Matthew J. Jorgensen, Ph.D.Wake Forest School of Medicine

Matthew J. Jorgensen, Ph.D.

Associate Professor,

Contact Information

Academic: 336-716-6935 | Department: 336-716-6935


Education & Training

  • B.S., University of Massachusetts-Amherst, 1989
  • M.A., University of California-Riverside, 1991
  • Ph.D., University of California-Riverside, 1994
  • Fellowship, Behavioral Science, University of California-Los A, 2000
Matthew J. Jorgensen, Ph.D.

Matthew J. Jorgensen, Ph.D.

Associate Professor, Pathology-Comparative Medicine

Research Interests

drugs/therapeutic agents pharm, growth & development, immunology/allergy/inflammatio, infectious diseases, metabolism, model development, neurosciences/behavior, nutrition

Contact Information

Academic: 336-716-6935 | Department: 336-716-6935


Recent Publications

Chittoor G, Pajewski NM, Voruganti VS, Comuzzie AG, Clarkson TB [deceased], Nudy M, Schnatz PF, Kaplan JR, Jorgensen MJ. Vitamin D heritability and effect of pregnancy status in vervet monkeys (Chlorocebus aethiops sabaeus) under conditions of modest and high dietary supplementation. Am J Phys Anthropol. 2016;159(4):639-645.

Miller LR, Jorgensen MJ, Kaplan JR, Seeds MC, Rahbar E, Morgan TM, Welborn A, Chilton SM, Gillis J, Hester A, Rukstalis M, Sergeant S, Chilton FH. Alterations in levels and ratios of n-3 and n-6 polyunsaturated fatty acids in the temporal cortex and liver of vervet monkeys from birth to early adulthood. Physiol Behav. 2016;156():71-78.

Schmitt CA, Service SK, Cantor RM, Jasinska AJ, Jorgensen MJ, Kaplan JR, Freimer NB. Maternal effects influence the heritability of adult obesity traits but not obesogenic growth trajectories in vervet monkeys (Chlorocebus spp.) [abstract]. Am J Phys Anthropol. 2015;156(Suppl 60):279.

Kim JR, Holbrook BC, Hayward SL, Blevins LK, Jorgensen MJ, Kock ND, De Paris K, D'Agostino R Jr, Aycock ST, Mizel SB, Parks GD, Alexander-Miller MA. Inclusion of flagellin during vaccination against influenza enhances recall responses in nonhuman primate neonates. J Virol. 2015;89(14):7291-7303.

Huang YS, Ramensky V, Service SK, Jasinska AJ, Jung Y, Choi OW, Cantor RM, Juretic N, Wasserscheid J, Kaplan JR, Jorgensen MJ, Dyer TD, Dewar K, Blangero J, Wilson RK, Warren W, Weinstock GM, Freimer NB. Sequencing strategies and characterization of 721 vervet monkey genomes for future genetic analyses of medically relevant traits. BMC Biol. 2015;13():41.

Chichester L, Gee MK, Jorgensen MJ, Kaplan JR. Hematology and clinical chemistry measures during and after pregnancy and age- and sex-specific reference intervals in African green monkeys (Chlorocebus aethiops sabaeus). J Am Assoc Lab Anim Sci. 2015;54(4):359-367.

Warren WC, Jasinska AJ, Garcia-Perez R, Svardal H, Tomlinson C, Rocchi M, Archidiacono N, Capozzi O, Minx P, Montague MJ, Kyung K, Hillier LW, Kremitzki M, Graves T, Chiang C, Hughes J, Tran N, Huang Y, Ramensky V, Choi OW, Jung YJ, Schmitt CA,. The genome of the vervet (Chlorocebus aethiops sabaeus). Genome Res. 2015;25(12):1921-1933.

Jorgensen MJ, Lambert KR, Breaux SD, Baker KC, Snively BM, Weed JL. Pair housing of vervets/African green monkeys for biomedical research. Am J Primatol. 2015;():.

Jasinska AJ, Service S, Fears S, Zelaya I, Huang Y, Navarro L, Jorgensen M, Weinstock G, Warren W, Woods R, Coppola G, Freimer N. Genetic regulation of hippocampal size trait in vervet monkeys [abstract]. Am J Primatol. 2015;77(Suppl 1):55.

Fairbanks LA, Jorgensen MJ, Bailey JN. Novelty seeking in vervets: genetic and environmental influences [abstract]. Am J Phys Anthropol. 2014;153(Suppl 58):115-116.

Schmitt CA, Service S, Cantor RM, Jasinska AJ, Jorgensen MJ, Kaplan JR, Freimer NB. Heritability of obesogenic growth trajectories during development in captive vervet monkeys (Chlorocebus aethiops sabaeus) [abstract]. Am J Phys Anthropol. 2014;153(Suppl 58):231-232.

Macharia AN, Cerling TE Jorgensen MJ, Kaplan JR. The hair-diet C-13 and N-15 fractionation in Chlorocebus aethiops sabaeus based on a control diet study. Ann Zool Fennici. 2014;51(1-2):66-72.

