Profile

Kevin P. High, M.D.Wake Forest Baptist Health

Doctor Rating

4.8 out of 5

14 Ratings

Kevin P. High, M.D.

Program Director,
Chair, Internal Medicine
Section Chief,
Professor,







Clinical Specialties

Infectious Diseases, Immune Compromise, Transplantation

Contact Information

Department: 336-716-4395

Insurance Accepted »

Media Medical Expert »

Education & Training

  • B.S., Bucknell University , 1982
  • M.D., University of Virginia School of Medicine , 1986
  • Internship, Internal Medicine, Univ Of Virginia Hospitals, 1987
  • Residency, Internal Medicine, Univ Of Virginia Hospitals, 1990
  • Fellowship, Yale University School of Medi, 1993

Memberships

  • Am Coll Of Physicians
  • Infectious Disease Society Of

NPI Number

  • 1144205428
Kevin P. High, M.D.

Doctor Rating

4.8 out of 5

14 Ratings

Kevin P. High, M.D.

Program Director, Translational Science Institute
Chair, Internal Medicine
Section Chief, Infectious Diseases
Professor, Infectious Diseases
Translational Science Institute
Comprehensive Cancer Center
Sticht Center on Aging
WFU Primate Center
Institute for Regenerative Medicine

Research Interests

aging, aids, cancer/oncogenesis, cross(mult/tnslat/inter)discip, fitness/physical, health services, research/outc, immunology/allergy/inflammatio, infectious diseases, prevention, vaccines, women's health issues

Contact Information

Academic: 336-716-4584 | Department: 336-716-4395

Media Medical Expert »

Recent Publications



Freedman BI, Divers J, High KP. The authors reply [to editorial comment on 'JC polyoma virus and kidney disease'] [letter]. Kidney Int. 2014;85(5):1242-1243.

Uhlig K, Leff B, Kent D, Dy S, Brunnhuber K, Burgers JS, Greenfield S, Guyatt G, High K, Leipzig R, Mulrow C, Schmader K, Schunemann H, Walter LC, Woodcock J, Boyd CM. A framework for crafting clinical practice guidelines that are relevant to the care and management of people with multimorbidity. J Gen Intern Med. 2014;29(4):670-679.

Strowd RE, Swett K, Harmon M, Carter AF, Pop-Vicas A, Chan M, Tatter SB, Ellis T [deceased], Blevins M, High K, Lesser GJ. Influenza vaccine immunogenicity in patients with primary central nervous system malignancy. Neuro Oncol. 2014;():.

Khan T, Heffron CL, High KP, Roberts PC. Tailored vaccines targeting the elderly using whole inactivated influenza vaccines bearing cytokine immunomodulators. J Interferon Cytokine Res. 2014;34(2):129-139.



Halter JB, Musi N, McFarland Horne F, Crandall JP, Goldberg A, Harkless L, Hazzard WR, Huang ES, Kirkman MS, Plutzky J, Schmader KE, Zieman S, High KP. Diabetes and cardiovascular disease in older adults: current status and future directions. Diabetes. 2014;63(8):2578-2589.

Choi SJ, Shively CA, Register TC, Feng X, Stehle J, High K, Ip E, Kritchevsky SB, Nicklas B, Delbono O. Force-generation capacity of single vastus lateralis muscle fibers and physical function decline with age in African green vervet monkeys.. J Gerontol A Biol Sci Med Sci. 2013;68(3):258-267.

Louie TJ, Miller MA, Crook DW, Lentnek A, Bernard L, High KP, Shue YK, Gorbach SL. Effect of age on treatment outcomes in Clostridium difficile infection. J Am Geriatr Soc. 2013;61(2):222-230.

Oppenheimer AP, Koh C, McLaughlin M, Williamson JC, Norton TD, Laudadio J, Heller T, Kleiner DE, High KP, Morse CG. Vanishing bile duct syndrome in human immunodeficiency virus infected adults: a report of two cases. World J Gastroenterol. 2013;19(1):115-121.

Wang JM, Ma CJ, Li GY, Wu XY, Thayer P, Greer P, Smith AM, High KP, Moorman JP, Yao ZQ. Tim-3 alters the balance of IL-12/IL-23 and drives TH17 cells: role in hepatitis B vaccine failure during hepatitis C infection. Vaccine. 2013;31(18):2238-2245.

Moorman J, Wang JM, Ma CJ, Wu X, Thayer P, Greer P, McIntyre A, High K, Yao ZQ. Tim-3 alters Il12/Il23 balance and drives T-H 17 cells; role in hepatitis B vaccine failure during hepatitis C infection [abstract]. J Hepatol. 2013;58(Suppl 1):S196.

