Profile

Thomas D. DuBose Jr, M.D.

Thomas D. DuBose Jr, M.D.

Professor, Nephrology
Translational Science Institute
Maya Angelou Center for Health Equity
WFU Primate Center
Translational Science Institute
Physiology & Pharmacology
Institute for Regenerative Medicine

Clinical Specialties

Tubular Disorders, Hypertension (difficult), Kidney Disease (Chronic), Acid-based Electrolyte Disorders

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-4650
Department: 336-716-4650

Media Medical Expert »

Insurance Accepted »

Education & Training

  • M.D., University of Alabama School of Medicine , 1970
  • B.S., University of Alabama-Birmingham , 1966
  • Internship, Medicine, U Alabama Affil Hospitals, 1971
  • Residency, Internal Medicine, Parkland Memorial Hosp, 1973
  • Fellowship, Nephrology, University of Texas Health Sci Center-Dallas, 1977

Board Certifications

  • American Board of Internal Medicine

Memberships

  • Int'L Society Of Nephrology
  • Nat'L Kidney Foundation
  • New York Academy Of Sciences
  • Soc Of Sigma Xi
  • Southern Society Of Clinical I
  • Am Clinical & Climatological A
  • Am Coll Of Physicians
  • Am Federation Of Clinical Rese
  • Am Heart Association
  • Am Physiological Society
  • Am Soc Of Clinical Investigati
  • Am Soc Of Hypertension
  • Am Soc Of Nephrology
  • Am Soc.Of Transplant Physician
  • Assn Of American Physicians
  • Assn Of Professors Of Medicine

NPI Number

  • 1164405874
Thomas D. DuBose Jr, M.D.

Thomas D. DuBose Jr, M.D.

Professor, Nephrology Translational Science Institute
Maya Angelou Center for Health Equity
WFU Primate Center
Translational Science Institute
Physiology & Pharmacology
Institute for Regenerative Medicine

Research Interests

drugs/therapeutic agents pharm, hormones/cytokines/signalling, molecular biology/molecular me, structural biology

Contact Information

Academic: 336-716-2715 | Department: 336-716-4650

Media Medical Expert »

Recent Publications

Dubose TD Jr, Santos RM. Vascular disorders of the kidney In: Goldman L, Schafer AI, eds. Goldman's Cecil medicine, vol 1. 24th ed. Philadelphia: Elsevier/Saunders;2012: 783-788.

DuBose TD Jr. Disorders of acid-base balance In: Taal MW, Chertow GM, Marsden PA, Skorecki K, Yu ASL, Brenner BM, eds. Brenner & Rector's the kidney, vol 1. 9th ed. Philadelphia: Elsevier Saunders;2012: 595-639.

DuBose TD Jr. Acidosis and alkalosis In: Longo DL, Kasper DL, Jameson JL, Fauci AS, Hauser SL, Loscalzo J, eds. Harrison's principles of internal medicine, vol 1. 18th ed. New York: McGraw-Hill;2012: 363-373.

Saxena H, Deshpande DA, Tiegs BC, Yan H, Battafarano RJ, Burrows WM, Damera G, Panettieri RA, Dubose TD Jr, An SS, Penn RB. The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH. Br J Pharmacol. 2012;166(3):981-990.

Horvat SJ, Deshpande DA, Yan H, Panettieri RA, Codina J, Dubose TD Jr, Xin W, Rich TC, Penn RB. A-kinase anchoring proteins regulate compartmentalized cAMP signaling in airway smooth muscle. FASEB J. 2012;26(9):3670-3679.

Fisher KD, Codina J, Petrovic S, DuBose TD Jr. Pyk2 regulates H+-ATPase-mediated proton secretion in the outer medullary collecting duct via an ERK1/2 signaling pathway. Am J Physiol Renal Physiol. 2012;303(9):F1353-1362.

Ruiz J, Wallace EL, Miller DP, Loeser RF, Miles M, DuBose TD, Lichstein PR. A comprehensive 3-year internal medicine residency research curriculum. Am J Med. 2011;124(5):469-473.

Codina J, Opyd TS, Powell ZB, Furdui CM, Petrovic S, Penn RB, DuBose TD Jr. pH-dependent regulation of the alpha-subunit of H+-K+-ATPase (HKalpha2). Am J Physiol Renal Physiol. 2011;301(3):F536-F543.

Drafts BC, Sutton BJ, Dubose TD Jr, Thohan V. Incessant ventricular tachycardia and cardiogenic shock: a common presentation of an uncommon diagnosis. Am J Med Sci. 2011;342(6):527-529.

DuBose TD Jr, Daeihagh, P. Metabolic acidosis and alkalosis In: Vincent JL, ed. Textbook of critical care. 6th ed. Philadelphia: Elsevier/Saunders;2011: 823-840.

