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Jingzhong Ding, Ph.D.Wake Forest School of Medicine

Jingzhong Ding, Ph.D.

Associate Professor,



Contact Information

Academic: 336-713-8558 | Department: 336-713-8570

Education & Training

  • M.D., Bengbu Medical College in China, 1991
  • Ph.D., Sch Hyg & PH,Johns Hopkins U, 2002
Jingzhong Ding, Ph.D.

Jingzhong Ding, Ph.D.

Associate Professor, Gerontology and Geriatric Medicine
Sticht Center on Aging
Center for Comparative Medicine Research
Epidemiology & Prevention

Research Interests

aging, atherosclerosis/thrombosis, diabetes, genetics/genome, obesity, vascular diseases

Contact Information

Academic: 336-713-8558 | Department: 336-713-8570

Recent Publications

Gorski M, Tin A, Garnaas M, McMahon GM, Chu AY, Tayo BO, Pattaro C, Teumer A, Chasman DI, Chalmers J, Hamet P, Tremblay J, Woodward M, Aspelund T, Eiriksdottir G, Gudnason V, Harris TB, Launer LJ, Smith AV, Mitchell BD, O'Connell JR, Shuldiner AR,. Genome-wide association study of kidney function decline in individuals of European descent. Kidney Int. 2015;87(5):1017-1029.

Ong KL, Ding J, McClelland RL, Cheung BM, Criqui MH, Barter PJ, Rye KA, Allison MA. Relationship of pericardial fat with biomarkers of inflammation and hemostasis, and cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2015;239(2):386-392.

Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ,. GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Mol Psychiatry. 2015;():.

Reynolds LM, Ding J, Taylor JR, Lohman K, Soranzo N, de la Fuente A, Liu TF, Johnson C, Barr RG, Register TC, Donohue KM, Talor MV, Cihakova D, Gu C, Divers J, Siscovick D, Burke G, Post W, Shea S, Jacobs DR Jr, Hoeschele I, McCall CE,. Transcriptomic profiles of aging in purified human immune cells. BMC Genomics. 2015;16(1):333.

Ong KL, Ding J, McClelland RL, Cheung BM, Criqui MH, Barter PJ, Rye KA, Allison MA. Relationship of pericardial fat with lipoprotein distribution: the Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 2015;241(2):664-670.

Tison GH, Blaha MJ, Nasir K, Blumenthal RS, Szklo M, Ding J, Budoff MJ. Relation of anthropometric obesity and computed tomography measured nonalcoholic fatty liver disease (from the Multiethnic Study of Atherosclerosis). Am J Cardiol. 2015;():.

Williamson JD, Launer LJ, Bryan RN, Coker LH, Lazar RM, Gerstein HC, Murray AM, Sullivan MD, Horowitz KR, Ding J, Marcovina S, Lovato L, Lovato J, Margolis KL, Davatzikos C, Barzilay J, Ginsberg HN, Linz PE, Miller ME. Cognitive function and brain structure in persons with type 2 diabetes mellitus after intensive lowering of blood pressure and lipid levels: a randomized clinical trial. JAMA Intern Med. 2014;174(3):324-333.

Merikangas KR, Cui L, Heaton L, Nakamura E, Roca C, Ding J, Qin H, Guo W, Shugart YY, Zarate C, Angst J. Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders. Mol Psychiatry. 2014;19(2):214-219.

Brinkley TE, Leng X, Chughtai HL, Nicklas BJ, Kritchevsky SB, Ding J, Kitzman DW, Hundley WG. Periaortic fat and cardiovascular risk: a comparison of high-risk older adults and age-matched healthy controls. Int J Obes (Lond). 2014;38(11):1397-1402.

Liu CK, Leng X, Hsu FC, Kritchevsky SB, Ding J, Earnest CP, Ferrucci L, Goodpaster BH, Guralnik JM, Lenchik L, Pahor M, Fielding RA. The impact of sarcopenia on a physical activity intervention: the Lifestyle Interventions and Independence for Elders Pilot Study (LIFE-P). J Nutr Health Aging. 2014;18(1):59-64.