Plate JF, Bates CM, Mannava S, Smith TL, Jorgensen MJ, Register TC, Stehle JR, High KP, Shively CA, Kaplan JR, Saul KR, Tuohy CJ. Age-related degenerative functional, radiographic, and histological changes of the shoulder in nonhuman primates. J Shoulder Elbow Surg. 2013;22(8):1019-1029.

Divers J, Nunez M, High KP, Murea M, Rocco MV, Ma L, Bowden DW, Hicks PJ, Spainhour M, Ornelles DA, Kleiboeker SB, Duncan K, Langefeld CD, Turner J, Freedman BI. JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy. Kidney Int. 2013;84(6):1207-1213.

Friedman H, Navaratnam P, Reardon G, High DP, Strauss M. Clostridium difficile-associated disease recurrence in US long term care facilities [abstract]. J Am Geriatr Soc. 2012;60(Suppl 4):S228-S229.

Friedman H, Navaratnam P, Reardon G, High KP, Strauss M. Characteristics and outcomes related to clostridium difficile-associated disease in US long term care facilities [abstract]. J Am Geriatr Soc. 2012;60(Suppl 4):S229.

Abrass CK, Appelbaum JS, Boyd CM, Braithwaite R, Broudy VC, Covinsky K, Crothers KA, Harrington R, Drootin M, Gebo K, Goodkin K, Havlik RJ, Hazzard W, High K, Hsue P, John MD, Justice A, Karpiak S, McCormick WC,. Summary report from the Human Immunodeficiency Virus and Aging Consensus Project: treatment strategies for clinicians managing older individuals with the human immunodeficiency virus. J Am Geriatr Soc. 2012;60(5):974-979.

High KP, Case D, Hurd D, Powell B, Lesser G, Falsey AR, Siegel R, Metzner-Sadurski J, Krauss JC, Chinnasami B, Sanders G, Rousey S, Shaw EG. A randomized, controlled trial of Panax quinquefolius extract (CVT-E002) to reduce respiratory infection in patients with chronic lymphocytic leukemia. J Support Oncol. 2012;10(5):195-201.

High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, Deren S, Effros RB, Gebo K, Goronzy JJ, Justice AC, Landay A, Levin J, Miotti PG, Munk RJ, Nass H, Rinaldo CR Jr, Shlipak MG, Tracy R, Valcour V, Vance DE, Walston JD, Volberding P. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defic Syndr. 2012;60(1):S1-S18.

Freedman BI, Langefeld CD, Turner J, Nunez M, High KP, Spainhour M, Hicks PJ, Bowden DW, Reeves-Daniel AM, Murea M, Rocco MV, Divers J. Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease. Kidney Int. 2012;82(7):805-811.

Abecassis M, Bridges ND, Clancy CJ, Dew MA, Eldadah B, Englesbe MJ, Flessner MF, Frank JC, Friedewald J, Gill J, Gries C, Halter JB, Hartmann EL, Hazzard WR, Horne FM, Hosenpud J, Jacobson P, Kasiske BL, Lake J,. Solid-organ transplantation in older adults: current status and future research. Am J Transplant. 2012;12(10):2608-2622.

High KP, Akbar AN, Nikolich-Zugich J. Translational research in immune senescence: assessing the relevance of current models. Semin Immunol. 2012;24(5):373-382.

Stehle JR Jr, Leng X, Kitzman DW, Nicklas BJ, Kritchevsky SB, High KP. Lipopolysaccharide-binding protein, a surrogate marker of microbial translocation, is associated with physical function in healthy older adults. J Gerontol A Biol Sci Med Sci. 2012;67(11):1212-1218.

Strowd RE, Swett K, Harmon M, Pop-Vicas A, Chan M, Tatter SB, Ellis TL [deceased], Blevins M, High K, Lesser GJ. A pilot study of influenza vaccine immunogenicity in patients with malignant central nervous system (CNS) tumors [abstract]. Neuro Oncol. 2012;14(Suppl 6):154.

Anderson S, Eldadah B, Halter JB, Hazzard WR, Himmelfarb J, Horne FM, Kimmel PL, Molitoris BA, Murthy M, High KP, et al. Acute kidney injury in older adults. J Am Soc Nephrol. 2011;22(1):28-38.

Louie T, Miller M, Crook D, Lentnek A, Bernard L, High K, Shue YK, Gorbach S. Effect of advancing age on outcomes of therapy for clostridium difficile infection [abstract]. J Am Geriatr Soc. 2011;59(Suppl 1):S106-S107.

