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James B. Daunais, Ph.D.Wake Forest School of Medicine

James B. Daunais, Ph.D.

Professor,

Contact Information

Academic: 336-713-7185 | Department: 336-713-7185

Email: jdaunais@wakehealth.edu

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Education & Training

  • B.S., East Carolina University, 1985
  • Ph.D., East Carolina University School of Medicine, 1995

Memberships

  • Society for Neuroscience
James B. Daunais, Ph.D.

James B. Daunais, Ph.D.

Professor, Physiology & Pharmacology

Research Interests

Ethanol; Brain; Central Nervous System Depressants; Brain Mapping; Tissue and Organ Harvesting
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Contact Information

Academic: 336-713-7185 | Department: 336-713-7185

Email: jdaunais@wakehealth.edu

Related Links

Recent Publications

Increased levels of the acetaldehyde-derived DNA adduct N2-ethyldeoxyguanosine in oral mucosa DNA from rhesus monkeys exposed to alcohol. Balbo S, Juanes RC, Khariwala S, Baker EJ, Daunais JB, Grant KA.. Mutagenesis. 2016;31(5):553-558.

Functional connectivity in frontal-striatal brain networks and cocaine self-administration in female rhesus monkeys. Murnane KS, Gopinath KS, Maltbie E, Daunais JB, Telesford QK, Howell LL.. Psychopharmacology (Berl). 2015;232(4):745-754.

The effects of chronic alcohol self-administration in nonhuman primate brain networks. Telesford QK, Laurienti PJ, Davenport AT, Friedman DP, Kraft RA, Daunais JB.. Alcohol Clin Exp Res. 2015;39(4):659-671.

Pathology of fractionated whole-brain irradiation in rhesus monkeys (Macaca mulatta). Hanbury DB, Robbins ME [deceased], Bourland JD, Wheeler KT, Peiffer AM, Mitchell EL, Daunais JB, Deadwyler SA, Cline JM.. Radiat Res. 2015;183(3):367-374.

Long term sertraline effects on neural structures in depressed and nondepressed adult female nonhuman primates. Willard SL, Uberseder B, Clark A, Daunais JB, Johnston WD, Neely D, Massey A, Williamson JD, Kraft RA, Bourland JD, Jones SR, Shively CA.. Neuropharmacology. 2015;99():369-378.

Effects of chronic alcohol consumption on neuronal function in the non-human primate BNST. Pleil KE, Helms CM, Sobus JR, Daunais JB, Grant KA, Kash TL.. Addict Biol. 2015;():.

Assessment of neuronal function in the extended amygdala of non-human primates after chronic voluntary alcohol consumption [abstract]. Pleil KE, Helms CM, Sobus J, Daunais JB, Grant KA, Kash TL.. Alcohol Clin Exp Res. 2015;39(Suppl 1):120A.

Voluntary ethanol consumption reduces GABAergic neuroactive steroid (3alpha,5alpha)3-hydroxypregnan-20-one (3alpha,5alpha-THP) in the amygdala of the cynomolgus monkey. Beattie MC, Maldonado-Devincci AM, Porcu P, O'Buckley TK, Daunais JB, Grant KA, Morrow AL.. Addict Biol. 2015;():.

Mapping optogenetic activation of the non-human primate brain using MEG [abstract]. Alberto G, Klorig D, McGowin I, Stapleton-Kotloski J, Popli G, Constantinidis C, Daunais JB, Godwin DW.. Soc Neurosci Abstr. 2015;2015(Neuroscience Meeting Planner):.

Disruption of early stage resting state activity as a function of alcohol consumption in nonhuman primates: an MEG study [abstract]. Stapleton-Kotloski JR, Rowland JA, Davenport AT, Epperly PM, Friedman DP, Godwin DW, Daunais JB.. Soc Neurosci Abstr. 2015;2015(Neuroscience Meeting Planner):.

