Profile

James B. Daunais, Ph.D.Wake Forest School of Medicine

James B. Daunais, Ph.D.

Associate Professor,


Contact Information

Academic: 336-713-7185 | Department: 336-713-7185

Email: jdaunais@wakehealth.edu

Education & Training

  • B.S., East Carolina University , 1985
  • Ph.D., East Carolina University School of Medicine , 1995

Memberships

  • Society for Neuroscience
James B. Daunais, Ph.D.

James B. Daunais, Ph.D.

Associate Professor, Physiology & Pharmacology
Center for Comparative Medicine Research
Translational Science Institute

Research Interests

cross(mult/tnslat/inter)discip, genomics and proteomics, neurosciences/behavior, substance abuse

Contact Information

Academic: 336-713-7185 | Department: 336-713-7185

Email: jdaunais@wakehealth.edu

Recent Publications

Davenport AT, Grant KA, Szeliga KT, Friedman DP, Daunais JB. Standardized method for the harvest of nonhuman primate tissue optimized for multiple modes of analyses. Cell Tissue Bank. 2014;15(1):99-110.

Beattie MC, Maldonado-Devincci AM, Daunais JB, Grant KA Morrow AL. GABAergic neuroactive steroid 3alpha, 5 alpha-THP in amygdala of the cynomolgus monkey is inversely related to voluntary ethanol consumption [abstract]. Alcohol Clin Exp Res. 2014;38(Suppl 1):5A.

Baker E, Farro J, Gonzales S, Daunais J, Grant K. The monkey alcohol tissue research resource (MATRR) [abstract]. Alcohol Clin Exp Res. 2014;38(Suppl 1):9A.

Hitzemann R, Iancu OD, Walter N, Darakjian P, McWeeney S, Searles R, Helms C, Ferguson B, Daunais J, Grant K. Transcriptional correlates of chronic ethanol consumption in the rhesus macaque: analyses of CEA RNA-SEQ data [abstract]. Alcohol Clin Exp Res. 2014;38(Suppl 1):1A.

Daunais JB, Davenport AT, Helms CM, Gonzales SW, Hemby SE, Friedman DP, Farro JP, Baker EJ, Grant KA. Monkey alcohol tissue research resource: banking tissues for alcohol research. Alcohol Clin Exp Res. 2014;38(7):1973-1981.

Maldjian JA, Daunais JB, Friedman DP, Whitlow CT. Vervet MRI atlas and label map for fully automated morphometric analyses. Neuroinformatics. 2014;12(4):543-550.

Willard S, Johnston WD, Clark A, Uberseder B, Neely D, Massey A, Daunais J, Williamson J, Register TC, Bourland JD, Shively C. Long term sertraline treatment decreases volumes of hippocampus and anterior cingulate cortex in an adult female primate model of depression [abstract]. Biol Psychiatry. 2013;73(9 Suppl):235S.

Telesford QK, Laurienti PJ, Friedman DP, Kraft RA, Daunais JB. The effects of alcohol on the nonhuman primate brain: a network science approach to neuroimaging. Alcohol Clin Exp Res. 2013;37(11):1891-1900.

Mohr C, Kolotushkina O, Kaplan JS, Welsh J, Daunais JB, Grant KA, Rossi DJ. Primate cerebellar granule cells exhibit a tonic GABAAR conductance that is not affected by alcohol: a possible cellular substrate of the low level of response phenotype. Front Neural Circuits. 2013;7():189.

Balbo S, Hecht SS, Baker EJ, Daunais JB, Grant KA. Effects of alcohol consumption on levels of N-2-ethylidenedeoxyguanosine in DNA from oral and esophageal tissues from Rhesus monkeys [abstract]. Abstr Pap Am Chem Soc. 2013;246():53-TOXI.

Alexander GM, Graef JD, Hammarback JA, Nordskog BK, Burnett EJ, Daunais JB, Bennett AJ, Friedman DP, Suomi SJ, Godwin DW. Disruptions in serotonergic regulation of cortical glutamate release in primate insular cortex in response to chronic ethanol and nursery rearing. Neuroscience. 2012;207():167-181.

Telesford QK, Davenport AT, Kraft RA, Laurienti PJ, Daunais JB. Dynamic changes in the brain due to acute ethanol exposure in non-human primate brain networks [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 1):268A.

Gill KE, Pierre PJ, Daunais J, Bennett AJ, Martelle S, Gage HD, Swanson JM, Nader MA, Porrino LJ. Chronic treatment with extended release methylphenidate does not alter dopamine systems or increase vulnerability for cocaine self-administration: a study in nonhuman primates. Neuropsychopharmacology. 2012;37(12):2555-2565.

