Scott Edwards Hemby, Ph.D.Wake Forest School of Medicine

Scott Edwards Hemby, Ph.D.


Contact Information

Academic: 336-716-8620 | Department: 336-716-8620


Education & Training

  • B.A., Barton College-Wilson , 1987
  • M.A., Emory University , 1990
  • Ph.D., Wake Forest University , 1995
  • Internship, Emory University, 1990
  • Internship, WFU School of Medicine, 1995
  • Fellowship, University of Pennsylvania Sch, 1998


  • Research Society On Alcoholism
  • Society for Neuroscience
Scott Edwards Hemby, Ph.D.

Scott Edwards Hemby, Ph.D.

Professor, Physiology & Pharmacology
WFU Primate Center
Psychiatry and Behavioral Medicine
Translational Science Institute

Research Interests

aids, degenerative disorders, genomics and proteomics, immunology/allergy/inflammatio, mental disorders/psychiatry/ps, molecular biology/molecular me, neurosciences/behavior, substance abuse

Contact Information

Academic: 336-716-8620 | Department: 336-716-8620


Recent Publications

Bough KJ, Amur S, Lao G, Hemby SE, Tannu NS, Kampman KM, Schmitz JM, Martinez D, Merchant KM, Green C, Sharma J, Dougherty AH, Moeller FG. Biomarkers for the development of new medications for cocaine dependence. Neuropsychopharmacology. 2014;39(1):202-219.

Burnett EJ, Grant KA, Davenport AT, Hemby SE, Friedman DP. The effects of chronic ethanol self-administration on hippocampal 5-HT1A receptors in monkeys. Drug Alcohol Depend. 2014;136():135-142.

Willard SL, Hemby SE, Register TC, McIntosh S, Shively CA. Altered expression of glial and synaptic markers in the anterior hippocampus of behaviorally depressed female monkeys. Neurosci Lett. 2014;563():1-5.

Daunais JB, Davenport AT, Helms CM, Gonzales SW, Hemby SE, Friedman DP, Farro JP, Baker EJ, Grant KA. Monkey alcohol tissue research resource: banking tissues for alcohol research. Alcohol Clin Exp Res. 2014;():.

Chen J, Repunte-Canonigo V, Kawamura T, Lefebvre C, Shin W, Howell LL, Hemby SE, Harvey BK, Califano A, Morales M, Koob GF, Sanna PP. Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor. Nat Commun. 2013;4():1955.

Acosta G, Freidman DR [sic] [Friedman DR], Grant KA, Hemby SE. Alternative splicing of AMPA subunits in prefrontal cortical fields of cynomolgus monkeys following chronic ethanol self-administration. Front Psychiatry. 2012;2():72.

Ginsberg SD, Hemby SE, Smiley JF. Expression profiling in neuropsychiatric disorders: emphasis on glutamate receptors in bipolar disorder. Pharmacol Biochem Behav. 2012;100(4):705-711.

Pattison LP, McIntosh S, Budygin EA, Hemby SE. Differential regulation of accumbal dopamine transmission in rats following cocaine, heroin and speedball self-administration. J Neurochem. 2012;122(1):138-146.

Burnett EJ, Darmon M, Grant KA, Friedman DP, Hemby SE. Ethanol-induced differential gene expression of 5-HT1A and YIF1B in hippocampal pyramidal and granule cells in cynomolgus macaques [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 1):259A.

Hemby SE, McCool B, Friedman DP, Helms CM. Ethanol-induced regulation of iGluR and GABAA subunit mRNAs in prefrontal fields of cynomolgus monkey [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 2):39A.

Pattison LP, Tannu NS, McIntosh S, Grigg AL, Hemby SE. Membrane proteomic analysis of rat nucleus accumbens following self-administration of cocaine, heroin and cocaine/heroin, 'speedball' combinations [abstract]. J Neurochem. 2012;122(Suppl 1):24-25.

Willard SL, Riddle DR, Forbes ME, Hemby SE, McIntosh S, Uberseder B, Shively CA. Cellular and molecular factors contributing to hippocampus size in an adult female monkey model of depression [abstract]. Soc Neurosci Abstr. 2012;2012(Neuroscience Meeting Planner):.

Pattison LP, Bonin KD, Hemby SE, Budygin EA. Speedball induced changes in electrically stimulated dopamine overflow in rat nucleus accumbens. Neuropharmacology. 2011;60(2-3):312-317.

