Profile

Robert E. Hampson, Ph.D.Wake Forest School of Medicine

Robert E. Hampson, Ph.D.

Associate Professor,

Contact Information

Academic: 336-716-8541 | Department: 336-716-8541

Email: rhampson@wakehealth.edu

Education & Training

  • B.S., University of Texas-San Antonio , 1979
  • M.S., Lehigh University , 1981
  • Ph.D., Wake Forest University , 1988
  • Fellowship, WFU School of Medicine, 1989

Memberships

  • Society for Neuroscience
  • Sleep Research Society
  • Int'l Cannabinoid Society
Robert E. Hampson, Ph.D.

Robert E. Hampson, Ph.D.

Associate Professor, Physiology & Pharmacology
Center for Comparative Medicine Research

Research Interests

cognition/learning, computer science, drugs/therapeutic agents pharm, mental disorders/psychiatry/ps, neurosciences/behavior, statistics/mathematics, substance abuse

Contact Information

Academic: 336-716-8541 | Department: 336-716-8541

Email: rhampson@wakehealth.edu

Recent Publications

Santos L, Opris I, Hampson R, Godwin DW, Gerhardt G, Deadwyler S. Functional dynamics of primate cortico-striatal networks during volitional movements. Front Syst Neurosci. 2014;8():27.

Marmarelis VZ, Shin DC, Song D, Hampson RE, Deadwyler SA, Berger TW. On parsing the neural code in the prefrontal cortex of primates using principal dynamic modes. J Comput Neurosci. 2014;36(3):321-337.

Song D, Harway M, Marmarelis VZ, Hampson RE, Deadwyler SA, Berger TW. Extraction and restoration of hippocampal spatial memories with non-linear dynamical modeling. Front Syst Neurosci. 2014;8():97.

Opris I, Fuqua JL, Gerhardt GA, Hampson RE, Deadwyler SA. Prefrontal cortical recordings with biomorphic MEAs reveal complex columnar-laminar microcircuits for BCI/BMI implementation. J Neurosci Methods. 2014;():.

Fetterhoff D, Opris I, Simpson SL, Deadwyler SA, Hampson RE, Kraft RA. Multifractal analysis of information processing in hippocampal neural ensembles during working memory under delta-tetrahydrocannabinol administration. J Neurosci Methods. 2014;():.

Song D, Chan RH, Robinson BS, Marmarelis VZ, Opris I, Hampson RE, Deadwyler SA, Berger TW. Identification of functional synaptic plasticity from spiking activities using nonlinear dynamical modeling. J Neurosci Methods. 2014;():.

Porrino LJ, Hampson RE, Opris I, Deadwyler SA. Acute cocaine induced deficits in cognitive performance in rhesus macaque monkeys treated with baclofen. Psychopharmacology (Berl). 2013;225(1):105-114.

Marmarelis VZ, Shin DC, Song D, Hampson RE, Deadwyler SA, Berger TW. Nonlinear modeling of dynamic interactions within neuronal ensembles using Principal Dynamic Modes. J Comput Neurosci. 2013;34(1):73-87.

McQuail JA, Davis KN, Miller F, Hampson RE, Deadwyler SA, Howlett AC, Nicolle MM. Hippocampal G alpha q/11 but not G alpha o-coupled receptors are altered in aging. Neuropharmacology. 2013;70():63-73.

Opris I, Santos L, Gerhardt GA, Song D, Berger TW, Hampson RE, Deadwyler SA. Prefrontal cortical microcircuits bind perception to executive control. Sci Rep. 2013;3():2285.

Song D, Wang H, Tu CY, Marmarelis VZ, Hampson RE, Deadwyler SA, Berger TW. Identification of sparse neural functional connectivity using penalized likelihood estimation and basis functions. J Comput Neurosci. 2013;35(3):335-357.

Hampson RE, Song D, Opris I, Santos LM, Shin DC, Gerhardt GA, Marmarelis VZ, Berger TW, Deadwyler SA. Facilitation of memory encoding in primate hippocampus by a neuroprosthesis that promotes task-specific neural firing. J Neural Eng. 2013;10(6):066013.