Watkins FS, Williamson JD, High KP, Podrazik PM, Atkinson HH. Impact of a geriatrics-based faculty development program for subspecialists in internal medicine [abstract]. J Am Geriatr Soc. 2011;59(Suppl 1):S82.

Shores N, Mendes-Correa MC, Maida I, Turner J, Uip DE, High K, Nunez M. Hepatic PPAR gamma expression is further impaired in HCV-infected subjects with HIV-co-infection [abstract]. Hepatology. 2011;54(Suppl 1):1331A.

Stehle JR, Nicklas B, Kritchevsky SB, Kitzman DW, Leng X, High K. Association between microbial translocation and adiposity in healthy elderly adults [abstract]. Gerontologist. 2011;51(Suppl 2):490.

Morse CG, High KP. Nutrition, immunity, and infection In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett's principles and practice of infectious diseases, vol 1. 7th ed. Philadelphia: Churchill Livingstone/Elsevier;2010: 151-159.

High KP, D'Aquila RT, Fuldner RA, Gerding DN, Halter JB, Haynes L, Hazzard WR, Jackson LA, Janoff E, Woolard NF, et al. Workshop on immunizations in older adults: identifying future research agendas. J Am Geriatr Soc. 2010;58(4):765-776.

High KP, Case LD, Siegel RD, Metzner-Sidurski J, Krauss JC, Chinnasami B, Sanders GH, Rousey S, Lesser GJ, Shaw EG. A phase III randomized, double-blind, placebo controlled trial of North American (NA) ginseng (Panax quinquefolium) extract (CVT-E002) in patients with chronic lymphocytic leukemia: effect on respiratory infection and antibiotic use [abstract]. J Clin Oncol. 2010;28(15 Suppl):6578.

Atkinson HH, Watkins FS, High KP, Lawlor JS, Lambros A, Williamson JD. Comparison of trainee, peer, and self ratings of geriatrics teaching: a videotaped observed teaching exercise [abstract]. J Am Geriatr Soc. 2010;58(Suppl 1):39-40.

Castriotta RJ, Eldadah BA, Foster WM, Halter JB, Hazzard WR, Kiley JP, King TE Jr, Horne FM, Nayfield SG, High KP, et al. Workshop on idiopathic pulmonary fibrosis in older adults. Chest. 2010;138(3):693-703.

Myer RG, El Mezayen R, High KP. Prostaglandin E2-dependent IL-23 production in aged murine dendritic cells. Exp Gerontol. 2010;45(11):834-841.

High KP, Bradley SF, Gravenstein S, Mehr DR, Quagliarello VJ, Richards C, Yoshikawa TT. Clinical practice guideline for the evaluation of fever and infection in older adult residents of long-term care facilities: 2008 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009;48(2):149-171.

High KP, Bradley SF, Gravenstein S, Mehr DR, Quagliarello VJ, Richards C, Yoshikawa TT. Clinical practice guideline for the evaluation of fever and infection in older adult residents of long-term care facilities: 2008 update by the Infectious Diseases Society of America. J Am Geriatr Soc. 2009;57(3):375-394.

High KP. Infection in the elderly In: Halter JB, Ouslander JG, Tinetti ME, Studenski S, High KP, Asthana S, Hazzard WR, Wollard NF, eds. Hazzard's geriatric medicine and gerontology. 6th ed. New York: McGraw Hill Medical;2009: 1507-1515.

Halter JB, Ouslander JG, Tinetti ME, Studenski S, High KP, Asthana S, Hazzard WR, Wollard NF. In: Hazzard's geriatric medicine and gerontology. 6th ed. New York: McGraw Hill Medical;2009: .

Anderson S, Halter JB, Hazzard WR, Himmelfarb J, Horne FM, Kaysen GA, Kusek JW, Nayfield SG, Schmader K, High KP, et al. Prediction, progression, and outcomes of chronic kidney disease in older adults. J Am Soc Nephrol. 2009;20(6):1199-1209.

High KP. Overcoming barriers to adult immunization. J Am Osteopath Assoc. 2009;109(6 Suppl 2):S25-S28.


High KP, Yoshikawa TT. Reply to Dr. Snustad [reply to letter]. J Am Geriatr Soc. 2009;57(11):2158-2159.

Nunez M, Beltz A, High K. Effect of HIV on levels of serum markers of liver inflammation and fibrosis in hepatitis C virus co-infection [abstract]. Hepatology. 2009;50(4 Suppl):923A-924A.

High KP. Nutrition and infection In: Yoshikawa TT, Norman DC, eds. Infectious disease in the aging: a clinical handbook. 2nd ed. Totowa (NJ): Humana Press;2009: 455-466.