Daunais JB, Davenport AT, Hemby SE, Friedman DP, Baker EJ, Grant KA. Monkey alcohol tissue research resource [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):123A.

Grant KA, Hemby SE. Prefrontal cortical glutamate and GABA gene expression in chronic ethanol self-administration in macaque monkeys [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):312A.

Hemby SE. Cocainomics: new insights into the molecular basis of cocaine addiction. J Neuroimmune Pharmacol. 2010;5(1):70-82.

Lynch WJ, Piehl KB, Acosta G, Peterson AB, Hemby SE. Aerobic exercise attenuates reinstatement of cocaine-seeking behavior and associated neuroadaptations in the prefrontal cortex. Biol Psychiatry. 2010;68(8):774-777.

Hemby SE, Tannu NS. Synaptic proteome of the hippocampal formation in rhesus monkeys [abstract]. J Neurochem. 2009;108(Suppl 1):80.

Hemby SE, McIntosh S, Egan K, Horman B, Co C, Parsons LH. Assessment of extracellular dopamine, serotonin, glutamate and GABA in nucleus accumbens and ventral tegmental area during cocaine [abstract]. J Neurochem. 2009;108(Suppl 1):126.

Egan K, Acosta G, Grant K, Hemby SE. Neurotrophic factor and receptor alterations in specific prefrontal cortical subregions following ethanol self-administration in monkeys [abstract]. Alcohol Clin Exp Res. 2009;33(6 Special Issue):206A.

Hemby SE. Proteomic profiling of cocaine addiction in the primate brain [abstract]. J Neurochem. 2009;110(Suppl 2):217.

Hemby SE, Tannu N. Modeling substance abuse for applications in proteomics. Methods Mol Biol. 2009;566():69-83.

Backes EN, Hemby SE. Contribution of ventral tegmental GABA receptors to cocaine self-administration in rats. Neurochem Res. 2008;33(3):459-467.

Egan K, Acosta G, Horman B, Friedman DP, Grant KA, Hemby SE. Alterations in ionotropic glutamate receptor subunit abundances in prefrontal cortex following ethanol self-administration in male cynomolgus monkeys [abstract]. Alcohol Clin Exp Res. 2008;32(6 Suppl 1):152A.

Hemby SE, Hanlon CA, Horman B, Sikoski P, Daunais J, Kraft R, Porrino LJ. MRI assessment of chronic antipsychotic administration in rhesus monkeys [abstract]. Soc Neurosci Abstr. 2008;2008(Neuroscience Meeting Planner):.

Tannu N, Mash DC, Hemby SE. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Mol Psychiatry. 2007;12(1):55-73.

Hemby SE. Role of glutamate in alcoholism: disease and treatment [abstract]. Alcohol Clin Exp Res. 2007;31(6 Suppl):261A.

Tannu NS, Hemby SE. De novo protein sequence analysis of Macaca mulatta. BMC Genomics. 2007;8():art. 270.

Hemby SE. Assessment of genome and proteome profiles in cocaine abuse. Prog Brain Res. 2006;158():173-195.

O'Connor JA, Hasenkamp W, Horman BM, Muly EC, Hemby SE. Region specific regulation of NR1 in rhesus monkeys following chronic antipsychotic drug administration. Biol Psychiatry. 2006;60(6):659-662.

Tannu NS, Hemby SE. Methods for proteomics in neuroscience. Prog Brain Res. 2006;158():41-82.

Hemby S. Mechanisms of transcriptional regulation in the alcoholic brain [abstract]. Alcohol Clin Exp Res. 2006;30(9 Suppl):76A.

Hemby S. Ethanol self-administration and the regulation of GABAA alpha subunit mRNAs in frontal corticol areas of cynomolgous monkeys [abstract]. Alcohol Clin Exp Res. 2006;30(9 Suppl):98A.

Hemby SE, O'Connor JA, Acosta G, Floyd D, Anderson N, McCool BA, Friedman D, Grant KA. Ethanol-induced regulation of GABA subunit mRNAs in prefrontal fields of cynomolgus monkeys. Alcohol Clin Exp Res. 2006;30(12):1978-1985.

Hemby SE, Tannu N, Mash DC, Howell LL. Quantitative proteomic profiling of cocaine's effects in the primate brain [abstract]. Neuropsychopharmacology. 2006;31(Suppl):S205.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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