Deadwyler SA, Berger TW, Sweatt AJ, Song D, Chan RH, Opris I, Gerhardt GA, Marmarelis VZ, Hampson RE. Donor/recipient enhancement of memory in rat hippocampus. Front Syst Neurosci. 2013;7():120.

Linville C, Mintz A, Hampson R, Deadwyler S, Peiffer A. Changes in FDG-PET uptake during a delayed match to samplememory task [abstract]. Neuro Oncol. 2013;15(Suppl 3):95.

Santos L, Opris I, Fuqua J, Hampson RE, Deadwyler SA. A novel tetrode microdrive for simultaneous multi-neuron recording from different regions of primate brain. J Neurosci Methods. 2012;205(2):368-374.

Berger TW, Song D, Chan RHM, Marmarelis VZ, LaCoss J, Wills J, Hampson RE, Deadwyler SA, Granacki JJ. A hippocampal cognitive prosthesis: multi-input, multi-output nonlinear modeling and VLSI implementation. IEEE Trans Neural Syst Rehabil Eng. 2012;20(2):198-211.

Hampson RE, Song D, Chan RHM, Sweatt AJ, Riley MR, Gerhardt GA, Shin DC, Marmarelis VZ, Berger TW, Deadwyler SA. A nonlinear model for hippocampal cognitive prosthesis: memory facilitation by hippocampal ensemble stimulation. IEEE Trans Neural Syst Rehabil Eng. 2012;20(2):184-197.

Hampson RE, Song D, Chan RHM, Sweatt AJ, Riley MR, Goonawardena AV [sic] [Goonawardane AV], Marmarelis VZ, Gerhardt GA, Berger TW, Deadwyler SA. Closing the loop for memory prosthesis: detecting the role of hippocampal neural ensembles using nonlinear models. IEEE Trans Neural Syst Rehabil Eng. 2012;20(4):510-525.

Hampson RE, Gerhardt GA, Marmarelis V, Song D, Opris I, Santos L, Berger TW, Deadwyler SA. Facilitation and restoration of cognitive function in primate prefrontal cortex by a neuroprosthesis that utilizes minicolumn-specific neural firing. J Neural Eng. 2012;9(5):056012.

Berger T, Song D, Chan R, Shin D, Marmarelis V, Hampson R, Sweatt A, Heck C, Liu C, Wills J, Lacoss J, Granacki J, Gerhardt G, Deadwyler S. Role of the hippocampus in memory formation: restorative encoding memory integration neural device as a cognitive neural prosthesis. IEEE Pulse. 2012;3(5):17-22.

Opris I, Fuqua JL, Huettl PF, Gerhardt GA, Berger TW, Hampson RE, Deadwyler SA. Closing the loop in primate prefrontal cortex: inter-laminar processing. Front Neural Circuits. 2012;6():88.

Opris I, Hampson RE, Gerhardt GA, Berger TW, Deadwyler SA. Columnar processing in primate pFC: evidence for executive control microcircuits. J Cogn Neurosci. 2012;24(12):2334-2347.

Linville C, Hampson R, Deadwyler S, Peiffer A. Exploring late effects of brain irradiation with a delayed match to sample paradigm [abstract]. Neuro Oncol. 2012;14(Suppl 6):62.

Marmarelis VZ, Shin DC, Hampson RE, Deadwyler SA, Song D, Berger TW. Design of optimal stimulation patterns for neuronal ensembles based on Volterra-type hierarchical modeling. J Neural Eng. 2012;9(6):066003.



Hampson RE, Porrino LJ, Opris I, Stanford T, Deadwyler SA. Effects of cocaine rewards on neural representations of cognitive demand in nonhuman primates. Psychopharmacology (Berl). 2011;213(1):105-118.

Opris I, Hampson RE, Stanford TR, Gerhardt GA, Deadwyler SA. Neural activity in frontal cortical cell layers: evidence for columnar sensorimotor processing. J Cogn Neurosci. 2011;23(6):1507-1521.

Hampson RE, Simeral JD, Berger TW, Song D, Chan RHM, Marmarelis VZ, Deadwyler SA. Cognitively relevant recoding in hippocampus: beneficial feedback of ensemble codes in a closed loop paradigm In: Vertes RP, Stackman RW, eds. Electrophysiological recording techniques. Totowa (NJ): Humana Press;2011: 215-240.

