Profile

Jorge P. Figueroa, M.D.Wake Forest School of Medicine

Jorge P. Figueroa, M.D.

Professor,

Contact Information

Academic: 336-716-2351 | Department: 336-716-4039

Email: figueroa@wakehealth.edu

Education & Training

  • M.D., Univ of Chile School of Medicine Santiago-Chile, 1979
  • Ph.D., Cornell University, 1987
  • Fellowship, Univ of Chile School of Medici, 1982
Jorge P. Figueroa, M.D.

Jorge P. Figueroa, M.D.

Professor, Maternal-Fetal Medicine
Obstetrics & Gynecology

Research Interests

cell growth, differentiation,d, growth & development, hormones/cytokines/signalling, hypertension, maternal & child health, molecular biology/molecular me, obesity

Contact Information

Academic: 336-716-2351 | Department: 336-716-4039

Email: figueroa@wakehealth.edu

Recent Publications

Figueroa JP, Massmann AG, Zhang J, Cox LA. Antenatal exposure to betamethasone alters microRNA expression in white adipose tissue in adult sheep [abstract]. Reprod Sci. 2016;23(Suppl 1):232A.

Massmann AG, Zhang J, Seong WJ, Kim M, Figueroa JP. Sex-dependent effects of antenatal exposure to betamethasone on omental fat in adult sheep [abstract]. Reprod Sci. 2016;23(Suppl 1):147A.

Zhang J, Massmann AG, Figueroa JP. Antenatal glucocorticoid exposure affects adipose tissue in a sex and body weight dependent manner [abstract]. Reprod Sci. 2016;23(Suppl 1):232A-233A.

Figueroa JP, Massmann GA, Zhang J. Arterial stiffening index (ASI) and blood pressure in lean and obese adult sheep exposed antenatally to glucocorticoids [abstract]. Reprod Sci. 2015;22(Suppl 1):165A.

Massmann GA, Zhang J, Figueroa JP. Sex differences on the effects of antenatally to glucocorticoids on insulin resistance in lean and obese adult sheep [abstract]. Reprod Sci. 2015;22(Suppl 1):98A.

Su Y, Bi J, Pulgar VM, Figueroa JP, Chappell MC, Rose JC. Antenatal glucocorticoid treatment alters sodium uptake in renal proximal tubule cells from adult offspring in a sex specific manner. Am J Physiol Renal Physiol. 2015;308(11):F1268-1275.

Su YX, Tang LJ, Figueroa JP, Rose JC. Sex differences in effects of nitric oxide donor (SNAP) on sodium uptake in ovine renal proximal tubule cells (RPTC) from prenatal betamethesone (beta) exposed young adult sheep [abstract]. Reprod Sci. 2015;22(Suppl 1):357A.

Zhang J, Massmann GA, Figueroa JP. Visceral fat is an important mediator of the cardiometabolic effects of antenatal glucocorticoids in adult sheep [abstract]. Reprod Sci. 2015;22(Suppl 1):358A.

Lawson MJ, Figueroa JP, Rose JC, Chappell MC, Diz DI, Shaltout HA. Intracerebroventricular infusion of angiotensin-(1-7) improves baroreflex sensitivity in antenatal betamethasone exposed sheep [abstract]. FASEB J. 2015;29(1 Suppl):811.30.

Lawson MJ, Shaltout HA, Chappell MC, Diz DI, Figueroa JP. Obesity induces further autonomic impairment in sheep exposed antenatally to betamethasone [abstract]. FASEB J. 2015;29(1 Suppl):LB724.

Bi JL, Figueroa J, Chappell M, Rose J. Effect of antenatal betamethasone on ovine renal function in obese offspring [abstract]. FASEB J. 2015;29(Suppl 1):LB762.

Lawson MJ, Figueroa JP, Chappell MC, Diz DI, Shaltout HA. Intracerebroventricular (ICV) infusion of angiotensin-(1-7) lowers blood pressure and improves autonomic function in antenatal betamethasone exposed sheep [abstract]. Hypertension. 2015;66(Suppl 1):A081.

Lee JH, Zhang J, Massmann GA, Figueroa JP. Antenatal betamethasone increases vascular reactivity to endothelin-1 by upregulation of CD38/cADPR signaling. J Dev Orig Health Dis. 2014;5(1):56-62.

Figueroa JP, Zhang J, Massmann AG. Role of transient receptor potential channels (TRPC) on vascular reactivity responses to endothelin in sheep exposed antenatally to betamethasone [abstract]. Reprod Sci. 2014;21(3 Suppl):164A.

Lee JH, Zhang J, Massman GA, Figueroa JP. Antenatal steroid exposure alters transient receptor potential cation channels (TRPC) function in adult sheep arteries [abstract]. Reprod Sci. 2014;21(3 Suppl):163A-164A.

