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Research

Robert D. Hite, M.D.

Professor, Pulmonary, Critical Care, Allergy, and Immunologic Medicine

Clinical Specialties

General Pulmonary Diseases, Quality of Life, Pulmonary Hypertension, Acute Respiratory Distress Syndrome (ARDS), Sepsis, Surfactant Deficiencies, Quality Improvement, Critical Care

Contact Information

Department: 336-716-2011

Insurance Accepted »

Education & Training

M.D., University of Texas Medical School-Houston , 1986
B.S., Southern Methodist University , 1982
Internship, Internal Medicine, Univ Of Virginia Hospitals, 1987
Residency, Internal Medicine, Univ Of Virginia Hospitals, 1989
Fellowship, University of California-San Diego, 1993
Fellowship, Scripps Memorial Hosp, 1994

Memberships

Soc Of Critical Care Medicine
Amer Coll Of Chest Physicians
Am Coll Of Physicians
Am Federation Of Clinical Rese
Am Lung Assn
American Thoracic Society
European Respiratory Society

NPI Number

1346225760

Robert D. Hite, M.D.

Professor, Pulmonary, Critical Care, Allergy, and Immunologic Medicine

Research Interests

critical/intensive care medici, drugs/therapeutic agents pharm, immunology/allergy/inflammatio

Contact Information

Academic: 336-716-8898 | Department: 336-716-2011

Recent Publications

Files DC, Hite RD. Predicting acute lung injury resolution: a role for chest CT? [editorial]. Crit Care Med. 2013;41(2):668-669.

Metersky ML, Hite RD. Increasing incidence of prolonged acute mechanical ventilation: can we bend the utilization curve? [editorial]. Crit Care Med. 2012;40(1):298-299.

Hite RD, Grier BL, Waite BM, Veldhuizen RA, Possmayer F, Yao L-J, Seeds MC. Surfactant protein B inhibits secretory phospholipase A2 hydrolysis of surfactant phospholipids. Am J Physiol Lung Cell Mol Physiol. 2012;302(2):L257-265.

Miles M, Hite RD. A randomized controlled trial of direct noise reduction in the ICU [abstract]. J Investig Med. 2012;60(1):455.

Rice TW, Wheeler AP, Thompson BT, Steingrub J, Hite RD, Moss M, Morris A, Dong N, Rock P. Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA. 2012;307(8):795-803.

Calfee CS, Gallagher D, Abbott J, Thompson BT, Matthay MA, Hite RD, Morris P, Howard A, Nesser A, Perez S, et al. Plasma angiopoietin-2 in clinical acute lung injury: prognostic and pathogenetic significance. Crit Care Med. 2012;40(6):1731-1737.

Seeds MC, Grier BL, Suckling BN, Safta AM, Long DL, Waite BM, Morris PE, Hite RD. Secretory phospholipase A2-mediated depletion of phosphatidylglycerol in early acute respiratory distress syndrome. Am J Med Sci. 2012;343(6):446-451.

Miller RR, MacIntyre NR, Hite RD, Truwit JD, Brower RG, Morris AH. Point: should positive end-expiratory pressure in patients with ARDS be set on oxygenation? Yes [editorial]. Chest. 2012;141(6):1379-1382.

Miller RR, MacIntyre NR, Hite RD, Truwit JD, Brower RG, Morris AH. Rebuttal from Dr Miller et al [editorial]. Chest. 2012;141(6):1384-1386.

Blagev DP, Hirshberg EL, Sward K, Thompson BT, Brower R, Truwit J, Hite D, Steingrub J, Orme JF Jr, Clemmer TP, Weaver LK, Thomas F, Grissom CK, Sorenson D, Sittig DF, Wallace CJ, East TD, Warner HR, Morris AH. The evolution of eProtocols that enable reproducible clinical research and care methods. J Clin Monit Comput. 2012;26(4):305-317.

Morris AH, Hirshberg E, Miller RR III, Statler KD, Hite RD. Evidence and experience in extracorporeal membrane oxygenation [reply to letter]. Chest. 2011;139(4):965-966.

Bowton DL, Hite RD. Ventilator mechanics In: Truwit JD, Epstein SK, eds. Practical guide to mechanical ventilation. Chichester (UK): Wiley-Blackwell;2011: 133-139.

Rice TW, Ware LB, Haponik EF, Chiles C, Wheeler AP, Bernard GR, Steingrub JS, Hite RD, Matthay MA, Wright P, et al. Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status. Crit Care. 2011;15(2):R86.

Morris PE, Griffin L, Berry M, Thompson C, Hite RD, Winkelman C, Ross A, Dixon L, Leach S, Haponik E, et al. Receiving early mobility during an intensive care unit admission is a predictor of improved outcomes in acute respiratory failure. Am J Med Sci. 2011;341(5):373-377.

Hite RD. Modes of mechanical ventilation In: Truwit JD, Epstein SK, eds. A practical guide to mechanical ventilation. Chichester (UK): Wiley-Blackwell;2011: 141-162.

Hite RD. Mechanical ventilation in restrictive lung disease In: Truwit JD, Epstein SK, eds. A practical guide to mechanical ventilation. Chichester (UK): Wiley-Blackwell;2011: 173-194.