Goonawardena AV [sic] [Goonawardane AV], Riedel G, Hampson RE. Cannabinoids alter spontaneous firing, bursting, and cell synchrony of hippocampal principal cells. Hippocampus. 2011;21(5):520-531.

Hampson RE, Sweatt AJ, Goonawardena AV [sic] [Goonawardane AV], Song D, Chan RHM, Marmarelis VZ, Berger TW, Deadwyler SA. Memory encoding in hippocampal ensembles is negatively influenced by cannabinoid CB1 receptors. Behav Pharmacol. 2011;22(4):335-346.

Howlett AC, Reggio PH, Childers SR, Hampson RE, Ulloa NM, Deutsch DG. Endocannabinoid tone versus constitutive activity of cannabinoid receptors. Br J Pharmacol. 2011;163(7):1329-1343.

Goonawardena AV [sic] [Goonawardane AV], Sesay J, Sexton CA, Riedel G, Hampson RE. Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus. Neuropharmacology. 2011;61(5-6):1016-1025.

Berger TW, Hampson RE, Song D, Goonawardena A [sic] [Goonawardane A], Marmarelis VZ, Deadwyler SA. A cortical neural prosthesis for restoring and enhancing memory. J Neural Eng. 2011;8(4):046017.

Hampson RE, Porrino LJ, Opris I, Stanford TE, Deadwyler SA. Effects of cocaine on neural substrates of cognitive demand in nonhuman primates [abstract]. Behav Pharmacol. 2011;22(Suppl A):e12.

Chan RH, Song D, Goonawardena AV [sic] [Goonawardane AV], Bough S, Sesay J, Hampson RE, Deadwyler SA, Berger TW. Tracking the changes of hippocampal population nonlinear dynamics in rats learning a memory-dependent task. Conf Proc IEEE Eng Med Biol Soc. 2011;2011():3326-3329.

Song D, Chan RH, Marmarelis VZ, Hampson RE, Deadwyler SA, Berger TW. Estimation and statistical validation of event-invariant nonlinear dynamic models of hippocampal CA3-CA1 population activities. Conf Proc IEEE Eng Med Biol Soc. 2011;2011():3330-3333.

Hampson RE, Marmaralis V, Shin DC, Gerhardt GA, Song D, Chan RH, Sweatt AJ, Granacki J, Berger TW, Deadwyler SA. Restorative encoding memory integrative neural device: 'REMIND'. Conf Proc IEEE Eng Med Biol Soc. 2011;2011():3338-3341.

Marmarelis VZ, Shin DC, Song D, Hampson RE, Deadwyler SA, Berger TW. Dynamic nonlinear modeling of interactions between neuronal ensembles using principal dynamic modes. Conf Proc IEEE Eng Med Biol Soc. 2011;2011():3334-3337.

Robinson L, Goonawardena AV, Pertwee R, Hampson RE, Platt B, Riedel G. WIN55,212-2 induced deficits in spatial learning are mediated by cholinergic hypofunction. Behav Brain Res. 2010;208(2):584-592.


Goonawardena AV [sic] [Goonawardane AV], Robinson L, Hampson RE, Riedel G. Cannabinoid and cholinergic systems interact during performance of a short-term memory task in the rat. Learn Mem. 2010;17(10):502-511.

Goonawardena AV [sic] [Goonawardane AV], Robinson L, Riedel G, Hampson RE. Recruitment of hippocampal neurons to encode behavioral events in the rat: alterations in cognitive demand and cannabinoid exposure. Hippocampus. 2010;20(9):1083-1094.

Hampson RE, Espana RA, Rogers GA, Porrino LJ, Deadwyler SA. Mechanisms underlying cognitive enhancement and reversal of cognitive deficits in nonhuman primates by the ampakine CX717. Psychopharmacology (Berl). 2009;202(1-3):355-369.

Zanos TP, Hampson RE, Deadwyler SE, Berger TW, Marmarelis VZ. Boolean modeling of neural systems with point-process inputs and outputs. Part II: application to the rat hippocampus. Ann Biomed Eng. 2009;37(8):1668-1682.

