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Craig A. Hamilton, Ph.D.Wake Forest School of Medicine

Craig A. Hamilton, Ph.D.

Associate Professor,



Contact Information

Academic: 336-716-2819 | Department: 336-716-2819

Email: crhamilt@wakehealth.edu

Education & Training

  • B.S.E.E., Georgia Institute of Technology , 1977
  • M.S.E.E., North Carolina State University , 1990
  • Ph.D., North Carolina State University , 1992

Memberships

  • Int'L Soc.Of Magnetic Resonanc
  • Inst Of Elec & Electron Engrs
Craig A. Hamilton, Ph.D.

Craig A. Hamilton, Ph.D.

Associate Professor, Biomedical Engineering
Sticht Center on Aging
Institute for Regenerative Medicine
Translational Science Institute

Contact Information

Academic: 336-716-2819 | Department: 336-716-2819

Email: crhamilt@wakehealth.edu

Recent Publications

Hall ME, Rocco MV, Morgan TM, Hamilton CA, Edwards MS, Jordan JH, Hurie JB, Hundley WG. Chronic diuretic therapy attenuates renal BOLD magnetic resonance response to an acute furosemide stimulus. J Cardiovasc Magn Reson. 2014;16(1):17.

Hundley WG, D'Agostino RB, Hamilton CA, inventors; Wake Forest University Health Sciences, assignee. Workstations with circutis for generating images of global injury. United States patent US 8,660,327. 2014 Feb 25. 2014;():.

Hundley WG, Lane KS, Morgan TM, Hamilton CA, Torti FM, inventors; Wake Forest University Health Sciences, assignee. Tissue evaluation using global characteristics of non-invasive imaging and systems for determining global tissue characteristics of images. Canada patent CA 2,555,373. 2014 Apr 29. 2014;():.

Andersen MM, Kritchevsky SB, Morgan TM, Hire DG, Vasu S, Brinkley TE, Kitzman DW, Hamilton CA, Soots S, Hundley WG. Increased cardiovascular stiffness and impaired age-related functional status. J Gerontol A Biol Sci Med Sci. 2014;():.

Miller CD, Case LD, Little WC, Mahler SA, Burke GL, Harper EN, Lefebvre C, Hiestand B, Hoekstra JW, Hamilton CA, Hundley WG. Stress CMR reduces revascularization, hospital readmission, and recurrent cardiac testing in intermediate-risk patients with acute chest pain. JACC Cardiovasc Imaging. 2013;6(7):785-794.

Drafts BC, Twomley KM, D'Agostino R Jr, Lawrence J, Avis N, Ellis LR, Thohan V, Jordan J, Melin SA, Torti FM, Little WC, Hamilton CA, Hundley WG. Low to moderate dose anthracycline-based chemotherapy is associated with early noninvasive imaging evidence of subclinical cardiovascular disease. JACC Cardiovasc Imaging. 2013;6(8):877-885.

Jordan JH, Morgan TM, Ellis LR, Lawrence J, Hall ME, Castellino SM, Hamilton CA, Torti FM, Vasu S, D'Agostino RB, Hundley WG. Pathologic atrophy of the left ventricular myocardium early after receipt of anthracycline-based chemotherapy [abstract]. Circulation. 2013;128(22 Suppl):A17537.

Hall ME, Brinkley TE, Morgan T, Hamilton CA, Jordan JH, Stacey RB, Chugtai H, Soots S, Little WC, Hundley WG. Ectopic fat is associated with gender-specific reductions in left ventricular myocardial perfusion index during dobutamine stress [abstract]. Circulation. 2013;128(22 Suppl):A17990.

Vasu S, Morgan TM, Kitzman DW, Hamilton CA, Chiles C, Soots S, Thohan V, Hundley WG. Abnormal stress induced changes in arterial stiffness in middle aged men and women with impaired fasting glucose at risk of their first episode of symptomatic heart failure [abstract]. Circulation. 2013;128(22 Suppl):A18679.

Hundley WG, Hamilton CA, inventors; Wake Forest University Health Sciences, assignee. Cardiac diagnostics using wall motion and perfusion cardiac MRI imaging and systems for cardiac diagnostics. European patent office patent EU 2,430,976. 2013 Dec 11; (patent also held in Spain, Netherlands, Italy, Germany, France, and Japan). 2013;():.

