Profile

Larry W. Daniel, Ph.D.Wake Forest School of Medicine

Larry W. Daniel, Ph.D.

Professor,

Contact Information

Academic: 336-713-7216 | Department: 336-716-2011

Email: ldaniel@wakehealth.edu

Education & Training

  • B.S., Western Kentucky University , 1973
  • M.S., Western Kentucky University , 1975
  • Ph.D., University of Tennessee-Knoxville , 1978
  • Fellowship, WFU School of Medicine, 1980

Memberships

  • Am Assn Of Cancer Research
  • Am Soc Of Biochem & Mol Biolog
Larry W. Daniel, Ph.D.

Larry W. Daniel, Ph.D.

Professor, Biochemistry
Comprehensive Cancer Center

Research Interests

cancer/oncogenesis, cell growth, differentiation,d, hormones/cytokines/signalling

Contact Information

Academic: 336-713-7216 | Department: 336-716-2011

Email: ldaniel@wakehealth.edu

Recent Publications

Klomsiri C, Rogers LC, Soito L, McCauley AK, King SB, Nelson KJ, Poole LB, Daniel LW. Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. Free Radic Biol Med. 2014;71():49-60.

Keyes JD, Nelson K, Parsonage D, Daniel L, Furdui C, Poole L. Modulation of signaling proteins by reversible cysteine modification [abstract]. FASEB J. 2013;27():993.3.

Daniel LW, Klomsiri C, Rogers LC, Nelson KJ, Soito L, King SB, Poole LB. Localized hydrogen peroxide-dependent cysteine oxidation is required for lysophosphatidic acid signaling in ovarian and prostate cancer cells [abstract]. Free Radic Biol Med. 2012;53(Suppl 2):S33.

Nelson KJ, Rogers LC, Klomsiri C, Soito L, Poole LB, Daniel LW. Localized hydrogen peroxide-dependent cysteine oxidation is required for lysophosphatidic acid signaling in ovarian and prostate cancer cells [abstract]. Free Radic Biol Med. 2011;51(Suppl 1):S137.

Nelson KJ, Klomsiri C, Codreanu SG, Soito L, Liebler DC, Rogers LC, Daniel LW, Poole LB. Use of dimedone-based chemical probes for sulfenic acid detection methods to visualize and identify labeled proteins. Methods Enzymol. 2010;473():95-115.

Saunders JA, Rogers LC, Klomsiri C, Poole LB, Daniel LW. Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells. Free Radic Biol Med. 2010;49(12):2058-2067.

Klomsiri C, Poole LB, Nelson KJ, Rogers L, Klorig EB, Daniel LW, King SB, Furdui CM. Detection and identification of oxidative cysteine modifications in proteins involved in signal transduction pathways [abstract]. Free Radic Biol Med. 2009;47(Suppl 1):S17-S18.

Wooten RE, Willingham MC, Daniel LW, Leslie CC, Rogers LC, Sergeant S, O'Flaherty JT. Novel translocation responses of cytosolic phospholipase A2alpha fluorescent proteins. Biochim Biophys Acta. 2008;1783(8):1544-1550.

Poole LB, Klomsiri C, Knaggs SA, Furdui CM, Nelson KJ, Thomas MJ, Fetrow JS, Daniel LW, King SB. Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins. Bioconjug Chem. 2007;18(6):2004-2017.

Michalek RD, Nelson KJ, Holbrook BC, Yi JS, Stridiron D, Daniel LW, Fetrow JS, King SB, Poole LB, Grayson JM. The requirement of reversible cysteine sulfenic acid formation for T cell activation and function. J Immunol. 2007;179(10):6456-6467.

Nelson KJ, Klomsiri C, Rogers RL, Daniel LW, Poole LB. The role of cysteine sulfenic acid formation during NF-kappa B-mediated signaling [abstract]. Free Radic Biol Med. 2007;43(Suppl 1):S156.

Chen YQ, Berquin IM, Daniel LW, Edwards IJ, O'Flaherty JT, Thomas MJ, Tooze JA, Wykle B. Omega-3 fatty acids and cancer risk [letter]. JAMA. 2006;296(3):282.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Biochemistry

Larry W. Daniel, Ph.D.

Larry W. Daniel, Ph.D.

Professor, Biochemistry
Comprehensive Cancer Center

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