Yeboah J, Carr JJ, Terry JG, Ding J, Zeb I, Liu S, Nasir K, Post W, Blumenthal RS, Budoff MJ. Computed tomography-derived cardiovascular risk markers, incident cardiovascular events, and all-cause mortality in nondiabetics: the Multi-Ethnic Study of Atherosclerosis. Eur J Prev Cardiol. 2014;21(10):1233-1241.

Hugenschmidt CE, Lovato JF, Ambrosius WT, Bryan RN, Gerstein HC, Horowitz KR, Launer LJ, Lazar RM, Murray AM, Chew EY, Danis RP, Williamson JD, Miller ME, Ding J. The cross-sectional and longitudinal associations of diabetic retinopathy with cognitive function and brain MRI findings: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Diabetes Care. 2014;37(12):3244-3252.

Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, Wiggins KL, Avery CL, Griffin P, Feng Q, Taylor KD, Li G, Evans DS, Smith AV, de Keyser CE, Johnson AD, de Craen AJ, Stott DJ, Buckley BM,. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun. 2014;5():5068.

Reynolds LM, Taylor JR, Ding J, Lohman K, Johnson C, Siscovick D, Burke G, Post W, Shea S, Jacobs DR Jr, Stunnenberg H, Kritchevsky SB, Hoeschele I, McCall CE, Herrington DM, Tracy RP, Liu Y. Age-related variations in the methylome associated with gene expression in human monocytes and T cells. Nat Commun. 2014;5():5366.

Shah RV, Murthy VL, Abbasi SA, Blankstein R, Kwong RY, Goldfine AB, Jerosch-Herold M, Lima JA, Ding J, Allison MA. Visceral adiposity and the risk of metabolic syndrome across body mass index: the MESA study. JACC Cardiovasc Imaging. 2014;7(12):1221-1235.

Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D,. A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013;73(7):667-678.

McClain J, Hsu F, Brown E, Burke G, Carr J, Harris T, Kritchevsky S, Szklo M, Tracy R, Ding J. Pericardial adipose tissue and coronary artery calcification in the Multi-ethnic Study of Atherosclerosis (MESA. Obesity (Silver Spring). 2013;21(5):1056-1063.

Monda KL, Chen GK, Taylor KC, Ng MCY, Liu Y, Freedman BI, Howard TD, Langefeld CD, Lohman K, Palmer ND, Shriner DA, Burke G, Ding J, et al. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013;45(6):690-696.

Feng X, Todd T, Lintzenich CR, Ding J, Carr JJ, Ge Y, Browne JD, Kritchevsky SB, Butler SG. Aging-related geniohyoid muscle atrophy is related to aspiration status in healthy older adults. J Gerontol A Biol Sci Med Sci. 2013;68(7):853-860.

Liu CT, Monda KL, Taylor KC, Lange L, Demerath EW, Palmas W, Wojczynski MK, Ellis JC, Vitolins MZ, Liu S, Papanicolaou GJ, Irvin MR, Xue L, Griffin PJ, Nalls MA, Adeyemo A, Liu J, Li G, Ruiz-Narvaez EA, Chen WM, Chen F,. Genome-wide association of body fat distribution in african ancestry populations suggests new Loci. PLoS Genet. 2013;9(8):e1003681.

Laek B, Szklo M, McClelland RL, Ding J, Tsai MY, Bluemke DA, Tracy R, Matsushita K. The prospective association of Chlamydia pneumoniae and four other pathogens with development of coronary artery calcium: the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2013;230(2):268-274.

O'Seaghdha CM, Wu H, Yang Q, Kapur K, Guessous I, Zuber AM, Kottgen A, Stoudmann C, Teumer A, Kutalik Z, Mangino M, Dehghan A, Zhang W, Eiriksdottir G, Li G, Tanaka T, Portas L, Lopez LM, Hayward C, Lohman K,. Meta-analysis of genome-wide association studies identifies six new loci for serum calcium concentrations. PLoS Genet. 2013;9(9):e1003796.

Liu Y, Ding J, Reynolds LM, Lohman K, Register TC, De La Fuente A, Howard TD, Hawkins GA, Cui W, Morris J, Smith SG, Barr RG, Kaufman JD, Burke GL, Post W, Shea S, McCall CE, Siscovick D, Jacobs DR Jr, Tracy RP,. Methylomics of gene expression in human monocytes. Hum Mol Genet. 2013;22(24):5065-5074.

