Profile

Scott Edwards Hemby, Ph.D.

Scott Edwards Hemby, Ph.D.

Professor, Physiology & Pharmacology
Translational Science Institute
WFU Primate Center
Translational Science Institute
Psychiatry and Behavioral Medicine

Contact Information

Academic: 336-716-8620 | Department: 336-716-8620

Email: shemby@wakehealth.edu

Education & Training

  • B.A., Barton College-Wilson , 1987
  • Ph.D., Wake Forest University , 1995
  • M.A., Emory University , 1990
  • Internship, Emory University, 1990
  • Internship, WFU School of Medicine, 1995
  • Fellowship, University of Pennsylvania School of Medicine, 1998

Memberships

  • Research Society On Alcoholism
  • Society for Neuroscience
Scott Edwards Hemby, Ph.D.

Scott Edwards Hemby, Ph.D.

Professor, Physiology & Pharmacology Translational Science Institute
WFU Primate Center
Translational Science Institute
Psychiatry and Behavioral Medicine

Research Interests

drugs/therapeutic agents pharm, model development, molecular biology/molecular me, substance abuse

Contact Information

Academic: 336-716-8620 | Department: 336-716-8620

Email: shemby@wakehealth.edu

Recent Publications

Acosta G, Freidman DR [sic] [Friedman DR], Grant KA, Hemby SE. Alternative splicing of AMPA subunits in prefrontal cortical fields of cynomolgus monkeys following chronic ethanol self-administration. Front Psychiatry. 2012;2():72.

Ginsberg SD, Hemby SE, Smiley JF. Expression profiling in neuropsychiatric disorders: emphasis on glutamate receptors in bipolar disorder. Pharmacol Biochem Behav. 2012;100(4):705-711.

Pattison LP, McIntosh S, Budygin EA, Hemby SE. Differential regulation of accumbal dopamine transmission in rats following cocaine, heroin and speedball self-administration. J Neurochem. 2012;122(1):138-146.

Burnett EJ, Darmon M, Grant KA, Friedman DP, Hemby SE. Ethanol-induced differential gene expression of 5-HT1A and YIF1B in hippocampal pyramidal and granule cells in cynomolgus macaques [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 1):259A.

Hemby SE, McCool B, Friedman DP, Helms CM. Ethanol-induced regulation of iGluR and GABAA subunit mRNAs in prefrontal fields of cynomolgus monkey [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 2):39A.

Pattison LP, Tannu NS, McIntosh S, Grigg AL, Hemby SE. Membrane proteomic analysis of rat nucleus accumbens following self-administration of cocaine, heroin and cocaine/heroin, 'speedball' combinations [abstract]. J Neurochem. 2012;122(Suppl 1):24-25.

Willard SL, Riddle DR, Forbes ME, Hemby SE, McIntosh S, Uberseder B, Shively CA. Cellular and molecular factors contributing to hippocampus size in an adult female monkey model of depression [abstract]. Soc Neurosci Abstr. 2012;2012(Neuroscience Meeting Planner):.

Pattison LP, Bonin KD, Hemby SE, Budygin EA. Speedball induced changes in electrically stimulated dopamine overflow in rat nucleus accumbens. Neuropharmacology. 2011;60(2-3):312-317.

Daunais JB, Davenport AT, Hemby SE, Friedman DP, Baker EJ, Grant KA. Monkey alcohol tissue research resource [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):123A.

Grant KA, Hemby SE. Prefrontal cortical glutamate and GABA gene expression in chronic ethanol self-administration in macaque monkeys [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):312A.



Hemby SE. Cocainomics: new insights into the molecular basis of cocaine addiction. J Neuroimmune Pharmacol. 2010;5(1):70-82.


Lynch WJ, Piehl KB, Acosta G, Peterson AB, Hemby SE. Aerobic exercise attenuates reinstatement of cocaine-seeking behavior and associated neuroadaptations in the prefrontal cortex. Biol Psychiatry. 2010;68(8):774-777.

Hemby SE, Tannu NS. Synaptic proteome of the hippocampal formation in rhesus monkeys [abstract]. J Neurochem. 2009;108(Suppl 1):80.

Hemby SE, McIntosh S, Egan K, Horman B, Co C, Parsons LH. Assessment of extracellular dopamine, serotonin, glutamate and GABA in nucleus accumbens and ventral tegmental area during cocaine [abstract]. J Neurochem. 2009;108(Suppl 1):126.

Egan K, Acosta G, Grant K, Hemby SE. Neurotrophic factor and receptor alterations in specific prefrontal cortical subregions following ethanol self-administration in monkeys [abstract]. Alcohol Clin Exp Res. 2009;33(6 Special Issue):206A.

Hemby SE. Proteomic profiling of cocaine addiction in the primate brain [abstract]. J Neurochem. 2009;110(Suppl 2):217.

Hemby SE, Tannu N. Modeling substance abuse for applications in proteomics. Methods Mol Biol. 2009;566():69-83.

Backes EN, Hemby SE. Contribution of ventral tegmental GABA receptors to cocaine self-administration in rats. Neurochem Res. 2008;33(3):459-467.

Egan K, Acosta G, Horman B, Friedman DP, Grant KA, Hemby SE. Alterations in ionotropic glutamate receptor subunit abundances in prefrontal cortex following ethanol self-administration in male cynomolgus monkeys [abstract]. Alcohol Clin Exp Res. 2008;32(6 Suppl 1):152A.

Hemby SE, Hanlon CA, Horman B, Sikoski P, Daunais J, Kraft R, Porrino LJ. MRI assessment of chronic antipsychotic administration in rhesus monkeys [abstract]. Soc Neurosci Abstr. 2008;2008(Neuroscience Meeting Planner):.

Tannu N, Mash DC, Hemby SE. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Mol Psychiatry. 2007;12(1):55-73.


Hemby SE. Role of glutamate in alcoholism: disease and treatment [abstract]. Alcohol Clin Exp Res. 2007;31(6 Suppl):261A.

Tannu NS, Hemby SE. De novo protein sequence analysis of Macaca mulatta. BMC Genomics. 2007;8():art. 270.


Hemby SE. Assessment of genome and proteome profiles in cocaine abuse. Prog Brain Res. 2006;158():173-195.

O'Connor JA, Hasenkamp W, Horman BM, Muly EC, Hemby SE. Region specific regulation of NR1 in rhesus monkeys following chronic antipsychotic drug administration. Biol Psychiatry. 2006;60(6):659-662.

Tannu NS, Hemby SE. Methods for proteomics in neuroscience. Prog Brain Res. 2006;158():41-82.

Hemby S. Mechanisms of transcriptional regulation in the alcoholic brain [abstract]. Alcohol Clin Exp Res. 2006;30(9 Suppl):76A.

Hemby S. Ethanol self-administration and the regulation of GABAA alpha subunit mRNAs in frontal corticol areas of cynomolgous monkeys [abstract]. Alcohol Clin Exp Res. 2006;30(9 Suppl):98A.

Hemby SE, O'Connor JA, Acosta G, Floyd D, Anderson N, McCool BA, Friedman D, Grant KA. Ethanol-induced regulation of GABA subunit mRNAs in prefrontal fields of cynomolgus monkeys. Alcohol Clin Exp Res. 2006;30(12):1978-1985.

Hemby SE, Tannu N, Mash DC, Howell LL. Quantitative proteomic profiling of cocaine's effects in the primate brain [abstract]. Neuropsychopharmacology. 2006;31(Suppl):S205.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Physiology & Pharmacology

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