Standardized method for the harvest of nonhuman primate tissue optimized for multiple modes of analyses. Davenport AT, Grant KA, Szeliga KT, Friedman DP, Daunais JB.. Cell Tissue Bank. 2014;15(1):99-110.

GABAergic neuroactive steroid 3alpha, 5 alpha-THP in amygdala of the cynomolgus monkey is inversely related to voluntary ethanol consumption [abstract]. Beattie MC, Maldonado-Devincci AM, Daunais JB, Grant KA Morrow AL.. Alcohol Clin Exp Res. 2014;38(Suppl 1):5A.

The monkey alcohol tissue research resource (MATRR) [abstract]. Baker E, Farro J, Gonzales S, Daunais J, Grant K.. Alcohol Clin Exp Res. 2014;38(Suppl 1):9A.

Transcriptional correlates of chronic ethanol consumption in the rhesus macaque: analyses of CEA RNA-SEQ data [abstract]. Hitzemann R, Iancu OD, Walter N, Darakjian P, McWeeney S, Searles R, Helms C, Ferguson B, Daunais J, Grant K.. Alcohol Clin Exp Res. 2014;38(Suppl 1):1A.

Monkey alcohol tissue research resource: banking tissues for alcohol research. Daunais JB, Davenport AT, Helms CM, Gonzales SW, Hemby SE, Friedman DP, Farro JP, Baker EJ, Grant KA.. Alcohol Clin Exp Res. 2014;38(7):1973-1981.

Vervet MRI atlas and label map for fully automated morphometric analyses. Maldjian JA, Daunais JB, Friedman DP, Whitlow CT.. Neuroinformatics. 2014;12(4):543-550.

Long term sertraline treatment decreases volumes of hippocampus and anterior cingulate cortex in an adult female primate model of depression [abstract]. Willard S, Johnston WD, Clark A, Uberseder B, Neely D, Massey A, Daunais J, Williamson J, Register TC, Bourland JD, Shively C.. Biol Psychiatry. 2013;73(9 Suppl):235S.

The effects of alcohol on the nonhuman primate brain: a network science approach to neuroimaging. Telesford QK, Laurienti PJ, Friedman DP, Kraft RA, Daunais JB.. Alcohol Clin Exp Res. 2013;37(11):1891-1900.

Primate cerebellar granule cells exhibit a tonic GABAAR conductance that is not affected by alcohol: a possible cellular substrate of the low level of response phenotype. Mohr C, Kolotushkina O, Kaplan JS, Welsh J, Daunais JB, Grant KA, Rossi DJ.. Front Neural Circuits. 2013;7():189.

Effects of alcohol consumption on levels of N-2-ethylidenedeoxyguanosine in DNA from oral and esophageal tissues from Rhesus monkeys [abstract]. Balbo S, Hecht SS, Baker EJ, Daunais JB, Grant KA.. Abstr Pap Am Chem Soc. 2013;246():53-TOXI.

Disruptions in serotonergic regulation of cortical glutamate release in primate insular cortex in response to chronic ethanol and nursery rearing. Alexander GM, Graef JD, Hammarback JA, Nordskog BK, Burnett EJ, Daunais JB, Bennett AJ, Friedman DP, Suomi SJ, Godwin DW.. Neuroscience. 2012;207():167-181.

Dynamic changes in the brain due to acute ethanol exposure in non-human primate brain networks [abstract]. Telesford QK, Davenport AT, Kraft RA, Laurienti PJ, Daunais JB.. Alcohol Clin Exp Res. 2012;36(Suppl 1):268A.

Chronic treatment with extended release methylphenidate does not alter dopamine systems or increase vulnerability for cocaine self-administration: a study in nonhuman primates. Gill KE, Pierre PJ, Daunais J, Bennett AJ, Martelle S, Gage HD, Swanson JM, Nader MA, Porrino LJ.. Neuropsychopharmacology. 2012;37(12):2555-2565.

Functional neuroimaging of sensory gating in vervet monkey using magnetoencephalography (MEG) [abstract]. Stapleton-Kotloski JR, Rowland JA, Godwin DW, Daunais JB.. Soc Neurosci Abstr. 2012;2012(Neuroscience Meeting Planner):.