Hampson RE, Collins V, Deadwyler SA. A wireless recording system that utilizes Bluetooth technology to transmit neural activity in freely moving animals. J Neurosci Methods. 2009;182(2):195-204.


Song D, Chan RHM, Marmarelis VZ, Hampson RE, Deadwyler SA, Berger TW. Nonlinear modeling of neural population dynamics for hippocampal prostheses. Neural Netw. 2009;22(9):1340-1351.

Hampson RE, Deadwyler SA. Neural population recording in behaving animals: constituents of a neural code for behavioral decisions In: Holscher C, Munk M, eds. Information processing by neuronal populations. New York: Cambridge University Press;2009: 74-94.

Song D, Chan RH, Marmarelis VZ, Hampson RE, Deadwyler SA, Berger TW. Sparse generalized Laguerre-Volterra model of neural population dynamics. Conf Proc IEEE Eng Med Biol Soc. 2009;2009():4555-4558.

Deadwyler SA, Hampson RE. Endocannabinoids modulate encoding of sequential memory in the rat hippocampus. Psychopharmacology (Berl). 2008;198(4):577-586.

Robinson L, McKillop-Smith S, Ross NL, Pertwee RG, Hampson RE, Platt B, Riedel G. Hippocampal endocannabinoids inhibit spatial learning and limit spatial memory in rats. Psychopharmacology (Berl). 2008;198(4):551-563.

Zanos TP, Courelis SH, Berger TW, Hampson RE, Deadwyler SA, Marmarelis VZ. Nonlinear modeling of causal interrelationships in neuronal ensembles. IEEE Trans Neural Syst Rehabil Eng. 2008;16(4):336-352.

Opris I, Hampson RE, Long J, Ramirez S, Todd M, Dunlap M, Stanford TR, Gerhardt GA, Deadwyler SA. Columnar processing in monkey prefrontal cortical neurons for juice vs. cocaine reinforcement [abstract]. Soc Neurosci Abstr. 2008;2008(Neuroscience Meeting Planner):.

Deadwyler S, Hampson R, inventors; Wake Forest University Health Sciences, assignee. Wireless systems and methods for the detection of neural events using onboard processing. United States patent US 7,460,904. 2008 Dec 2. 2008;():.

Song D, Chan RHM, Marmarelis VZ, Hampson RE, Deadwyler SA, Berger TW. Nonlinear dynamic modeling of spike train transformations for hippocampal-cortical prostheses. IEEE Trans Biomed Eng. 2007;54(6 Pt 1):1053-1066.

Deadwyler SA, Goonawardena AV, Hampson RE. Short-term memory is modulated by the spontaneous release of endocannabinoids: evidence from hippocampal population codes. Behav Pharmacol. 2007;18(5-6):571-580.

Robinson L, Goonawardena AV, Pertwee RG, Hampson RE, Riedel G. The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats. Br J Pharmacol. 2007;151(5):688-700.


Hampson RE. Cannabinoids alter neuronal representation of task-specific information [abstract]. Behav Pharmacol. 2007;18(Suppl 1):S9-S10.


Deadwyler SA, Porrino LJ, Daunais JB, Miller M, Hanlon CA, Morgan AR, Gill KE, Long J, Ramirez S, Todd M, Hampson RE. Evidence for the differential effects of modafinil and the ampakine CX717 on task-related brain glucose metabolism in sleep-deprived monkeys [abstract]. Soc Neurosci Abstr. 2006;2006(Abstr Viewer):.

Hampson R, Porrino LJ, Daunais JB, Miller M, Hanlon CA, Morgan AR, Gill KE, Long J, Ramirez S, Todd M, Deadwyler SA. Sleep deprivation disrupts brain glucose utilization and performance on high vs. low cognitive load trials during a delayed-match-to-sample (DMS) task in nonhuman primates [abstract]. Soc Neurosci Abstr. 2006;2006(Abstr Viewer):.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Physiology & Pharmacology

Robert E. Hampson, Ph.D.

Robert E. Hampson, Ph.D.

Associate Professor, Physiology & Pharmacology
Center for Comparative Medicine Research

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