Profile

Jorge P. Figueroa, M.D.Wake Forest School of Medicine

Jorge P. Figueroa, M.D.

Professor,

Contact Information

Academic: 336-716-2351 | Department: 336-716-4039

Email: figueroa@wakehealth.edu

Education & Training

  • M.D., Univ of Chile School of Medicine Santiago-Chile, 1979
  • Ph.D., Cornell University, 1987
  • Fellowship, Univ of Chile School of Medici, 1982
Jorge P. Figueroa, M.D.

Jorge P. Figueroa, M.D.

Professor, Maternal-Fetal Medicine
Obstetrics & Gynecology

Research Interests

Betamethasone; Sheep; Glucocorticoids; Prenatal Exposure Delayed Effects; Fetal Hypoxia
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Contact Information

Academic: 336-716-2351 | Department: 336-716-4039

Email: figueroa@wakehealth.edu

Recent Publications

Antenatal exposure to betamethasone alters microRNA expression in white adipose tissue in adult sheep [abstract]. Figueroa JP, Massmann AG, Zhang J, Cox LA.. Reprod Sci. 2016;23(Suppl 1):232A.

Sex-dependent effects of antenatal exposure to betamethasone on omental fat in adult sheep [abstract]. Massmann AG, Zhang J, Seong WJ, Kim M, Figueroa JP.. Reprod Sci. 2016;23(Suppl 1):147A.

Antenatal glucocorticoid exposure affects adipose tissue in a sex and body weight dependent manner [abstract]. Zhang J, Massmann AG, Figueroa JP.. Reprod Sci. 2016;23(Suppl 1):232A-233A.

Arterial stiffening index (ASI) and blood pressure in lean and obese adult sheep exposed antenatally to glucocorticoids [abstract]. Figueroa JP, Massmann GA, Zhang J.. Reprod Sci. 2015;22(Suppl 1):165A.

Sex differences on the effects of antenatally to glucocorticoids on insulin resistance in lean and obese adult sheep [abstract]. Massmann GA, Zhang J, Figueroa JP.. Reprod Sci. 2015;22(Suppl 1):98A.

Antenatal glucocorticoid treatment alters sodium uptake in renal proximal tubule cells from adult offspring in a sex specific manner. Su Y, Bi J, Pulgar VM, Figueroa JP, Chappell MC, Rose JC.. Am J Physiol Renal Physiol. 2015;308(11):F1268-1275.

Sex differences in effects of nitric oxide donor (SNAP) on sodium uptake in ovine renal proximal tubule cells (RPTC) from prenatal betamethesone (beta) exposed young adult sheep [abstract]. Su YX, Tang LJ, Figueroa JP, Rose JC.. Reprod Sci. 2015;22(Suppl 1):357A.

Visceral fat is an important mediator of the cardiometabolic effects of antenatal glucocorticoids in adult sheep [abstract]. Zhang J, Massmann GA, Figueroa JP.. Reprod Sci. 2015;22(Suppl 1):358A.

Intracerebroventricular infusion of angiotensin-(1-7) improves baroreflex sensitivity in antenatal betamethasone exposed sheep [abstract]. Lawson MJ, Figueroa JP, Rose JC, Chappell MC, Diz DI, Shaltout HA.. FASEB J. 2015;29(1 Suppl):811.30.

Obesity induces further autonomic impairment in sheep exposed antenatally to betamethasone [abstract]. Lawson MJ, Shaltout HA, Chappell MC, Diz DI, Figueroa JP.. FASEB J. 2015;29(1 Suppl):LB724.

Effect of antenatal betamethasone on ovine renal function in obese offspring [abstract]. Bi JL, Figueroa J, Chappell M, Rose J.. FASEB J. 2015;29(Suppl 1):LB762.

Intracerebroventricular (ICV) infusion of angiotensin-(1-7) lowers blood pressure and improves autonomic function in antenatal betamethasone exposed sheep [abstract]. Lawson MJ, Figueroa JP, Chappell MC, Diz DI, Shaltout HA.. Hypertension. 2015;66(Suppl 1):A081.

Antenatal betamethasone increases vascular reactivity to endothelin-1 by upregulation of CD38/cADPR signaling. Lee JH, Zhang J, Massmann GA, Figueroa JP.. J Dev Orig Health Dis. 2014;5(1):56-62.

Role of transient receptor potential channels (TRPC) on vascular reactivity responses to endothelin in sheep exposed antenatally to betamethasone [abstract]. Figueroa JP, Zhang J, Massmann AG.. Reprod Sci. 2014;21(3 Suppl):164A.

Antenatal steroid exposure alters transient receptor potential cation channels (TRPC) function in adult sheep arteries [abstract]. Lee JH, Zhang J, Massman GA, Figueroa JP.. Reprod Sci. 2014;21(3 Suppl):163A-164A.

