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William G. Hundley, M.D.Wake Forest School of Medicine

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William G. Hundley, M.D.

Professor,



Clinical Interests

Vascular Biology and Function, Cardiac Magnetic Resonance Imaging, Cardiology (clinical), Echocardiography, Computed Tomography (CT)

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-6674
Department: 336-716-6125

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Education & Training

  • B.S., College of William & Mary, 1984
  • M.D., Medical College of Va., VCU, 1988
  • Internship, Parkland Memorial Hosp, 1989
  • Residency, Parkland Memorial Hosp, 1991
  • Fellowship, Parkland Memorial Hosp, 1996

Board Certifications

  • American Board of Internal Medicine, Cardiovascular Disease

NPI Number

  • 1194700484
William G. Hundley, M.D.

Doctor Rating

No Rating Available
Why No Ratings?

William G. Hundley, M.D.

Professor, Cardiology
Office of Women in Medicine and Science
Biomedical Engineering
Radiology

Research Interests

Dobutamine; Magnetic Resonance Imaging; Ventricular Function, Right; Myocardial Perfusion Imaging; Magnetic Resonance Angiography
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Contact Information

Academic: 336-716-6125 | Department: 336-716-6125

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Recent Publications

Reproducibility of functional aortic analysis using magnetic resonance imaging: the MESA. Noda C, Ambale Venkatesh B, Ohyama Y, Liu CY, Chamera E, Redheuil A, Teixido-Tura G, Chugh AR, Wu CO, Hundley GW [sic] [Hundley WG], Bluemke DA, Lima JA.. Eur Heart J Cardiovasc Imaging. 2016;17(8):909-917.

Adverse left ventricular remodeling and age assessed with cardiac MR imaging: the Multi-Ethnic Study of Atherosclerosis. Eng J, McClelland RL, Gomes AS, Hundley WG, Cheng S, Wu CO, Carr JJ, Shea S, Bluemke DA, Lima JA.. Radiology. 2016;278(3):714-722.

Ten-year longitudinal change in aortic stiffness assessed by cardiac MRI in the second half of the human lifespan: the Multi-Ethnic Study of Atherosclerosis. Ohyama Y, Teixido-Tura G, Ambale-Venkatesh B, Noda C, Chugh AR, Liu CY, Redheuil A, Stacey RB, Dietz H, Gomes AS, Prince MR, Evangelista A, Wu CO, Hundley WG, Bluemke DA, Lima JA.. Eur Heart J Cardiovasc Imaging. 2016;():.

Reduced long axis strain is associated with heart failure and cardiovascular events in the Multi-Ethnic Study of Atherosclerosis. Gjesdal O, Yoneyama K, Mewton N, Wu C, Gomes AS, Hundley G [sic] [Hundley WG], Prince M, Shea S, Liu K, Bluemke DA, Lima JA.. J Magn Reson Imaging. 2016;44(1):178-185.

Adiposity is associated with gender-specific reductions in left ventricular myocardial perfusion during dobutamine stress. Hall ME, Brinkley TE, Chughtai H, Morgan TM, Hamilton CA, Jordan JH, Stacey RB, Soots S, Hundley WG.. PLoS One. 2016;11(1):e0146519.

Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial. Kitzman DW, Brubaker P, Morgan T, Haykowsky M, Hundley G [sic] [Hundley WG], Kraus WE, Eggebeen J, Nicklas BJ.. JAMA. 2016;315(1):36-46.

Prognosis of low normal left ventricular ejection fraction in an asymptomatic population-based adult cohort: the Multiethnic Study of Atherosclerosis. Yeboah J, Rodriguez CJ, Qureshi W, Liu S, Carr JJ, Lima JA, Hundley WG, Herrington DM.. J Card Fail. 2016;():.