Moossavi S, Wallace EL, Martin TJ, Dubose TD. Hepatitis C virus and cocaine-induced rhabdomyolysis [editorial]. Am J Med. 2010;123(12):e5-e6.

Codina J, Petrovic S, Penn RB, DuBose TD. Induced but constrained expression of GPR4 mediates acid-induced HKalpha2 expression [abstract]. J Am Soc Nephrol. 2010;21(Suppl):255A.

Sun X, Stephens LM, Penn RB, DuBose TD, Petrovic S. Impaired cellular response to acid challenge in proton sensor null mice [abstract]. J Am Soc Nephrol. 2010;21(Suppl):254A.

DuBose TD Jr. Metabolic alkalosis In: Greenberg A, Cheung AK, Coffman TM, Falk RJ, Jennette JC, eds. Primer on kidney diseases. 5th ed. Philadelphia: Saunders Elsevier;2009: 84-90.

DuBose TD Jr, Behrens MT, Berns A, Davis C, Goldfarb S, Hostetter T, Klotman P, Linas S, Owens S, Szczech L, et al. The patient-centered medical home and nephrology [editorial]. J Am Soc Nephrol. 2009;20(4):681-682.

DuBose TD Jr. A 42-year-old woman with flaccid paralysis. Am J Kidney Dis. 2009;54(5):965-969.

DuBose TD Jr, Santos RM. Vascular disorders of the kidney In: Goldman L, Ausiello D, eds. Cecil medicine. 23rd ed. Philadelphia: Saunders Elsevier;2008: 891-897.

DuBose TD Jr. Acidosis and alkalosis In: Fauci AS, Kasper DL, Longo DL, Braunwald E, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison's principles of internal medicine, vol 1. 17th ed. New York: McGraw Hill Medical;2008: 287-296.

DuBose TD Jr. Disorders of acid-base balance In: Brenner BM, Rector FC, eds. Brenner & Rector's the kidney, vol 1. 8th ed. Philadelphia: Saunders Elsevier;2008: 505-546.


DuBose TD Jr. Metabolic and respiratory acidosis In: Wilcox CS, ed. Therapy in nephrology & hypertension: a companion to Brenner & Rector's The kidney. 3rd ed. Philadelphia: Saunders Elsevier;2008: 368-380.

Saran AM, DuBose TD Jr. Cardiovascular disease in chronic kidney disease. Ther Adv Cardiovasc Dis. 2008;2(6):425-434.

Levey AS, Andreoli SP, DuBose T, Provenzano R, Collins AJ. Chronic kidney disease: common, harmful, and treatable--World Kidney Day 2007. J Am Soc Nephrol. 2007;18(2):374-378.

Levey AS, Andreoli SP, DuBose T, Provenzano R, Collins AJ. Chronic kidney disease: common, harmful, and treatable--World Kidney Day 2007. Am J Nephrol. 2007;27(1):108-112.


Levey AS, Andreoli SP, DuBose T, Provenzano R, Collins AJ. Chronic kidney disease: common, harmful and treatable--World Kidney Day 2007 [editorial]. Pediatr Nephrol. 2007;22(3):321-325.

Himmelfarb J, Henrich W, DuBose T. Anemia of kidney disease and clinical practice guidelines: quo vadis?. Clin J Am Soc Nephrol. 2007;2(2):213-214.

Levey AS, Andreoli SP, DuBose T, Provenzano R, Collins AJ. Chronic kidney disease: common, harmful, and treatable--World Kidney Day 2007. Clin J Am Soc Nephrol. 2007;2(2):401-405.

Freedman BI, DuBose TD Jr. Chronic kidney disease: cause and consequence of cardiovascular disease [editorial]. Arch Intern Med. 2007;167(11):1113-1115.

Levey AS, Andreoli SP, DuBose T, Provenzano R, Collins AJ. CKD: common, harmful, and treatable -- World Kidney Day 2007 [editorial]. Am J Kidney Dis. 2007;49(2):175-179.

Codina J, Du W, DuBose TD. ATP1AL1 expression in human kidney [abstract]. J Am Soc Nephrol. 2007;18(Abstracts Issue):588A.

Codina J, Liu J, Bleyer AJ, Penn RB, DuBose TD Jr. Phosphorylation of S955 at the protein kinase A consensus promotes maturation of the alpha subunit of the colonic H+,K+-ATPase. J Am Soc Nephrol. 2006;17(7):1833-1840.

Codina J, DuBose TD Jr. Molecular regulation and physiology of the H+,K+-ATPases in kidney. Semin Nephrol. 2006;26(5):345-351.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Nephrology

Clinical Specialties

Tubular Disorders, Hypertension (difficult), Kidney Disease (Chronic), Acid-based Electrolyte Disorders

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