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William H. Hinson, Ph.D.Wake Forest School of Medicine

William H. Hinson, Ph.D.

Associate Professor,

Clinical Interests

Radiation Oncology Physics, Magnetic Resonance Imaging, Stereotactic Body Radiation Therapy, Stereotactic Radiosurgery

Contact Information

Academic: 336-713-6521 | Department: 336-713-3600

Email: whinson@wakehealth.edu

Education & Training

  • B.A., Wake Forest University, 1983
  • M.S., Wake Forest University, 1985
  • Ph.D., Wake Forest University, 1999

Memberships

  • Am Assn Of Physicists In Med
  • Am Soc Ther Rad & Rad Oncology
William H. Hinson, Ph.D.

William H. Hinson, Ph.D.

Associate Professor, Radiation Oncology

Research Interests

Particle Accelerators; Radiosurgery; Algorithms; Radiotherapy Planning, Computer-Assisted; Radiation Protection
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Contact Information

Academic: 336-713-6521 | Department: 336-713-3600

Email: whinson@wakehealth.edu

Recent Publications

Reirradiation for second primary or recurrent cancers of the head and neck: dosimetric and outcome analysis. Garg S, Kilburn JM, Lucas JT Jr, Randolph D, Urbanic JJ, Hinson WH, Kearns WT, Porosnicu M, Greven K.. Head Neck. 2016;38(Suppl 1):E961-E969.

Image guided radiation therapy may result in improved local control in locally advanced lung cancer patients. Kilburn JM, Soike MH, Lucas JT, Ayala-Peacock D, Blackstock W, Isom S, Kearns WT, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.. Pract Radiat Oncol. 2016;6(3):e73-e80.

Emerging indications for fractionated gamma knife radiosurgery. McTyre E, Helis CA, Farris M, Wilkins L, Sloan D, Hinson WH, Bourland JD, Dezarn WA, Munley MT, Watabe K, Xing F, Laxton AW, Tatter SB, Chan MD.. Neurosurgery. 2016;():.

Is a clinical target volume (CTV) necessary in the treatment of lung cancer in the modern era combining 4-D imaging and image-guided radiotherapy (IGRT)?. Kilburn JM, Lucas JT, Soike MH, Ayala-Peacock DN, Blackstock AW, Hinson WH, Munley MT, Petty WJ, Urbanic JJ.. Cureus. 2016;8(1):e466.

Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases. Johnson AG, Ruiz J, Hughes R, Page BR, Isom S, Lucas JT, McTyre ER, Houseknecht KW, Ayala-Peacock DN, Bourland DJ, Hinson WH, Laxton AW, Tatter SB, Debinski W, Watabe K, Chan MD.. Oncotarget. 2015;6(22):18945-55.

Genomic predictors of patterns of progression in glioblastoma and possible influences on radiation field design. Holmes JA, Paulsson AK, Page BR, Miller LD, Liu W, Xu J, Hinson WH, Lesser GJ, Laxton AW, Tatter SB, Debinski W, Chan MD.. J Neurooncol. 2015;124(3):447-453.

A multi-institutional analysis of patients treated with stereotactic radiosurgery for brain metastases from radioresistant histologies [abstract]. Smith CA, McTyre E, Isom S, Kennedy VE, Luo G, Morales-Paliza M, Hinson W, Cmelak AJ, Tatter SB, Chan MD, Attia A.. Int J Radiat Oncol Biol Phys. 2015;93(3):E87-E88.

A competing risks analysis assessing predictors of neurologic and non-neurologic death in patients with brain metastasis initially treated with upfront stereotactic radiosurgery without whole-brain radiation therapy [abstract]. McTyre E, Johnson A, Ruiz J, Isom S, Lucas JT Jr, Hinson W, Watabe K, Laxton AW, Tatter SB, Chan MD.. Int J Radiat Oncol Biol Phys. 2015;93(3 Suppl):S176.

Impact of socioeconomic status on brain metastasis outcomes at a large academic radiosurgery center [abstract]. Houseknecht K, Taksler GB, Johnson A, Page BR, Hinson W, Laxton AW, Tatter SB, Weaver KE, Chan MD, Ruiz J.. Int J Radiat Oncol Biol Phys. 2015;93(3 Suppl):E366.