Hundley WG, Lane KS, Morgan TM, Hamilton CA, Torti FM, inventors; Wake Forest University Health Sciences, assignee. Non-invasive imaging for determination of global tissue characteristics. United States patent US 8,532,739. 2013 Sept 10. 2013;():.

Hundley WG, Hamilton CA, inventors; Wake Forest University Health Sciences, assignee. Cardiac diagnostics using time compensated stress test cardiac MRI imaging and systems for cardiac diagnostics. United States patent US 8,494,611. 2013 July 23. 2013;():.

Miller CD, Hoekstra JW, Lefebvre C, Blumstein H, Hamilton CA, Harper EN, Mahler S, Diercks DB, Neiberg R, Hundley WG. Provider-directed imaging stress testing reduces health care expenditures in lower-risk chest pain patients presenting to the emergency department. Circ Cardiovasc Imaging. 2012;5(1):111-118.

Jeevanantham V, Chughtai H, Little WC, Morgan T, Kitzman DW, Hamilton CA, Hundley WG. Aging reduces left atrial performance during adrenergic stress in middle aged and older patients. Cardiol J. 2012;19(1):45-52.

Chotenimitkhun R, D'Agostino RB Jr, Lawrence JA, Hamilton CA, Jordan J, Vasu S, Lash TL, Hundley W. Preservation of left ventricular ejection fraction with statins during receipt of anthracycline based chemotherapy [abstract]. J Am Coll Cardiol. 2012;59(13 Suppl):E986.

Hamilton CA, inventor; Wake Forest University Health Sciences, assignee. Cardiac visualization systems for displaying 3-D images of cardiac voxel intensity distributions with optional physician interactive boundary tracing tools. United States patent US 8,103,073 B2. 2012 Jan 24. 2012;():.

Hamilton CA, Hundley WG, inventors; Wake Forest University Health Sciences, assignee. Cardiac diagnostics using wall motion and perfusion cardiac MRI imaging & systems for cardiac diagnostics. United States patent US 8,290,567. 2012 Oct 16. 2012;():.

Charoenpanichkit C, Little WC, Mandapaka S, Dall'Armellina E, Morgan TM, Hamilton CA, Hundley WG. Impaired left ventricular stroke volume reserve during clinical dobutamine stress predicts future episodes of pulmonary edema. J Am Coll Cardiol. 2011;57(7):839-848.

Kumar R, Charonko J, Hundley WG, Hamilton CA, Stewart KC, McNeal GR, Vlachos PP, Little WC. Assessment of left ventricular diastolic function using 4-dimensional phase-contrast cardiac magnetic resonance. J Comput Assist Tomogr. 2011;35(1):108-112.

Jordan JH, D'Agostino RB Jr, Hamilton CA, Hundley WG. Early increase in myocardial cardiovascular magnetic resonance gadolinium signal intensity after anthracyclines but not other agents used to treat breast cancer or hematologic malignancy [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl 1):E782.

Miller C, Hwang W, Case D, Hoekstra JW, Lefebvre C, Blumstein H, Hamilton CA, Harper EN, Hundley WG. In emergency department patients with acute chest pain, stress cardiac MRI observation unit care reduces 1-year cardiac-related health care expenditures: a randomized trial [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl 1):E1187.

Chughtai H, Morgan TM, Hamilton CA, Charoenpanichkit C, Ding J, Brinkley TE, Hundley WG. Intraperitoneal fat is associated with thickening of the thoracic aorta in individuals at high risk for cardiovascular events [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl 1):E1597.

Miller CD, Hoekstra JW, Lefevbre C [sic] [Lefebvre C], Blumstein H, Hamilton CA, Harper EN, Mahler S, Diercks DB, Neiberg RH, Hundley WG. A randomized trial comparing stress cardiac MRI to conventional testing among observation unit patients with chest pain [abstract]. Acad Emerg Med. 2011;18(Suppl 1):S12.

Hamilton C, inventor; Wake Forest University Health Sciences, assignee. Cardiac visualization systems for displaying 3-D images of cardiac voxel intensity distributions with optional physician interactive boundary tracing tools. United States patent US 7,907,759. 2011 Mar 15. 2011;():.

Tan H, Hoge WS, Hamilton CA, Gunther M, Kraft RA. 3D GRASE PROPELLER: improved image acquisition technique for arterial spin labeling perfusion imaging. Magn Reson Med. 2011;66(1):168-173.

