Profile

Scott Edwards Hemby, Ph.D.

Scott Edwards Hemby, Ph.D.

Professor, Physiology & Pharmacology
Translational Science Institute
WFU Primate Center
Psychiatry & Behavioral Medicine
Translational Science Institute
Contact Information
Office:
336-716-8620
Fax:
336-716-8501
Email: shemby@wakehealth.edu
Education & Training
  BA Barton College-Wilson 1987
  MA Emory University 1990
  PhD Wake Forest University 1995
Internship Emory University 1990
  WFU School of Medicine 1995
Fellowship University of Pennsylvania School of Medicine 1998
Memberships
Research Society On Alcoholism
Society for Neuroscience
Scott Edwards Hemby, Ph.D.

Scott Edwards Hemby, Ph.D.

Professor, Physiology & Pharmacology
Translational Science Institute
WFU Primate Center
Psychiatry & Behavioral Medicine
Translational Science Institute
Contact Information
Office:
336-716-8620
Fax:
336-716-8501
Email: shemby@wakehealth.edu
Research Interests
model development , molecular biology/molecular me , substance abuse
Recent Publications
Acosta G, Freidman DR [sic] [Friedman DR], Grant KA, Hemby SE. Alternative splicing of AMPA subunits in prefrontal cortical fields of cynomolgus monkeys following chronic ethanol self-administration. Front Psychiatry. 2012; 2():72.

Ginsberg SD, Hemby SE, Smiley JF. Expression profiling in neuropsychiatric disorders: emphasis on glutamate receptors in bipolar disorder. Pharmacol Biochem Behav. 2012; 100(4):705-711.

Pattison LP, Bonin KD, Hemby SE, Budygin EA. Speedball induced changes in electrically stimulated dopamine overflow in rat nucleus accumbens. Neuropharmacology. 2011; 60(2-3):312-317.

Daunais JB, Davenport AT, Hemby SE, Friedman DP, Baker EJ, Grant KA. Monkey alcohol tissue research resource [abstract]. Alcohol Clin Exp Res. 2011; 35(6 Suppl):123A.

Grant KA, Hemby SE. Prefrontal cortical glutamate and GABA gene expression in chronic ethanol self-administration in macaque monkeys [abstract]. Alcohol Clin Exp Res. 2011; 35(6 Suppl):312A.

Tannu NS, Howell LL, Hemby SE. Integrative proteomic analysis of the nucleus accumbens in rhesus monkeys following cocaine self-administration. Mol Psychiatry. 2010; 15(2):185-203.

Abdolahi A, Acosta G, Breslin FJ, Hemby SE, Lynch WJ. Incubation of nicotine seeking is associated with enhanced protein kinase A-regulated signaling of dopamine- and cAMP-regulated phosphoprotein of 32 kDa in the insular cortex. Eur J Neurosci. 2010; 31(4):733-741.

Hemby SE. Cocainomics: new insights into the molecular basis of cocaine addiction. J Neuroimmune Pharmacol. 2010; 5(1):70-82.

Acosta G, Hasenkamp W, Daunais JB, Friedman DP, Grant KA, Hemby SE. Ethanol self-administration modulation of NMDA receptor subunit and related synaptic protein mRNA expression in prefrontal cortical fields in cynomolgus monkeys. Brain Res. 2010; 1318():144-154.

Lynch WJ, Piehl KB, Acosta G, Peterson AB, Hemby SE. Aerobic exercise attenuates reinstatement of cocaine-seeking behavior and associated neuroadaptations in the prefrontal cortex. Biol Psychiatry. 2010; 68(8):774-777.

Hemby SE, Tannu NS. Synaptic proteome of the hippocampal formation in rhesus monkeys [abstract]. J Neurochem. 2009; 108(Suppl 1):80.

Hemby SE, McIntosh S, Egan K, Horman B, Co C, Parsons LH. Assessment of extracellular dopamine, serotonin, glutamate and GABA in nucleus accumbens and ventral tegmental area during cocaine [abstract]. J Neurochem. 2009; 108(Suppl 1):126.