Schmitt CA, Service S, Cantor RM, Jasinska AJ, Jorgensen MJ, Kaplan JR, Freimer NB. High genetic heritability of obesogenic growth in captive vervet monkey (chlorocebus SPP) [abstract]. Am J Primatol. 2014;76(Suppl 1):74.

Schmitt CA, Service S, Cantor RM, Jasinska AJ, Jorgensen MJ, Kaplan JR, Freimer NB. Genetics and development of obesity in captive vervet monkeys (Chlorocebus aethiops sabaeus) [abstract]. Am J Phys Anthropol. 2013;150(Suppl 56):243.

Kalinin S, Willard SL, Shively CA, Kaplan JR, Register TC, Jorgensen MJ, Polak PE, Rubinstein I, Feinstein DL. Development of amyloid burden in African Green monkeys. Neurobiol Aging. 2013;34(10):2361-2369.

Voruganti VS, Jorgensen MJ, Kaplan JR, Kavanagh K, Rudel LL, Temel R, Fairbanks LA, Comuzzie AG. Significant genotype by diet (G X D) interaction effects on cardiometabolic responses to a pedigree-wide, dietary challenge in vervet monkeys (Chlorocebus aethiops sabaeus). Am J Primatol. 2013;75(5):491-499.

Plate JF, Bates CM, Mannava S, Smith TL, Jorgensen MJ, Register TC, Stehle JR, High KP, Shively CA, Kaplan JR, Saul KR, Tuohy CJ. Age-related degenerative functional, radiographic, and histological changes of the shoulder in nonhuman primates. J Shoulder Elbow Surg. 2013;22(8):1019-1029.

O'Grady SP, Valenzuela LO, Remien CH, Enright LE, Jorgensen MJ, Kaplan JR, Wagner JD, Cerling TE, Ehleringer JR. Hydrogen and oxygen isotope ratios in body water and hair: modeling isotope dynamics in nonhuman primates. Am J Primatol. 2012;74(7):651-660.

Jasinska AJ, Lin MK, Service S, Choi O-W, DeYoung J, Grujic O, Kong S-Y, Jung Y, Jorgensen MJ, Fairbanks LA, Turner T, Cantor RM, Wasserscheid J, Dewar K, Warren W, Wilson RK, Weinstock G, Jentsch JD, Freimer NB. A non-human primate system for large-scale genetic studies of complex traits. Hum Mol Genet. 2012;21(15):3307-3316.

Fairbanks LA, Jorgensen MJ, Bales KL. Phenotypic and genetic correlations between plasma oxytocin and affiliative approach in vervet monkeys [abstract]. Am J Primatol. 2012;74(Suppl 1):54.

Jorgensen MJ, Rudel LL, Kavanagh K, Jasinska AJ, Freimer NB, Jentsch JD, Fairbanks LA, Fallon MT, Kaplan JR. The vervet research colony as a biomedical resource [abstract]. Am J Primatol. 2012;74(Suppl 1):68.

Kavanagh K, Wylie AT, Chavanne TJ, Jorgensen MJ, Voruganti VS, Comuzzie AG, Kaplan JR, McCall CE, Kritchevsky SB. Aging does not reduce heat shock protein 70 in the absence of chronic insulin resistance. J Gerontol A Biol Sci Med Sci. 2012;67(10):1014-1021.

Jorgensen MJ, Rudel LL, Nudy M, Kaplan JR, Clarkson TB, Pajewski NM, Schnatz PF. 25(OH)D3 and cardiovascular risk factors in female nonhuman primates. J Womens Health. 2012;21(9):959-965.

Laudenslager ML, Jorgensen MJ, Fairbanks LA. Developmental patterns of hair cortisol in male and female nonhuman primates: lower hair cortisol levels in vervet males emerge at puberty. Psychoneuroendocrinology. 2012;37(10):1736-1739.

Fairbanks LA, Way BM, Breidenthal SE, Bailey JN, Jorgensen MJ. Maternal and offspring dopamine D4 receptor genotypes interact to influence juvenile impulsivity in vervet monkeys. Psychol Sci. 2012;23(10):1099-1104.

Woods RP, Fears SC, Jorgensen MJ, Fairbanks LA, Toga AW, Freimer NB. A web-based brain atlas of the vervet monkey, Chlorocebus aethiops. Neuroimage. 2011;54(3):1872-1880.

Kavanagh K, Dozier BL, Chavanne TJ, Fairbanks LA, Jorgensen MJ, Kaplan JR. Fetal and maternal factors associated with infant mortality in vervet monkeys. J Med Primatol. 2011;40(1):27-36.

Klimentidis YC, Beasley TM, Lin H-Y, Murati G, Glass GE, Guyton M, Newton W, Jorgensen M, Heymsfield SB, Kemnitz J, et al. Canaries in the coal mine: a cross-species analysis of the plurality of obesity epidemics. Proc Biol Sci. 2011;278(1712):1626-1632.

Laudenslager ML, Jorgensen MJ, Grzywa R, Fairbanks LA. A novelty seeking phenotype is related to chronic hypothalamic-pituitary-adrenal activity reflected by hair cortisol. Physiol Behav. 2011;104(2):291-295.