Management of mediastinal relapse after treatment with stereotactic body radiotherapy or accelerated hypofractionated radiotherapy for stage I/II non-small-cell lung cancer. Kilburn JM, Lester SC, Lucas JT Jr, Soike MH, Blackstock AW, Kearns WT, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.. J Thorac Oncol. 2014;9(4):572-576.

Thoracic re-irradiation using stereotactic body radiotherapy (SBRT) techniques as first or second course of treatment. Kilburn JM, Kuremsky JG, Blackstock AW, Munley MT, Kearns WT, Hinson WH, Lovato JF, Miller AA, Petty WJ, Urbanic JJ.. Radiother Oncol. 2014;110(3):505-510.

Limited margins using modern radiotherapy techniques does not increase marginal failure rate of glioblastoma. Paulsson AK, McMullen KP, Peiffer AM, Hinson WH, Kearns WT, Johnson AJ, Lesser GJ, Ellis TL, Tatter SB, Debinski W, Shaw EG, Chan MD.. Am J Clin Oncol. 2014;37(2):177-181.

Taste and smell disturbances after brain irradiation: a dose-volume histogram analysis of a prospective observational study. Leyrer CM, Chan MD, Peiffer AM, Horne E, Harmon M, Carter AF, Hinson WH, Mirlohi S, Duncan SE, Dietrich AM, Lesser GJ.. Pract Radiat Oncol. 2014;4(2):130-135.

Comparison of clinical outcomes and genomic characteristics of single focus and multifocal glioblastoma. Paulsson AK, Holmes JA, Peiffer AM, Miller LD, Liu W, Xu J, Hinson WH, Lesser GJ, Laxton AW, Tatter SB, Debinski W, Chan MD.. J Neurooncol. 2014;119(2):429-435.

Which lung tumors shrink during fractionated radiation and how does this influence outcome?: Appropriately selecting tumor and treatment characteristics for adaptive radiation therapy protocols [abstract]. Kilburn JM, Lucas JT, Soike MH, Ayala-Peacock D, Kuremsy JG, Blackstock A, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S641-S642.

An evaluation of toxicity using accumulated total dose based on EQD2 for thoracic reirradiation incorporating at least 1 course of SBRT [abstract]. Lester SC, Kilburn JM, Lucas JT, Soike MH, Blackstock AW, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S640-S641.

Does delay of start of radiation affect clinical outcomes of glioblastoma [abstract]. Randolph DM, Peiffer AM, Paulsson AK, Hinson W, Laxton AW, Tatter SB, Debinski W, Chan MD.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S295.

Genomic predictors of infield and marginal failure for glioblastoma treated with concurrent radiation therapy and temozolomide: a step towards personalized radiation fields? [abstract]. Holmes JA, Paulsson A, Peiffer AM, Miller LD, Xu J, Hinson WH, Lesser GJ, Tatter SB, Debinski W, Chan MD.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S291-S292.

Neuroanatomical target theory as a predictive model for radiation-induced cognitive decline. Peiffer AM, Leyrer CM, Greene-Schloesser DM, Shing E, Kearns WT, Hinson WH, Tatter SB, Ip EH, Rapp SR, Robbins ME [deceased], Shaw EG, Chan MD.. Neurology. 2013;80(8):747-753.

Stereotactic body radiation therapy (SBRT) and image guided accelerated hypofractionated radiation therapy (IGAHRT) for the treatment of oligometastatic cancers [abstract]. Ayala-Peacock DN, Blackstock AW, Kearns WT, Hinson WH, Munley MT, Miller AA, Petty WJ, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S567-S568.

Re-irradiation for second primary or recurrent cancers of the head and neck: composite dosimetric measures to evaluate dose to the carotid arteries [abstract]. Garg S, Kilburn JM, Randolph DM, Lucas JT, Urbanic JJ, Porosnicu M, Hinson WH, Kearns WT, Greven KM.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S480-S481.

Is a clinical target volume (CTV) necessary in treatment of thoracic malignancies treated in the modern era combining 4-D imaging and image guided radiation therapy (IGRT)? [abstract]. Kilburn JM, Lucas JT, Soike MH, Ayala-Peacock D, Blackstock AW, Kearns WT, Hinson WH, Miller AA, Petty WJ, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S549.

Multiple courses of thoracic radiation therapy (XRT) using stereotactic body radiation therapy (SBRT) as the first or second course of treatment for tumors outside the original high-dose region [abstract]. Kilburn JM, Lester SC, Lucas JT, Blackstock AW, Kearns WT, Hinson WH, Munley MT, Miller AA, Petty WJ, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S36.

