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Ashok N.  Hegde, D.Phil.

Ashok N. Hegde, D.Phil.

Associate Professor, Neurobiology & Anatomy
Contact Information
Office:
336-716-1372
Education & Training
  PhD Free Standing Institute-India 1990
Fellowship Neurobiology Columbia University College Physicians & Surgeons 1994
Ashok N.  Hegde, D.Phil.

Ashok N. Hegde, D.Phil.

Associate Professor, Neurobiology & Anatomy
Contact Information
Office:
336-716-1372
Research Interests
cognition/learning , neurosciences/behavior
Recent Publications
Hegde AN, Upadhya SC. Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease. Biochim Biophys Acta. 2011; 1809(2):128-140.

Upadhya SC, Smith TK, Brennan PA, Mychaleckyj JC, Hegde AN. Expression profiling reveals differential gene induction underlying specific and non-specific memory for pheromones in mice. Neurochem Int. 2011; 59(6):787-803.

Ding L, Styblo M, Drobna Z, Hegde A. The mRNA expression level of the longest RGS4 splice variant is associated with single nucleotide polymorphisms [abstract]. Soc Neurosci Abstr. 2011; 2011(Neuroscience Meeting Planner):.

Hegde AN. Ubiquitin-dependent protein degradation. In: Mander L, Lui H-W, eds. Comprehensive natural products II: chemistry and biology, vol 5. Oxford (England): Elsevier; 2010: 699-752.

Hegde AN. The ubiquitin-proteasome pathway and synaptic plasticity. Learn Mem. 2010; 17(7):314-327.

Nesterova S, Upadhya S, Hegde AN. Blockade of transcription by proteasome inhibition during maintenance of late phase long-term potentiation [abstract]. Soc Neurosci Abstr. 2010; 2010(Neuroscience Meeting Planner):.

Hegde AN, Dong C. Proteasome inhibition enhances the induction of late phase long-term potentiation by stabilizing newly translated proteins [abstract]. Soc Neurosci Abstr. 2010; 2010(Neuroscience Meeting Planner):.


Hedge AN. Ubiquitin-proteasome system and plasticity. In: Squire LR, ed. Encyclopedia of neuroscience, vol 10. Berlin: Elsevier Academic Press; 2009: 1-9.

Dong C, Godwin DW, Brennan PA, Hegde AN. Protein kinase Calpha mediates a novel form of plasticity in the accessory olfactory bulb. Neuroscience. 2009; 163(3):811-824.

Upadhya SC, Smith TK, Hegde AN. Protein kinase C-mediated phosphorylation is critical for CREB repressor ubiquitination during induction of long-term facilitation [abstract]. Soc Neurosci Abstr. 2009; 2009(Neuroscience Meeting Planner):.

Hegde AN, Godwin DW, Brennan PA, Dong C. Coincidence detection by protein kinase Calpha in the accessory olfactory bulb suggests a model for a novel form of synaptic plasticity underlying single-trial learning [abstract]. Soc Neurosci Abstr. 2009; 2009(Neuroscience Meeting Planner):.

Dong C, Upadhya SC, Ding L, Smith TK, Hegde AN. Proteasome inhibition enhances the induction and impairs the maintenance of late-phase long-term potentiation. Learn Mem. 2008; 15(5):335-347.

Skinner CB, Upadhya SC, Smith TK, Turner CP, Hegde AN. Signal transduction and gene expression in cultured accessory olfactory bulb neurons. Neuroscience. 2008; 157(2):340-348.

Ding L, Hegde A. RGS4 splice variants are differentially expressed in dorsolateral prefrontal cortex of schizophrenic and bipolar disorder patients [abstract]. Soc Neurosci Abstr. 2008; 2008(Neuroscience Meeting Planner):.

Hegde AN. Proteolysis and synaptic plasticity. In: Sweatt JD, Byrne JH, eds. Learning and memory: a comprehensive reference, vol 4: molecular mechanisms of memory. San Diego: Elsevier; 2008: 525-546.


Hegde AN, Upadhya SC. The ubiquitin-proteasome pathway in health and disease of the nervous system. Trends Neurosci. 2007; 30(11):587-595.

Upadhya SC, Hegde AN. Role of the ubiquitin proteasome system in Alzheimer's disease. BMC Biochem. 2007; 8(Suppl 1):S12.

Ding L, Mychaleckyj JC, Hegde A. Splice variants of regulator of G-protein signaling RGS4 in human and murine brain [abstract]. Soc Neurosci Abstr. 2006; 2006(Abstr Viewer):.

Hegde AN, Upadhya SC, Ding L, Smith TK, Dong C. The proteasome plays differential spatial and temporal roles in late phase long-term potentiation [abstract]. Soc Neurosci Abstr. 2006; 2006(Abstr Viewer):.

Skinner CB, Hegde AN. Expression of genes encoding signaling molecules in the female mouse accessory olfactory bulb [abstract]. Soc Neurosci Abstr. 2006; 2006(Abstr Viewer):.

Upadhya SC, Smith TK, Hegde AN. Induction and nuclear translocation of a proteasome regulatory subunit during long-term memory [abstract]. Soc Neurosci Abstr. 2006; 2006(Abstr Viewer):.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Last Updated 5/5/2012
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