Hippocampal volume in postmenopausal cynomolgus macaques with behavioral depression. Willard SL, Daunais JB, Cline JM, Shively CA.. Menopause. 2011;18(5):582-586.

Bidirectional plasticity in the primate inferior olive induced by chronic ethanol intoxication and sustained abstinence. Welsh JP, Han VZ, Rossi DJ, Mohr C, Odagiri M, Daunais JB, Grant KA.. Proc Natl Acad Sci U S A. 2011;108(25):10314-9.

Downregulation of SR Ca2+-ATPase as a contributing cause of impaired cardiomyocyte basal and beta-adrenergic regulation of [Ca2+]i with myocyte dysfunction in monkeys with chronic heavy alcohol consumption [abstract]. Wajih N, Cheng H-J, Zhou P, Daunais JB, Friedman DP, Little WC, Grant KA, Cheng CP.. Circulation. 2011;124(21 Suppl):A9254.

Impact of chronic ethanol self-administration on white matter in vervet monkey brain: a diffusion tensor imaging study [abstract]. Daunais JB, Davenport AT, Brunett EJ, Maxey VM, Trimnal MW, Dolson EP, Clissold KA, Kraft RA, Friedman DP.. Alcohol Clin Exp Res. 2011;35(6 Suppl):125A.

Monkey alcohol tissue research resource [abstract]. Daunais JB, Davenport AT, Hemby SE, Friedman DP, Baker EJ, Grant KA.. Alcohol Clin Exp Res. 2011;35(6 Suppl):123A.

The effects of acute and chronic ethanol exposure in nonhuman primate brain networks [abstract]. Telesford QK, Wyatt CL, Kraft RA, Friedman DP, Laurienti PJ, Daunais JB.. Alcohol Clin Exp Res. 2011;35(6 Suppl):126A.

Atlas-guided segmentation of vervet monkey brain MRI. Fedorov A, Li X, Pohl KM, Bouix S, Styner M, Addicott M, Wyatt C, Daunais JB, Wells WM, Kikinis R.. Open Neuroimag J. 2011;5(Suppl 2-M7):186-197.

Synaptic and morphological neuroadaptations in the putamen associated with long-term, relapsing alcohol drinking in primates. Cuzon Carlson VC, Seabold GK, Helms CM, Garg N, Odagiri M, Rau AR, Daunais J, Alvarez VA, Lovinger DM, Grant KA.. Neuropsychopharmacology. 2011;36(12):2513-2528.

Ethanol self-administration modulation of NMDA receptor subunit and related synaptic protein mRNA expression in prefrontal cortical fields in cynomolgus monkeys. Acosta G, Hasenkamp W, Daunais JB, Friedman DP, Grant KA, Hemby SE.. Brain Res. 2010;1318():144-154.

MRI-guided dissection of the nonhuman primate brain: a case study. Daunais JB, Kraft RA, Davenport AT, Burnett EJ, Maxey VM, Szeliga KT, Rau AR, Flory GS, Hemby SE, Friedman DP, et al.. Methods. 2010;50(3):199-204.

Up-regulation and functional effect of cardiac beta(3)-adrenoreceptors in alcoholic monkeys. Cheng H-J, Grant KA, Han Q-H, Daunais JB, Friedman DP, Masutani S, Little WC, Cheng C-P.. Alcohol Clin Exp Res. 2010;34(7):1171-1181.

Magnetic resonance imaging of whole, anterior and posterior hippocampal volumes in behaviorally depressed cynomolgus macaques [abstract]. Willard SL, Daunais JB, Shively CA.. Biol Psychiatry. 2010;67(9 Suppl):52S.

DiOLISTIC labeling of neurons from rodent and non-human primate brain slices [video article]. Seabold GK, Daunais JB, Rau A, Grant KA, Alvarez VA.. J Vis Exp. 2010;(41):2081.