Fairbanks LA, Jorgensen MJ, Bailey JN, Breidenthal SE, Grzywa R, Laudenslager ML. Heritability and genetic correlation of hair cortisol in vervet monkeys in low and higher stress environments. Psychoneuroendocrinology. 2011;36(8):1201-1208.

Fairbanks LA, Bailey JN, Breidenthal SE, Laudenslager ML, Kaplan JR, Jorgensen MJ. Environmental stress alters genetic regulation of novelty seeking in vervets [abstract]. Am J Primatol. 2011;73(Suppl 1):84.

Kuhrt D, Nusbaum R, Garlena R, Nguyen T, Jorgensen MJ, Silvestri G, Kaplan J, Apetrei C, Pandrea I. CCR5 expression on CD4+T cells and not CD4 downregulation impacts the efficacy of SIVagm mucosal transmission in African green monkeys (AGMS) [abstract]. J Med Primatol. 2011;40(4):256.

Voruganti V, Jorgensen MJ, Kaplan JR, Kauanagh K [sic] [Kavanagh K], Rudel LL, Temel R, Fairbanks LA, Comuzzie AG. Significant genotype by diet (GXD) interaction effects on cardiometabolic responses to a pedigree-wide, dietary challenge in Vervet monkeys (Chlorocebus aethiops sabaeus) [abstract]. Am J Primatol. 2011;73(Suppl 1):84.

Wiseman RW, Tuscher JJ, Blanchard JL, Jorgensen MJ, Jasinska AJ, Freimer NB, Schmitz JE, O'Connor DH. Caribbean-origin African green monkeys exhibit remarkably limited major histocompatibilty complex (MHC) diversity [abstract]. J Med Primatol. 2011;40(4):262.

Jorgensen MJ, Schnatz PF, Rudel LL, Nudy M, Kaplan JR, Clarkson TB. Low plasma concentrations of vitamin D3 are associated with increased cardiovascular risk factors in a female nonhuman primate model [abstract]. Menopause. 2011;18(12):1345.

Fears SC, Scheibel K, Abaryan Z, Lee C, Service SK, Jorgensen MJ, Fairbanks LA, Cantor RM, Freimer NB, Woods RP. Anatomic brain asymmetry in vervet monkeys. PLoS ONE. 2011;6(12):e28243.

Fairbanks LA, Blau K, Jorgensen MJ. High-fiber diet promotes weight loss and affects maternal behavior in vervet monkeys. Am J Primatol. 2010;72(3):234-241.

Cann JA, Kavanagh K, Jorgensen MJ, Mohanan S, Howard TD, Gray SB, Hawkins GA, Fairbanks LA, Wagner JD. Clinicopathologic characterization of naturally occurring diabetes mellitus in vervet monkeys. Vet Pathol. 2010;47(4):713-718.

Fairbanks LA, Laudenslager ML, Jorgensen MJ. Evidence for additive effects of genes and environment on cortisol response to stress in adult female vervets [abstract]. Am J Primatol. 2010;72(Suppl 1):29-30.

Appt SE, Ethun KF, Jorgensen MJ, Wagner JD. Do diet and ovarian reserve predict risk for development of the metabolic syndrome? [abstract]. Menopause. 2010;17(6):1218.

Fears SC, Melega WP, Service SK, Lee C, Chen K, Tu Z, Jorgensen MJ, Fairbanks LA, Cantor RM, Freimer NB, et al. Identifying heritable brain phenotypes in an extended pedigree of vervet monkeys. J Neurosci. 2009;29(9):2867-2875.

Wagner JD, Jorgensen MJ, Cline JM, Lees CJ, Franke AA, Zhang L, Ayers MR, Schultz C, Kaplan JR. Effects of soy vs. casein protein on body weight and glycemic control in female monkeys and their offspring. Am J Primatol. 2009;71(9):802-811.

Jasinska AJ, Service S, Choi O, DeYoung J, Grujic O, Kong S, Jorgensen MJ, Bailey J, Breidenthal S, Fairbanks LA, et al. Identification of brain transcriptional variation reproduced in peripheral blood: an approach for mapping brain expression traits. Hum Mol Genet. 2009;18(22):4415-4427.

Shively CA, Register TC, Kritchevsky S, Carr JJ, Kaplan JR, Jorgensen MJ, Bennett AJ. A primate model of physical function [abstract]. Gerontologist. 2009;49(Suppl 2):65-66.

Fairbanks L, Service S, Jorgensen MJ, Bailey JN, Breidenthal S, Jasinska AJ, Freimer NB. Possible quantitative trait loci for impulsivity in vervet monkeys [abstract]. Am J Primatol. 2009;71(Suppl 1):94.

Melega WP, Jorgensen MJ, Lacan G, Way BM, Pham J, Morton G, Cho AK, Fairbanks LA. Long-term methamphetamine administration in the vervet monkey models aspects of a human exposure: brain neurotoxicity and behavioral profiles. Neuropsychopharmacology. 2008;33(6):1441-1452.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Pathology-Comparative Medicine

Matthew J. Jorgensen, Ph.D.

Matthew J. Jorgensen, Ph.D.

Associate Professor, Pathology-Comparative Medicine

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