Longitudinal automated assessments of myocardial strain from cine MR in cancer patients receiving cardiotoxic chemotherapy [abstract]. Jolly M-P, Jordan JH, Hamilton CA, Hundley G [sic] [Hundley WG].. J Cardiovasc Magn Reson. 2016;18(Suppl 1):081.

Beta-blocker use is associated with higher renal tissue oxygenation in hypertensive patients suspected of renal artery stenosis. Hall ME, Rocco MV, Morgan TM, Hamilton CA, Jordan JH, Edwards MS, Hall JE, Hundley WG.. Cardiorenal Med. 2016;6(4):261-268.

Fibroblast growth factor-23 and cardiac MRI indices of myocardial fibrosis in the Multi-ethnic Study of Atherosclerosis [abstract]. Almahmoud MF, Herrington D, Hundley W, Jordan J, Kestenbaum B, Katz R, Michos E, Liu CY, Venkatesh BA, Lima J.. J Am Coll Cardiol. 2016;67(13 Suppl):1684.

Refection magnitude, a measure of arterial stiffness, predicts incident congestive heart failure in men but not women: Multi-ethnic Study of Atherosclerosis (MESA) [abstract]. Chester R, Horwich T, Srikanthan P, Gornbein J, Hundley G [sic] [Hundley WG], Watson K.. J Am Coll Cardiol. 2016;67(13 Suppl):1314.

Association of aortic stiffness with left ventricular remodeling and reduced left ventricular function measured by magnetic resonance imaging: the Multi-Ethnic Study of Atherosclerosis. Ohyama Y, Ambale-Venkatesh B, Noda C, Chugh AR, Teixido-Tura G, Kim JY, Donekal S, Yoneyama K, Gjesdal O, Redheuil A, Liu CY, Nakamura T, Wu CO, Hundley WG, Bluemke DA, Lima JA.. Circ Cardiovasc Imaging. 2016;9(7):e004426.

Increased cardiovascular stiffness and impaired age-related functional status. Andersen MM, Kritchevsky SB, Morgan TM, Hire DG, Vasu S, Brinkley TE, Kitzman DW, Hamilton CA, Soots S, Hundley WG.. J Gerontol A Biol Sci Med Sci. 2015;70(5):545-553.

Right ventricular stress-induced perfusion defects and late gadolinium enhancement in coronary artery disease. Milks MW, Upadhya B, Hall ME, Vasu S, Hundley WG, Stacey RB.. J Comput Assist Tomogr. 2015;39(2):185-188.

Evaluation and management of left ventricular noncompaction cardiomyopathy. Stacey RB, Caine AJ Jr, Hundley WG.. Curr Heart Fail Rep. 2015;12(1):61-67.

Cigarette smoking and cardiovascular events: role of inflammation and subclinical atherosclerosis: the Multiethnic Study of Atherosclerosis. McEvoy JW, Blaha MJ, DeFilippis AP, Lima JA, Bluemke DA, Hundley WG, Min JK, Shaw LJ, Lloyd-Jones DM, Barr RG, Budoff MJ, Blumenthal RS, Nasir K.. Arterioscler Thromb Vasc Biol. 2015;35(3):700-709.

Abnormal stress-related measures of arterial stiffness in middle-aged and elderly men and women with impaired fasting glucose at risk for a first episode of symptomatic heart failure. Vasu S, Morgan TM, Kitzman DW, Bertoni A, Stacey RB, Hamilton C, Chiles C, Thohan V, Hundley WG.. J Am Heart Assoc. 2015;4(1):e000991.

Chronic statin administration may attenuate early anthracycline-associated declines in left ventricular ejection function. Chotenimitkhun R, D'Agostino R Jr, Lawrence JA, Hamilton CA, Jordan JH, Vasu S, Lash TL, Yeboah J, Herrington DM, Hundley WG.. Can J Cardiol. 2015;31(3):302-307.