Salvage radiation for mediastinal relapse after treatment with accelerated hypofractionated radiation therapy (AHRT) or stereotactic body radiation therapy (SBRT) for stage I/II NSCLC [abstract]. Lester SC, Kilburn JM, Lucas JT, Munley MT, Blackstock AW, Kearns WT, Hinson WH, Miller AA, Petty WJ, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S543-S544.

Image guided radiation therapy results in mproved local control in lung cancer patients treated with fractionated radiation therapy for stage IIB-IIIB disease [abstract]. Soike M, Kilburn JM, Lucas JT, Ayala-Peacock D, Blackstock AW, Kearns WT, Hinson WH, Miller AT [sic] [Miller AA], Petty WJ, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S547-S548.

Normal tissue complication probability (Ntcp) model of radiation-induced mood disruption [abstract]. Peiffer AM, Burke A, Leyer CM, Shing E, Kearns WT, Hinson WH, Case D, Rapp SR, Shaw EG, Chan MD.. Neuro Oncol. 2013;15(Suppl 3):230.

Thoracic reirradiation in patients with stereotactic body radiation therapy (SBRT) as first or second course of treatment [abstract]. Kilburn JM, Kuremsky JG, Blackstock AW, Kearns WT, Hampton CJ, Hinson WH, Miller AA, Petty WJ, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S604.

Hypofractionated radiation therapy for stage I and II non-small cell lung cancer [abstract]. Kuremsky JG, Petty WJ, Miller A, Hinson WH, Hampton CJ, Blackstock AW, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S153-S154.

Radiation-induced taste and smell toxicity: a dose-volume histogram analysis of a prospective observational study [abstract]. Leyrer M, Chan MD, Peiffer AM, Horne E, Harmon M, Carter AF, Hinson WH, Duncan SE, Dietrich AM, Lesser GJ.. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S302.

Comparison of clinical outcomes for single focus and multifocal glioblastoma [abstract]. Paulsson A, Peiffer AM, McMullen KP, Hinson WH, Lesser GJ, Ellis TL [deceased], Tatter SB, Shaw EG, Chan MD.. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S274.

Long-term follow-up and patterns of failure for patients with medically inoperable stage I non-small cell lung cancer (NSCLC) treated with stereotactic body radiation therapy (SBRT) [abstract]. Urbanic JJ, Soike M, Hampton CJ, Lucas J, Hinson W, Kearns W, Blackstock AW.. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S609.

Thoracic re-irradiation in patients with stereotactic body radiotherapy (SBRT) as first or second course of treatment [abstract]. Kilburn KM, Kuremsky JG, Blackstock AW, Kearns WT, Hampton CJ, Hinson WH, Miller AA, Petty WJ, Urbanic JJ.. J Thorac Oncol. 2012;7(9 Suppl 4):S253-S254.

Hypofractionated radiotherapy for stage I and II non-small cell lung cancer [abstract]. Kuremsky JG, Petty WJ, Miller A, HInson WH, Hampton CJ, Blackstock AW, Urbanic JJ.. J Thorac Oncol. 2012;7(9 Suppl 4):S230.

Comparison of accelerated hypofractionation and stereotactic body radiotherapy for stage 1 & 2 non-small cell lung cancer (NSCLC) [abstract]. Lucas JT, Kuremsky JG, Soike M, Hinson W, Kearns WT, Hampton CJ, Blackstock AW, Urbanic JJ.. J Thorac Oncol. 2012;7(9 Suppl 4):S228.

Long-term follow-up and patterns of failure for patients with medically inoperable Stage I non-small cell lung cancer (NSCLC) treated with stereotactic body radiotherapy (SBRT) [abstract]. Urbanic JJ, Soike M, Hampton CJ, Lucas J, Hinson W, Kearns W, Blackstock AW.. J Thorac Oncol. 2012;7(9 suppl 4):S288.

Normal tissue complication modeling of the brain: dose-volume histogram analysis of neurocognitive outcomes of two CCOP trials [abstract]. Leyrer CM, Peiffer AM, Greene-Schloesser DM, Kearns WT, Hinson WH, Tatter SB, Rapp SR, Robbins ME, Shaw EG, Chan MD.. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S184-S185.

Decreased CTV margin size does not affect patterns of failure for glioblastoma treated with concurrent radiotherapy and temozolomide [abstract]. Paulsson AK, Chan MD, Peiffer AM, Hinson WH, Kearns WT, Lesser GJ, Ellis TL, Tatter SB, Shaw EG, McMullen KP.. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S183.