Matthay MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, MacIntyre N, et al. Randomized, placebo-controlled clinical trial of an aerosolized beta-2 agonist for treatment of acute lung injury. Am J Respir Crit Care Med. 2011;184(5):561-568.

Updaw RJ, Hite R, Blair R, Ireland L, Grier B, Waite M, Seeds M. Cytokine regulation of secretory phospholipases A2 in a differentiated human monocyte cell model [abstract]. Am J Respir Crit Care Med. 2011;183(Meeting Abstracts):A5234.

Hite RD, Seeds MC, Morris PE, Grier BL, Waite BM, Douglas IS, Hudson LD, Goodman RB. Regulation of secretory A2 phospholipase activity in persistent ARDS [abstract]. Am J Respir Crit Care Med. 2010;181():A6474.

Christmann U, Hite RD, Tan RHH, Thatcher CD, Witonsky SG, Werre SR, Buechner-Maxwell VA. Surfactant alterations in horses with recurrent airway obstruction at various clinical stages. Am J Vet Res. 2010;71(4):468-475.

Morris AH, Hirshberg E, Statler KD, Dalton H, Hite RD. Is extracorporeal life support for adults with acute respiratory distress syndrome useful? In: Deutschman CS, Neligan PJ, eds. Evidence-based practice of critical care. Philadelphia: Saunders Elsevier;2010: 141-147.

Morris AH, Hirshberg E, Miller RR III, Statler KD, Hite RD. Counterpoint: Efficacy of extracorporeal membrane oxygenation in 2009 influenza A(H1N1): sufficient evidence? [editorial comment]. Chest. 2010;138(4):778-781.

Morris AH, Hirshberg E, Miller RR III, Statler KD, Hite RD. Rebuttal from Dr Morris et al [editorial]. Chest. 2010;138(4):783-784.

Christmann U, Buechner-Maxwell VA, Witonsky SG, Hite RD. Role of lung surfactant in respiratory disease: current knowledge in large animal medicine. J Vet Intern Med. 2009;23(2):227-242.

Hite RD, Seeds MC, Grier BL, Possmayer F, Veldhuizen RA, Waite BM. Regulation of hydrolysis by secretory phospholipases A2 in surfactant monolayer films [abstract]. Am J Respir Crit Care Med. 2009;179(Online Abstr Issue):A6278.

Christmann U, Hite RD, Witonsky SG, Elvinger F, Werre SR, Thatcher CD, Tan RHH, Buechner-Maxwell VA. Influence of age on surfactant isolated from healthy horses maintained on pasture. J Vet Intern Med. 2009;23(3):612-618.

Lorenz E, Muhlebach MS, Tessier PA, Alexis NE, Hite RD, Seeds MC, Peden DB, Meredith W. Different expression ratio of S100A8/A9 and S100A12 in acute and chronic lung diseases. Respir Med. 2008;102(4):567-573.

Cline J, Foster J, Strong J, Passmore L, King N, Hite R. Medical student perspectives on the role of spirituality in end-of-life decision making [abstract]. J Investig Med. 2008;56(1):442.

Hite RD, Hastie AT, Seeds MC, Grier BL, Peters SP, Moore WC, Bleecker ER. Surfactant alterations in asthmatics from the Wake Forest Severe Asthma Research Program Center [abstract]. Am J Respir Crit Care Med. 2008;177(Abstr Issue):A100.

Blair RA, Hite RD, Seeds MC. Regulation of GP IIA sPLA2 mRNA production in a human monocyte cell model (THP-1) [abstract]. Am J Respir Crit Care Med. 2008;177(Abstr Issue):A750.

Morris PE, Goad A, Thompson C, Taylor K, Harry B, Passmore L, Ross A, Howard A, Hite RD, Haponik E, et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med. 2008;36(8):2238-2243.

Christmann U, Welles EG, Waldridge BM, Schumacher J, Grier BL, Hite RD. Abnormalities in lung surfactant in horses clinically affected with recurrent airway obstruction (RAO). J Vet Intern Med. 2008;22(6):1452-1455.

Rice TW, Wheeler AP, Hite RD, Stapleton RD. Enteral intake and patient characteristics in ventilated acute lung injury (ALI) patients [abstract]. Crit Care Med. 2008;36(12 Suppl):A107.

Christmann U, Buechner-Maxwell V, Witonsky S, Dryman B, Grier B, Hite D. Relationship between lung surfactant alterations and severity of disease in horses with recurrent airway obstruction (RAO) [abstract]. J Vet Intern Med. 2007;21(3):617-618.

Christmann U, Livesey LC, Taintor JS, Waldridge BM, Schumacher J, Grier BL, Hite RD. Lung surfactant function and composition in neonatal foals and adult horses. J Vet Intern Med. 2006;20(6):1402-1407.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

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All

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Pulmonary, Critical Care, Allergy, and Immunologic Medicine

Clinical Specialties

General Pulmonary Diseases, Quality of Life, Pulmonary Hypertension, Acute Respiratory Distress Syndrome (ARDS), Sepsis, Surfactant Deficiencies, Quality Improvement, Critical Care