Evolution of aortic wall thickness and stiffness with atherosclerosis: long-term follow up from the Multi-Ethnic Study of Atherosclerosis. Liu CY, Chen D, Bluemke DA, Wu CO, Teixido-Tura G, Chugh A, Vasu S, Lima JA, Hundley WG.. Hypertension. 2015;65(5):1015-1019.

Relationship of cigarette smoking with inflammation and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis. McEvoy JW, Nasir K, DeFilippis AP, Lima JA, Bluemke DA, Hundley WG, Barr RG, Budoff MJ, Szklo M, Navas-Acien A, Polak JF, Blumenthal RS, Post WS, Blaha MJ.. Arterioscler Thromb Vasc Biol. 2015;35(4):1002-1010.

The association between cardiovascular risk and cardiovascular magnetic resonance measures of fibrosis: the Multi-Ethnic Study of Atherosclerosis (MESA). Yi CJ, Wu CO, Tee M, Liu CY, Volpe GJ, Prince MR, Hundley GW [sic] [Hundley WG], Gomes AS, van der Geest RJ, Heckbert S, Lima JA, Bluemke DA.. J Cardiovasc Magn Reson. 2015;17(1):15.

Mechanism of decreased sensitivity of dobutamine associated left ventricular wall motion analyses for appreciating inducible ischemia in older adults. Vasu S, Little WC, Morgan TM, Stacey RB, Ntim WO, Hamilton C, Thohan V, Chiles C, Hundley WG.. J Cardiovasc Magn Reson. 2015;17(1):26.

Myocardial extracellular volume is elevated in cancer survivors treated with anthracycline-based chemotherapy compared to cancer-free peers and newly diagnosed and untreated cancer patients: a single-center observational study of the. Jordan JH, Vasu S, Morgan T, D'Agostino R, Melendez GC, Hall M, Hamilton C, Arai A, Liu S, Liu C-Y, Lima J, Bluemke D, Hundley W.. J Am Coll Cardiol. 2015;65(10 Suppl):A1081.

Visceral adiposity and left ventricular remodeling: the Multi-Ethnic Study of Atherosclerosis. Abbasi SA, Hundley WG, Bluemke DA, Jerosch-Herold M, Blankstein R, Petersen SE, Rider OJ, Lima JA, Allison MA, Murthy VL, Shah RV.. Nutr Metab Cardiovasc Dis. 2015;25(7):667-676.

Noninvasive imaging of flow and vascular function in disease of the aorta. Whitlock MC, Hundley WG.. JACC Cardiovasc Imaging. 2015;8(9):1094-1106.

Relation of pre-anthracycline serum bilirubin levels to left ventricular ejection fraction after chemotherapy. Vera T, D'Agostino RB Jr, Jordan JH, Whitlock MC, Melendez GC, Lamar ZS, Porosnicu M, Bonkovsky HL, Poole LB, Hundley WG.. Am J Cardiol. 2015;116(11):1752-1755.

Prognostic utility of cardiovascular magnetic resonance upright maximal treadmill exercise testing. Sukpraphrute B, Drafts BC, Rerkpattanapipat P, Morgan TM, Kirkman PM, Ntim WO, Hamilton CA, Cockrum RL, Hundley WG.. J Cardiovasc Magn Reson. 2015;17(1):103.

Cancer and its association with the development of coronary artery calcification: an assessment from the Multi-Ethnic Study of Atherosclerosis. Whitlock MC, Yeboah J, Burke GL, Chen H, Klepin HD, Hundley WG.. J Am Heart Assoc. 2015;4(11):e002533.

Clinical significance of intermediate left ventricular trabeculations in cardiac magnetic resonance. Stacey RB, Milks MW, Deutsch C, Upadhya B, Hundley WG, Thohan V.. Acta Cardiol. 2015;70(5):588-593.

Beta blockers improve renal tissue oxygenation in hypertensive patients suspected of renal artery stenosis [abstract]. Hall ME, Rocco MV, Morgan TM, Hamilton CA, Jordan JH, Edwards MS, Hall JE, Hundley WG.. Circulation. 2015;132(Suppl 3):A9839.