Sex differences in the effects of prenatal betamethesone (Beta) exposure on sodium uptake in ovine renal proximal tubule cells (RPTC) from young adult sheep [abstract]. Su YX, Jorge FP, Rose JC.. Reprod Sci. 2014;21(3 Suppl):367A.

Antenatal exposure to betamethasone has permanent effects on omental fat preadipocytes and on in vitro adipogenesis in adult sheep [abstract]. Zhang J, Massmann AG, Figueroa JP.. Reprod Sci. 2014;21(3 Suppl):165A.

Sex-specific effect of antenatal betamethasone exposure on renal oxidative stress induced by angiotensins in adult sheep. Bi J, Contag SA, Chen K, Su Y, Figueroa JP, Chappell MC, Rose JC.. Am J Physiol Renal Physiol. 2014;307(9):F1013-1022.

Antenatal betamethasone has a sex-dependent effect on the in vivo response to endothelin in adult sheep. Lee JH, Zhang J, Flores L, Rose JC, Massmann GA, Figueroa JP.. Am J Physiol Regul Integr Comp Physiol. 2013;304(8):R581-R587.

Gender affects responses of renal ACE and ACE2 activity to unilateral nephrectomy [abstract]. Chen K, Bi J, Su Y, Figueroa J, Chappell M, Rose J.. Reprod Sci. 2013;20(3 Suppl 1A):335A.

Gender differences in effects of prenatal betamethasone exposure on sheep renal ACE and ACE2 activity: a possible mechanism in fetal programmed hypertension in males [abstract]. Chen K, Bi J, Figueroa J, Chappell M, Rose J.. Reprod Sci. 2013;20(3 Suppl 1A):275A.

Antenatal betamethasone increases transient receptor potential cation channels (TRPC) expression in sheep arteries [abstract]. Zhang J, Lee J-H, Massmann AG, Figueroa JP.. Reprod Sci. 2013;20(3 Suppl):83A-84A.

Gender differences in the effect of antenatal betamethasone (Beta) exposure on NHE3 and Na/K-ATPase expression in adult sheep kidney [abstract]. Su Y, Bi J, Figueroa JP, Rose JC.. Reprod Sci. 2013;20(3 Suppl):141A-142A.

Antenatal betamethsone (Beta) effects on ryanodine (RyR) mediated vascular reactivity in adult sheep [abstract]. Lee J-H, Zhang J, Massmann AG, Flores L, Figueroa JP.. Reprod Sci. 2013;20(3 Suppl):202A-203A.

Antenatal glucocorticoids increase in vitro vascular reactivity in the adult offspring via the ADPR cyclase pathway [abstract]. Lee J-H, Zhang J, Massmann AG, Figueroa JP.. Reprod Sci. 2013;20(3 Suppl):203A.

Effects of antenatal glucocorticoids and diet-induced obesity on plasma and adipose tissue adiponectin [abstract]. Massmann AG, Flores L, Lee J-H, Zhang J, Figueroa JP.. Reprod Sci. 2013;20(3 Suppl):203A.

Effects of pre-pregnancy maternal obesityon adiponectin plasma concentration and adipose tissue expression [abstract]. Flores L, Massmann AG, Figueroa JP.. Reprod Sci. 2013;20(3 Suppl):245A.

Effects of severe obesity on the levels of inflammatory markers in maternal and fetal compartments at term [abstract]. Akoma UN, Guillermo VJ, Searing KL, Massmann AG, Figueroa JP.. Reprod Sci. 2013;20(3 Suppl):305A.

Sex differences in oxidative stress following uniphrectomy in antenatal glucocorticoid exposed sheep [abstract]. Bi JL, Contag S, Su YX, Chen K, Figueroa J, Chappell M, Rose JC.. FASEB J. 2013;27():733.2.

Gender differences in the effect of antenatal betamethasone (Beta) exposure on sodium uptake in ovine renal proximal tubule cells (RPTC) [abstract]. Su Y, Tang L, Bi J, Figueroa JP, Rose JC.. Reprod Sci. 2012;19(3 Suppl):345A.

Effects of prenatal betamethasone (Beta) exposure and unilateral nephrectomy on sodium uptake in ovine renal proximal tubule cells from young adult male sheep [abstract]. Su Y, Bi J, Tang L, Figueroa JP, Rose JC.. FASEB J. 2012;26(Meeting Abstracts):1102.3.

Impact of antenatal betamethasone (B) on p47 phox in kidney and 8-isoprostane responses to angiotensin II in proximal tubule cells in male sheep after uninephrectomy [abstract]. Bi J, Su Y, Figueroa J, Chappell MC, Rose JC.. FASEB J. 2012;26(Meeting Abstracts):1101.10.