Miller CD, Hwang W, Case D, Hoekstra JW, Lefebvre C, Blumstein H, Hamilton CA, Harper EN, Hundley WG. Stress CMR imaging observation unit in the emergency department reduces 1-year medical care costs in patients with acute chest pain: a randomized study for comparison with inpatient care. JACC Cardiovasc Imaging. 2011;4(8):862-870.

Chughtai HL, Morgan TM, Hamilton CA, Charoenpanichkit C, Ding J, Brinkley TE, Hundley WG. Intraperitoneal fat is associated with thickening of the thoracic aorta in individuals at high risk for cardiovascular events. Obesity (Silver Spring). 2011;19(9):1784-1790.

Mandapaka S, Hamilton CA, Morgan TM, Hundley WG. Simultaneous measurement of left and right ventricular volumes and ejection fraction during dobutamine stress cardiovascular magnetic resonance. J Comput Assist Tomogr. 2011;35(5):614-617.

Chotenimitkhun R, Hamilton CA, Jeffries N, Harman JL, Taylor H Jr, Carr JJ, Hundley WG. Age related change in aortic stiffness in the thoracic and abdominal aorta among African Americans: the Jackson Heart Study [abstract]. Circulation. 2011;124(21 Suppl):A8579.

Hundley G, Hamilton CA, inventors; Wake Forest University Health Sciences, assignee. Cardiac diagnostics using wall motion and perfusion cardiac MRI imaging and systems for cardiac diagnostics cardiac MRI cine viewer 'scine': PAR I: Cardiac diagnostics using time compensated stress test cardiac MRI imaging. Eurpean patent office EP 1538981. 2011 Oct 26. 2011;():.

Puntawangkoon C, Morgan TM, Herrington DM, Hamilton CA, Hundley WG. Submaximal exercise coronary artery flow increases in postmenopausal women without coronary artery disease after estrogen and atorvastatin. Menopause. 2010;17(1):114-120.

Chaosuwannakit N, D'Agostino R Jr, Hamilton CA, Lane KS, Ntim WO, Lawrence J, Melin SA, Ellis LR, Torti FM, Little WC, Hundley WG. Aortic stiffness increases upon receipt of anthracycline chemotherapy. J Clin Oncol. 2010;28(1):166-172.

Drafts BC, Rerkpattanapipat P, Morgan TM, Hamilton CA, Ntim W, Hundley WG. Feasibility and early prognostic data on treadmill exercise magnetic resonance imaging stress testing [abstract]. J Am Coll Cardiol. 2010;55(10A):A84.E791.

Charoenpanichkit C, Morgan TM, Hamilton CA, Wallace EL, Robinson K, Ntim WO, Hundley WG. Prognostic importance of left ventricular hypertrophy in patients undergoing dobutamine stress testing [abstract]. J Cardiovasc Magn Reson. 2010;12(Suppl 1):07.

Chughtai H, Morgan TM, Hamilton CA, Charoenpanichkit C, Ding J, Brinkley TE, Hundley WG. Visceral fat is associated with an adverse increase in the thickness of the wall of the ascending thoracic aorta [abstract]. J Cardiovasc Magn Reson. 2010;12(Suppl 1):P126.

Hamilton C, Hundley G, Morgan T, Lane K, Torti F. Non-invasive systems and methods for the determination of cardiac injury using a characterizing portion of a Voxel histogram. United States patent US 7,747,308. 2010 June 29. 2010;():.

Charoenpanichkit C, Morgan TM, Hamilton CA, Wallace EL, Robinson K, Ntim WO, Hundley WG. Left ventricular hypertrophy influences cardiac prognosis in patients undergoing dobutamine cardiac stress testing. Circ Cardiovasc Imaging. 2010;3(4):392-397.

Lightfoot JC, D'Agostino RB Jr, Hamilton CA, Jordan J, Torti FM, Kock ND, Jordan J, Workman S, Hundley WG. Novel approach to early detection of doxorubicin cardiotoxicity by gadolinium-enhanced cardiovascular magnetic resonance imaging in an experimental model. Circ Cardiovasc Imaging. 2010;3(5):550-558.

Hamilton CA, Jordan JH, Kraft RA, Hundley WG. Noninterleaved velocity encodings for improved temporal and spatial resolution in phase-contrast magnetic resonance imaging. J Comput Assist Tomogr. 2010;34(4):570-574.