Murphy RA, Schairer C, Gierach GL, Byrne C, Sherman ME, Register TC, Ding J, Kritchevsky SB, Harris TB. Beyond breast cancer: mammographic features and mortality risk in a population of healthy women. PLoS One. 2013;8(10):e78722.

Zeb I, Katz R, Nasir K, Ding J, Rezaeian P, Budoff MJ. Relation of nonalcoholic fatty liver disease to the metabolic syndrome: the Multi-Ethnic Study of Atherosclerosis. J Cardiovasc Comput Tomogr. 2013;7(5):311-318.

Parsa A, Fuchsberger C, Kottgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, Chen MH, Tin A, Kim YJ, Taliun D, Li M, Feitosa M, Gorski M, Yang Q, Hundertmark C, Foster MC, Glazer N, Isaacs A,. Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol. 2013;24(12):2105-2117.

Franceschini N, Fox E, Zhang Z, Edwards TL, Nalls MA, Sung YJ, Tayo BO, Sun YV, Gottesman O, Adeyemo A, Johnson AD, Young JH, Rice K, Duan Q, Chen F, Li Y, Tang H, Fornage M, Keene KL, Andrews JS, Smith JA, Faul JD, Guangfa Z,. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet. 2013;93(3):545-554.

Mongraw-Chaffin ML, Golden SH, Allison MA, Ouyang P, Woodward M, Young JH, Schreiner PJ, Szkio M, Ding JZ, Anderson CA. The sex and race specific relationship between anthropometry and body composition by computed tomography: the Multi-Ethnic Study of Atherosclerosis [abstract]. Circulation. 2013;127(12 Suppl):AP302.

Mitchell GF, Verwoert GC, Tarasov KV, Isaacs A, Smith AV, Liu Y, Andrews JS, Howard TD, Herrington DM, Ding J, et al. Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circ Cardiovasc Genet. 2012;5(1):81-90.

Murabito JM, White CC, Kavousi M, Sun YV, Feitosa MF, Nambi V, Lamina C, Schillert A, Coassin S, Bis JC, Broer L, Crawford DC, Franceschini N, Frikke-Schmidt R, Haun M, Holewijn S, Huffman JE, Hwang S-J, Kiechl S, Kollerits B, Montasser ME,. Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet. 2012;5(1):100-112.

Pattaro C, Kottgen A, Teumer A, Garnaas M, Boger CA, Fuchsberger C, Olden M, Chen M-H, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, Lohman K, Ding J, Andrews JS, Freedman BI, Liu Y, et al. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet. 2012;8(3):e1002584.

Ding J, Lovato J, Hugenschmidt CE, Ambrosius W, Horowitz K, Bryan RN, Greven C, Gerstein HC, Lazer R, Murray A, Thomas A, Launer L, Williamson J. Retinopathy in relation to cerebral ischemic lesion and cognitive decline in older patients with type 2 diabetes [abstract]. Diabetes. 2012;61(Suppl 1A):LB2.

Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, Arking DE, Muller-Nurasyid M, Krijthe BP, Lubitz SA, Bis JC, Chung MK, Dorr M, Ozaki K, Roberts JD, Smith JG, Pfeufer A, Sinner MF, Lohman K, Ding J, Smith NL, Smith JD. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet. 2012;44(6):670-675.

Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K, Johnson AD, Foster MC, Greenawalt DM, Griffin P, Ding J, Newman AB, Tylavsky F, Miljkovic I, Kritchevsky SB, Launer L, Garcia M, Eiriksdottir G, Carr JJ,. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet. 2012;8(5):e1002695.

Jenny NS, French B, Arnold AM, Strotmeyer ES, Cushman M, Chaves PHM, Ding J, Fried LP, Kritchevsky SB, Rifkin DE, Sarnak MJ, Newman AB. Long-term assessment of inflammation and healthy aging in late life: the Cardiovascular Health Study All Stars. J Gerontol A Biol Sci Med Sci. 2012;67(9):970-976.