Effects of antenatal glucocorticoids and diet-induced obesity on skeletal muscle insulin signaling pathways [abstract]. Massmann AG, Lee J-H, Flores L, Zhang J, Figueroa JP.. Reprod Sci. 2012;19(3 Suppl):264A.

Effects of antenatal glucocorticoids and diet-induced obesity on adipose tissue renin angiotensin system (RAS) in adult sheep [abstract]. Zhang J, Massmann AG, Figueroa JP.. Reprod Sci. 2012;19(3 Suppl):347A.

Antenatal betamethasone effects on visceral fat function are associated with cardiometabolic programming in adult sheep [abstract]. Figueroa JP, Zhang J, Massman AG [sic] [Massmann AG].. Reprod Sci. 2012;19(3 Suppl):158A.

The effect of antenatal steroid exposure on sodium uptake in ovine renal proximal tubule cells (RPTC) [abstract]. Tang L, Bi J, Chappell M, Figueroa J, Rose JC.. FASEB J. 2011;25(Meeting Abstracts):1029.12.

Antenatal betamethasone (B) and gender affect 8-isoprostane responses to unilateral nephrectomy [abstract]. Bi J, Tang L, Figueroa J, Chappell MC, Rose JC.. FASEB J. 2011;25(Meeting Abstracts):1029.11.

Effect of prenatal betamethasone exposure on renal functional reserve in the young adult female sheep [abstract]. Bi J, Figueroa JP, Chappell MC, Rose JC.. Reprod Sci. 2011;18(4 Suppl):90A.

Antenatal glucocorticoid exposure alters in vivo endothelin responsiveness and signaling in adult sheep [abstract]. Figueroa JP, Zhang J, Rose JC, Massmann AG.. Reprod Sci. 2011;18(4 Suppl):209A.

Pre-pregnancy maternal obesity increases blood pressure and vascular reactivity response to angiotensin II [abstract]. Massmann AG, Zhang J, Figueroa JP.. Reprod Sci. 2011;18(4 Suppl):215A.

Effect of early glucocorticoid treatment on GR and MR expression in adult sheep kidney [abstract]. Su Y, Shaltout HA, Figueroa JP, Chappell M, Rose JC.. Reprod Sci. 2011;18(4 Suppl):220A.

Antenatal glucocorticoids and diet-induced obesity alter adipose tissue function [abstract]. Zhang J, Massmann AG, Chappell MC, Figueroa JP.. Reprod Sci. 2011;18(4 Suppl):223A.

Gender-specific cardiovascular effects of prepregnancy maternal obesity in sheep [abstract]. Figueroa JP, Zhang J, Massmann AG.. J Dev Orig Health Dis. 2011;2(Suppl 1):S91.

Gender-specific effects of prenatal betamethesone (Beta) exposure and unilateral nephrectomy on the intrarenal renin-angiotension system (RAS) in adult sheep [abstract]. Su Y, Bi J, Figueroa JP, Rose JC.. Endocr Rev. 2011;32(3 Meeting Abstracts):.

Differential effects of clinical doses of antenatal betamethasone on nephron endowment and glomerular filtration rate in adult sheep. Zhang J, Massmann GA, Rose JC, Figueroa JP.. Reprod Sci. 2010;17(2):186-195.

Fetal and postnatal renin secretion in female sheep exposed to prenatal betamethasone. Connors N, Valego NK, Carey LC, Figueroa JP, Rose JC.. Reprod Sci. 2010;17(3):239-246.

A sheep model of maternal obesity: effects on plasma levels of inflammatory mediators in the offspring [abstract]. Massmann AG, Zhang J, Pulgar VM, Figueroa JP.. Reprod Sci. 2010;17(3 Suppl):192A.

Antenatal glucocorticoids and diet-induced obesity alter adipose tissue renin angiotensinin system (RAS) components in the adult offspring [abstract]. Massmann AG, Zhang J, Figueroa JP.. Reprod Sci. 2010;17(3 Suppl):222A.

Pre-pregnancy maternal obesity: a sheep model to study the impact of obesity on maternal adaptations [abstract]. Zhang J, Massmann A, Pulgar VM, Figueroa JP.. Reprod Sci. 2010;17(3 Suppl):211A.

Antenatal betamethasone alters vascular reactivity in adult female ovine cerebral arteries. Eckman DM, Kerr BA, Fuloria M, Simandle SA, Watt SE, Rose JC, Figueroa JP.. Pediatr Res. 2010;68(4):344-348.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Jorge P. Figueroa, M.D.

Jorge P. Figueroa, M.D.

Professor, Maternal-Fetal Medicine
Obstetrics & Gynecology

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