Su YX, Jorge FP, Rose JC. Sex differences in the effects of prenatal betamethesone (Beta) exposure on sodium uptake in ovine renal proximal tubule cells (RPTC) from young adult sheep [abstract]. Reprod Sci. 2014;21(3 Suppl):367A.

Zhang J, Massmann AG, Figueroa JP. Antenatal exposure to betamethasone has permanent effects on omental fat preadipocytes and on in vitro adipogenesis in adult sheep [abstract]. Reprod Sci. 2014;21(3 Suppl):165A.

Bi J, Contag SA, Chen K, Su Y, Figueroa JP, Chappell MC, Rose JC. Sex-specific effect of antenatal betamethasone exposure on renal oxidative stress induced by angiotensins in adult sheep. Am J Physiol Renal Physiol. 2014;307(9):F1013-1022.

Lee JH, Zhang J, Flores L, Rose JC, Massmann GA, Figueroa JP. Antenatal betamethasone has a sex-dependent effect on the in vivo response to endothelin in adult sheep. Am J Physiol Regul Integr Comp Physiol. 2013;304(8):R581-R587.

Chen K, Bi J, Su Y, Figueroa J, Chappell M, Rose J. Gender affects responses of renal ACE and ACE2 activity to unilateral nephrectomy [abstract]. Reprod Sci. 2013;20(3 Suppl 1A):335A.

Chen K, Bi J, Figueroa J, Chappell M, Rose J. Gender differences in effects of prenatal betamethasone exposure on sheep renal ACE and ACE2 activity: a possible mechanism in fetal programmed hypertension in males [abstract]. Reprod Sci. 2013;20(3 Suppl 1A):275A.

Zhang J, Lee J-H, Massmann AG, Figueroa JP. Antenatal betamethasone increases transient receptor potential cation channels (TRPC) expression in sheep arteries [abstract]. Reprod Sci. 2013;20(3 Suppl):83A-84A.

Su Y, Bi J, Figueroa JP, Rose JC. Gender differences in the effect of antenatal betamethasone (Beta) exposure on NHE3 and Na/K-ATPase expression in adult sheep kidney [abstract]. Reprod Sci. 2013;20(3 Suppl):141A-142A.

Lee J-H, Zhang J, Massmann AG, Flores L, Figueroa JP. Antenatal betamethsone (Beta) effects on ryanodine (RyR) mediated vascular reactivity in adult sheep [abstract]. Reprod Sci. 2013;20(3 Suppl):202A-203A.

Lee J-H, Zhang J, Massmann AG, Figueroa JP. Antenatal glucocorticoids increase in vitro vascular reactivity in the adult offspring via the ADPR cyclase pathway [abstract]. Reprod Sci. 2013;20(3 Suppl):203A.

Massmann AG, Flores L, Lee J-H, Zhang J, Figueroa JP. Effects of antenatal glucocorticoids and diet-induced obesity on plasma and adipose tissue adiponectin [abstract]. Reprod Sci. 2013;20(3 Suppl):203A.

Flores L, Massmann AG, Figueroa JP. Effects of pre-pregnancy maternal obesityon adiponectin plasma concentration and adipose tissue expression [abstract]. Reprod Sci. 2013;20(3 Suppl):245A.

Akoma UN, Guillermo VJ, Searing KL, Massmann AG, Figueroa JP. Effects of severe obesity on the levels of inflammatory markers in maternal and fetal compartments at term [abstract]. Reprod Sci. 2013;20(3 Suppl):305A.

Bi JL, Contag S, Su YX, Chen K, Figueroa J, Chappell M, Rose JC. Sex differences in oxidative stress following uniphrectomy in antenatal glucocorticoid exposed sheep [abstract]. FASEB J. 2013;27():733.2.

Su Y, Tang L, Bi J, Figueroa JP, Rose JC. Gender differences in the effect of antenatal betamethasone (Beta) exposure on sodium uptake in ovine renal proximal tubule cells (RPTC) [abstract]. Reprod Sci. 2012;19(3 Suppl):345A.

Su Y, Bi J, Tang L, Figueroa JP, Rose JC. Effects of prenatal betamethasone (Beta) exposure and unilateral nephrectomy on sodium uptake in ovine renal proximal tubule cells from young adult male sheep [abstract]. FASEB J. 2012;26(Meeting Abstracts):1102.3.

Bi J, Su Y, Figueroa J, Chappell MC, Rose JC. Impact of antenatal betamethasone (B) on p47 phox in kidney and 8-isoprostane responses to angiotensin II in proximal tubule cells in male sheep after uninephrectomy [abstract]. FASEB J. 2012;26(Meeting Abstracts):1101.10.

