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Karen M. Haas, Ph.D.Wake Forest School of Medicine

Karen M. Haas, Ph.D.

Associate Professor,
Ctr for Vaccines at Extremes

Contact Information

Academic: 336-716-0966 | Department: 336-716-0966


Education & Training

  • B.A., St Mary's University of Minnesota, 1995
  • Ph.D., University of Missouri-Columbia, 2000
  • Fellowship, Immunology, Duke University School of Medi, 2006
Karen M. Haas, Ph.D.

Karen M. Haas, Ph.D.

Associate Professor, Microbiology & Immunology
Ctr for Vaccines at Extremes

Research Interests

B-Lymphocytes; B-Lymphocyte Subsets; Antibody Formation; Mice, Inbred C57BL; Receptors, Complement 3d
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Contact Information

Academic: 336-716-0966 | Department: 336-716-0966


Recent Publications

CD22 promotes B-1b cell responses to T cell-independent type 2 antigens. Haas KM, Johnson KL, Phipps JP, Do C.. J Immunol. 2018;200(5):1671-1681.

PD-L2 regulates B-1 cell antibody production against phosphorylcholine through an IL-5-dependent mechanism. McKay JT, Haro MA, Daly CA, Yammani RD, Pang B, Swords WE, Haas KM.. J Immunol. 2017;199(6):2020-2029.

Valency and density matter: deciphering impacts of immunogen structures on immune responses against a tumor associated carbohydrate antigen using synthetic glycopolymers. Qin Q, Yin Z, Wu X, Haas KM, Huang X.. Biomaterials. 2016;101():189-198.

PD-1 suppresses development of humoral responses that protect against Tn-bearing tumors. Haro MA, Littrell CA, Yin Z, Huang X, Haas KM.. Cancer Immunol Res. 2016;4(12):1027-1037.

NuMA controls 53BP1 dynamics and function in DNA double-strand break repair [abstract]. Liu J, Moreno NS, Parker L, Haas K, Lelievre SA, Vidi P.. Mol Biol Cell. 2016;27():P1236.

PD-1 suppresses protective immunity to Streptococcus pneumoniae through a B cell-intrinsic mechanism. McKay JT, Egan RP, Yammani RD, Chen L, Shin T, Yagita H, Haas KM.. J Immunol. 2015;194(5):2289-2299.

B-1 lymphocytes in mice and nonhuman primates. Haas KM.. Ann N Y Acad Sci. 2015;1362(1):98-109.

PD-1 suppresses antibody responses to Tn(+) tumors [abstract]. Leyva MA, Haas KM.. Cancer Res. 2015;75(15 Suppl):LB-217.

Aging promotes B-1b cell responses to native, but not protein-conjugated, pneumococcal polysaccharides: implications for vaccine protection in older adults. Haas KM, Blevins MW, High KP, Pang B, Swords WE, Yammani RD.. J Infect Dis. 2014;209(1):87-97.

C4 deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production. Yammani RD, Leyva MA, Jennings RN, Haas KM.. J Immunol. 2014;193(11):5434-5443.

Primate B-1 cells generate antigen-specific B cell responses to T cell-independent type 2 antigens. Yammani RD, Haas KM.. J Immunol. 2013;190(7):3100-3108.

The reversible formation of cysteine sulfenic acid promotes B-cell activation and proliferation. Crump KE, Juneau DG, Poole LB, Haas KM, Grayson JM.. Eur J Immunol. 2012;42(8):2152-2164.

A c-Myc and surface CD19 signaling amplification loop promotes B cell lymphoma development and progression in mice. Poe JC, Minard-Colin V, Kountikov EI, Haas KM, Tedder TF.. J Immunol. 2012;189(5):2318-2325.

PD-1:PD-1 ligand interactions suppress B-1b cell responses to T cell-independent type 2 antigens [abstract]. Haas K.. J Immunol. 2011;186(1 Meeting Abstracts):61.7.

The role of reactive oxygen intermediates in B cell activiation and differentiation [abstract]. Crump K, Liu C, Konopitski A, Poole L, Haas K, Grayson J.. J Immunol. 2011;186(1 Meeting Abstracts):45.12.

Programmed cell death 1 suppresses B-1b cell expansion and long-lived IgG production in response to T cell-independent type 2 antigens. Haas KM.. J Immunol. 2011;187(10):5183-5195.

Partial splenectomy but not total splenectomy preserves immunoglobulin M memory B cells in mice. Tracy ET, Haas KM, Gentry T, Danko M, Roberts JL, Kurtzberg J, Rice HE.. J Pediatr Surg. 2011;46(9):1706-1710.

Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice. Haas KM, Watanabe R, Matsushita T, Nakashima H, Ishiura N, Okochi H, Fujimoto M, Tedder TF.. J Immunol. 2010;184(9):4789-4800.

B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals. Smith SH, Haas KM, Poe JC, Yanaba K, Ward CD, Migone T-S, Tedder TF.. Int Immunol. 2010;22(8):681-691.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Microbiology & Immunology

Karen M. Haas, Ph.D.

Karen M. Haas, Ph.D.

Associate Professor, Microbiology & Immunology
Ctr for Vaccines at Extremes

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