diabetes in youth: SEARCH Case-Control (SEARCH CC) Study [abstract]. Diabetologia. 2007;50(Suppl 1):S151-S152.

Kirk JK, D'Agostino RB Jr, Bell RA, Passmore LV, Bonds DE, Karter AJ, Narayan KMV. Disparities in HbA1c levels between African-American and non-Hispanic white adults with diabetes. Diabetes Care. 2006;29(9):2130-2136.

Lakoski SG, Cushman M, Criqui M, Rundek T, Blumenthal RS, D'Agostino RB Jr, Herrington DM. Gender and C-reactive protein: data from the Multiethnic Study of Atherosclerosis (MESA) cohort. Am Heart J. 2006;152(3):593-598.

Kim PK, Ellis TL, Stieber VW, McMullen KP, Shaw EG, McCoy TP, D'Agostino RB, Bourland JD, Deguzman AF, Ekstrand KE, Raber MR, Tatter SB. Gamma Knife surgery targeting the resection cavity of brain metastasis that has progressed after whole-brain radiotherapy. J Neurosurg. 2006;105(Suppl):75-78.

Shi L, Adams MM, Long A, Carter CC, Bennett C, Sonntag WE, Nicolle MM, Robbins M, D'Agostino R Jr, Brunso-Bechtold JK. Spatial learning and memory deficits after whole-brain irradiation are associated with changes in NMDA receptor subunits in the hippocampus. Radiat Res. 2006;166(6):892-899.

Butler JM, Lally BE, D'Agostino R, Urbanic JJ, Wentworth S, Paskett E, Blackstock AW. Impact of race and marital status on survival and stage at presentation for patients with colorectal cancer: an analysis of data from the Surveillance, Epidemiology, and End-Results (SEER) program [abstract]. Int J Radiat Oncol Biol Phys. 2006;66(3 Suppl):S70.

Greven KM, Williams WD, Browne JD, McGuirt WF, D'Agostino R Jr. Complete clinical response on post treatment CT imaging eliminates the need for adjuvant neck dissection following treatment for node positive head and neck cancer [abstract]. Int J Radiat Oncol Biol Phys. 2006;66(3 Suppl):S440.

O'Brien MC, Champion H, D'Agostino RB, Martin BA, McCoy TP, Wolfson M, DuRant RH. How ready are colleges for an environmental approach that utilizes campus/community coalitions?. Int Q Community Health Educ. 2006;25(3):295-305.