Profile

Rajendar Deora, Ph.D.Wake Forest School of Medicine

Rajendar Deora, Ph.D.

Associate Professor,

Contact Information

Academic: 336-716-1124 | Department: 336-716-2011

Email: rdeora@wakehealth.edu

Education & Training

  • B.Sc., Calcutta University Medical College-India, 1989
  • M.Sc., Calcutta University Natl Medical Institute-India, 1991
  • Ph.D., University of Illinois-Chicago, 1997
  • Fellowship, University of California Sch o, 2003
Rajendar Deora, Ph.D.

Rajendar Deora, Ph.D.

Associate Professor, Microbiology & Immunology

Research Interests

Bordetella bronchiseptica; Biofilms; Bacterial Proteins; Gene Expression Regulation, Bacterial; Bacterial Outer Membrane Proteins
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Contact Information

Academic: 336-716-1124 | Department: 336-716-2011

Email: rdeora@wakehealth.edu

Recent Publications

Bordetella biofilms: a lifestyle leading to persistent infections. Cattelan N, Dubey P, Arnal L, Yantorno OM, Deora R.. Pathog Dis. 2016;74(1):.

The protein BpsB is a poly-beta-1,6-N-acetyl-D-glucosamine deacetylase required for biofilm formation in Bordetella bronchiseptica. Little DJ, Milek S, Bamford NC, Ganguly T, DiFrancesco BR, Nitz M, Deora R, Howell PL.. J Biol Chem. 2015;290(37):22827-40.

Comparative analyses of a cystic fibrosis isolate of bordetella bronchiseptica reveal differences in important pathogenic phenotypes. Sukumar N, Nicholson TL, Conover MS, Ganguly T, Deora R.. Infect Immun. 2014;82(4):1627-1637.

The Bordetella pertussis Bps polysaccharide enhances lung colonization by conferring protection from complement-mediated killing. Ganguly T, Johnson JB, Kock ND, Parks GD, Deora R.. Cell Microbiol. 2014;16(7):1105-1118.

The genetic composition of Oxalobacter formigenes and its relationship to colonization and calcium oxalate stone disease. Knight J, Deora R, Assimos DG, Holmes RP.. Urolithiasis. 2013;41(3):187-196.

D-alanine modification of a protease-susceptible outer membrane component by the Bordetella pertussis dra locus promotes resistance to antimicrobial peptides and polymorphonuclear leukocyte-mediated killing. Taneja NK, Ganguly T, Bakaletz LO, Nelson KJ, Dubey P, Poole LB, Deora R.. J Bacteriol. 2013;195(22):5102-5111.

BpsR modulates Bordetella biofilm formation by negatively regulating the expression of the Bps polysaccharide. Conover MS, Redfern CJ, Ganguly T, Sukumar N, Sloan G, Mishra M, Deora R.. J Bacteriol. 2012;194(2):233-242.

Bordetella bronchiseptica in a paediatric cystic fibrosis patient: possible transmission from a household cat. Register KB, Sukumar N, Palavecino EL, Rubin BK, Deora R.. Zoonoses Public Health. 2012;59(4):246-250.

Positive and negative regulation of prostate stem cell antigen expression by Yin Yang 1 in prostate epithelial cell lines. Tang S, Mishra M, Frazier DP, Moore ML, Inoue K, Deora R, Sui G, Dubey P.. PLoS ONE. 2012;7(4):e35570.

Transcriptome profiling reveals stage-specific production and requirement of flagella during biofilm development in Bordetella bronchiseptica. Nicholson TL, Conover MS, Deora R.. PLoS One. 2012;7(11):e49166.

Extracellular DNA is essential for maintaining Bordetella biofilm integrity on abiotic surfaces and in the upper respiratory tract of mice. Conover MS, Mishra M, Deora R.. PLoS ONE. 2011;6(2):e16861.

FHA-mediated cell-substrate and cell-cell adhesions are critical for Bordetella pertussis biofilm formation on abiotic surfaces and in the mouse nose and the trachea. Serra DO, Conover MS, Arnal L, Sloan GP, Rodriguez ME, Yantorno OM, Deora R.. PLoS ONE. 2011;6(12):e28811.

Cross-species protection mediated by a Bordetella bronchiseptica strain lacking antigenic homologs present in acellular pertussis vaccines. Sukumar N, Sloan GP, Conover MS, Love CF, Mattoo S, Kock ND, Deora R.. Infect Immun. 2010;78(5):2008-2016.

The Bps polysaccharide of Bordetella pertussis promotes colonization and biofilm formation in the nose by functioning as an adhesin. Conover MS, Sloan GP, Love CF, Sukumar N, Deora R.. Mol Microbiol. 2010;77(6):1439-1455.

AmrZ beta-sheet residues are essential for DNA binding and transcriptional control of Pseudomonas aeruginosa virulence genes. Waligora EA, Ramsey DM, Pryor EE Jr, Lu H, Hollis T, Sloan GP, Deora R, Wozniak DJ.. J Bacteriol. 2010;192(20):5390-5401.

Active and passive immunization with Bordetella colonization factor A protects mice against respiratory challenge with Bordetella bronchiseptica. Sukumar N, Love CF, Conover MS, Kock ND, Dubey P, Deora R.. Infect Immun. 2009;77(2):885-895.

Polysaccharides cellulose, poly-beta-1,6-N-acetyl-D-glucosamine, and colanic acid are required for optimal binding of Escherichia coli O157:H7 strains to alfalfa sprouts and K12 strains to plastic but not for binding to epithelial cells. Matthysse AG, Deora R, Mishra M, Torres AG.. Appl Environ Microbiol. 2008;74(8):2384-2390.

Role of a putative polysaccharide locus in Bordetella biofilm development. Parise G, Mishra M, Itoh Y, Romeo T, Deora R.. J Bacteriol. 2007;189(3):750-760.

Differential Bvg phase-dependent regulation and combinatorial role in pathogenesis of two Bordetella paralogs, BipA and BcfA. Sukumar N, Mishra M, Sloan GP, Ogi T, Deora R.. J Bacteriol. 2007;189(10):3695-3704.

Inhibition of Pseudomonas aeruginosa biofilm formation with bromoageliferin analogues. Huigens RW III, Richards JJ, Parise G, Ballard TE, Zeng W, Deora R, Melander C.. J Am Chem Soc. 2007;129(22):6966-6967.

The Bordetella Bps polysaccharide is critical for biofilm development in the mouse respiratory tract. Sloan GP, Love CF, Sukumar N, Mishra M, Deora R.. J Bacteriol. 2007;189(22):8270-8276.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Microbiology & Immunology

Rajendar Deora, Ph.D.

Rajendar Deora, Ph.D.

Associate Professor, Microbiology & Immunology

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