Egan K, Acosta G, Grant K, Hemby SE. Neurotrophic factor and receptor alterations in specific prefrontal cortical subregions following ethanol self-administration in monkeys [abstract]. Alcohol Clin Exp Res. 2009; 33(6 Special Issue):206A.

Hemby SE. Proteomic profiling of cocaine addiction in the primate brain [abstract]. J Neurochem. 2009; 110(Suppl 2):217.

Hemby SE, Tannu N. Modeling substance abuse for applications in proteomics. Methods Mol Biol. 2009; 566():69-83.

Backes EN, Hemby SE. Contribution of ventral tegmental GABA receptors to cocaine self-administration in rats. Neurochem Res. 2008; 33(3):459-467.

Egan K, Acosta G, Horman B, Friedman DP, Grant KA, Hemby SE. Alterations in ionotropic glutamate receptor subunit abundances in prefrontal cortex following ethanol self-administration in male cynomolgus monkeys [abstract]. Alcohol Clin Exp Res. 2008; 32(6 Suppl 1):152A.

Hemby SE, Hanlon CA, Horman B, Sikoski P, Daunais J, Kraft R, Porrino LJ. MRI assessment of chronic antipsychotic administration in rhesus monkeys [abstract]. Soc Neurosci Abstr. 2008; 2008(Neuroscience Meeting Planner):.

Tannu N, Mash DC, Hemby SE. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Mol Psychiatry. 2007; 12(1):55-73.

O'Connor JA, Muly EC, Arnold SE, Hemby SE. AMPA receptor subunit and splice variant expression in the DLPFC of schizophrenic subjects and rhesus monkeys chronically administered antipsychotic drugs. Schizophr Res. 2007; 90(1-3):28-40.

Hemby SE. Role of glutamate in alcoholism: disease and treatment [abstract]. Alcohol Clin Exp Res. 2007; 31(6 Suppl):261A.

Tannu NS, Hemby SE. De novo protein sequence analysis of Macaca mulatta. BMC Genomics. 2007; 8():art. 270.

O'Connor JA, Hemby SE. Elevated GRIA1 mRNA expression in layer II/III and V pyramidal cells of the DLPFC in schizophrenia. Schizophr Res. 2007; 97(1-3):277-288.

Hemby SE. Assessment of genome and proteome profiles in cocaine abuse. Prog Brain Res. 2006; 158():173-195.

O'Connor JA, Hasenkamp W, Horman BM, Muly EC, Hemby SE. Region specific regulation of NR1 in rhesus monkeys following chronic antipsychotic drug administration. Biol Psychiatry. 2006; 60(6):659-662.

Tannu NS, Hemby SE. Methods for proteomics in neuroscience. Prog Brain Res. 2006; 158():41-82.

Hemby S. Mechanisms of transcriptional regulation in the alcoholic brain [abstract]. Alcohol Clin Exp Res. 2006; 30(9 Suppl):76A.

Hemby S. Ethanol self-administration and the regulation of GABAA alpha subunit mRNAs in frontal corticol areas of cynomolgous monkeys [abstract]. Alcohol Clin Exp Res. 2006; 30(9 Suppl):98A.

Hemby SE, O'Connor JA, Acosta G, Floyd D, Anderson N, McCool BA, Friedman D, Grant KA. Ethanol-induced regulation of GABA subunit mRNAs in prefrontal fields of cynomolgus monkeys. Alcohol Clin Exp Res. 2006; 30(12):1978-1985.

Hemby SE, Tannu N, Mash DC, Howell LL. Quantitative proteomic profiling of cocaine's effects in the primate brain [abstract]. Neuropsychopharmacology. 2006; 31(Suppl):S205.

Tannu NS, Hemby SE. Two-dimensional fluorescence difference gel electrophoresis for comparative proteomics profiling. Nat Protoc. 2006; 1(4):1732-1742.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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Last Updated 3/23/2012
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