Rosano C, Aizenstein HJ, Newman AB, Venkatraman V, Harris T, Ding J, Satterfield S, Yaffe K. Neuroimaging differences between older adults with maintained versus declining cognition over a 10-year period. Neuroimage. 2012;62(1):307-313.

Yeboah J, Carr JJ, Terry JG, Ding J, Zeb I, Liu S, Nasir K, Post W, Blumenthal RS, Budoff M. Computed tomography derived cardiovascular risk markers, incident cardiovascular events and all-cause mortality in adults free of clinical cardiovascular disease. The Multi-Ethnic Study of Atherosclerosis [abstract]. Circulation. 2012;126(21 Suppl):A9536.

Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, Okada Y, Polasek O, Westra HJ, Wang YA, Del Greco M F,. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet. 2012;91(4):744-753.

Rasmussen-Torvik LJ, Wassel CL, Ding J, Carr J, Cushman M, Jenny N, Allison MA. Associations of body mass index and insulin resistance with leptin, adiponectin, and the leptin-to-adiponectin ratio across ethnic groups: the Multi-Ethnic Study of Atherosclerosis (MESA). Ann Epidemiol. 2012;22(10):705-709.

Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Boger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR,. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet. 2012;21(24):5329-5343.

Qi Q, Menzaghi C, Smith S, Liang L, de Rekeneire N, Garcia ME, Lohman KK, Miljkovic I, Strotmeyer ES, Cummings SR, Kanaya AM, Tylavsky FA, Satterfield S, Ding J, Rimm EB, Trischitta V, Hu FB, Liu Y, Qi L. Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels. Hum Mol Genet. 2012;21(21):4774-4780.

Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL, Williams SM, Ikram MA, Kleber ME, Becker DM, Truong V, Mychaleckyj JC, Tang W, Yang Q,. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 2012;120(24):4873-4881.

Brinkley TE, Kitzman DW, Ding J, Nicklas BJ, Kritchevsky SB, Hundley WG. Epicardial, pericardial and periaortic fat are elevated in older adults at high cardiac risk [abstract]. Arterioscler Thromb Vasc Biol. 2012;32(5 Suppl):A132.

Babcock MJ, Soliman EZ, Ding J, Kronmal RA, Goff DC Jr. Pericardial fat and atrial conduction abnormalities in the Multiethnic Study of Atherosclerosis (MESA). Obesity (Silver Spring). 2011;19(1):179-184.

Yaffe K, Weston A, Graff-Radford NR, Satterfield S, Simonsick EM, Younkin SG, Younkin LH, Kuller L, Ayonayon HN, Ding J, et al. Association of plasma beta-amyloid level and cognitive reserve with subsequent cognitive decline. JAMA. 2011;305(3):261-266.

Liu J, Fox CS, Hickson DA, May WL, Ding J, Carr JJ, Taylor HA. Pericardial fat and echocardiographic measures of cardiac abnormalities: the Jackson Heart Study. Diabetes Care. 2011;34(2):341-346.

Brinkley TE, Hsu F-C, Carr JJ, Hundley WG, Bluemke DA, Polak JF, Ding J. Pericardial fat is associated with carotid stiffness in the Multi-Ethnic Study of Atherosclerosis. Nutr Metab Cardiovasc Dis. 2011;21(5):332-338.

Brinkley TE, Ding J, Carr JJ, Nicklas BJ. Pericardial fat loss in postmenopausal women under conditions of equal energy deficit. Med Sci Sports Exerc. 2011;43(5):808-814.

Houston DK, Ding J, Lee JS, Garcia M, Kanaya AM, Tylavsky FA, Newman AB, Visser M, Kritchevsky SB. Dietary fat and cholesterol and risk of cardiovascular disease in older adults: the Health ABC Study. Nutr Metab Cardiovasc Dis. 2011;21(6):430-437.

Chughtai H, Morgan TM, Hamilton CA, Charoenpanichkit C, Ding J, Brinkley TE, Hundley WG. Intraperitoneal fat is associated with thickening of the thoracic aorta in individuals at high risk for cardiovascular events [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl 1):E1597.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Gerontology and Geriatric Medicine

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