Profile

Larry W. Daniel, Ph.D.Wake Forest School of Medicine

Larry W. Daniel, Ph.D.

Professor,
Redox Biology & Medicine Ctr

Contact Information

Academic: 336-713-7216 | Department: 336-716-2011

Email: ldaniel@wakehealth.edu

Education & Training

  • B.S., Western Kentucky University, 1973
  • M.S., Western Kentucky University, 1975
  • Ph.D., University of Tennessee-Knoxville, 1978
  • Fellowship, WFU School of Medicine, 1980

Memberships

  • Am Assn Of Cancer Research
  • Am Soc Of Biochem & Mol Biolog
Larry W. Daniel, Ph.D.

Larry W. Daniel, Ph.D.

Professor, Biochemistry
Redox Biology & Medicine Ctr

Research Interests

Signal Transduction; Reactive Oxygen Species; Lysophospholipids; Ovarian Neoplasms; Mitogen-Activated Protein Kinases
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Contact Information

Academic: 336-713-7216 | Department: 336-716-2011

Email: ldaniel@wakehealth.edu

Recent Publications

Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. Klomsiri C, Rogers LC, Soito L, McCauley AK, King SB, Nelson KJ, Poole LB, Daniel LW.. Free Radic Biol Med. 2014;71():49-60.

Modulation of signaling proteins by reversible cysteine modification [abstract]. Keyes JD, Nelson K, Parsonage D, Daniel L, Furdui C, Poole L.. FASEB J. 2013;27():993.3.

Localized hydrogen peroxide-dependent cysteine oxidation is required for lysophosphatidic acid signaling in ovarian and prostate cancer cells [abstract]. Daniel LW, Klomsiri C, Rogers LC, Nelson KJ, Soito L, King SB, Poole LB.. Free Radic Biol Med. 2012;53(Suppl 2):S33.

Localized hydrogen peroxide-dependent cysteine oxidation is required for lysophosphatidic acid signaling in ovarian and prostate cancer cells [abstract]. Nelson KJ, Rogers LC, Klomsiri C, Soito L, Poole LB, Daniel LW.. Free Radic Biol Med. 2011;51(Suppl 1):S137.

Use of dimedone-based chemical probes for sulfenic acid detection methods to visualize and identify labeled proteins. Nelson KJ, Klomsiri C, Codreanu SG, Soito L, Liebler DC, Rogers LC, Daniel LW, Poole LB.. Methods Enzymol. 2010;473():95-115.

Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells. Saunders JA, Rogers LC, Klomsiri C, Poole LB, Daniel LW.. Free Radic Biol Med. 2010;49(12):2058-2067.

Detection and identification of oxidative cysteine modifications in proteins involved in signal transduction pathways [abstract]. Klomsiri C, Poole LB, Nelson KJ, Rogers L, Klorig EB, Daniel LW, King SB, Furdui CM.. Free Radic Biol Med. 2009;47(Suppl 1):S17-S18.

Novel translocation responses of cytosolic phospholipase A2alpha fluorescent proteins. Wooten RE, Willingham MC, Daniel LW, Leslie CC, Rogers LC, Sergeant S, O'Flaherty JT.. Biochim Biophys Acta. 2008;1783(8):1544-1550.

Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins. Poole LB, Klomsiri C, Knaggs SA, Furdui CM, Nelson KJ, Thomas MJ, Fetrow JS, Daniel LW, King SB.. Bioconjug Chem. 2007;18(6):2004-2017.

The requirement of reversible cysteine sulfenic acid formation for T cell activation and function. Michalek RD, Nelson KJ, Holbrook BC, Yi JS, Stridiron D, Daniel LW, Fetrow JS, King SB, Poole LB, Grayson JM.. J Immunol. 2007;179(10):6456-6467.

The role of cysteine sulfenic acid formation during NF-kappa B-mediated signaling [abstract]. Nelson KJ, Klomsiri C, Rogers RL, Daniel LW, Poole LB.. Free Radic Biol Med. 2007;43(Suppl 1):S156.

Omega-3 fatty acids and cancer risk [letter]. Chen YQ, Berquin IM, Daniel LW, Edwards IJ, O'Flaherty JT, Thomas MJ, Tooze JA, Wykle B.. JAMA. 2006;296(3):282.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Biochemistry

Larry W. Daniel, Ph.D.

Larry W. Daniel, Ph.D.

Professor, Biochemistry
Redox Biology & Medicine Ctr

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