Massmann AG, Lee J-H, Flores L, Zhang J, Figueroa JP. Effects of antenatal glucocorticoids and diet-induced obesity on skeletal muscle insulin signaling pathways [abstract]. Reprod Sci. 2012;19(3 Suppl):264A.

Zhang J, Massmann AG, Figueroa JP. Effects of antenatal glucocorticoids and diet-induced obesity on adipose tissue renin angiotensin system (RAS) in adult sheep [abstract]. Reprod Sci. 2012;19(3 Suppl):347A.

Figueroa JP, Zhang J, Massman AG [sic] [Massmann AG]. Antenatal betamethasone effects on visceral fat function are associated with cardiometabolic programming in adult sheep [abstract]. Reprod Sci. 2012;19(3 Suppl):158A.

Tang L, Bi J, Chappell M, Figueroa J, Rose JC. The effect of antenatal steroid exposure on sodium uptake in ovine renal proximal tubule cells (RPTC) [abstract]. FASEB J. 2011;25(Meeting Abstracts):1029.12.

Bi J, Tang L, Figueroa J, Chappell MC, Rose JC. Antenatal betamethasone (B) and gender affect 8-isoprostane responses to unilateral nephrectomy [abstract]. FASEB J. 2011;25(Meeting Abstracts):1029.11.

Bi J, Figueroa JP, Chappell MC, Rose JC. Effect of prenatal betamethasone exposure on renal functional reserve in the young adult female sheep [abstract]. Reprod Sci. 2011;18(4 Suppl):90A.

Figueroa JP, Zhang J, Rose JC, Massmann AG. Antenatal glucocorticoid exposure alters in vivo endothelin responsiveness and signaling in adult sheep [abstract]. Reprod Sci. 2011;18(4 Suppl):209A.

Massmann AG, Zhang J, Figueroa JP. Pre-pregnancy maternal obesity increases blood pressure and vascular reactivity response to angiotensin II [abstract]. Reprod Sci. 2011;18(4 Suppl):215A.

Su Y, Shaltout HA, Figueroa JP, Chappell M, Rose JC. Effect of early glucocorticoid treatment on GR and MR expression in adult sheep kidney [abstract]. Reprod Sci. 2011;18(4 Suppl):220A.

Zhang J, Massmann AG, Chappell MC, Figueroa JP. Antenatal glucocorticoids and diet-induced obesity alter adipose tissue function [abstract]. Reprod Sci. 2011;18(4 Suppl):223A.

Figueroa JP, Zhang J, Massmann AG. Gender-specific cardiovascular effects of prepregnancy maternal obesity in sheep [abstract]. J Dev Orig Health Dis. 2011;2(Suppl 1):S91.

Su Y, Bi J, Figueroa JP, Rose JC. Gender-specific effects of prenatal betamethesone (Beta) exposure and unilateral nephrectomy on the intrarenal renin-angiotension system (RAS) in adult sheep [abstract]. Endocr Rev. 2011;32(3 Meeting Abstracts):.

Zhang J, Massmann GA, Rose JC, Figueroa JP. Differential effects of clinical doses of antenatal betamethasone on nephron endowment and glomerular filtration rate in adult sheep. Reprod Sci. 2010;17(2):186-195.

Connors N, Valego NK, Carey LC, Figueroa JP, Rose JC. Fetal and postnatal renin secretion in female sheep exposed to prenatal betamethasone. Reprod Sci. 2010;17(3):239-246.

Massmann AG, Zhang J, Pulgar VM, Figueroa JP. A sheep model of maternal obesity: effects on plasma levels of inflammatory mediators in the offspring [abstract]. Reprod Sci. 2010;17(3 Suppl):192A.

Massmann AG, Zhang J, Figueroa JP. Antenatal glucocorticoids and diet-induced obesity alter adipose tissue renin angiotensinin system (RAS) components in the adult offspring [abstract]. Reprod Sci. 2010;17(3 Suppl):222A.

Zhang J, Massmann A, Pulgar VM, Figueroa JP. Pre-pregnancy maternal obesity: a sheep model to study the impact of obesity on maternal adaptations [abstract]. Reprod Sci. 2010;17(3 Suppl):211A.

Eckman DM, Kerr BA, Fuloria M, Simandle SA, Watt SE, Rose JC, Figueroa JP. Antenatal betamethasone alters vascular reactivity in adult female ovine cerebral arteries. Pediatr Res. 2010;68(4):344-348.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Jorge P. Figueroa, M.D.

Jorge P. Figueroa, M.D.

Professor, Maternal-Fetal Medicine
Obstetrics & Gynecology

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