Information maximizing component analysis of left ventricular remodeling due to myocardial infarction. Zhang X, Ambale-Venkatesh B, Bluemke DA, Cowan BR, Finn JP, Kadish AH, Lee DC, Lima JA, Hundley WG, Suinesiaputra A, Young AA, Medrano-Gracia P.. J Transl Med. 2015;13():343.

COCATS 4 Task Force 8: training in cardiovascular magnetic resonance imaging. Kramer CM, Hundley WG, Kwong RY, Martinez MW, Raman SV, Ward RP.. J Am Coll Cardiol. 2015;65(17):1822-1831.

Determinants and normal values of ascending aortic diameter by age, gender, and race/ethnicity in the Multi-Ethnic Study of Atherosclerosis (MESA). Turkbey EB, Jain A, Johnson C, Redheuil A, Arai AE, Gomes AS, Carr J, Hundley WG, Teixido-Tura G, Eng J, Lima JA, Bluemke DA.. J Magn Reson Imaging. 2014;39(2):360-368.

Relation of thoracic aortic distensibility to left ventricular area (from the Multi-Ethnic Study of Atherosclerosis [MESA]). Al-Mallah MH, Nasir K, Katz R, Lima JA, Bluemke DA, Blumenthal RS, Mao S, Hundley WG, Budoff MJ.. Am J Cardiol. 2014;113(1):178-182.

Right ventricular morphology and systolic function in left ventricular noncompaction cardiomyopathy. Stacey RB, Andersen M, Haag J, Hall ME, McLeod G, Upadhya B, Hundley WG, Thohan V.. Am J Cardiol. 2014;113(6):1018-1023.

Chronic diuretic therapy attenuates renal BOLD magnetic resonance response to an acute furosemide stimulus. Hall ME, Rocco MV, Morgan TM, Hamilton CA, Edwards MS, Jordan JH, Hurie JB, Hundley WG.. J Cardiovasc Magn Reson. 2014;16(1):17.

Interstitial fibrosis, left ventricular remodeling, and myocardial mechanical behavior in a population-based multiethnic cohort: the Multi-Ethnic Study of Atherosclerosis (MESA) Study. Donekal S, Venkatesh BA, Liu YC, Liu CY, Yoneyama K, Wu CO, Nacif M, Gomes AS, Hundley WG, Bluemke DA, Lima JA.. Circ Cardiovasc Imaging. 2014;7(2):292-302.

Small, short-duration, dobutamine-induced perfusion defects are not associated with adverse prognosis in intermediate-risk individuals receiving cardiovascular magnetic resonance stress imaging. Jordan JH, Haag JC, Morgan TM, Vasu S, Stacey B, Hamilton C, Robinson K, Kitzman D, Thohan V, Hundley WG.. J Comput Assist Tomogr. 2014;38(3):427-433.

ACCF/AHA/ASE/ASNC/HFSA/HRS/SCAI/SCCT/SCMR/STS 2013 multimodality appropriate use criteria for the detection and risk assessment of stable ischemic heart disease. Wolk MJ, Bailey SR, Doherty JU, Douglas PS, Hendel RC, Kramer CM, Min JK, Patel MR, Rosenbaum L, Shaw LJ, Stainback RF, Allen JM, Brindis RG, Kramer CM, Shaw LJ, Cerqueira MD, Chen J, Dean LS, Fazel R, Hundley WG, Itchhaporia D,.. J Card Fail. 2014;20(2):65-90.

