James Hill Holmes IV, M.D., Associate Professor Surgical Sciences-General Surgery

James Hill Holmes IV, M.D.

Associate Professor, Surgery, General
Institute for Regenerative Medicine

Clinical Specialties

Burns, Trauma and Surgical Critical Care, Emergency General Surgery

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-3813
Department: 336-716-0549

Email: jholmes@wakehealth.edu

Education & Training

B.A., Southern Methodist University , 1990
M.D., U Texas Sthwstn Med Sch-Dallas , 1996
Internship, Virginia Mason Medical Center, 1997
Residency, Virginia Mason Medical Center, 1998
Residency, Virginia Mason Medical Center, 2002
Fellowship, Virginia Mason Rsrch Ctr, 1999
Fellowship, University of Washington School of Medicine, 2003
Fellowship, University of Pennsylvania School of Medicine, 2004

Board Certifications

American Board of Surgery

Memberships

Int'l Soc of Burn Injuries
North Carolina Medical Society
Southern Medical Association
Texas Medical Assn
Am Burn Assn
Am Coll Of Surgeons
Assn Of Academic Surgery
Eastern Assn For The Surgery O
Golden Key National Honor Soc

NPI Number

1831177138

James Hill Holmes IV, M.D.

Associate Professor, Surgery, General Institute for Regenerative Medicine

Research Interests

medical technology/devices, surgery/trauma/burns/trauma

Contact Information

Academic: 336-716-0549 | Department: 336-716-0549

Email: jholmes@wakehealth.edu

Recent Publications

Kearns R, Holmes J IV, Cairns B. Burn disaster preparedness and the southern region of the United States. South Med J. 2013;106(1):69-73.

Holmes JH IV, Dimick AR. American Burn Association Southern Burn Region--recently revised [letter]. J Burn Care Res. 2012;33(2):e94.

Orlando G, Wood KJ, De Coppi P, Baptista PM, Binder KW, Bitar KN, Breuer C, Burnett L, Christ G, Farney A, Figliuzzi M, Holmes JH IV, Koch K, Macchiarini P, Mirmalek Sani S-H, Opara E, Remuzzi A, Rogers J, Saul JM, Seliktar D,. Regenerative medicine as applied to general surgery. Ann Surg. 2012;255(5):867-880.

Orrey D, Bortsov A, Liberzon I, Shupp JW, Jones S, Hwang J, Jordan M, Holmes J, Haith L, Cairns B, McLean SA. Failure of propranolol to decrease anxiety and PTSD symptoms in a genotype-based RCT of patients with major thermal burn injury [abstract]. Biol Psychiatry. 2012;71(8 Suppl):56S.

Orrey D, Bortsov A, Shupp J, Jones S, Hwang J, Jordan M, Holmes J, Haith L, Cairns B, Liberzon I, McLean S. Individuals with elevated PTSD symptoms experience increased itch symptom morbidity after major burn injury [abstract]. Biol Psychiatry. 2012;71(8 Suppl):242S-243S.

Orrey DC, Bortsov AV, Hoskins JM, Shupp JW, Jones SW, Cicuto BJ, Hwang J, Jordan MH, Holmes JH, Haith LR, Roane BM, Diatchenko L, Cairns BA, McLean SA. Catechol-O-methyltransferase genotype predicts pain severity in hospitalized burn patients. J Burn Care Res. 2012;33(4):518-523.

Holmes JH IV, Carter JE, Neff LP, Cairns BA, d'Agostino RB Jr, Griffin LP, Meredith JW. The effectiveness of regionalized burn care: an analysis of 6,873 burn admissions in North Carolina from 2000 to 2007. J Am Coll Surg. 2011;212(4):487-495.

Mowery NT, Dougherty SD, Hildreth AN, Holmes JH IV, Chang MC, Martin RS, Hoth JJ, Meredith JW, Miller PR. Emergency department length of stay is an independent predictor of hospital mortality in trauma activation patients. J Trauma. 2011;70(6):1317-1325.

Carter JE, Neff LP, Holmes JH IV. Adherence to burn center referral criteria: are patients appropriately being referred?. J Burn Care Res. 2010;31(1):26-30.

Pendleton RA, Holmes JH IV. Systemic absorption of amphotericin B with topical 5% mafenide acetate/amphotericin B solution for grafted burn wounds: is it clinically relevant?. Burns. 2010;36(1):38-41.

Neff LP, Allman JM, Holmes JH. The use of theraputic plasma exchange (TPE) in the setting of refractory burn shock. Burns. 2010;36(3):372-378.

Peck MD, Pressman MA, Caruso DM, Edelman LS, Holmes JH IV, Hughes WB, Korentager RA, Saffle JR, Voigt DW. Reimbursement for out-of-state burn patients is not always lower than that for in-state patients at regional burn centers. J Burn Care Res. 2010;31(4):603-609.

Holmes JH IV. Nutrition and venous access In: Gracias VH, McKenney MG, Reilly PM, Velmahos GC, eds. Acute care surgery: a guide for general surgeons. New York: McGraw-Hill Medical;2009: 257-262.

Holmes JH IV. Critical issues in burn care. J Burn Care Res. 2008;29(6 Suppl 2):S180-S187.

Holmes JH IV. Critical issues in burn care. South Med J. 2008;101(12 Suppl):S6-S12.

Pendleton RA, Holmes JH IV. Systemic absorption of amphotericin B with topical 5% mafenide acetate/amphotericin B solution for grafted burn wounds: is it clinically relevant? [abstract]. South Med J. 2008;101(12 Suppl):S37.

Mattix KD, Tataria M, Holmes J, Kristoffersen K, Brown R, Groner J, Sciafe E, Mooney D, Nance M, Scherer L. Pediatric pancreatic trauma: predictors of nonoperative management failure and associated outcomes. J Pediatr Surg. 2007;42(2):340-344.

Tataria M, Nance ML, Holmes JH IV, Miller CC III, Mattix KD, Brown RL, Mooney DP, Scherer LRT III, Groner JI, Scaife ER, et al. Pediatric blunt abdominal injury: age is irrelevant and delayed operation is not detrimental. J Trauma. 2007;63(3):608-614.

Greenhalgh DG, Saffle JR, Holmes JH IV, Gamelli RL, Palmieri TL, Horton JW, Tompkins RG, Traber DL, Mozingo DW, Deitch EA, et al. American Burn Association Consensus Conference to define sepsis and infection in burns. J Burn Care Res. 2007;28(6):776-790.

Loveall CF, Manuel AL, Stansberry RD, Williams JH, Molnar JA, Holmes JH IV. White phosphorus and its ability to cause serious burns [abstract]. South Med J. 2007;100(12 Suppl):S16.

Nance ML, Holmes JH IV, Wiebe DJ. Timeline to operative intervention for solid organ injuries in children. J Trauma. 2006;61(6):1389-1392.