Norris SL, High K, Gill TM, Hennessy S, Kutner JS, Reuben DB, Unutzer J, Landefeld CS. Health care for older Americans with multiple chronic conditions: a research agenda. J Am Geriatr Soc. 2008;56(1):149-159.

Effros RB, Fletcher CV, Gebo K, Halter JB, Hazzard WR, Horne FM, Huebner RE, Janoff EN, Woolard NF, High KP, et al. Workshop on HIV infection and aging: what is known and future research directions. Clin Infect Dis. 2008;47(4):542-553.

Kennedy LD, Gatesman ML, High K, Karchmer TB. An evaluation of infections and resistance patterns after implementation of antibiotic prophylaxis in neutropenic cancer patients [abstract]. Biol Blood Marrow Transplant. 2007;13(2 Suppl 2):75-76.


High KP. Nutrition and infection In: Yoshikawa TT, Ouslander JG, eds. Infection management for geriatrics in long-term care facilities. 2nd ed. New York: Informa Healthcare;2007: 71-86.

High K. Immunizations in older adults. Clin Geriatr Med. 2007;23(3):669-685.

High K. Preface. Clin Geriatr Med. 2007;23(3):xi-xii.

High KP, Prasad R, Marion CR, Schurig GG, Boyle SM, Sriranganathan N. Outcome and immune responses after Brucella abortus infection in young adult and aged mice. Biogerontology. 2007;8(5):583-593.

Goodrum F, Reeves M, Sinclair J, High K, Shenk T. Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro. Blood. 2007;110(3):937-945.

High KP. Preventing herpes zoster and postherpetic neuralgia through vaccination. J Fam Pract. 2007;56(10 Suppl A):51A-58A.

van Burik JH, Carter SL, Freifeld AG, High KP, Godder KT, Papanicolaou GA, Mendizabal AM, Wagner JE, Yanovich S, Kernan NA. Higher risk of cytomegalovirus and aspergillus infections in recipients of T cell-depleted unrelated bone marrow:. Biol Blood Marrow Transplant. 2007;13(12):1487-1498.

Monjazeb AM, High KP, Connoy A, Hart LS, Koumenis C, Chilton FH. Arachidonic acid-induced gene expression in colon cancer cells. Carcinogenesis. 2006;27(10):1950-1960.


Hickman CL, High KP, Wells JD, Mizel SB. Serum modulation of flagellin-induced human dendritic cell maturation [abstract]. J Immunol. 2006;176(Suppl):S64.

Sonu IS, High KP, Clayton CP, Woolard NF, Hazzard WR. An evaluation of geriatrics activities within internal medicine subspecialties. Am J Med. 2006;119(11):995-1000.

High KP. Murine models of infectious diseases in the aged In: Conn PM, ed. Handbook of models for human aging. Amsterdam: Elsevier Academic Press;2006: 651-660.

High KP. Assessment of nutritional status and interventions to reduce infection risk in the elderly In: Yoshikawa TT, Rajagopalan S, eds. Antibiotic therapy for geriatric patients. Boca Raton (FL): Taylor & Francis;2006: 53-66.

High KP. Infectious diseases In: Pompei P, Murphy JB, eds. Geriatrics review syllabus: a core curriculum in geriatric medicine. 6th ed. New York: American Geriatrics Society;2006: 332-343.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Infectious Diseases
Translational Science Institute

Clinical Specialties

Infectious Diseases, Immune Compromise, Transplantation
Kevin P. High, M.D.

Kevin P. High, M.D.

Program Director, Translational Science Institute
Chair, Internal Medicine
Section Chief, Infectious Diseases
Professor, Infectious Diseases
Translational Science Institute
Comprehensive Cancer Center
Sticht Center on Aging
WFU Primate Center
Institute for Regenerative Medicine

Doctor Rating

4.8 out of 5

Kevin P. High, M.D.14 Ratings

Doctor Ratings

The overall Patient Rating score is the average of responses to the nine questions listed below. The questions are from the Press Ganey Patient Satisfaction Survey. Responses are measured on a 1 to 5 scale, where 1 represents "very poor" and 5 represents "very good."
Press Ganey Patient Satisfaction Survey

CP concern for questions/worries
4.9
CP efforts to include in decisions
4.9
CP explanations of prob/condition
4.7
CP spoke using clear language
4.8
Friendliness/courtesy of CP
5
Likelihood of recommending CP
5
Patients' confidence in CP
5
Time CP spent with patient
4.8
Wait time at clinic
4.2

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