Chughtai HL, Morgan TM, Rocco M, Stacey B, Brinkley TE, Ding J, Nicklas B, Hamilton C, Hundley WG. Renal sinus fat and poor blood pressure control in middle-aged and elderly individuals at risk for cardiovascular events. Hypertension. 2010;56(5):901-906.

Miller CD, Hwang W, Hoekstra JW, Case D, Lefebvre C, Blumstein H, Hiestand B, Hamilton CA, Harper EN, Hundley WG, et al. Stress cardiac magnetic resonance imaging with observation unit care reduces cost for patients with emergent chest pain: a randomized trial. Ann Emerg Med. 2010;56(3):209-219.

Twomley K, D'Agostino R Jr, Lawrence J, Melin S, Ellis LR, Stacey B, Hamilton CA, Torti F, Little W, Hundley W. Early and persistent evidence of subclinical cardiovascular injury after receipt of anthracycline chemotherapy [abstract]. Circulation. 2010;122(21 Suppl):A12766.

Hundley WG, Hamilton C, inventors; Wake Forest University Health Sciences, assignee. Cardiac diagnostics using wall motion and perfusion cardiac MRI imaging and systems for cardiac diagnostics. United States patent US 7,818,043. 2010 Oct 19. 2010;():.

Wallace EL, Morgan TM, Walsh TF, Dall'Armellina E, Ntim W, Hamilton CA, Hundley WG. Dobutamine cardiac magnetic resonance results predict cardiac prognosis in women with known or suspected ischemic heart disease. JACC Cardiovasc Imaging. 2009;2(3):299-307.

Kemper KJ, Fletcher NB, Hamilton CA, McLean TW. Impact of healing touch on pediatric oncology outpatients: pilot study. J Soc Integr Oncol. 2009;7(1):12-18.

Tumkosit M, Puntawangkoon C, Morgan TM, Clark HP, Hamilton CA, Ntim WO, Clark PB, Hundley WG. Left ventricular infarct size assessed with 0.1 mmol/kg of gadobenate dimeglumine correlates with that assessed with 0.2 mmol/kg of gadopentetate dimeglumine. J Comput Assist Tomogr. 2009;33(3):328-333.

Walsh TF, Dall'Armellina E, Chughtai H, Morgan TM, Ntim W, Link KM, Hamilton CA, Kitzman DW, Hundley WG. Adverse effect of increased left ventricular wall thickness on five year outcomes of patients with negative dobutamine stress. J Cardiovasc Magn Reson. 2009;11():article 25.

Puntawagkoon C, Kitzman DW, Kritchevsky SB, Hamilton CA, Nicklas B, Leng X, Brubaker PH, Hundley WG. Exercise limb blood flow is reduced despite adequate cardiac output in elderly patients with heart failure [abstract]. J Card Fail. 2009;15(6 Suppl 1):S69.

Jeevanantham V, Chughtai HL, Little WC, Morgan TM, Kitzman DW, Ntim WO, Hamilton CA, Hundley WG. Aging affects the response of the left atrium to adrenergic stress [abstract]. Circulation. 2009;120(18 Suppl):S493.

Chaosuwannakit N, D'Agostino R Jr, Hamilton CA, Lane KS, Ntim WO, Lawrence J, Melin SA, Ellis LR, Torti FM, Little WC, Hundley WG. Subclinical cardiovascular toxicity of anthracyclines identified with cardiovascular magnetic resonance imaging [abstract]. Circulation. 2009;120(18 Suppl):S299.

Puntawangkoon C, Kitzman DW, Kritchevsky SB, Hamilton CA, Nicklas B, Leng X, Brubaker PH, Hundley WG. Reduced peripheral arterial blood flow with preserved cardiac output during submaximal bicycle exercise in elderly heart failure. J Cardiovasc Magn Reson. 2009;11(1):article 48.

Chughtai HL, Morgan TM, Ding JZ, Brinkley TE, Rocco M, Hamilton CA, Hundley WG. Renal sinus fat influences the number of medications needed to regulate blood pressure in patients with hypertension [abstract]. Circulation. 2009;120(18 Suppl 2):S1017.