ACCF/AHA/ASE/ASNC/HFSA/HRS/SCAI/SCCT/SCMR/STS 2013 multimodality appropriate use criteria for the detection and risk assessment of stable ischemic heart disease. Ronan G, Wolk MJ, Bailey SR, Doherty JU, Douglas PS, Hendel RC, Kramer CM, Min JK, Patel MR, Rosenbaum L, Shaw LJ, Stainback RF, Allen JM, Brindis RG, Kramer CM, Shaw LJ, Cerqueira MD, Chen J, Dean LS, Fazel R, Hundley WG, Itchhaporia D,.. J Nucl Cardiol. 2014;21(1):192-220.

Reply: diagnostic problem of LV hypertrabeculation/noncompaction? [letter]. Stacey RB, Andersen MM, St Clair M, Hundley WG, Thohan V.. JACC Cardiovasc Imaging. 2014;7(5):533.

Periaortic fat and cardiovascular risk: a comparison of high-risk older adults and age-matched healthy controls. Brinkley TE, Leng X, Chughtai HL, Nicklas BJ, Kritchevsky SB, Ding J, Kitzman DW, Hundley WG.. Int J Obes (Lond). 2014;38(11):1397-1402.

Diastolic function assessed from tagged MRI predicts heart failure and atrial fibrillation over an 8-year follow-up period: the multi-ethnic study of atherosclerosis. Ambale-Venkatesh B, Armstrong AC, Liu CY, Donekal S, Yoneyama K, Wu CO, Gomes AS, Hundley GW [sic] [Hundley WG], Bluemke DA, Lima JA.. Eur Heart J Cardiovasc Imaging. 2014;15(4):442-449.

Association of CMR-measured LA function with heart failure development: results from the MESA study. Habibi M, Chahal H, Opdahl A, Gjesdal O, Helle-Valle TM, Heckbert SR, McClelland R, Wu C, Shea S, Hundley G [sic] [Hundley WG], Bluemke DA, Lima JA.. JACC Cardiovasc Imaging. 2014;7(6):570-579.

Workstations with circutis for generating images of global injury. Hundley WG, D'Agostino RB, Hamilton CA, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 8,660,327. 2014 Feb 25. 2014;():.

Tissue evaluation using global characteristics of non-invasive imaging and systems for determining global tissue characteristics of images. Hundley WG, Lane KS, Morgan TM, Hamilton CA, Torti FM, inventors; Wake Forest University Health Sciences, assignee.. Canada patent CA 2,555,373. 2014 Apr 29. 2014;():.

Noninvasive imaging of cardiovascular injury related to the treatment of cancer. Kongbundansuk S, Hundley WG.. JACC Cardiovasc Imaging. 2014;7(8):824-838.

Longitudinal assessment of concurrent changes in left ventricular ejection fraction and left ventricular myocardial tissue characteristics after administration of cardiotoxic chemotherapies using T1-weighted and T2-weighted cardiovascular magnetic. Jordan JH, D'Agostino RB Jr, Hamilton CA, Vasu S, Hall ME, Kitzman DW, Thohan V, Lawrence JA, Ellis LR, Lash TL, Hundley WG.. Circ Cardiovasc Imaging. 2014;7(6):872-879.

The relationship of cigarette smoking with inflammation and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis [abstract]. McEvoy JW, Nasir K, DeFilippis AP, Lima JAC, Bluemke DA, Hundley WG, Barr RG, Budoff MJ, Szklo M, Navas-Acien A, Polak JF, Blumenthal RS, Post WS, Blaha MJ.. Ir J Med Sci. 2014;183(Suppl 8):S421.

The relationship of left ventricular trabeculation to ventricular function and structure over a 9.5-year follow-up: the MESA study. Zemrak F, Ahlman MA, Captur G, Mohiddin SA, Kawel-Boehm N, Prince MR, Moon JC, Hundley WG, Lima JA, Bluemke DA, Petersen SE.. J Am Coll Cardiol. 2014;64(19):1971-1980.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Cardiology

Clinical Interests

Vascular Biology and Function, Cardiac Magnetic Resonance Imaging, Cardiology (clinical), Echocardiography, Computed Tomography (CT)

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