Stapleton-Kotloski JR, Rowland JA, Godwin DW, Daunais JB. Functional neuroimaging of sensory gating in vervet monkey using magnetoencephalography (MEG) [abstract]. Soc Neurosci Abstr. 2012;2012(Neuroscience Meeting Planner):.

Willard SL, Daunais JB, Cline JM, Shively CA. Hippocampal volume in postmenopausal cynomolgus macaques with behavioral depression. Menopause. 2011;18(5):582-586.

Welsh JP, Han VZ, Rossi DJ, Mohr C, Odagiri M, Daunais JB, Grant KA. Bidirectional plasticity in the primate inferior olive induced by chronic ethanol intoxication and sustained abstinence. Proc Natl Acad Sci U S A. 2011;108(25):10314-9.

Wajih N, Cheng H-J, Zhou P, Daunais JB, Friedman DP, Little WC, Grant KA, Cheng CP. Downregulation of SR Ca2+-ATPase as a contributing cause of impaired cardiomyocyte basal and beta-adrenergic regulation of [Ca2+]i with myocyte dysfunction in monkeys with chronic heavy alcohol consumption [abstract]. Circulation. 2011;124(21 Suppl):A9254.

Daunais JB, Davenport AT, Brunett EJ, Maxey VM, Trimnal MW, Dolson EP, Clissold KA, Kraft RA, Friedman DP. Impact of chronic ethanol self-administration on white matter in vervet monkey brain: a diffusion tensor imaging study [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):125A.

Daunais JB, Davenport AT, Hemby SE, Friedman DP, Baker EJ, Grant KA. Monkey alcohol tissue research resource [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):123A.

Telesford QK, Wyatt CL, Kraft RA, Friedman DP, Laurienti PJ, Daunais JB. The effects of acute and chronic ethanol exposure in nonhuman primate brain networks [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):126A.

Fedorov A, Li X, Pohl KM, Bouix S, Styner M, Addicott M, Wyatt C, Daunais JB, Wells WM, Kikinis R. Atlas-guided segmentation of vervet monkey brain MRI. Open Neuroimag J. 2011;5(Suppl 2-M7):186-197.

Cuzon Carlson VC, Seabold GK, Helms CM, Garg N, Odagiri M, Rau AR, Daunais J, Alvarez VA, Lovinger DM, Grant KA. Synaptic and morphological neuroadaptations in the putamen associated with long-term, relapsing alcohol drinking in primates. Neuropsychopharmacology. 2011;36(12):2513-2528.


Daunais JB, Kraft RA, Davenport AT, Burnett EJ, Maxey VM, Szeliga KT, Rau AR, Flory GS, Hemby SE, Friedman DP, et al. MRI-guided dissection of the nonhuman primate brain: a case study. Methods. 2010;50(3):199-204.

Cheng H-J, Grant KA, Han Q-H, Daunais JB, Friedman DP, Masutani S, Little WC, Cheng C-P. Up-regulation and functional effect of cardiac beta(3)-adrenoreceptors in alcoholic monkeys. Alcohol Clin Exp Res. 2010;34(7):1171-1181.

Willard SL, Daunais JB, Shively CA. Magnetic resonance imaging of whole, anterior and posterior hippocampal volumes in behaviorally depressed cynomolgus macaques [abstract]. Biol Psychiatry. 2010;67(9 Suppl):52S.

Seabold GK, Daunais JB, Rau A, Grant KA, Alvarez VA. DiOLISTIC labeling of neurons from rodent and non-human primate brain slices [video article]. J Vis Exp. 2010;(41):2081.

Graef JD, Alexander GM, Hammarback JA, Nordskog BK, Burnett EJ, Daunais JB, Friedman DP, Godwin DW. Disruptions in serotonergic regulation of cortical glutamate release in primate insular cortex in response to chronic ethanol and early life stress [abstract]. Alcohol Clin Exp Res. 2010;34(6 Suppl 2):28A.

Farris S, Bruce N, Wolstenholme JT, Daunais JB, Rau A, Keily C, Grant KA, Miles MF. Of mice and monkeys--expression networks correlating with ethanol drinking behavior across species [abstract]. Alcohol Clin Exp Res. 2010;34(6 Suppl 2):296A.

Rossi DJ, Grant K, Daunais J, Rau A, Odagiri M, Mohr C. Primate cerebellar granule cells exhibit a tonic GABA(A) conductance that is not affected by alcohol [abstract]. Alcohol Clin Exp Res. 2010;34(6 Suppl 2):269A.

Bruce NA, Wolstenholme JT, Daunais JB, Rau A, Keily C, Grant KA, Miles MF. Gene expression pattern changes in monkey prefrontal cortex following chronic ethanol self-administration [abstract]. Alcohol Clin Exp Res. 2009;33(6 Special Issue):203A.

