Profile

David Horita, Ph.D.

David Horita, Ph.D.

Associate Professor, Biochemistry
Comprehensive Cancer Center
Contact Information
Office:
336-716-2011
Email: dhorita@wakehealth.edu
Education & Training
  PhD University of Wisconsin-Madison 1994
  BA Carleton College 1998
Fellowship Natl Cancer Institute (NIH) 1999
David Horita, Ph.D.

David Horita, Ph.D.

Associate Professor, Biochemistry
Comprehensive Cancer Center
Contact Information
Office:
336-716-2011
Email: dhorita@wakehealth.edu
Research Interests
cancer/oncogenesis , immunology/allergy/inflammatio , structural biology
Recent Publications
Ghosh S, Salsbury FR Jr, Horita DA, Gmeiner WH. Zn2+ selectively stabilizes FdU-substituted DNA through a unique major groove binding motif. Nucleic Acids Res. 2011; 39(10):4490-4498.

Davis NY, McPhail LC, Horita DA. Backbone 1H, 15N, and 13C resonance assignments for the NOXO1 beta PX domain. Biomol NMR Assign. 2011; 5(2):139-141.

Lewis EM, Wilkinson AS, Davis NY, Horita DA, Wilkinson JC. Nondegradative ubiquitination of apoptosis inducing factor (AIF) by X-linked inhibitor of apoptosis at a residue critical for AIF-mediated chromatin degradation. Biochemistry. 2011; 50(51):11084-96.

Hall A, Parsonage D, Horita D, Karplus PA, Poole LB, Barbar E. Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds. Biochemistry. 2009; 48(25):5984-5993.

Hantgan RR, Stahle MC, Horita DA. Entropy drives integrin alpha IIb beta 3 : echistatin binding--evidence from surface plasmon resonance spectroscopy. Biochemistry. 2008; 47(9):2884-2892.

Hantgan RR, Stahle MC, Grant K, Horita DA. PAC-1 binding illuminates integrin priming mechanisms [abstract]. Arterioscler Thromb Vasc Biol. 2008; 28(6):e-139.

Rocco M, Rosano C, Weisel JW, Horita DA, Hantgan RR. Integrin conformational regulation: uncoupling extension/tail separation from changes in the head region by a multiresolution approach. Structure. 2008; 16(6):954-964.

Shen K, Sergeant S, Hantgan RR, McPhail LC, Horita DA. Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activation. Biochemistry. 2008; 47(34):8855-8865.

Hantgan RR, Stahle MC, Connor JH, Horita DA, Rocco M, McLane MA, Yakovlev S, Medved L. Integrin alphaIIbbeta3:ligand interactions are linked to binding-site remodeling. Protein Sci. 2006; 15(8):1893-1906.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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Last Updated 3/14/2012
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