Disruptions in serotonergic regulation of cortical glutamate release in primate insular cortex in response to chronic ethanol and early life stress [abstract]. Graef JD, Alexander GM, Hammarback JA, Nordskog BK, Burnett EJ, Daunais JB, Friedman DP, Godwin DW.. Alcohol Clin Exp Res. 2010;34(6 Suppl 2):28A.

Of mice and monkeys--expression networks correlating with ethanol drinking behavior across species [abstract]. Farris S, Bruce N, Wolstenholme JT, Daunais JB, Rau A, Keily C, Grant KA, Miles MF.. Alcohol Clin Exp Res. 2010;34(6 Suppl 2):296A.

Primate cerebellar granule cells exhibit a tonic GABA(A) conductance that is not affected by alcohol [abstract]. Rossi DJ, Grant K, Daunais J, Rau A, Odagiri M, Mohr C.. Alcohol Clin Exp Res. 2010;34(6 Suppl 2):269A.

Gene expression pattern changes in monkey prefrontal cortex following chronic ethanol self-administration [abstract]. Bruce NA, Wolstenholme JT, Daunais JB, Rau A, Keily C, Grant KA, Miles MF.. Alcohol Clin Exp Res. 2009;33(6 Special Issue):203A.

Effect of chronic ethanol on 5HT1(A) densities and serotonin transporter levels in the dorsal raphe of mother-reared vs nursery-reared macaques [abstract]. Friedman DP, Dolson EP, Maxey VM, Burnett EG [sic] [Burnett EJ], Daunais JB, Davenport AT.. Alcohol Clin Exp Res. 2009;33(6 Special Issue):23A.

A MEG investigation of somatosensory processing in the rhesus monkey. Wilson TW, Godwin DW, Czoty PW, Nader MA, Kraft RA, Buchheimer NC, Daunais JB.. Neuroimage. 2009;46(4):998-1003.

Functional significance of cardiac beta3 adrenergic receptors in alcoholic cardiomyopathy [abstract]. Cheng C-P, Cheng H-J, Masutani S, Hundley WG, Daunais JB, Friedman DP, Grant KA.. J Card Fail. 2009;15(Suppl 6):S42.

The effects of ethanol consumption on vasculogenesis potential in nonhuman primates. Williams JK, Baptista PM, Daunais JB, Szeliga KT, Friedman DP, Soker S.. Alcohol Clin Exp Res. 2008;32(1):155-161.

Effect of chronic ethanol on 5HT1A densities and serotonin transporter levels in the prefrontal cortex of mother-reared vs nursery-reared macaques [abstract]. Davenport AT, Maxey VM, Daunais JB, Friedman DP.. Alcohol Clin Exp Res. 2008;32(Suppl 1):34A.

A neurochemical comparison of striatal dopamine function in drinking monkeys [abstract]. Mathews TA, Brookshire BR, Budygin EA, Daunais JB, Friedman DP, Jones SR.. Alcohol Clin Exp Res. 2008;32(6 Suppl 1):35A.

Changes in amygdala volume associated with early life stress in rhesus macaques (Macaca mulatta) [abstract]. Burnett EJ, Friedman DP, Daunais JB.. Soc Neurosci Abstr. 2008;2008(Neuroscience Meeting Planner):.

MRI assessment of chronic antipsychotic administration in rhesus monkeys [abstract]. Hemby SE, Hanlon CA, Horman B, Sikoski P, Daunais J, Kraft R, Porrino LJ.. Soc Neurosci Abstr. 2008;2008(Neuroscience Meeting Planner):.

Ethanol self-administration and alterations in the livers of the cynomolgus monkey, Macaca fascicularis. Ivester P, Roberts LJ II, Young T, Vivian J, Lees C, Young J, Daunais J, Friedman D, Grant KA, Cunningham C, et al.. Alcohol Clin Exp Res. 2007;31(1):144-155.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

James B. Daunais, Ph.D.

James B. Daunais, Ph.D.

Professor, Physiology & Pharmacology

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