Friedman DP, Dolson EP, Maxey VM, Burnett EG [sic] [Burnett EJ], Daunais JB, Davenport AT. Effect of chronic ethanol on 5HT1(A) densities and serotonin transporter levels in the dorsal raphe of mother-reared vs nursery-reared macaques [abstract]. Alcohol Clin Exp Res. 2009;33(6 Special Issue):23A.

Wilson TW, Godwin DW, Czoty PW, Nader MA, Kraft RA, Buchheimer NC, Daunais JB. A MEG investigation of somatosensory processing in the rhesus monkey. Neuroimage. 2009;46(4):998-1003.

Cheng C-P, Cheng H-J, Masutani S, Hundley WG, Daunais JB, Friedman DP, Grant KA. Functional significance of cardiac beta3 adrenergic receptors in alcoholic cardiomyopathy [abstract]. J Card Fail. 2009;15(Suppl 6):S42.

Williams JK, Baptista PM, Daunais JB, Szeliga KT, Friedman DP, Soker S. The effects of ethanol consumption on vasculogenesis potential in nonhuman primates. Alcohol Clin Exp Res. 2008;32(1):155-161.

Davenport AT, Maxey VM, Daunais JB, Friedman DP. Effect of chronic ethanol on 5HT1A densities and serotonin transporter levels in the prefrontal cortex of mother-reared vs nursery-reared macaques [abstract]. Alcohol Clin Exp Res. 2008;32(Suppl 1):34A.

Mathews TA, Brookshire BR, Budygin EA, Daunais JB, Friedman DP, Jones SR. A neurochemical comparison of striatal dopamine function in drinking monkeys [abstract]. Alcohol Clin Exp Res. 2008;32(6 Suppl 1):35A.

Burnett EJ, Friedman DP, Daunais JB. Changes in amygdala volume associated with early life stress in rhesus macaques (Macaca mulatta) [abstract]. Soc Neurosci Abstr. 2008;2008(Neuroscience Meeting Planner):.

Hemby SE, Hanlon CA, Horman B, Sikoski P, Daunais J, Kraft R, Porrino LJ. MRI assessment of chronic antipsychotic administration in rhesus monkeys [abstract]. Soc Neurosci Abstr. 2008;2008(Neuroscience Meeting Planner):.

Ivester P, Roberts LJ II, Young T, Vivian J, Lees C, Young J, Daunais J, Friedman D, Grant KA, Cunningham C, et al. Ethanol self-administration and alterations in the livers of the cynomolgus monkey, Macaca fascicularis. Alcohol Clin Exp Res. 2007;31(1):144-155.

Anderson NJ, Daunais JB, Friedman DP, Grant KA, McCool BA. Long-term ethanol self-administration by the nonhuman primate, Macaca fascicularis, decreases the benzodiazepine sensitivity of amygdala GABA(A) receptors. Alcohol Clin Exp Res. 2007;31(6):1061-1070.

Daunais JB, Liu W, Wyatt CL, Szeliga KT, Buchheimer NC, Gage HD, Kraft RA, Friedman DP. Ethanol-induced volume changes in Macaque brain [abstract]. Alcohol Clin Exp Res. 2007;31(6 Suppl):147A.

Davenport AT, Szeliga KT, Moser VM, Daunais JB, Friedman DP. Effect of chronic ethanol on 5HT1A and serotonin transporter densities in the hippocampus and raphe of mother-reared vs peer-reared macaques [abstract]. Alcohol Clin Exp Res. 2007;31(Suppl 2):208A.

Carden WB, Alexander GM, Friedman DP, Daunais JB, Grant KA, Mu J, Godwin DW. Chronic ethanol drinking reduces native T-type calcium current in the thalamus of nonhuman primates. Brain Res. 2006;1089():92-100.

Alexander GM, Carden WB, Mu J, Kurukulasuriya NC, McCool BA, Nordskog BK, Friedman DP, Daunais JB, Grant KA, Godwin DW. The native T-type calcium current in relay neurons of the primate thalamus. Neuroscience. 2006;141(1):453-461.

Deadwyler SA, Porrino LJ, Daunais JB, Miller M, Hanlon CA, Morgan AR, Gill KE, Long J, Ramirez S, Todd M, Hampson RE. Evidence for the differential effects of modafinil and the ampakine CX717 on task-related brain glucose metabolism in sleep-deprived monkeys [abstract]. Soc Neurosci Abstr. 2006;2006(Abstr Viewer):.

Hampson R, Porrino LJ, Daunais JB, Miller M, Hanlon CA, Morgan AR, Gill KE, Long J, Ramirez S, Todd M, Deadwyler SA. Sleep deprivation disrupts brain glucose utilization and performance on high vs. low cognitive load trials during a delayed-match-to-sample (DMS) task in nonhuman primates [abstract]. Soc Neurosci Abstr. 2006;2006(Abstr Viewer):.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Physiology & Pharmacology

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