Normal tissue complication modeling of the brain: dose-volume histogram analysis of neurocognitive outcomes of two CCOP trials [abstract]. Peiffer AM, Leyrer CM, Greene-Schloesser D, Kearns WT, Hinson WH, Tatter SB, Rapp SR, Robbins ME, Shaw EG, Chan MD.. Neuro Oncol. 2011;13(Suppl 3):73.

A phase I study of gefitinib with concurrent dose-escalated weekly docetaxel and conformal three-dimensional thoracic radiation followed by consolidative docetaxel and maintenance gefitinib for patients with stage III non-small cell lung cancer. Center B, Petty WJ, Ayala D, Hinson WH, Lovato J, Capellari J [sic] [Cappellari J], Oaks T, Miller AA, Blackstock AW.. J Thorac Oncol. 2010;5(1):69-74.

Stereotactic body radiation therapy: the report of AAPM Task Group 101. Benedict SH, Yenice KM, Followill D, Galvin JM, Hinson W, Kavanagh B, Keall P, Lovelock M, Meeks S, Papiez L, et al.. Med Phys. 2010;37(8):4078-4101.

Photon spectral characteristics of dissimilar 6 MV linear accelerators. Hinson WH, Kearns WT, deGuzman AF, Bourland JD.. Med Phys. 2008;35(5):1698-1702.

Anniversary paper: the role of medical physicists in developing stereotactic radiosurgery. Benedict SH, Bova FJ, Clark B, Goetsch SJ, Hinson WH, Leavitt DD, Schlesinger DJ, Yenice KM.. Med Phys. 2008;35(9):4262-4277.

Impact of individualized target volumes on stereotactic body radiotherapy treatment planning (SBRT): volumetric analysis [abstract]. Hampton CJ, Kearns WT, Urbanic JJ, McMullen KP, Blackstock AW, Hinson WH.. Int J Radiat Oncol Biol Phys. 2008;72(1 Suppl):S617.

Impact of individualized target volumes on stereotactic body radiotherapy treatment planning (SBRT): dosimetric analysis [abstract]. Hampton CJ, Kearns WT, Urbanic JJ, McMullen KP, Blackstock AW, Hinson WH.. Int J Radiat Oncol Biol Phys. 2008;72(1 Suppl):S625-S626.

Radiation safety issues with positron-emission/computed tomography simulation for stereotactic body radiation therapy. Kearns WT, Urbanic JJ, Hampton CJ, McMullen KP, Blackstock AW, Stieber VW, Hinson WH.. J Appl Clin Med Phys. 2008;9(3):141-146.

A phase I/II dose-escalation/efficacy study, of single fraction stereotactic body radiotherapy (SF-SBRT) for metastatic cancer [abstract]. Urbanic JJ, McMullen KP, Stieber VW, Hinson WH, Kearns WT, Hampton CJ, Lovato JF, Livengood K, Rosdahl R, Blackstock AW.. Int J Radiat Oncol Biol Phys. 2008;72(1 Suppl):S140.

Optically guided linac radiosurgery with a Leksell head frame as an adjunct to gamma knife treatment. Ekstrand KE, Hinson WH, Kearns W, Bourland JD, deGuzman AF, McMullen KP, Stieber VW.. Technol Cancer Res Treat. 2007;6(2):123-126.

Reducing set-up uncertainty in the Elekta Stereotactic Body Frame using Stealthstation software. Hinson WH, Kearns WT, Ellis TL, Sprinkle D, Cullen T, Smith PG, Stieber VW.. Technol Cancer Res Treat. 2007;6(3):181-186.

Light-radiation field coincidence for small stereotactic fields [abstract]. Ekstrand K, Munley M, Kearns W, Hinson W, deGuzman A.. Med Phys. 2007;34(6):2466.

New tools and methodology for stereotactic body radiotherapy (SBRT) simulation using 4DCT [abstract]. Hampton CJ, Kearns WT, Hinson WH.. Med Phys. 2007;34(6):2474.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Radiation Oncology

Clinical Interests

Radiation Oncology Physics, Magnetic Resonance Imaging, Stereotactic Body Radiation Therapy, Stereotactic Radiosurgery
William H. Hinson, Ph.D.

William H. Hinson, Ph.D.

Associate Professor, Radiation Oncology

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