Miller CD, Hwang W, Case D, Lefebvre C, Hiestand B, Diercks DB, Hamilton CA, Harper EN, Hoekstra JW, Hundley WG. Stress cardiac MRI in an observation unit setting reduces index hospitalization cost in ED patients with chest pain at intermediate risk for acute coronary syndromes [abstract]. Circulation. 2009;120(18 Suppl 2):S337.

Wallace EL, Morgan TM, Walsh TF IV, Dall'Armellina E, Ntim W, Hamilton CA, Hundley WG. The utility of dobutamine cardiovascular magnetic resonance results for identifying cardiac prognosis in women [abstract]. J Am Coll Cardiol. 2008;51(10 Suppl A):A162-A163.

Hundley G, Hamilton C, Lane K, Morgan T, Torti F, inventors; Wake Forest University Health Sciences, assignee. Non-invasive imaging for determination of global tissue characteristics. United States patent US 7,333,845. 2008 Feb 19. 2008;():.

Kemper KJ, Hamilton CA, McLean TW, Lovato J. Impact of music on pediatric oncology outpatients. Pediatr Res. 2008;64(1):105-109.

Dall'Armellina E, Morgan TM, Ntim W, Carr JJ, Hamilton CA, Hoyle J, Clark H, Clark P, Link KM, Case D, Hundley WG, et al. Prediction of cardiac events in patients with reduced left ventricular ejection fraction with dobutamine cardiovascular magnetic resonance assessment of wall motion score index. J Am Coll Cardiol. 2008;52(4):279-286.

Kumar R, McNeal GR, Stewart KC, Charonko JJ, Pierrakos O, Vlachos PP, Ntim WO, Hundley G, Hamilton CA, Little WC. Phase contrast imaging: a novel way of assessing left ventricular diastolic function [abstract]. J Cardiovasc Magn Reson. 2008;10(Suppl 1):Abstr 225.

Mandapaka S, Little W, Dall'Armelina E, Morgan T, Bertoni A, Hamilton C, Hundley WG. Is heightened vascular stiffness a predictor of future acute pulmonary edema [abstract]. Circulation. 2008;118(18 Suppl 2):S691.

Kemper KJ, Hamilton C. Live harp music reduces activity and increases weight gain in stable premature infants [letter]. J Altern Complement Med. 2008;14(10):1185-1186.

Hundley G, Hamilton C, inventors; Wake Forest University Health Sciences, assignee. Cardiac diagnostics using wall motion and perfusion cardiac MRI imaging and systems for cardiac diagnostics. Chinese patent CN ZL0382105.0. 2008 July 16. 2008;():.

Hamilton C, Hundley WG, inventors; Wake Forest University Health Sciences, assignee. Cardiac diagnostics using wall motion and perfusion cardiac MRI imaging systems for cardiac diagnostics. United States patent US 7,463,919. 2008 Dec 9. 2008;():.

Hundley WG, Bayram E, Hamilton CA, Hamilton EA, Morgan TM, Darty SN, Stewart KP, Link KM, Herrington DM, Kitzman DW. Leg flow-mediated arterial dilation in elderly patients with heart failure and normal left ventricular ejection fraction. Am J Physiol Heart Circ Physiol. 2007;292(3):H1427-1434.

Dall'Armellina E, Hamilton CA, Hundley WG. Assessment of blood flow and valvular heart disease using phase-contrast cardiovascular magnetic resonance. Echocardiography. 2007;24(2):207-216.

Dall'Armellina E, Morgan TM, Clark H, Mandapaka S, Clark P, Carr JJ, Ntim W, Hamilton CA, Hoyle J, Link KM, Hundley WG. Prediction of cardiac events in patients with reduced left ventricular ejection fraction using dobutamine cardiovascular magnetic resonance assessment of wall motion score index [abstract]. J Am Coll Cardiol. 2007;49(9 Suppl 1):204A.

Tumkosit M, Martin CG, Bayram E, Morgan TM, Lane KS, Rerkpattanapipat P, Hamilton CA, Link KM, Hundley WG. Left ventricular spherical remodeling and apical myocardial relaxation: cardiovascular MR imaging measurement of myocardial segments. Radiology. 2007;244(2):411-418.

Kemper KJ, Hamilton C, Atkinson M. Heart rate variability: impact of differences in outlier identification and management strategies on common measures in three clinical populations. Pediatr Res. 2007;62(3):337-342.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Biomedical Engineering

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