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Anushree N. KarkhanisWake Forest School of Medicine

Anushree N. Karkhanis

Instructor,

Contact Information

Academic: 336-716-2671 | Department: 336-716-2011

Email: akarkhan@wakehealth.edu

Education & Training

  • Ph.D., Rutgers State University-Newark Campus, 2010
Anushree N. Karkhanis

Anushree N. Karkhanis

Instructor, Physiology & Pharmacology
Office of Women in Medicine and Science

Research Interests

Dopamine; Ethanol; Social Isolation; Nucleus Accumbens; Norepinephrine
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Contact Information

Academic: 336-716-2671 | Department: 336-716-2011

Email: akarkhan@wakehealth.edu

Recent Publications

Social isolation stress increases KAPPA opioid receptor function on dopamine terminals in the nucleus accumbens of rats [abstract]. Karkhanis AN, Leussen D, Weiner JL, Chen R, Jones SR.. Alcohol. 2017;60():215.

Regulation of dopamine and dynorphin/KOR function by chronic ethanol and withdrawal in mice and monkeys [abstract]. Holleran KM, Karkhanis A, Rose JH, Siciliano CA, Grant KA, Jones SR.. Alcohol. 2017;60():220.

Chronic stress and ethanol-mediated alterations in norepineprhine transmission in mesolimbic circuitry [abstract]. Karkhanis AN, Jones SR.. Alcohol Clin Exp Res. 2017;41(Suppl 1):323A.

Adolescent social isolation as a model of heightened vulnerability to comorbid alcoholism and anxiety disorders. Butler TR, Karkhanis AN, Jones SR, Weiner JL.. Alcohol Clin Exp Res. 2016;40(6):1202-1214.

The individual and combined effects of phenmetrazine and mgluR2/3 agonist LY379268 on the motivation to self-administer cocaine. Karkhanis AN, Beveridge TJ, Blough BE, Jones SR, Ferris MJ.. Drug Alcohol Depend. 2016;166():51-60.

Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: role of kappa opioid receptors. Karkhanis AN, Huggins KN, Rose JH, Jones SR.. Neuropharmacology. 2016;110(Pt A):190-197.

Distinct effects of nalmefene on dopamine uptake rates and kappa opioid receptor activity in the nucleus accumbens following chronic intermittent ethanol exposure. Rose JH, Karkhanis AN, Steiniger-Brach B, Jones SR.. Int J Mol Sci. 2016;17(8):1216.

Hyperactive KAPPA opioid receptors and increased presynaptic inhibitory regulation of dopamine after chronic alcohol exposure in mice and monkeys [abstract]. Siciliano CA, Rose JH, Fordahl SC, Karkhanis AN, Melchior JR, Jones SR.. Alcohol Clin Exp Res. 2016;40(Suppl 1):288A.

Chronic intermittent ethanol exposure reduces presynaptic dopamine neurotransmission in the mouse nucleus accumbens. Karkhanis AN, Rose JH, Huggins KN, Konstantopoulos JK, Jones SR.. Drug Alcohol Depend. 2015;150():24-30.

Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala. Karkhanis AN, Alexander NJ, McCool BA, Weiner JL, Jones SR.. Synapse. 2015;69(8):385-395.

Social isolation stress increases K-opioid receptor activity in the nucleus accumbens shell and core [abstract]. Karkhanis AN, Rose JH, Weiner JL, Jones SR.. Alcohol Clin Exp Res. 2015;39(Suppl 1):121A.

Adolescent social isolation as a model of alcohol addiction vulnerability [abstract]. Weiner JL, Karkhanis AN, Rau A, Skelly MJ, Jones SR.. Alcohol Alcohol. 2015;50(Suppl 1):SY17-2.

Social isolation rearing increases dopamine uptake and psychostimulant potency in the striatum. Yorgason JT, Calipari ES, Ferris MJ, Karkhanis AN, Fordahl SC, Weiner JL, Jones SR.. Neuropharmacology. 2015;101():471-479.

Early life stress increases behavioral and neurobiological risk factors of alcohol addiction in male Long Evans rats [abstract]. Karkhanis A, Skelly MJ, Rau A, Yorgason J, Chappell A, Carter E, Jones S, McCool B, Weiner J.. Alcohol. 2014;48(2):161.

Social isolation stress augments dopamine and norepinephrine responses to ethanol in the nucleus accumbens and the basolateral amygdala [abstract]. Karkhanis AN, McCool BA, Weiner JL, Jones SR.. Alcohol Clin Exp Res. 2014;38(Suppl 1):81A.

Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood. Karkhanis AN, Locke JL, McCool BA, Weiner JL, Jones SR.. Alcohol Clin Exp Res. 2014;38(11):2770-2779.

Social isolation rearing increases dopamine and norepinephrine responses to ethanol and K-opioid receptor activity in nucleus accumbens [abstract]. Karkhanis AN, Konstantopoulos J, Locke J, Weiner JL, Jones SR.. Alcohol Clin Exp Res. 2013;37(Suppl 2):240A.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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